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Displaying drugs 351 - 375 of 15219 in total

Trandolapril

Trandolapril is a non-sulhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to its biologically active diacid form, trandolaprilat, in the liver. Trandolaprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure...
Approved
Matched Iupac: … (2S,3aR,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydro-1H-indole- …
Matched Description: … Trandolapril is a non-sulhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... It is metabolized to its biologically active diacid form, trandolaprilat, in the liver. …
Matched Mixtures name: … TARKA® SR240/4 TABLETAS. ... VERACOMB MR 240/4 MG KAPSÜL, 28 ADET ... TARKA FORTE 240/4 FILM TABLET, 28 ADET …
Matched Products: … GOPTEN FORTE 4 MG KAPSUL, 28 ADET …

Remdesivir

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which is a respiratory disease that is capable of progressing to viral pneumonia and acute respiratory distress syndrome (ARDS); COVID-19 can be fatal. Like other RNA viruses, SARS-CoV-2 depends on an RNA-dependent RNA polymerase...
Approved
Investigational
Matched Iupac: … 2-ethylbutyl (2S)-2-{[(S)-{[(2R,3S,4R,5R)-5-{4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl}-5-cyano-3,4-dihydroxyoxolan …
Matched Description: … in 2016 as a potential treatment for Ebola. ... ] leading to considerable interest in remdesivir as a possible treatment for COVID-19. ... a class of drugs known as nucleoside analogues. …

Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen

Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational
Matched Description: … booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus ... strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a ... vaccine contains Haemophilus b capsular polysaccharide (polyribosyl-ribitol-phosphate [PRP]), which is a …

Nitrofurantoin

Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. This drug is more resistant to the development of bacterial resistance because it acts...
Approved
Vet approved
Matched Description: … [L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates ... Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections. ... [A179824] Nitrofurantoin is a second line treatment to [trimethoprim]/[sulfamethoxazole]. …
Matched Products: … NEO FURADANTIN …

Phylloquinone

Vitamin K1, also called phylloquinone or phytonadione, is a fat soluble vitamin.[L33319,L33345] Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates precursors to coagulation factors II, VII, IX, and X.[A234264,A234195,A234259] It is indicated in the treatment of coagulation disorders due to faulty formation of coagulation factors II,...
Approved
Investigational
Matched Description: … of coagulation factors II, VII, IX, and X caused by deficiency or interference in the activity of vitamin ... Vitamin K1, also called phylloquinone or phytonadione, is a fat soluble vitamin. ... [L33319,L33345] Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates …
Matched Mixtures name: … Mvc 9+4 Inj …
Matched Products: … NEO-K …

Denosumab

Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption via inhibiting RANK-mediated activation of osteoclasts. It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss. Chemically, it consists of 2 heavy...
Approved
Matched Description: … Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear ... each light chain consisting of 215 amino acids and each heavy chain consisting of 448 amino acids with 4 ... [A263066] Denosumab was approved by the FDA approved on June 2010 for the treatment of osteoporosis …
Matched Products: … ENJEKSIYONLUK COZELTI ICEREN FLAKON, 4 ADET …

Chymopapain

Chymopapain was first isolated in 1941 from the crude latex derived from the fruit of Carica papaya by squeezing the green papaya while on the plant prior to harvest. It is an extracellular plant cysteine proteinase similar to papain in specificity. Chymopapain was developed by Chart Medcl and FDA approved...
Approved
Withdrawn
Matched Description: … Chymopapain was first isolated in 1941 from the crude latex derived from the fruit of Carica papaya by ... [L2482]It is an extracellular plant cysteine proteinase similar to papain in specificity. ... [A32688] Chymopapain was developed by Chart Medcl and FDA approved on November 10, 1982. …
Matched Products: … Chymodiactin Injection - 4 Nkat Units/2ml …

Elranatamab

Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb, each of which contributes one heavy chain and one light chain to drug structure. The resulting 4-chain bispecific...
Approved
Investigational
Matched Synonyms: … ANTI-(HOMO SAPIENS T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN CD3E (T-CELL SURFACE ANTIGEN T3/LEU-4 …
Matched Description: … [L47820] Elranatamab was also approved by the European Commission on December 8, 2023.[L50437] ... The resulting 4-chain bispecific antibody is covalently linked via five inter-chain disulfide bonds. ... Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. …

