Displaying drugs 3301 - 3325 of 8249 in total
DTX-101
DTX-101 is an investigational gene therapy consisting of an adeno-associated virus serotype Rh10 vector encoding the human Factor Ix gene. It was previously investigated for the treatment of hemophilia B; however, the clinical development of DTX-101 was discontinued.
Investigational
RWJ-51084
Experimental
Matched Iupac: … N-[(2S)-1-(1,3-benzothiazol-2-yl)-5-[(diaminomethylidene)amino]-1-oxopentan-2-yl]cyclopentanecarboxamide …
6-Hydroxy-5-undecyl-4,7-benzothiazoledione
Experimental
Matched Synonyms: … 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole ... 6-Hydroxy-5-undecyl-4,7-benzothiazoledione ... 6-hydroxy-5-undecyl-1,3-benzothiazole-4,7-dione …
Matched Name: … 6-Hydroxy-5-undecyl-4,7-benzothiazoledione …
Matched Iupac: … 6-hydroxy-5-undecyl-4,7-dihydro-1,3-benzothiazole-4,7-dione …
Matched Name: … 6-Hydroxy-5-undecyl-4,7-benzothiazoledione …
Matched Iupac: … 6-hydroxy-5-undecyl-4,7-dihydro-1,3-benzothiazole-4,7-dione …
Castanospermine
Experimental
TIK-301
Investigational
Matched Synonyms: … (R)-N-[2-(6-Chloro-5-Methoxy-1H-Indol-3-Yl)Propyl]Acetamide ... N-((2r)-2-(6-chloro-5-methoxy-1h-indol-3-yl)propyl)acetamide …
Matched Iupac: … N-[(2R)-2-(6-chloro-5-methoxy-1H-indol-3-yl)propyl]acetamide …
Matched Iupac: … N-[(2R)-2-(6-chloro-5-methoxy-1H-indol-3-yl)propyl]acetamide …
Leucine
An essential branched-chain amino acid important for hemoglobin formation.
Investigational
Nutraceutical
Matched Mixtures name: … Aminosyn II 7% With 10% Dextrose ... Aminosyn II 7% M In 10% Dextrose(dual Chamber) ... Aminosyn 7% …
ONO-7579
Investigational
Matched Synonyms: … 1-[2-[4-(2-amino-5-chloropyridin-3-yl)phenoxy]pyrimidin-5-yl]-3-[2-methylsulfonyl-5-(trifluoromethyl) …
ORG-31710
ORG-31710 is a progestational hormone antagonist.
Experimental
Matched Iupac: … (1R,3aS,3bS,5R,10R,11aS)-10-[4-(dimethylamino)phenyl]-5,11a-dimethyl-2,3,3a,3b,4,5,7,8,9,10,11,11a-dodecahydrospiro ... [cyclopenta[a]phenanthrene-1,2'-oxolan]-7-one …
Afimetoran
Afimetoran is an immunomodulator and an antagonist of toll-like receptors 7 and 8.[L32018, L32023] It is also is under investigation in clinical trial NCT04269356 (Study to Assess the Way the Body Absorbs, Distributes, Breaks Down and Eliminates Radioactive BMS-986256 in Healthy Male Participants).
Investigational
Matched Iupac: … 2-[4-(2-{7,8-dimethyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl}-3-(propan-2-yl)-1H-indol-5-yl)piperidin-1-yl …
Matched Description: … Afimetoran is an immunomodulator and an antagonist of toll-like receptors 7 and 8. …
Matched Description: … Afimetoran is an immunomodulator and an antagonist of toll-like receptors 7 and 8. …
GTP-506
GTP-506 is a gene therapy formed by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and a therapeutic donor vector that inserts the OTC gene to provide the desired genetic correction.
Investigational
RO7502175
Investigational
CVN-424
CVN-424 is under investigation in clinical trial NCT06006247 (Early Parkinson's Disease Monotherapy With CVN424).
Investigational
ORC-13661
ORC-13661 is under investigation in clinical trial NCT05730283 (Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin).
