Displaying drugs 3626 - 3650 of 4265 in total
Sotatercept
Sotatercept is an activin signalling inhibitor. It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension...
Approved
Investigational
Matched Synonyms: … (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... HEAVY CONSTANT .GAMMA.1 FC FRAGMENT: (8-15)-HINGE-(A-100>V)-CH2-CH3 OF HOMO SAPIENS IGHG1*03), (123-123 ... (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... [L50351] On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... [L50351] On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tozuleristide
Tozuleristide is under investigation in clinical trial NCT02464332 (Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery).
Investigational
Matched Synonyms: … ,23-ARGININE(K>R))CHLOROTOXIN (CTX, CLTX) LEIURUS QUINQUESTRIATUS QUINQUESTRI ... YL)HEPTA-2,4,6-TRIENYLIDENE)-1,1-DIMETHYL-1,2-DIHYDRO-3H-BENZO(E)INDOL-3-YL)HEXANOYL)(15-ARGININE(K>R) …
Ebvaciclib
Ebvaciclib is under investigation in clinical trial NCT03519178 (A Study of PF-06873600 in People With Cancer).
Investigational
Matched Synonyms: … )pyrido(2,3-d)pyrimidin-7(8h)-one ... Pyrido(2,3-d)pyrimidin-7(8h)-one, 6-(difluoromethyl)-8-((1r,2r)-2-hydroxy-2-methylcyclopentyl)-2-((1- ... 6-(difluoromethyl)-8-((1r,2r)-2-hydroxy-2-methylcyclopentyl)-2-((1- (methylsulfonyl)piperidin-4-yl) amino …
Cinchonidine
Investigational
Matched Synonyms: … Alpha-quinidine …
Matched Iupac: … (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](quinolin-4-yl)methanol …
Matched Iupac: … (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](quinolin-4-yl)methanol …
Medazepam
Experimental
Matched Mixtures name: … TRANKO-BUSKAS 10 MG + 10 MG KAPLI TABLET, 20 ADET …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives ... Hypnotics and Sedatives …
Matched Products: … NOBRAL 10 MG KAPSÜL, 20 ADET …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives ... Hypnotics and Sedatives …
Matched Products: … NOBRAL 10 MG KAPSÜL, 20 ADET …
Tizanidine
Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury . It may also be caused by musculoskeletal injury . Regardless of the cause, muscle spasticity can be an...
Approved
Investigational
Matched Description: … Regardless of the cause, muscle spasticity can be an extremely painful and debilitating condition. ... Initially approved by the FDA in 1996, tizanidine is an Alpha-2 adrenergic receptor agonist reducing …
Matched Salts cas: … 64461-82-1 …
Matched Categories: … Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
Matched Products: … CIMBRAR(R) SR CAPSULA DE LIBERACIÓN PROGRAMADA …
Matched Salts cas: … 64461-82-1 …
Matched Categories: … Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
Matched Products: … CIMBRAR(R) SR CAPSULA DE LIBERACIÓN PROGRAMADA …
C-(1-Azido-Alpha-D-Glucopyranosyl) Formamide
Experimental
Matched Name: … C-(1-Azido-Alpha-D-Glucopyranosyl) Formamide …
Edotreotide gallium Ga-68
Edotreotide gallium Ga-68 is an 8 amino acid peptide bound to the chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA). Edotreotide gallium Ga-68 is indicated for localizing somatostatin receptor positive neuroendocrine tumors by positron emission tomography. Dotatate gallium Ga-68 is used for a similar indication. Dotatate gallium Ga-68 has lower tumor uptake but this...
Approved
Matched Description: … Edotreotide gallium Ga-68 is an 8 amino acid peptide bound to the chelator 1,4,7,10-tetraazacyclododecane ... -1,4,7,10-tetraacetic acid (DOTA). ... [A185852]
Edotreotide gallium Ga-68 was granted FDA approval on 21 August 2019.[L8597] …
Matched Products: … Sogacin 20 MBq/ml Injektionslösung …
Matched Products: … Sogacin 20 MBq/ml Injektionslösung …
Glimepiride
First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive...
Approved
Matched Description: … of the beta cells. ... sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic ... long-term microvascular and macrovascular complications that lead to co-morbidities and mortalities. …
Matched Mixtures name: … Pioglitazone and Glimepiride ... Pioglitazone and Glimepiride ... Pioglitazone hydrochloride and glimepiride …
Matched Categories: … Alimentary Tract and Metabolism ... glimepiride and rosiglitazone ... glimepiride and pioglitazone …
Matched Products: … GLIMEPIRIDE SANDOZ(R) (2 MG) ... TIDECA 8 MG TABLET, 30 TABLET ... TIDECA 8 MG TABLET, TABLET, 90 ADET …
Matched Mixtures name: … Pioglitazone and Glimepiride ... Pioglitazone and Glimepiride ... Pioglitazone hydrochloride and glimepiride …
Matched Categories: … Alimentary Tract and Metabolism ... glimepiride and rosiglitazone ... glimepiride and pioglitazone …
Matched Products: … GLIMEPIRIDE SANDOZ(R) (2 MG) ... TIDECA 8 MG TABLET, 30 TABLET ... TIDECA 8 MG TABLET, TABLET, 90 ADET …
Bambuterol
Bambuterol is a long acting beta-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline.
