Displaying drugs 3226 - 3250 of 8252 in total
UCB7362
UCB7362 is an orally active plasmepsin X (PMX) inhibitor currently investigated for the treatment of malaria. Plasmepsins are aspartyl proteases produced by the malaria parasite Plasmodium falciparum, and PMX is considered to be essential for parasite egress and invasion. UCB7362 is estimated to achieve a significant reduction in asexual blood-stage...
Investigational
Matched Description: … dehydrogenase growth inhibition assay IC50 = 10 nM), and _in vivo_ (50 mg/kg dose in mice ... It has shown high potency in biochemical (IC50 = 7 nM), _in vitro_ (_P. falciparum_ 3D7 lactate …
RO7284755
RO7284755 is an investigational cancer drug: it is a PD-1-targeted IL-2 variant antibody fusion protein. RO7284755 is under investigation in clinical trial NCT04303858 (A Study to Evaluate Safety and Anti-tumor Activity of RO7284755 Alone or in Combination With Atezolizumab in Participants With Advanced And/or Metastatic Solid Tumors).
Investigational
Lixadesiran
Investigational
6,7-dioxo-5H-8-ribitylaminolumazine
Experimental
EHP-102
Investigational
Matched Synonyms: … 2-(3,7-Dimethyl-Octa-2, 6-Dienyl)-6-Ethylamino-3-Hydroxy-5-Pentyl-[1,4]Benzoquinone ... 2-(3,7-Dimethyl-octa-2, 6-dienyl)¿6-ethylamino-3-hydroxy-5-pentyl-[1,4]benzoquinone ... 2-((2e)-3,7-dimethyl-2,6-octadien-1-yl)-6-(ethylamino)-3-hydroxy-5-pentyl-2,5-cyclohexadiene-1,4-dione …
Matched Iupac: … 2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-6-(ethylamino)-3-hydroxy-5-pentylcyclohexa-2,5-diene-1,4-dione …
Matched Iupac: … 2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-6-(ethylamino)-3-hydroxy-5-pentylcyclohexa-2,5-diene-1,4-dione …
5,7-Dichlorokynurenic acid
Experimental
Sonlicromanol
Sonlicromanol is under investigation in clinical trial NCT04165239 (The KHENERGYZE Study).
Investigational
Matched Synonyms: … (S)-6-Hydroxy-2,5,7,8-Tetramethyl-N-((R)-Piperidin-3-Yl)Chroman-2-Carboxamide …
Irosustat
Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast Cancer.
Investigational
XomaZyme-791
Investigational
AMP-101
AMP-101 is a gene therapy comprising an adeno-associated virus type 9 (AAV9) vector encoding the human Dok-7 protein. It is under investigation for the treatment of Dok-7-associated myasthenia.
Investigational
Matched Description: … It is under investigation for the treatment of Dok-7-associated myasthenia. ... is a gene therapy comprising an adeno-associated virus type 9 (AAV9) vector encoding the human Dok-7 …
(R)-Gossypol
(R)-Gossypol is the R-isomer of Gossypol.
Investigational
Matched Synonyms: … (r)-2,2'-bis(8-formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene) ... Gossypol, r- ... Gossypol, (r)- …
Matched Name: … (R)-Gossypol …
Matched Description: … (R)-Gossypol is the R-isomer of [Gossypol]. …
Matched Name: … (R)-Gossypol …
Matched Description: … (R)-Gossypol is the R-isomer of [Gossypol]. …
Cefacetrile
A derivative of 7-aminocephalosporanic acid.
Experimental
Vet approved
Matched Iupac: … (6R,7R)-3-[(acetyloxy)methyl]-7-(2-cyanoacetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic …
Matched Description: … A derivative of 7-aminocephalosporanic acid. …
Matched Products: … CELOR ENTRAVENÖZ AMPUL 2G, 5 ADET …
Matched Description: … A derivative of 7-aminocephalosporanic acid. …
Matched Products: … CELOR ENTRAVENÖZ AMPUL 2G, 5 ADET …
SEL120-34A free base
Investigational
Matched Iupac: … 6,7-dibromo-5-methyl-2-(piperazin-1-yl)-1,3-diazatricyclo[6.3.1.0^{4,12}]dodeca-2,4,6,8(12)-tetraene …
Tricarbonyl(1,10-phenanthroline)rhenium(1+)
Experimental
Histidine
An essential amino acid that is required for the production of histamine.
Investigational
Nutraceutical
Matched Iupac: … (2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid …
Matched Mixtures name: … Aminosyn II 7% With 10% Dextrose ... Aminosyn II 7% M In 10% Dextrose(dual Chamber) ... Aminosyn 7% …
Matched Mixtures name: … Aminosyn II 7% With 10% Dextrose ... Aminosyn II 7% M In 10% Dextrose(dual Chamber) ... Aminosyn 7% …
Alanine
Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and the central nervous system.
Nutraceutical
Matched Mixtures name: … Aminosyn II 7% With 10% Dextrose ... Aminosyn II 7% M In 10% Dextrose(dual Chamber) ... Aminosyn 7% …
Methylcantharidimide
Methylcantharidimide is under investigation in clinical trial NCT03996681 (TACE Combined With Methylcantharidimide Tablets in the Treatment of Large and Unresectable Hepatocellular Carcinoma).
Investigational
Nemtabrutinib
Nemtabrutinib is under investigation in clinical trial NCT05624554 (A Study of Nemtabrutinib vs Chemoimmunotherapy for Participants With Previously Untreated Chronic Lymphocytic Leukemia/small Lymphocytic Lymphoma (CLL/SLL) Without TP53 Aberrations (MK-1026-008, BELLWAVE-008)).
Investigational
Matched Synonyms: … phenoxyphenyl)(4-(((3r,6s)-6-(hydroxymethyl)tetrahydro-2h-pyran-3-yl)amino)-7h-pyrrolo(2,3-d)pyrimidin-5- ... D-erythro-hexitol, 1,5-anhydro-2-((5-(2-chloro-4-phenoxybenzoyl)-7h-pyrrolo(2,3-d)pyrimidin-4-yl)amino ... 1,5-Anhydro-2-[[5-(2-chloro-4-phenoxybenzoyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-2,3,4-trideoxy-D-erythro-hexitol …
CT-001
Investigational
Displaying drugs 3226 - 3250 of 8252 in total