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Displaying drugs 351 - 375 of 8764 in total

Loxapine

An antipsychotic agent used in schizophrenia. [PubChem]
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Metolazone

A quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
Approved
Matched Categories: … combinations of sulfonamides …

Minaprine

Minaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive states. Like most antidepressants minaprine antagonizes behavioral despair. Minaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and weight gain.
Approved
Matched Description: … Minaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive ... Minaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Opium

Opium is the first substance of the diverse group of the opiates. It has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years by the Sumerians. During the years, opium was used as a sedative and hypnotic, but it was...
Approved
Illicit
Matched Description: … Opium is the first substance of the diverse group of the opiates. ... harmful effects of opium. ... in the category of isoquinolines. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Vespula vulgaris venom protein

Vespula vulgaris venom protein is an extract of Vespula vulgaris venom. Vespula vulgaris venom protein is used in allergenic testing.
Approved
Matched Description: … Vespula vulgaris venom protein is an extract of Vespula vulgaris venom. …
Matched Products: … ALUTARD SQ Wespengift Injektionssuspension (Anfangsbehandlung) (100 SQ E/ml, 1.000 SQ E/ml, 10.000 SQ …

Plantago lanceolata pollen

Plantago lanceolata pollen is the pollen of the Plantago lanceolata plant. Plantago lanceolata pollen is mainly used in allergenic testing.
Approved
Matched Description: … Plantago lanceolata pollen is the pollen of the Plantago lanceolata plant. …

Methylcellulose

Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3,...
Approved
Matched Description: … The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number ... of substituted hydroxyl groups per glucose with a theoretical maximum of 3, however more typical values ... It is available under a variety of trade names as a treatment for constipation. …
Matched Salts name: … Methylcellulose (100 MPa.s) …

Sitaxentan

Sitaxentan was marketed under the trade name Thelin for the treatment of pulmonary arterial hypertension (PAH) by Encysive Pharmaceuticals until Pfizer purchased Encysive in February 2008. In 2010, Pfizer voluntarily removed sitaxentan from the market over concerns of hepatotoxicity.
Approved
Investigational
Withdrawn
Matched Description: … In 2010, Pfizer voluntarily removed sitaxentan from the market over concerns of hepatotoxicity. ... Sitaxentan was marketed under the trade name Thelin for the treatment of pulmonary arterial hypertension …

Ciclopirox

Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. In particular, the agent is especially effective in treating Tinea versicolor.
Approved
Investigational
Matched Description: … , Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of …
Matched Products: … SEBİROX %1,5 ŞAMPUAN , 100 ML …

Cholecalciferol

Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Description: … vitamin d and are found in various types of food for daily intake [L5689]. ... Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin ... Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus …
Matched Mixtures name: … SANASOL 100 ML SURUP ... POLIVIT SURUP, 100 ML ... Chela Calmag-100 Plus Zinc D3 …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … ÇÖZELTİ İÇEREN AMPUL, 100 AMPUL ... ./10 ML ORAL DAMLA, ÇÖZELTİ, 100 ML …

Pregabalin

Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively characterized, there is evidence that pregabalin exerts its effects...
Approved
Investigational
Matched Description: … [A187190] Although as per the FDA Label the mechanism of action has not been definitively characterized ... , there is evidence that pregabalin exerts its effects by binding to the α2δ subunit of voltage-dependent …
Matched Products: … LYRICA 100 MG ... PREGATAB 100 MG ... Lyribastad 100 mg Hartkapseln …

Salmeterol

Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.[L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 adrenergic receptor agonist, salbutamol. Salmeterol was first described in the literature in 1988. Salmeterol's structure...
Approved
Matched Description: … long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of ... [L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 …
Matched Mixtures name: … SERETIDE 50/100 ACCUHALER 50 mcg/100 mcg ... Advair 100 Diskus ... SERETIDE DISKUS 100 …

Moxonidine

Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown...
Approved
Investigational
Matched Description: … Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild …

Methylergometrine

A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)
Approved
Matched Description: … A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed) …
Matched Products: … UTERJİN 0,2 MG IM AMPUL, 100 ADET …

Melphalan

Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. …

Levocarnitine

Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Approved
Investigational
Matched Description: … Constituent of striated muscle and liver. ... It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias …
Matched Products: … METACARTİN 100 MG/ML ŞURUP, 100 ML …

Minoxidil

A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Approved
Investigational
Matched Products: … TRIATOP®ESPUMA TÓPICA EN AEROSOL ... TYLCORE® ESPUMA TÓPICA EN AEROSOL ... MİNOX F2 % 2 ÇÖZELTİ KÖPÜK, 100 ML …

