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Displaying drugs 376 - 400 of 2456 in total
Verpasep caltespen is a recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a...
Investigational
Matched Synonyms: … Recombinant fusion protein of Mycobacterium bovis BCG Hsp65 and HPV16 E7 …
Matched Description: … E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen ... recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from _Mycobacterium bovis_, and ... Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be …
Asfotase alfa is a first-in-class bone-targeted enzyme replacement therapy designed to address the underlying cause of hypophosphatasia (HPP)—deficient alkaline phosphatase (ALP). Hypophosphatasia is almost always fatal when severe skeletal disease is obvious at birth. By replacing deficient ALP, treatment with Asfotase Alfa aims to improve the elevated enzyme substrate levels...
Approved
Investigational
Matched Synonyms: … Asfotase alfa
Matched Name: … Asfotase alfa
Matched Description: … Asfotase alfa was first approved by Pharmaceuticals and Medicals Devices Agency of Japan (PMDA) on July ... levels and improve the body's ability to mineralize bone, thereby preventing serious skeletal and systemic ... patient morbidity and premature death. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... asfotase alfa ... Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Olipudase alfa is recombinant human acid sphingomyelinase. It is the first and only enzyme replacement therapy in the world for the treatment of Acid Sphingomyelinase Deficiency (ASMD), also known as Niemann–Pick disease. ASMD is a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a deficiency...
Approved
Investigational
Matched Synonyms: … Olipudase alfa
Matched Name: … Olipudase alfa
Matched Description: … Olipudase alfa is recombinant human acid sphingomyelinase. ... [A251590] It is the first and only enzyme replacement therapy in the world for the treatment of Acid ... , liver, spleen, kidneys, and bone marrow. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... olipudase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Valanafusp alfa is under investigation in clinical trial NCT03071341 (Extension Study Evaluating Long Term Safety and Activity of AGT-181 in Children With MPS I).
Investigational
Matched Synonyms: … Valanafusp alfa
Matched Name: … Valanafusp alfa
Matched Description: … Term Safety and Activity of AGT-181 in Children With MPS I). ... Valanafusp alfa is under investigation in clinical trial NCT03071341 (Extension Study Evaluating Long …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Experimental
Matched Synonyms: … Vensobafusp alfa
Matched Name: … Vensobafusp alfa
Lepunafusp alfa is under investigation in clinical trial NCT04453085 (An Extension Study of JR-171-101 Study in Patients With MPS I).
Investigational
Matched Synonyms: … Lepunafusp alfa
Matched Name: … Lepunafusp alfa
Matched Description: … Lepunafusp alfa is under investigation in clinical trial NCT04453085 (An Extension Study of JR-171-101 …
Approved
Investigational
Matched Synonyms: … Medronic acid ... Acido medronico ... Acide medronique …
Matched Name: … Medronic acid
Matched Iupac: … (phosphonomethyl)phosphonic acid
Royal jelly is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Honey Bee Secretion Used in the Nutrition of Larvae and Adult Queens Secreted From Worker Bee Hypopharyngeal …
Matched Mixtures name: … Shine Oramin Natural Korean Ginseng + Royal Jelly with Multivitamins and Minerals. …
Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. Bacitracin was granted FDA approval on 29 July 1948.[A181997,L7748]
Approved
Vet approved
Matched Iupac: … heptaoxo-1,4,7,10,13,16,19-heptaazacyclopentacosan-21-yl]carbamoyl}-2-methylbutyl]carbamoyl}butanoic acid
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Bacitracin Zinc ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids
Matched Products: … Up and Up First Aid Antibiotic ... Up and Up Bacitracin first aid …
Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly...
Approved
Matched Synonyms: … phenylbenzimidazole sulfonic acid
Matched Iupac: … 2-phenyl-1H-1,3-benzodiazole-6-sulfonic acid
Matched Description: … Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that ... It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter ... Due to its water solubility, ensulizole is commonly used in products formulated to feel light and less …
Matched Mixtures name: … Polyglutamic Acid Dewy Sunscreen SPF 30 ... Advanced Firming and Anti Wrinkle ... g and h Protect Body …
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Matched Products: … Dolce and Gabbana The Foundation Perfect Matte Broadspectrum SPF 20 All shades ... Lancome Paris Teint Idole Ultra Care and Glow Skincare Foundation Broad Spectrum SPF 27 Sunscreen …
Fluticasone propionate is a synthetic glucocorticoid[F4355,F4358][FDA Label]. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications[F4355,F4358][FDA Label]. Fluticasone propionate was first approved in 1990 .
Approved
Matched Description: … These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory …
Matched Mixtures name: … Fluticasone Propionate and Salmeterol ... Fluticasone Propionate and Salmeterol ... Fluticasone Propionate and Salmeterol …
Matched Products: … Up and Up Allergy Relief Nasal ... Up and Up allergy relief nasal ... Berkley and Jensen Allergy Relief …
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop...
Approved
Investigational
Matched Synonyms: … Etacrinic acid ... Etacrynic acid ... Acide étacrynique …
Matched Name: … Etacrynic acid
Matched Iupac: … 2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid
Matched Description: … Henle, but also in the proximal and distal tubules. ... A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of ... This pharmacological action results in excretion of these ions, increased urinary output, and reduction …
Matched Categories: … Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids ... etacrynic acid ... Aryloxyacetic Acid Derivatives …
Matched Products: … Ethacrynic Acid ... Ethacrynic acid
Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78...
