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Displaying drugs 3951 - 3975 of 9853 in total
Prinaberel is an estrogen receptor beta agonist.
Investigational
Matched Iupac: … 7-ethenyl-2-(3-fluoro-4-hydroxyphenyl)-1,3-benzoxazol-5-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Icaritin has been used in trials studying the treatment of Solid Tumors, Metastatic Breast Cancer, and Hepatocellular Carcinoma (HCC).
Investigational
Matched Iupac: … 3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … 3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)quinolin-2(1H)-one …
Matched Iupac: … 3-[4-hydroxy-1-(3-methylbutyl)-2-oxo-1,2-dihydroquinolin-3-yl]-4H-1lambda6,2,4-benzothiadiazine-1,1-dione …
Experimental
Matched Name: … (3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXYLATE …
Matched Iupac: … (1R,3R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-pyrrolo[2,3-b]pyridine-3-carboxylate …
Experimental
Matched Name: … [(3S)-9-hydroxy-1-methyl-10-oxo-4,10-dihydro-3H-benzo[g]isochromen-3-yl]acetic acid …
Matched Iupac: … 2-[(3S)-9-hydroxy-1-methyl-10-oxo-3H,4H,10H-naphtho[2,3-c]pyran-3-yl]acetic acid …
Experimental
Matched Name: … 3-(4-Amino-1-Tert-Butyl-1h-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenol …
Matched Iupac: … 3-{4-amino-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl}phenol …
Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … 5-[1-(4-methoxyphenyl)-1H-benzimidazol-6-yl]-1,3,4-oxadiazole-2(3H)-thione …
Matched Iupac: … 5-[1-(4-methoxyphenyl)-1H-1,3-benzodiazol-6-yl]-2,3-dihydro-1,3,4-oxadiazole-2-thione …
Nitroparacetamol (NCX-701) is a newly synthesized nitric oxide-releasing derivative of paracetamol.
Investigational
NOX-700, an new orally active dithiocarbamate-based nitric oxide (NO) blocking agent that is in development for the treatment of diabetes mellitus (type 2 diabetes). In animal studies, NOX-700 lowered serum glucose, improved glucose tolerance, and reduced the percentage of total glycated hemoglobin. Immunohistochemical studies on pancreatic tissue also showed that...
Investigational
KW-7158 is a tricyclic compound with a non-cholingergic mechanism of action for the treatment of "urinary urgency," "frequent urination" and "urinary incontinence" associated with bladder overactivity (involuntary abnormal contraction of the bladder). The therapeutic effects of KW-7158 in overactive bladder may be due to the activation of A-type K(+) channels...
Investigational
Matched Iupac: … ),3(7),5,11,13-pentaen-14-yl}propanamide ... (2S)-3,3,3-trifluoro-2-hydroxy-2-methyl-N-{2,9,9-trioxo-4,9λ⁶-dithiatricyclo[8.4.0.0³,⁷]tetradeca-1(10 …
MIV-701 is a selective, potent inhibitor of the protease Cathepsin K. It is developed for the treatment of osteoporosis.
Investigational
ABT-751 has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.
Investigational
Matched Synonyms: … N-[2-(4-hydroxyanilino)-3-pyridinyl]-4-methoxybenzenesulfonamide ... N-[2-(4-hydroxyanilino)pyridin-3-yl]-4-methoxybenzenesulfonamide ... N-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide …
Matched Iupac: … N-{2-[(4-hydroxyphenyl)amino]pyridin-3-yl}-4-methoxybenzene-1-sulfonamide …
GTX-758 is under investigation in clinical trial NCT01420861 (GTx-758 on Serum Prostate-specific Antigen (PSA) in Men With Castrate Resistant Prostate Cancer).
Investigational
Matched Iupac: … 3-fluoro-N-(4-fluorophenyl)-4-hydroxy-N-(4-hydroxyphenyl)benzamide …
PRI-724 is under investigation in clinical trial NCT03620474 (Safety and Effectiveness of PRI-724 for Hepatitis C or B Virus Derived Liver Cirrhosis).
Investigational
Matched Iupac: … (4-{[(6S,9S,9aS)-1-(benzylcarbamoyl)-2,9-dimethyl-4,7-dioxo-8-[(quinolin-8-yl)methyl]-octahydro-1H-pyrazino …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pardoprunox has been used in trials studying the treatment of Early Stage Parkinson's Disease and Advanced Stage Parkinson's Disease. Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties.
Investigational
Matched Iupac: … 7-(4-methylpiperazin-1-yl)-2,3-dihydro-1,3-benzoxazol-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … 7-(2-hydroxypropyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Experimental
Matched Name: … 3-phenyl-5-(1H-pyrazol-3-yl)isoxazole …
Matched Iupac: … 3-phenyl-5-(1H-pyrazol-3-yl)-1,2-oxazole …
Flubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.
Experimental
Withdrawn
Matched Iupac: … methyl N-[5-(4-fluorobenzoyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Products: … FLUBENDAZOL 20 MG/ML …
Efonidipine is a calcium channel blocker of the dihydropyridine class, commercialized by Shionogi & Co. (Japan). Initially, it was marketed in 1995 under the trade name, Landel. The drug has been shown to block T-type in addition to L-type calcium channels [A7844, A32001]. It has also been studied in atherosclerosis...
Experimental
Matched Iupac: … )-1,4-dihydropyridine-3-carboxylate ... 2-[benzyl(phenyl)amino]ethyl 5-(5,5-dimethyl-2-oxo-1,3,2λ⁵-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl …
Matched Salts cas: … 111011-53-1
Matched Categories: … Heterocyclic Compounds, 1-Ring …
RTA 744 is a novel anthracycline derivative that crosses the blood-brain barrier and shows significant potential for the treatment of primary and metastatic brain cancers. Anthracyclines are one of the most broadly used and effective classes of cancer therapies; however, they are not used to treat brain cancers because current...
Investigational
AT7519 is a selective inhibitor of certain Cyclin Dependent Kinases (CDKs) leading to tumour regression. It is developed by Astex for the treatment of solid tumours and haematological malignancies.
Investigational
Matched Synonyms: … 4-{[(2,6-dichlorophenyl)carbonyl]amino}-N-piperidin-4-yl-1H-pyrazole-3-carboxamide …
Matched Iupac: … 4-(2,6-dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
MK-7145 has been used in trials studying the treatment of Hypertension and Renal Insufficiency.
Investigational
Matched Iupac: … -1-yl}ethyl]-4-methyl-1,3-dihydro-2-benzofuran-1-one ... 5-[(1R)-1-hydroxy-2-{4-[(2R)-2-hydroxy-2-(4-methyl-1-oxo-1,3-dihydro-2-benzofuran-5-yl)ethyl]piperazin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
AEE788 has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.
Investigational
Matched Iupac: … 6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine …
ABP-700 is under investigation in clinical trial NCT02800590 (Study to Investigate the Safety and Efficacy of 3 Dosing Regimens of ABP-700 for Procedural Sedation in Adult Participants Undergoing Colonoscopy).
Investigational
Matched Iupac: … 1-(methoxycarbonyl)cyclopropyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate …
Matched Description: … under investigation in clinical trial NCT02800590 (Study to Investigate the Safety and Efficacy of 3
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 3951 - 3975 of 9853 in total