Gadobenic acid

Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of the liver. It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity....
Approved
Investigational
Matched Iupac: … gadolinium(3+) ion 4-carboxy-8,11-bis(carboxylatomethyl)-5-(carboxymethyl)-1-phenyl-2-oxa-5,8,11-triazatridecan …
Matched Description: … Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based ... [A1139] Gadobenate dimeglumine was approved by the FDA in November 2004 under the brand name MultiHance ... biliary system, it is a useful contrast agent for liver MRI. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … MultiHance 0,5 mmol/ml Injektionslösung in einer Fertigspritze …

Thonzylamine

Thonzylamine is an antihistamine and anticholinergic drug. It is available as combination products with DB04837 or DB00388 for temporary relief of symptoms of common cold, hay fever (allergic rhinitis) or other upper respiratory allergies.
Approved
Matched Iupac: … N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyrimidin-2-amine …

Crotamiton

Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only. It is a colorless to slightly yellowish oil, having a faint amine-like odor. It is miscible with alcohol and with methanol.
Approved
Matched Description: … It is a colorless to slightly yellowish oil, having a faint amine-like odor. ... Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … A-Bite Cream …

Cinnamon oil

Approved
Experimental
Matched Products: … Nwk A-FV …

Sodium aurothiomalate

Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Gold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold Sodium Thiomalate per mL. It is most effective in active progressive rheumatoid arthritis and of little or no value in...
Approved
Investigational
Matched Description: … It is most effective in active progressive rheumatoid arthritis and of little or no value in the presence ... Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects ... Gold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold …
Matched Products: … MYOCRISIN INJECTION 20 MG (4% W/V) …

Tigecycline

Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil. It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was granted fast-track approval by the U.S. Food and Drug Administration (FDA) on June 17, 2005.
Approved
Matched Description: … Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil ... It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus ... It was granted fast-track approval by the U.S. Food and Drug Administration (FDA) on June 17, 2005. …
Matched Products: … TIGECLIN ® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE. ... TIGECICLINA 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... TIGEVITAE® 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …

Mifamurtide

Mifamurtide is an immunomodulator with antitumor activity via activation of macrophages and monocytes. Also called L-MTP-PE, mifamurtide may be a liposomal form of of the active ingredient MTP-PE, which is a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP). MDP is a motif present in all gram-positive and...
Approved
Experimental
Matched Iupac: … sodium (2R)-1-({2-[(2S)-2-[(4R)-4-carbamoyl-4-[(2S)-2-[(2R)-2-{[(2R,3R,4R,5R)-2-acetamido-4,5,6-trihydroxy …
Matched Description: … MDP is a motif present in all gram-positive and gram-negative bacterial walls that is recognized by different ... In a large, randomized, open-label, multicenter, phase III trial, the treatment of mifamurtide in conjunction ... a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP). …
Matched Products: … MEPACT 4 MG INFÜZYONLUK DISPERSIYON KONSANTRESI IÇIN TOZ ,FLAKON, 1 ADET …

Guanfacine

Guanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension but is now indicated as an extended release tablet for the treatment of ADHD. Guanfacine was first described in the literature in 1974. Guanfacine was granted FDA approval on 27 October 1986.
Approved
Investigational
Matched Description: … [L11277] Guanfacine was first described in the literature in 1974. ... Guanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially …
Matched Products: … GUAGO 4 MG UZATILMIŞ SALIMLI TABLET, 28 ADET ... ARİSLOW ER 4 MG UZATILMIŞ SALIMLI TABLET, 28 TABLET …

Cocaine

An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of...
Approved
Illicit
Matched Description: … It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in ... Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism ... It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse …
Matched Salts cas: … 53-21-4 …
Matched Products: … PMS-cocaine Hydrochloride Topical Sol 4% …

