Displaying drugs 301 - 325 of 8039 in total
Doxazosin
Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and hypertension. Other members of this drug class include Prazosin, Terazosin, Tamsulosin, and Alfuzosin. Because of its long-lasting effects, doxazosin can be administered once a day. It is marketed by Pfizer and was initially approved...
Approved
Matched Description: … [A180661] Because of its long-lasting effects, doxazosin can be administered once a day. ... Other members of this drug class include [Prazosin], [Terazosin], [Tamsulosin], and [Alfuzosin]. ... Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms …
Nalidixic acid
Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Approved
Investigational
Matched Description: … It is an inhibitor of the A subunit of bacterial DNA gyrase. …
Fluoroestradiol F-18
Fluoroestradiol F-18 is an imaging agent used with positron emission tomography (PET) to detect estrogen receptor-positive breast cancer lesions. The ability to image ER-positive tumors in vivo is advantageous in that, while helping to visualize tumor progression/regression, it may also be used to assess for heterogeneity in ER expression across...
Approved
Temazepam
Temazepam, like many other similar and related benzodiazepines, acts as a gamma-aminobutyric acid (GABA) modulator and is capable of eliciting a variety of actions including sedation, hypnosis, skeletal muscle relaxation, anticonvulsant activity, and anxiolytic action [A175207, A175210, F3718, F3721].
Although the chemical synthesis of temazepam was established by 1965 ,...
Approved
Investigational
Matched Description: … sees millions of prescriptions every year. ... similar and related benzodiazepines, acts as a gamma-aminobutyric acid (GABA) modulator and is capable of ... eliciting a variety of actions including sedation, hypnosis, skeletal muscle relaxation, anticonvulsant …
Tocopherol
Tocopherol exists in four different forms designated as α, β, δ, and γ. They present strong antioxidant activities, and it is determined as the major form of vitamin E. Tocopherol, as a group, is composed of soluble phenolic compounds that consist of a chromanol ring and a 16-carbon phytyl chain....
Approved
Investigational
Matched Description: … Tocopherol, as a group, is composed of soluble phenolic compounds that consist of a chromanol ring and ... The classification of the tocopherol molecules is designated depending on the number and position of ... for the use of human consumption. …
Nelarabine
Nelarabine is an antineoplastic agent that is typically used to treat acute T-cell lymphoblastic leukemia, particularly T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL), in both adult and pediatric patients whose disease has not responded to or has relapsed following at least two chemotherapy regimens. T-cell acute lymphoblastic...
Approved
Investigational
Matched Description: … lymphoma having this T-cells variation of the disease. ... and a fast-track designation by the FDA to address the unmet therapeutic needs of these cancers. ... acute lymphoblastic leukemia and lymphoma are relatively rare T-cells malignancy, with only 20 to 25% of …
Tiopronin
Tiopronin is a prescription thiol drug used primarily in the treatment of severe homozygous cystinuria. Patients with cystinuria excrete high levels of cystine in their urine and are at risk for kidney stone formation. Tiopronin is used as a second-line therapy to control the rate of cystine precipitation and excretion,...
Approved
Investigational
Matched Description: … It is used after a failure of the non-pharmacological first line treatment consisting of increased fluid ... intake, restriction of sodium and protein, and urinary alkalinization. ... Tiopronin is a prescription thiol drug used primarily in the treatment of severe homozygous cystinuria …
Odevixibat
Odevixibat, or A4250, is an ileal sodium/bile acid cotransporter inhibitor indicated for the treatment of pruritus in patients older than 3 months, with progressive familial intrahepatic cholestasis (PFIC).[A236808,L34793] Odevixibat is the first approved non-surgical treatment option for PFIC. Previous therapies for PFIC included a bile acid sequestrant such as ursodeoxycholic...
Approved
Investigational
Matched Description: … Odevixibat, or A4250, is an ileal sodium/bile acid cotransporter inhibitor indicated for the treatment of …
Metronidazole
Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections.[A181036,A181039] Metronidazole has been used as an antibiotic for several decades , with added antiparasitic properties that set...
Approved
Matched Description: … Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. ... properties that set it apart from many other antibacterial drugs, allowing it to treat a wide variety of ... available in capsule form, tablet form, and topical form, and suppository preparations for the treatment of …
Matched Categories: … combinations of imidazole derivatives …
Matched Categories: … combinations of imidazole derivatives …
Tolmetin
A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.
Approved
Matched Description: … A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of …
Nitazoxanide
Nitazoxanide belongs to the class of drugs known as thiazolides. Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and microaerophilic bacteria, in addition to viruses. This drug is effective in the treatment of...