Investigational
Matched Description: … Bambuterol is a long acting beta-adrenoceptor agonist used in the treatment of asthma. …
Matched Categories: … Alcohols ... Amino Alcohols ... Adrenergic beta-Agonists ... Adrenergic beta-2 Receptor Agonists ... Selective Beta 2-adrenergic Agonists …
Matched Products: … BAMBEC ® TABLETAS 20 MG …
Matched Categories: … Alcohols ... Amino Alcohols ... Adrenergic beta-Agonists ... Adrenergic beta-2 Receptor Agonists ... Selective Beta 2-adrenergic Agonists …
Matched Products: … BAMBEC ® TABLETAS 20 MG …
Lomitapide
Lomitapide is a microsomal triglyceride transfer protein (MTP) inhibitor used in homozygous familial hypercholesterolemia (HoFH) patients. It is marketed under the name Juxtapid (R).
Approved
Investigational
Matched Description: … It is marketed under the name Juxtapid (R). …
Matched Salts cas: … 202914-84-9 …
Matched Products: … JUXTAPID® CÁPSULAS POR 20 MG …
Matched Salts cas: … 202914-84-9 …
Matched Products: … JUXTAPID® CÁPSULAS POR 20 MG …
Leukotriene C4
The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular smooth muscle. (From Dictionary of Prostaglandins and...
Experimental
Investigational
Matched Synonyms: … (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl …
Matched Iupac: … -carboxybutanamido]-2-[(carboxymethyl)carbamoyl]ethyl]sulfanyl}-5-hydroxyicosa-7,9,11,14-tetraenoic acid …
Matched Description: … It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized ... The conjugation product of LEUKOTRIENE A4 and glutathione. ... It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular …
Matched Categories: … Arachidonic Acids ... Fatty Acids ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
Matched Iupac: … -carboxybutanamido]-2-[(carboxymethyl)carbamoyl]ethyl]sulfanyl}-5-hydroxyicosa-7,9,11,14-tetraenoic acid …
Matched Description: … It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized ... The conjugation product of LEUKOTRIENE A4 and glutathione. ... It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular …
Matched Categories: … Arachidonic Acids ... Fatty Acids ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
Inosine pranobex
Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol used as an antiviral drug.
Approved
Matched Iupac: … tris((2R)-1-(dimethylamino)propan-2-ol); tris(4-acetamidobenzoic acid); 9-[(2R,3R,4S,5R)-3,4-dihydroxy …
Matched Description: … and dimethylaminoisopropanol used as an antiviral drug. ... Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … VELP 500 MG TABLET, 20 ADET ... İNOBEKS 500 MG TABLET, 20 ADET …
Matched Description: … and dimethylaminoisopropanol used as an antiviral drug. ... Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … VELP 500 MG TABLET, 20 ADET ... İNOBEKS 500 MG TABLET, 20 ADET …
N-(2-Aminoethyl)-5-Chloroisoquinoline-8-Sulfonamide
Experimental
Matched Name: … N-(2-Aminoethyl)-5-Chloroisoquinoline-8-Sulfonamide …
Matched Iupac: … N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide …
Matched Iupac: … N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide …
8-(Pyrimidin-2-Ylamino)Naphthalene-2-Carboximidamide
Experimental
Matched Name: … 8-(Pyrimidin-2-Ylamino)Naphthalene-2-Carboximidamide …
Matched Iupac: … 8-[(pyrimidin-2-yl)amino]naphthalene-2-carboximidamide …
Matched Iupac: … 8-[(pyrimidin-2-yl)amino]naphthalene-2-carboximidamide …
(9S)-9-[(8-AMMONIOOCTYL)AMINO]-1,2,3,4,9,10-HEXAHYDROACRIDINIUM
Experimental
Matched Name: … (9S)-9-[(8-AMMONIOOCTYL)AMINO]-1,2,3,4,9,10-HEXAHYDROACRIDINIUM …
Matched Iupac: … 9-[(8-azaniumyloctyl)amino]-1,2,3,4-tetrahydroacridin-10-ium …
Matched Iupac: … 9-[(8-azaniumyloctyl)amino]-1,2,3,4-tetrahydroacridin-10-ium …
Solnatide
Solnatide has been used in trials studying the treatment of Acute Lung Injury.