Beractant

Beractant is a pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Considered a natural source of surfactant as it is made from bovine lung extract, beractant contains a mixture of phospholipids, neutral lipids, fatty acids, and surfactant-associated proteins such as SP-B and SP-C. The...
Approved
Matched Description: … Beractant is a pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in ... a reduced incidence of pneumothorax and reduced mortality. ... Considered a natural source of surfactant as it is made from bovine lung extract, beractant contains …
Matched Products: … SURVANTA ® 4 ML …

Octreotide

Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues and causing metabolic dysfunction. In most cases, it results from an anterior pituitary growth hormone-releasing tumor. Typically, the feet, hands, and face grow abnormally large; organomegaly and insulin resistance may also occur. Acromegaly is...
Approved
Investigational
Matched Description: … [L14513] In the past, octreotide has been administered solely by injection. ... Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues ... [L14501] In most cases, it results from an anterior pituitary growth hormone-releasing tumor. …
Matched Salts cas: … 79517-01-4 …
Matched Products: … Siroctid 0,1 mg/ml Injektionslösung in einer Fertigspritze ... Siroctid 0,5 mg/ml Injektionslösung in einer Fertigspritze ... Siroctid 0,05 mg/ml Injektionslösung in einer Fertigspritze …

Penicillium chrysogenum var. chrysogenum

Penicillium chrysogenum var. chrysogenum is a fungus which can provoke allergic reactions. Penicillium chrysogenum var. chrysogenum extract is used in allergenic testing.
Approved
Matched Description: … Penicillium chrysogenum var. chrysogenum extract is used in allergenic testing. ... Penicillium chrysogenum var. chrysogenum is a fungus which can provoke allergic reactions. …
Matched Mixtures name: … Molds - Mold Mix 4 ... Molds - Mold Mix 4 ... Molds - Mold Mix 4 …

Bendamustine

Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine...
Approved
Investigational
Matched Iupac: … 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-1,3-benzodiazol-2-yl}butanoic acid …
Matched Description: … Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia ... Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups ... alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases resulting in …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index …
Matched Products: … PURPULZ ® 180 MG/4 ML ... GENSTINA® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …

Hyaluronic acid

Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not...
Approved
Vet approved
Matched Iupac: … (2S,3S,4R,5R,6R)-3-{[(2S,3R,5S,6R)-4-{[(2R,3R,4S,5S,6S)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]oxy}-3-acetamido ... hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-{[(2R,3R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4- …
Matched Description: … [A230133] Several preparations of hyaluronic acid have been approved by the FDA and are available in ... A popular use of hyaluronic acid in recent years is cosmetic injection due to its ability to minimize ... neural tissues; it was first isolated in 1934. …
Matched Salts cas: … 31799-91-4 …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 0.5% / Niacinamide 4% / Tretinoin 0.1% ... Hyaluronic Acid Sodium Salt 1% / Niacinamide 4% / Tacrolimus 0.1% ... Hyaluronic Acid Sodium Salt 0.5% / Niacinamide 4% / Tretinoin 0.05% …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … SYNOLIS V-A ... HIALSEC 4 MG/ML SOLUCIÓN OFTÁLMICA X 10 ML …

Aspergillus fumigatus

Aspergillus fumigatus is a fungus which can provoke allergic reactions. Aspergillus fumigatus extract is used in allergenic testing.
Approved
Matched Description: … Aspergillus fumigatus extract is used in allergenic testing. ... Aspergillus fumigatus is a fungus which can provoke allergic reactions. …
Matched Mixtures name: … Molds - Mold Mix 4 ... Molds - Mold Mix 4 ... Molds - Mold Mix 4 …

Beremagene geperpavec

Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector therapy. Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolysis bullosa (DEB). DEB is caused by mutations in the COL7A1 gene that...
Approved
Matched Description: … [L46916] DEB is caused by mutations in the _COL7A1_ gene that encodes collagen VII (COL7), a major component ... Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of ... Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector …
Matched Categories: … Cellular and Gene Therapy …

Nitroprusside

Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.
Approved
Investigational
Matched Description: … Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles ... Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Sodium Nitroprusside In 0.9% Sodium Chloride …
Displaying drugs 351 - 375 of 15219 in total