Approved
Investigational
Vet approved
Matched Description: … Nitazoxanide belongs to the class of drugs known as _thiazolides_. ... broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of ... a range of extracellular and intracellular protozoa, helminths, anaerobic and microaerophilic bacteria …
Resorcinol
Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders and infections such as acne, seborrheic dermatitis, eczema, psoriasis, corns, calluses, and warts. It exerts a keratolytic activity. Resorcinol works...
Approved
Matched Description: … Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. ... It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin ... possesses a well-documented anti-thyroidal activity that is generally not relied upon for any kind of …
Guaifenesin
Guaifenesin possesses a storied history, having been originally formally approved by the US FDA in 1952 and continues to be one of very few - if not perhaps the only drug that is readily available and used as an expectorant . Since that time the agent has been a combination...
Approved
Investigational
Vet approved
Matched Description: … guaifenesin in children under the age of 4 years was endorsed by FDA in 2008 [F4525]. ... storied history, having been originally formally approved by the US FDA in 1952 and continues to be one of ... Since that time the agent has been a combination component of various prescription and non-prescription …
Cetirizine
Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms , .
One of the most common uses for this drug is for a condition called allergic...
Approved
Matched Description: … One of the most common uses for this drug is for a condition called _allergic rhinitis_. ... Zyrtec_, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of ... The prevalence of allergic rhinitis in the United States is about 15% according to physician diagnoses …
Prussian blue
Prussian blue is described as a deep blue pigment that is produced when the oxidation of ferrous ferrocyanide salts occurs. It contains ferric hexacyanoferrate(II) in a cubic lattice crystal structure. It is insoluble in water but also tends to form a colloid thus can exist in either colloidal or water-soluble...
Approved
Matched Description: … metal poisoning, such as thallium and radioactive isotopes of caesium. ... Prussian blue is described as a deep blue pigment that is produced when the oxidation of ferrous ferrocyanide ... It is orally administered for clinical purposes to be used as an antidote for certain kinds of heavy …
Dextran
Dextran is a polysaccharide that differs from others in that its glucose units are joined together 1:6 glucoside links. The main chain of glucose has short branches at frequent intervals which are probably joined by 1:3 and 1:4 glucoside links. The chains can be composed of about 200,000 glucose units....
Approved
Investigational
Vet approved
Matched Description: … The chains can be composed of about 200,000 glucose units. ... The main chain of glucose has short branches at frequent intervals which are probably joined by 1:3 and ... [T121]
Dextran 40 is a sterile, nonpyrogenic preparation of low molecular weight dextran (average …
Ranolazine
Chronic angina is a common cardiovascular condition affecting millions worldwide and causes significant disability while interfering with daily activities. Ranolazine is a well-tolerated piperazine derivative used for the management of this condition, offering relief from uncomfortable and debilitating symptoms. With a mechanism of action different from drugs used to treat...
Approved
Investigational
Matched Description: … [A189234] Ranolazine is a well-tolerated piperazine derivative used for the management of this condition ... [L3580] With a mechanism of action different from drugs used to treat the same condition, ranolazine …
Avanafil
Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both sildenafil and vardenafil but less selectivity than tadalafil, suggesting a relatively lower risk of visual disturbances associated with...
Approved
Matched Description: … Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. ... In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than ... sildenafil] and [vardenafil] but less selectivity than [tadalafil], suggesting a relatively lower risk of …
Naloxegol
Naloxegol, for "PEGylated naloxol" is a peripherally-selective opioid antagonist developed by AstraZeneca. It was approved by the FDA in September 2014 and is indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non‑cancer pain. The advantage of naloxegol over the opioid antagonist naloxone is that its...
Approved
Matched Description: … The advantage of naloxegol over the opioid antagonist naloxone is that its PEGylated structure allows ... for high selectivity for peripheral opioid receptors and lack of entry into the central nervous system ... It was approved by the FDA in September 2014 and is indicated for the treatment of opioid-induced constipation …
Chromic nitrate
Approved
Chromium gluconate
Approved
Chromous sulfate
Approved
Clobetasol propionate
Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985.
Approved
Cefepime
Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics.[A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as Pseudomonas aeruginosa, and is also indicated...
Approved
Investigational
Matched Description: … of multidrug-resistant bacteria might be some of the factors leading to an increase in the use of cefepime ... microorganisms such as _Pseudomonas aeruginosa_, and is also indicated for the empirical treatment of ... The activity of cefepime against Enterobacteriaceae, _Pseudomonas aeruginosa_, and _Staphylococcus aureus …
Inositol nicotinate
Inositol nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ester and vasodilator. It is used in food supplements as a source of niacin (vitamin B3), where hydrolysis of 1 g (1.23 mmol) inositol hexanicotinate yields 0.91 g nicotinic acid and 0.22 g inositol. Niacin exists in...
Approved
Withdrawn
Matched Description: … It is used in food supplements as a source of niacin (vitamin B3), where hydrolysis of 1 g (1.23 mmol …
Displaying drugs 301 - 325 of 8039 in total