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Displaying drugs 326 - 350 of 9223 in total

Etonogestrel

Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel. The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.
Approved
Investigational
Matched Iupac: … (1R,3aS,3bS,9aR,9bS,11aS)-11a-ethyl-1-ethynyl-1-hydroxy-10-methylidene-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H …
Matched Description: … molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Chlorothiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
Approved
Vet approved
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Categories: … combinations of sulfonamides …

Gestrinone

Gestrinone, also known as ethylnorgestrienone, is a synthetic steroid of the 19-nortestosterone group that is marketed in Europe, Australia, and Latin America, though not the United States or Canada, and is used primarily in the treatment of endometriosis. Gestrinone was developed in the early 1970s and was tested clinically as...
Approved
Matched Description: … Gestrinone, also known as ethylnorgestrienone, is a synthetic steroid of the 19-nortestosterone group ... , and Latin America, though not the United States or Canada, and is used primarily in the treatment of …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Phenoxymethylpenicillin

Phenoxymethylpenicillin is a narrow spectrum antibiotic also commonly referred to as Penicillin V or Penicillin VK. It is a phenoxymethyl analog of Penicillin G, or benzylpenicillin. An orally active naturally penicillin, phenoxymethylpenicillin is used to treat mild to moderate infections in the respiratory tract, skin, and soft tissues caused by...
Approved
Vet approved
Matched Description: … [A178609] It is a phenoxymethyl analog of Penicillin G, or [benzylpenicillin]. ... or other acquired valvular heart disease when they undergo dental procedures and surgical procedures of …
Matched Categories: … combinations of penicillins …

Nimodipine

Nimodipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Compared to other calcium channel blocking...
Approved
Investigational
Matched Description: … By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth …
Matched Products: … NIMODIPINO 10 MG/50 ML ... Nimotop 10 mg - Infusionsflasche ... NIMODIPINO 10 MG / 50 ML …

Bexagliflozin

Bexagliflozin is a highly specific and potent sodium-glucose co-transporter 2 (SGLT2) inhibitor.[A256408,A256413,L44758] Similar to other SGLT2 inhibitors, bexagliflozin contains three basic moieties: glucose, two benzene rings and a methylene bridge. SGLT2 is responsible for 60% to 90% of renal glucose re-uptake, and unlike other isoforms such as SGLT1, SGLT2 is...
Approved
Investigational
Matched Description: … urinary glucose excretion, which reduces blood glucose levels independently of insulin sensitivity. ... [A256413] SGLT2 is responsible for 60% to 90% of renal glucose re-uptake, and unlike other isoforms such ... [A256408] By inhibiting SGLT2, bexagliflozin reduces renal reabsorption of filtered glucose and increases …

Ergocalciferol

Ergocalciferol is an inactivated vitamin D analog. It is synthesized by some plants in the presence of UVB light. The production of ergocalciferol was prompted by the identification of dietary deficiency, more specifically vitamin D, as the main causative factor for the development of rickets. Ergocalciferol was isolated for the...
Approved
Nutraceutical
Matched Iupac: … (1S,3Z)-3-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden- …
Matched Description: … [T577] The production of ergocalciferol was prompted by the identification of dietary deficiency, more ... [A177526] It is synthesized by some plants in the presence of UVB light. ... a double bond between C22 and C23 and the presence of a methyl group at C24. …
Matched Mixtures name: … Maxi 10 Tab ... VITALIPID N-ADULT 10 AMPUL ... VITALIPID N-INFANT 10 AMPUL …

Etilefrine

Etilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors. It has been used as a vasoconstrictor agent.
Approved
Withdrawn
Matched Products: … ETILEFRINACLORHIDRATO 10 MG /ML ... ETILEFRINA CLORHIDRATO 10 MG/ ML …

Manidipine

Manidipine (INN) is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive. It is selective for vasculature and does not produce effects on the heart at clinically relevant dosages.
Approved
Investigational
Matched Products: … มาดิพลอต 10 มก. ... นิคพี-มานิดิปีน เม็ด 10 มก …

Diflunisal

Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the...
Approved
Investigational
Matched Description: … Though its mechanism of action has not been clearly established, most of its actions appear to be associated ... with inhibition of prostaglandin synthesis via the arachidonic acid pathway. ... Diflunisal is used to relieve pain accompanied with inflammation and in the symptomatic treatment of …
Matched Products: … DOLPHIN 250 MG FILM TABLET, 10 TABLET ... DOLPHIN 500 MG FILM TABLET, 10 TABLET …

