Advanced Filter

Filter by Group

Filter by Market Availability

Displaying drugs 376 - 400 of 841 in total
Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain and cerebrospinal fluid, into interstitial fluid and plasma. As a...
Approved
Investigational
Matched Synonyms: … (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexaol ... (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol
Matched Iupac: … (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol
Matched Description: … or sugar alcohol, in fruits and vegetables. ... As a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure ... cerebrospinal fluid, into interstitial fluid and plasma. …
Matched Mixtures name: … INFUSOL M20S (Mannitol 17.5%w/v and Sorbitol 2.5%w/v Intravenous Infusion) ... TERUFLEX Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND ... (Saving Platelets) with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) and
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Cough and Cold Preparations ... Diet, Food, and Nutrition ... Blood Substitutes and Perfusion Solutions …
An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
Approved
Matched Products: … Tridione
Investigational
Matched Synonyms: … -5-ylmethyl)hexahydro-2H-pyrazino[2,1-c][1,2,4]triazine-1(6H)-carboxamide ... (6S,9aS)-N-benzyl-6-(4-hydroxybenzyl)-4,7-dioxo-2-((3-(pyridin-2-yl)isoxazol-5-yl)methyl)-8-(quinolin …
Despite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes were sought after immediately . Finally, in 1903 the world's first synthetic and non-addictive local anesthetic, amylocaine, was synthesized and patented under the name Forneaucaine by Ernest Fourneau at the Pasteur Institute . Elsewhere in English...
Approved
Withdrawn
Matched Synonyms: … 1-(Dimethylamino)-2-methyl-2-butanol benzoate
Matched Iupac: … 1-(dimethylamino)-2-methylbutan-2-yl benzoate
Matched Description: … and prilocaine in the 1940s and 1950s superseded and made the use of amylocaine obsolete. ... and patented under the name Forneaucaine by Ernest Fourneau at the Pasteur Institute [L1882]. ... Finally, in 1903 the world's first synthetic and non-addictive local anesthetic, amylocaine, was synthesized …
Propylparaben is used in allergenic testing.
Approved
Experimental
Matched Synonyms: … 4-Hydroxybenzoic acid propyl ester ... p-Hydroxybenzoic propyl ester ... 4-Hydroxybenzoic acid, propyl ester …
Matched Categories: … Benzoates
Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … .)-(118-145)-PEPTIDE (1-28) WITH HUMAN SOMATOTROPIN (GROWTH HORMONE, GH) (29-219) AND TWO TANDEM COPIES …
Matched Description: … adolescence and regulating metabolic function in adulthood. ... of somatrogon and allows its once-weekly dosing. ... by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Anterior Pituitary Lobe Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists …
Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder and irritable bowel syndrome.[A6556,A182555,A234659,L7967] Though it is commonly prescribed, its recommendation may have been based on a small...
Approved
Matched Synonyms: … 2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarboxylate ... Bicyclohexyl-1-carboxylic acid 2-diethylamino-ethyl ester …
Matched Iupac: … 2-(diethylamino)ethyl [1,1'-bi(cyclohexane)]-1-carboxylate …
Matched Description: … and irritable bowel syndrome. ... Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor ... of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder …
Matched Categories: … Alimentary Tract and Metabolism …
Benzimate is the lead compound selected from a series of compounds known as benzimidazoles. The anti-cancer and anti-viral activity of the benzimidazoles was originally investigated by the Proctor & Gamble Company beginning in the 1990's. It is currently under investigation by AmpliMed and is in phase I of clinical trial.
Investigational
Matched Name: … Benzimate
Matched Description: … It is currently under investigation by AmpliMed and is in phase I of clinical trial. ... The anti-cancer and anti-viral activity of the benzimidazoles was originally investigated by the Proctor ... Benzimate is the lead compound selected from a series of compounds known as benzimidazoles. …
Hydrocortamate is a synthetic glucocorticoid used for its anti-inflammatory or immunosuppressive properties to treat inflammation due to corticosteroid-responsive dermatoses. Glucocorticoids are a class of steroid hormones characterised by an ability to bind with the cortisol receptor and trigger a variety of important cardiovascular, metabolic, immunologic and homeostatic effects.
Approved
Matched Synonyms: … 17-Hydroxycorticosterone, 21-(diethylamino)acetate …
Matched Iupac: … oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl 2-(diethylamino
Matched Description: … trigger a variety of important cardiovascular, metabolic, immunologic and homeostatic effects. ... Glucocorticoids are a class of steroid hormones characterised by an ability to bind with the cortisol receptor and
Becatecarin is a derivative of rebeccamycin.