Maralixibat

Maralixibat (also known as SHP625, LUM001, and lopixibat) is an ileal bile acid transporter inhibitor, like odevixibat.[A236823,A239249,L38834] Maralixibat is indicated for the treatment of cholestatic pruritus in patients with Alagille syndrome. Previously, patients with cholestatic pruritus associated with Alagille syndrome were treated with antihistamines, rifampin, ursodeoxycholic acid, cholestyramine, naltrexone, and...
Approved
Investigational
Matched Description: … [L44396] On July 21, 2023, maralixibat was also approved by Health Canada.[L47541] ... [A236823,A239249,L38834] Maralixibat is indicated for the treatment of cholestatic pruritus in patients ... [A239249] No clinical trials have been performed to assess the efficacy of these treatments for cholestatic …

Ginkgo biloba

Ginkgo biloba extract contains a group of terpene lactones (notably, ginkgolides and diterpenes) and ginkgo flavone glycosides (notably, ginkgetin, bilobetin, and sciadopitysin) that have antioxidant and vasoactive properties. Most of the studies that investigate the effect of ginkgo biloba use the standardized extract of Ginkgo biloba (EGb) 761 (EGb761), which...
Approved
Investigational
Nutraceutical
Matched Description: … [A232389] Most of the studies that investigate the effect of _ginkgo biloba_ use the standardized extract ... _Ginkgo biloba_ extract contains a group of terpene lactones (notably, ginkgolides and diterpenes) and ... of _Ginkgo biloba_ (EGb) 761 (EGb761), which was developed by a German pharmaceutical company in 1964 …
Matched Mixtures name: … MEGINGO 10/50 MG EFERVESAN TABLET, 100 ADET ... MEGINGO 10/80 MG EFERVESAN TABLET, 100 ADET ... MEGINGO 20/50 MG EFERVESAN TABLET, 100 ADET …

Zafirlukast

Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once...
Approved
Investigational
Matched Description: … of the airways, build-up of mucus in the lungs and inflammation of the breathing passages. ... Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma ... Zafirlukast blocks the action of the cysteinyl leukotrienes on the CysLT1 receptors, thus reducing constriction …

Levomenol

Bisabolol, or more formally α-(−)-bisabolol or also known as levomenol, (-)-alpha-Bisabolol is found in fats and oils. (-)-alpha-Bisabolol is isolated from essential oil of Matricaria chamomilla (German chamomile) (-)-alpha-Bisabolol belongs to the family of Sesquiterpenes. These are terpenes with three consecutive isoprene units.
Approved
Experimental
Matched Iupac: … (2S)-6-methyl-2-[(1S)-4-methylcyclohex-3-en-1-yl]hept-5-en-2-ol …
Matched Description: … alpha-Bisabolol belongs to the family of Sesquiterpenes. ... . (-)-alpha-Bisabolol is isolated from essential oil of Matricaria chamomilla (German chamomile) (-)- …

Tick-borne encephalitis vaccine (whole virus, inactivated)

Tick-borne encephalitis (TBE) is a disease caused by the TBE virus (TBEV), transmitted by ticks from the genus Ixodes. The disease course is variable. Some patients will be asymptomatic or experience a mild febrile illness, while others will experience the full course including neurological symptoms. TBE often manifests in a...
Approved
Matched Description: … then a second phase characterized by various neurological symptoms falling under the categorizations of ... [A237520] Due to a paucity of effective safe and effective acute therapeutic agents, vaccination remains ... recover fully following neurological TBE, neurological sequelae can last for years and rare chronic forms of …

Iptacopan

Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor B. Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and subsequently C5 convertase. This is...
Approved
Investigational
Matched Description: … of the PIGA gene. ... [A262581] This is of particular importance to PNH, where one of the disease hallmarks is the mutation ... [A262566] Factor B is a positive regulator of the alternative complement pathway, where it activates …

Ceftobiprole

Ceftobiprole is a fifth-generation semisynthetic cephalosporin antibacterial which is available commercially as the prodrug ceftobiprole medocaril. Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative bacteria, including antibiotic-resistant strains of Staphylcoccus aureus (methicillin-resistant Staphylococcus aureus; MRSA). The EMA's Committee for Medicinal Products for Human Use (CHMP)...
Approved
Investigational
Matched Description: … medocaril in February 2010, recommending the refusal of its marketing authorization in the European ... activity against both Gram-positive and Gram-negative bacteria, including antibiotic-resistant strains of ... The EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a negative opinion of ceftobiprole …

Fondaparinux

Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they are cleaved into monomeric units. The monomeric sequence in heparin and HS...
Approved
Investigational
Matched Description: … a O-methyl group at the reducing end of the molecule. ... ); and in the management of ST segment elevation myocardial infarction (STEMI). ... Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and …
Displaying drugs 351 - 375 of 8764 in total