Investigational
Matched Synonyms: … (1R,8S)-4-{[(4-chlorophenyl)carbamoyl]amino}-11-methyl-5-thia-11-azatricyclo[6.2.1.02,6]undeca ... (4R,6S)-2-[[[(4-Chlorophenyl)amino]carbonyl]amino]-4,5,6,7-tetrahydro-5-methyl-4,6-ethanothieno[3,2-c ... Ethanothieno[3,2-c]pyridine-3-carboxamide, 2-[[[(4-chlorophenyl)amino]carbonyl]amino]-4,5,6,7-tetrahydro-5- …
Recombinant Bacterial ACE2 Receptors-like Enzyme
B38-CAP is structured as a carboxypeptidase and derived from Paenibacillus sp. The molecule, an Angiotensin Converting Enzyme 2 (ACE2)-like enzyme, shares structural similarities to the mammalian ACE2. B38-CAP is an ACE2-like enzyme which decreases angiotensin II levels. It is being investigated for treating hypertension, myocardial fibrosis, and cardiac dysfunction.
Investigational
5-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine
Experimental
Matched Name: … 5-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine …
Matched Iupac: … 5-chloro-4-{1H,4H,5H,6H,7H-imidazo[4,5-c]pyridin-5-yl}-7H-pyrrolo[2,3-d]pyrimidine …
Matched Iupac: … 5-chloro-4-{1H,4H,5H,6H,7H-imidazo[4,5-c]pyridin-5-yl}-7H-pyrrolo[2,3-d]pyrimidine …
4,7-Dimethyl-[1,10]Phenanthroline
Experimental
RO-5045337
RO-5045337 is under investigation in clinical trial NCT01164033 (A Study of RO5045337 in Patients With Solid Tumors).
Investigational
Matched Iupac: … 1-[(4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazole …
RP-A501
RP-A501 is a gene therapy product consisting of a recombinant adeno-associated virus serotype 9 (rAAV9) capsid containing the human LAMP2B transgene (AAV9:LAMP2B), which encodes lysosome-associated membrane protein 2 (LAMP-2). It is being investigated for Danon disease.
Investigational
ADU-S100
ADU-S100 (MIW815) is a synthetic cyclic dinucleotide (CDN) agonist (activator) of Stimulator of Interferon Genes (STING), a receptor crucial to activate the innate (endogenous) immune system. ADU-S100 (MIW815) activates all known human and mouse STINGs, and effectively induces the expression of cytokines and chemokines, leading to a robust and durable...
Investigational
KTX-1001
Investigational
Matched Synonyms: … (S)-1-((R)-3-amino-1-(4-((6-amino-9H-purin-9-yl)methyl)-6-(2,5-difluoro-4-methoxyphenyl)pyridin-3-yl) …
SUVN-502
SUVN-502 is a novel, potent, safe, highly selective and orally active antagonist at a central nervous system serotonin receptor site 5-HT6 intended for treatment of cognitive disorders such as Alzheimer’s and Schizophrenia, an unmet medical need.
Investigational
Matched Iupac: … 1-(2-bromobenzenesulfonyl)-5-methoxy-3-[(4-methylpiperazin-1-yl)methyl]-1H-indole …
Matched Description: … , highly selective and orally active antagonist at a central nervous system serotonin receptor site 5- …
Matched Salts cas: … 1791396-46-7 …
Matched Description: … , highly selective and orally active antagonist at a central nervous system serotonin receptor site 5- …
Matched Salts cas: … 1791396-46-7 …
Flaviolin
Experimental
CPZEN-45
Investigational
Matched Synonyms: … Uridine, 5'-o-(5-amino-5-deoxy-.beta. ... 5-{[(5-amino-3,3-dihydroxyoxolan-2-yl)oxy][5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan ... -1h-1,4-diazepin-2-yl)-, (5's)- …
Matched Iupac: … (2S)-2-[(S)-{[(2S,3R,4S,5R)-5-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]oxy}[(2S,3S,4R,5R)-5-(2,4-dioxo- ... dihydroxyoxolan-2-yl]methyl]-N-(4-butylphenyl)-1,4-dimethyl-3-oxo-2,3,4,7-tetrahydro-1H-1,4-diazepine-5- …
Matched Iupac: … (2S)-2-[(S)-{[(2S,3R,4S,5R)-5-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]oxy}[(2S,3S,4R,5R)-5-(2,4-dioxo- ... dihydroxyoxolan-2-yl]methyl]-N-(4-butylphenyl)-1,4-dimethyl-3-oxo-2,3,4,7-tetrahydro-1H-1,4-diazepine-5- …
TG01 vaccine
Investigational
Matched Synonyms: … 12-A-p21 RAS(5-21). 12-C-p21 RAS(5-21). 12-D-p21 RAS(5-21). 12-Rp21 RAS(5-21). 12-S-p21 RAS(5-21). 12 ... -V-p21 RAS(5-21). 13-D-p21 RAS(5-21) …
Displaying drugs 3301 - 3325 of 8249 in total