Investigational
Matched Synonyms: … 6-(2-(DIETHYLAMINO)ETHYL)-REBECCAMYCIN …
Matched Iupac: … 5,21-dichloro-13-[2-(diethylamino)ethyl]-3-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan …
Experimental
Matched Name: … 2-[(Dioxidophosphoranyl)oxy]benzoate
Matched Iupac: … 2-[(oxidophosphonoyl)oxy]benzoate
Profenamine (also known as ethopropazine) is a medication derived from phenothiazine. It is primarily used as an antidyskinetic to treat Parkinsonism. It is sold under the trade name Parsitan in Canada. In the US, the marketing of profenamine has been discontinued.
Approved
Matched Synonyms: … 10-[2-(diethylamino)propyl]phenothiazine ... 10-[2-(diethylamino)-1-propyl]phenothiazine ... 2-diethylamino-1-propyl-N-dibenzoparathiazine …
Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride. Similar to other local anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. The pharmacological profile of...
Approved
Investigational
Matched Synonyms: … 2-(Diethylamino)ethyl 4-amino-2-chlorobenzoate ... 4-amino-2-chlorobenzoic acid 2-(diethylamino)ethyl ester …
Matched Iupac: … 2-(diethylamino)ethyl 4-amino-2-chlorobenzoate …
Matched Description: … [A252952] Chloroprocaine can be given as an injection, and is available in formulations with and without ... formulation can be used for lumbar and caudal epidural blocks. ... increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and
Matched Categories: … Benzoates
Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Iupac: … trihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^{3,10}.0^{4,7}]heptadec-13-en-2-yl benzoate
Matched Description: … Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel]. ... chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and ... microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Oncotaxel Concentrate and solvent for solution for infusion 40 mg/ ml …
Experimental
Matched Synonyms: … Ethyl p-(piperidinoacetylamino)benzoate
Matched Iupac: … ethyl 4-[2-(piperidin-1-yl)acetamido]benzoate
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Description: … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration …
Matched Mixtures name: … Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Fluocinolone Acetonide …
Matched Categories: … ciprofloxacin and tinidazole ... ciprofloxacin and ornidazole ... ciprofloxacin and metronidazole ... Drug-Related Side Effects and Adverse Reactions ... Ophthalmological and Otological Preparations …
Matched Products: … Ciprofloxacin and Dextrose ... CILOXAN STERILE OPHTHALMIC AND OTIC SOLUTION 0.3% ... Ciprofloxacin Hexal 250 mg - Filmtabletten …
Acacia allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Plants and plant parts, gum, acacia or arabic acacia senegal …
Triapine has been used in trials studying the treatment of Leukemia, Lung Cancer, Kidney Cancer, Prostate Cancer, and Pancreatic Cancer, among others.
Investigational
Matched Name: … Triapine
Matched Description: … Cancer, and Pancreatic Cancer, among others. ... Triapine has been used in trials studying the treatment of Leukemia, Lung Cancer, Kidney Cancer, Prostate …
Approved
Experimental
Matched Synonyms: … Butyl p-hydroxy benzoate
Matched Categories: … Benzoates
Toxic alkylating agent used in industry; also as antineoplastic and research tool to produce chromosome aberrations and cancers.
Experimental
Matched Synonyms: … 2,4,6-tri(1-aziridinyl)-1,3,5-triazine ... 2,4,6-tris(1-aziridinyl)-s-triazine ... 2,4,6-tris(1-aziridinyl)-1,3,5-triazine
Matched Iupac: … tris(aziridin-1-yl)-1,3,5-triazine
Matched Description: … aberrations and cancers. ... Toxic alkylating agent used in industry; also as antineoplastic and research tool to produce chromosome …
Matched Categories: … Triazines
Experimental
Matched Name: … 1,2,4-Triazole
Matched Iupac: … 1H-1,2,4-triazole
Benzoin is a white crystalline compound prepared by condensation of benzaldehyde in potassium cyanide, and is used in organic syntheses. This should not be confused with benzoin gum from STYRAX (see DB11222). Benzoin is an FDA-approved colour additive used for marking fruits and vegetables.
Approved
Experimental
Matched Synonyms: … phenyl-α-hydroxybenzyl ketone ... alpha-Hydroxybenzyl phenyl ketone ... Phenyl-alpha-hydroxybenzyl ketone …
Matched Description: … Benzoin is a white crystalline compound prepared by condensation of benzaldehyde in potassium cyanide, and ... Benzoin is an FDA-approved colour additive used for marking fruits and vegetables. …
Approved
Experimental
Matched Synonyms: … 4-hydroxybenzoic acid ethyl ester ... p-hydroxybenzoic acid ethyl ester …
Matched Categories: … Benzoates
Experimental
Matched Synonyms: … p-Hydroxybenzoic acid …
Matched Name: … 4-hydroxybenzoic acid …
Matched Iupac: … 4-hydroxybenzoic acid …
Matched Categories: … Benzoates
Cycloguanil is the active metabolite of proguanil.
Approved
Matched Synonyms: … Chlorguanide triazine
Matched Iupac: … 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Displaying drugs 376 - 400 of 841 in total