Investigational
Matched Synonyms: … L-Cysteine, L-cysteinylglycyl-L-glutaminyl-L-arginyl-L-alpha-glutamyl-L-threonyl-L-prolyl-L-alpha-glutamylglycyl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-lysyl-L-prolyl-L-tryptophyl-L-tyrosyl …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Gadopiclenol
Gadopiclenol is a gadolinium-based contrast agent (GBCA) based on a pyclen macrocyclic structure. It is indicated for use with magnetic resonance imaging (MRI) to detect and visualize lesions with abnormal vascularity in the central nervous system and the body. In 2006, the use of GBCAs was associated with the development...
Approved
Matched Synonyms: … (.alpha.3,.alpha.6,.alpha.9-tris(3-((2,3-dihydroxypropyl)amino)-3-oxopropyl)-3,6,9,15-tetraazabicyclo …
Matched Description: … [A254002] Gadopiclenol has high kinetic stability and a high r1 relaxivity, allowing it to be used at ... vascularity in the central nervous system and the body. ... (NSF), a rare disorder characterized by the thickening and hardening of skin and subcutaneous tissues …
Matched Description: … [A254002] Gadopiclenol has high kinetic stability and a high r1 relaxivity, allowing it to be used at ... vascularity in the central nervous system and the body. ... (NSF), a rare disorder characterized by the thickening and hardening of skin and subcutaneous tissues …
AVR-48
Investigational
Matched Synonyms: … 4-nitrophenyl-n-acetyl-beta-d-glucosaminide ... 4-nitrophenyl 2-acetamido-2-deoxy-beta-d-glucopyranoside ... .beta.-d-glucopyranoside, 4-nitrophenyl 2-(acetylamino)-2-deoxy- …
Fluorouracil
A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.
Approved
Matched Description: … to thymidylic acid. ... It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Antineoplastic and Immunomodulating Agents ... Fluorouracil and prodrugs ... Skin and Mucous Membrane Agents …
Matched Products: … EFUDIX %5 KREM , 20 G ... FLUOROURACIL AC1000MG/20ML ... FLUOROURACILO 500 MG/20 ML …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Antineoplastic and Immunomodulating Agents ... Fluorouracil and prodrugs ... Skin and Mucous Membrane Agents …
Matched Products: … EFUDIX %5 KREM , 20 G ... FLUOROURACIL AC1000MG/20ML ... FLUOROURACILO 500 MG/20 ML …
Etoricoxib
Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic...
Approved
Investigational
Matched Description: … of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and ... of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic acid …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … ETORICOXIB BETA 30MG ... ETORICOXIB BETA 60MG ... ETORICOXIB BETA 90MG …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … ETORICOXIB BETA 30MG ... ETORICOXIB BETA 60MG ... ETORICOXIB BETA 90MG …
7-Alpha-D-Ribofuranosyl-Purine-5'-Phosphate
Experimental
Matched Name: … 7-Alpha-D-Ribofuranosyl-Purine-5'-Phosphate …
Matched Iupac: … {[(2R,3S,4R,5S)-3,4-dihydroxy-5-(7H-purin-7-yl)oxolan-2-yl]methoxy}phosphonic acid …
Matched Iupac: … {[(2R,3S,4R,5S)-3,4-dihydroxy-5-(7H-purin-7-yl)oxolan-2-yl]methoxy}phosphonic acid …
N-alpha-Acetyl-3,5-diiodotyrosyl-D-threonine
Experimental
Matched Name: … N-alpha-Acetyl-3,5-diiodotyrosyl-D-threonine …
Matched Iupac: … (2R,3R)-2-[(2S)-2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanamido]-3-hydroxybutanoic acid …
Matched Iupac: … (2R,3R)-2-[(2S)-2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanamido]-3-hydroxybutanoic acid …
Alpha-D-Glucose-1-Phosphate-6-Vanadate
Experimental
Matched Name: … Alpha-D-Glucose-1-Phosphate-6-Vanadate …
Olpasiran
Olpasiran is under investigation in clinical trial NCT05581303 (Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (Ocean(a)) - Outcomes Trial).
Investigational
Matched Synonyms: … ALL-P-AMBO-5'-O-((25S,30S)-39-((2-ACETAMIDO-2-DEOXY-.BETA. ... -D-GALACTOPYRANOSYL)OXY)-25,30-BIS((2-(2-((2-ACETAMIDO-2-DEOXY-.BETA. …
Matched Description: … Olpasiran is under investigation in clinical trial NCT05581303 (Olpasiran Trials of Cardiovascular Events and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleic Acids ... RNA, Antisense ... RNA, Untranslated ... RNA, Small Untranslated …
Matched Description: … Olpasiran is under investigation in clinical trial NCT05581303 (Olpasiran Trials of Cardiovascular Events and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleic Acids ... RNA, Antisense ... RNA, Untranslated ... RNA, Small Untranslated …
Displaying drugs 3626 - 3650 of 4265 in total