Insulin aspart

Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … high levels of insulin in a short period of time to mimic the release of endogenous insulin from the ... , with a goal of avoiding any periods of hypoglycemia. ... Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type …
Matched Mixtures name: … RYZODEG PENFİLL 100 U/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KARTUŞ, 10 ADET ... RYZODEG FLEXTOUCH 100 U/ML ENJEKSİYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 10 ADET …
Matched Products: … FİASP® PENFİLL® 100 U/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KARTUŞ, 10 ADET ... FİASP® FLEXTOUCH® 100 U/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 10 ADET …

Chlordiazepoxide

An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
Approved
Illicit
Investigational
Matched Description: … It has also been used in the symptomatic treatment of alcohol withdrawal. …
Matched Products: … BENPINE CAPSULE 10 mg ... Medilium Cap 10 10mg …

Regadenoson

Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Approved
Investigational
Matched Description: … Manufactured by Astellas and FDA approved April 10, 2008. …

Rilonacept

Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein linked to the Fc portion of immunoglobulin G1. Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome...
Approved
Investigational
Matched Description: … Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein ... linked to the Fc portion of immunoglobulin G1. ... Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as …

Amikacin

Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Description: … of breath and the coughing up of blood. ... the deoxystreptamine moiety of kanamycin A. ... of patients with the disease who do not respond to traditional treatment. …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ, 10 ADET ... ENJEKSİYONLUK ÇÖZELTİ, 10 ADET ... ENJEKSİYONLUK ÇÖZELTİ, 10 ADET …

Cedazuridine

Myelodysplastic syndromes (MDS) are a group of hematopoietic neoplasms that give rise to variable cytopenias progressing to secondary acute myeloid leukemia (sAML), which is invariably fatal if untreated.[A215082, A215092, A215097] Hypomethylating agents such as decitabine and azacitidine are used to treat MDS through inducing DNA hypomethylation and apoptosis of cancerous...
Approved
Investigational
Matched Description: … Myelodysplastic syndromes (MDS) are a group of hematopoietic neoplasms that give rise to variable cytopenias ... decitabine] and [azacitidine] are used to treat MDS through inducing DNA hypomethylation and apoptosis of ... tetrahydrouridine derivative specifically designed to inhibit CDA and facilitate oral administration of …

Becaplermin

Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae. Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together...
Approved
Investigational
Matched Description: … Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet ... Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …

Ombitasvir

Ombitasvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Description: … class of DAAs [A19593]. ... The barrier for develoment of resistance to NS5A inhibitors is lower than that of NS5B inhibitors, another ... Lack of significant side effects and short duration of therapy is a considerable advantage over older …
Matched Categories: … Antivirals for treatment of HCV infections …

Estetrol

Naturally or synthetically produced steroid estrogens have a wide range of pharmaceutical uses ranging from hormonal contraception to the treatment of menopausal symptoms. Estetrol (E4) is a native estrogen occurring naturally during pregnancy, but can be synthesized from a plant source and used for contraception. It is more potent and...
Approved
Investigational
Matched Description: … from hormonal contraception to the treatment of menopausal symptoms. ... Naturally or synthetically produced steroid estrogens have a wide range of pharmaceutical uses ranging ... L33179] It is more potent and is safer than the synthetic estrogen ethinylestradiol (EE2) found in 97% of …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Butorphanol

A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Approved
Illicit
Vet approved
Matched Description: … It is used in the management of severe pain. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Ulobetasol

Ulobetasol is a highly potent corticosteroid. It is structurally related to clobetasol. Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.[L15047,L15052,L15102] Ulobetasol was granted FDA approval on 17 December 1990.
Approved
Matched Synonyms: … 21-chloro diflorasone …
Matched Description: … [A215597] Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis …

Albendazole

A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Approved
Vet approved
Matched Products: … ALBAZOL 10% Oral Suspension ... ALBENDEX 10 % w/v Oral suspension ... ZENTEL SUSPENSION 400 mg/10 ml …

Calcitriol

Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D3, 1,25-dihydroxyvitamin D3. It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to DB00169 (vitamin D3)...
Approved
Nutraceutical
Matched Description: … It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to ... Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred ... Calcitriol is considered to be the most potent metabolite of vitamin D in humans [A3366]. …

Alogliptin

Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.
Approved
Matched Description: … Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase …

Ezogabine

Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine. It is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 trials as an adjunctive treatment for partial-onset seizures in adult patients with refractory epilepsy....
Approved
Investigational
Matched Description: … FDA approved in June 10, 2011 under the name of ezogabine. ... Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine. …
Displaying drugs 326 - 350 of 9223 in total