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Displaying drugs 326 - 350 of 10517 in total

Loxapine

An antipsychotic agent used in schizophrenia. [PubChem]
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Metolazone

A quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
Approved
Matched Categories: … combinations of sulfonamides …

Minaprine

Minaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive states. Like most antidepressants minaprine antagonizes behavioral despair. Minaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and weight gain.
Approved
Matched Description: … Minaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive ... Minaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Opium

Opium is the first substance of the diverse group of the opiates. It has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years by the Sumerians. During the years, opium was used as a sedative and hypnotic, but it was...
Approved
Illicit
Matched Description: … Opium is the first substance of the diverse group of the opiates. ... harmful effects of opium. ... in the category of isoquinolines. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Clavulanic acid

Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with Amoxicillin or Ticarcillin to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infections. Clavulanic acid is derived from the organism Streptomyces clavuligerus. When it is combined with amoxicillin, clavulanic acid is...
Approved
Vet approved
Matched Description: … antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of …
Matched Mixtures name: … AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/S ... AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/S ... AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/S …

Smelt

Smelt allergenic extract is used in allergenic testing.
Approved

Thrombin

Also known as coagulation factor II, thrombin is a serine protease that plays a physiological role in regulating hemostasis and maintaining blood coagulation. Once converted from prothrombin, thrombin converts fibrinogen to fibrin, which, in combination with platelets from the blood, forms a clot. Medical thrombin is a protein substance produced...
Approved
Investigational
Matched Description: … It clots the fibrinogen of the blood directly. ... bovine origin is activated by tissue thromboplastin in the presence of calcium chloride. ... Bleeding may result from the development of antibodies against bovine factor V [FDA Label]. …
Matched Mixtures name: … TISSEEL FIBRIN SEALANT VH S/D (FROZEN) …

Ethylhexyl methoxycrylene

Ethylhexyl methoxycrylene is a photostabilizer that preserves the effectiveness of UV filters by interacting with both the singlet and triplet states . It returns UV filters to their ground states without absorbing sunlight . It is used as a solvent for crystalline UV filters and is easily emulsified and suitable...
Approved
Experimental
Matched Description: … Ethylhexyl methoxycrylene is a photostabilizer that preserves the effectiveness of UV filters by interacting …

Capsaicin

Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. The most recent...
Approved
Matched Description: … Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, ... and patch preparations of various strengths; however, it may also be found in some dietary supplements …
Matched Mixtures name: … s Cream …
Matched Products: … Nufabrx Lower Leg Sleeve XS/S …

Squash

Squash allergenic extract is used in allergenic testing.
Approved

Hydrocortisone acetate

Approved
Vet approved
Matched Mixtures name: … Coly-Mycin S ... Coly-Mycin S ... Coly-Mycin S …

Isoniazid

Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Approved
Investigational
Matched Description: … It remains the treatment of choice for tuberculosis. …
Matched Mixtures name: … DOTBAL-S …
Matched Categories: … Drugs for Treatment of Tuberculosis ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Fluvoxamine

Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder. Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised...
Approved
Investigational
Matched Description: … As of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine. ... Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised of …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Trimipramine

Tricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
Approved
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Lopinavir

Lopinavir is an antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 infection. Lopinavir is marketed and administered exclusively in combination with ritonavir - this combination, first marketed by Abbott under the brand name Kaletra in 2000, is necessary due to lopinavir's poor oral bioavailability...
Approved
Matched Description: … an antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of ... targeted by the HIV-1 protease enzyme but which itself cannot be cleaved, thus preventing the activity of ... Ritonavir is a potent inhibitor of the enzymes responsible for lopinavir metabolism, and its co-administration …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Antivirals used in combination for the treatment of HIV infections …

Polyethylene glycol 400

Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions. Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations. PEGs, along with their many nonionic derivatives, are...
Approved
Matched Description: … dryness of the eye [L1785]. ... Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain ... Examples of PEGylated medications are PEG-interferon alpha (Pegintron) and PEG-filgrastim. …

Phentermine

Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug.[A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine. Phentermine has not been reported an addictive potential which allows this agent to...
Approved
Illicit
Matched Description: … ] was discontinued after finding several reports of abnormal valves in nearly 30% of the consumers. ... Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity ... This initial product, formed by the combination of phentermine with [fenfluramine] and [dexfenfluramine …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Buspirone

Buspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. Belonging to the azaspirodecanedione drug class, buspirone is a serotonin 5-HT1A receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates, and other sedative/anxiolytic drugs. Unlike many drugs used to treat anxiety, buspirone does...
Approved
Investigational
Matched Description: … been used to treat anxiety disorders, such as generalized anxiety disorder (GAD), and relieve symptoms of ... It has also been used as a second-line therapy for unipolar depression when the use of selective serotonin ... [L7375] The potential use of buspirone in combination with [melatonin] in depression and cognitive impairment …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Thiopental

A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure. It does not...
Approved
Vet approved
Matched Description: … of complete anesthesia of short duration. ... It is also used for hypnosis and for the control of convulsive states. ... A barbiturate that is administered intravenously for the induction of general anesthesia or for the production …
Matched Categories: … combinations of barbiturates …

Cyclobenzaprine

Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond.[A185039,A184982] Since its approval, it has...
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Drospirenone

Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with Ethinyl estradiol. Most recently, it was approved by both Health Canada and the FDA in combination with Estetrol as an oral contraceptive therapy.[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to...
Approved
Matched Description: … Drospirenone has been the subject of widespread safety concern due to the possibility of an increased ... risk of venous thromboembolism associated with its use. ... thromboembolism resulting from the use of drospirenone remains unclear, as studies regarding this risk …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Sertindole

Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. Serdolect is developed by the Danish pharmaceutical company H. Lundbeck. It is a phenylindole derivative used in the treatment of schizophrenia. It was first marketed in 1996 in several European countries before being withdrawn two years later because of...
Approved
Investigational
Withdrawn
Matched Description: … It is a phenylindole derivative used in the treatment of schizophrenia. ... Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. ... first marketed in 1996 in several European countries before being withdrawn two years later because of …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Pizotifen

Pizotifen belongs to the class of antamines and is related to cyproheptadine. It is a potent serotonin and tryptamine antagonist that has been used for migraine prevention for many years. It exhibits weak anticholinergic, antihistamine, and antikinin actions in addition to sedative and appetite-stimulating properties . Some patients receiving pizotifen...
Approved
Matched Description: … of its antimigraine action [A32538]. ... Pizotifen belongs to the class of antamines and is related to [cyproheptadine]. ... Sandomigran is available in a number of countries but is not approved by the FDA nor EMA. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Sotalol

Sotalol is a methanesulfonanilide developed in 1960. It was the first of the class III anti arrhythmic drugs. Sotalol was first approved as an oral tablet on 30 October 1992. A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous injection indicated for life threatening...
Approved
Matched Description: … [A178579] It was the first of the class III anti arrhythmic drugs. ... [L6334] A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous …

Sucrose

A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. It is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a food and a sweetener.
Approved
Experimental
Investigational
Matched Description: … A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. …
Displaying drugs 326 - 350 of 10517 in total