Approved
Matched Synonyms: … Folitropina alfa ... Follitrophin alfa ... Follitropin alfa
Matched Description: … The alpha- and beta- subunits have 92 and 111 amino acids. ... 7 and Asn 24. ... Numerous physio-chemical tests and bioassays indicate that follitropin beta and follitropin alpha are …
Matched Mixtures name: … Pergoveris 150IU/75IU powder and solvent for solution for injection ... Pergoveris Powder and Solvent for Solution for Injection 150iu/75iu ... MENOGON 75 IU Powder and Solvent for solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... follitropin alfa ... Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Sex Hormones and Modulators of the Genital System …
Matched Products: … GONAL-F® 450 IU/0.75 ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... GONAL-F® 75 IU (5.5MCG) POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation . Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass . Docusate can be orally or rectally administered. Docusate is on the World...
Approved
Matched Iupac: … 1,4-bis[(2-ethylhexyl)oxy]-1,4-dioxobutane-2-sulfonic acid
Matched Description: … Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and
Matched Mixtures name: … PNV Ferrous Fumarate Docusate Folic Acid ... Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA ... Senna and Docusate Sodium …
Matched Categories: … Alimentary Tract and Metabolism ... Softener and Emollient Laxatives …
Matched Products: … Up and up stool softener ... Stool Softener easy and gentle …
Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO...
Approved
Matched Synonyms: … Epoetin alfa ... Epoetin alfa rDNA ... Epoetina alfa
Matched Description: … The product contains the identical amino acid sequence of isolated natural erythropoietin and has the ... States, followed by other alfa and beta formulations. ... Epoetin alfa is a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins …
Matched Products: … EPOETIN ALFA ... Epoetin Alfa Hexal ... EPOETIN ALFA HEXAL 1000IE …
Tefidsogene civaparvovec, formerly known as SB-913, is an investigational therapy for genome editing. It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes. Developed by Sangamo...
Experimental
Matched Synonyms: … IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS EXONS 2-9 FROM HIDS AND
Matched Description: … It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system …
A liquid that functions as a strong oxidizing agent. It has an acrid odor and is used as a disinfectant.
Experimental
Matched Synonyms: … Acide peracetique ... Ethaneperoxic acid ... Acido peroxiacetico …
Matched Name: … Peracetic acid
Matched Iupac: … ethaneperoxoic acid
Matched Description: … It has an acrid odor and is used as a disinfectant. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids
Matched Products: … Dr.Vir Germ Peroyxacetic acid Multi-disinfectant ... Dr.Vir Germ Peroxyacetic acid Multi-disinfectant …
Simoctocog alfa is a recombinant B-domain deleted (BDD) rFVIII produced in genetically modified human embryonic kidney (HEK) 293F cells. The harvested product is concentrated and purified by a series of chromatography steps. It is an antihemorrhagic agent used as a replacement therapy in individuals with Haemophilia A who lack the...
Approved
Matched Synonyms: … Simoctocog alfa
Matched Name: … Simoctocog alfa
Matched Description: … Simoctocog alfa is a glycoprotein consisting of 1440 amino acids with an approximate molecular mass of ... The harvested product is concentrated and purified by a series of chromatography steps. ... replaced by a 16 amino acid linker. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Rasdegafusp alfa is under investigation in clinical trial NCT03206047 (Atezolizumab, Guadecitabine, and CDX-1401 Vaccine in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer).
Investigational
Matched Synonyms: … Rasdegafusp alfa
Matched Name: … Rasdegafusp alfa
Matched Description: … Rasdegafusp alfa is under investigation in clinical trial NCT03206047 (Atezolizumab, Guadecitabine, and
Myasthenia gravis (MG) is an autoimmune disorder characterized by significant muscle weakness - particularly in the eye, throat, and extremities - caused by autoantibodies attacking the neuromuscular junction. The production of IgG autoantibodies against acetylcholine receptors (AChRs) is one of the more common pathophysiological mechanisms behind MG, and results in...
Approved
Investigational
Matched Synonyms: … Efgartigimod alfa
Matched Name: … Efgartigimod alfa
Matched Description: … Efgartigimod alfa for intravenous use was granted FDA approval on December 17, 2021[L39501] and European ... [L43190] A formulation for subcutaneous use that combines efgartigimod alfa and hyaluronidase was approved ... [L39509] By antagonizing this interaction, efgartigimod alfa prevents this recycling phase and thus decreases …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... efgartigimod alfa
Bintrafusp alfa is under investigation in clinical trial NCT03833661 (M7824 Monotherapy in Locally Advanced or Metastatic Second Line (2L) Biliary Tract Cancer (Cholangiocarcinoma and Gallbladder Cancer)).
Investigational
Matched Synonyms: … Bintrafusp alfa
Matched Name: … Bintrafusp alfa
Matched Description: … or Metastatic Second Line (2L) Biliary Tract Cancer (Cholangiocarcinoma and Gallbladder Cancer)). ... Bintrafusp alfa is under investigation in clinical trial NCT03833661 (M7824 Monotherapy in Locally Advanced …
Efizonerimod alfa is under investigation in clinical trial NCT02221960 (A Phase 1 Study to Evaluate MEDI6383 Alone and in Combination With MEDI4736 in Adult Subjects With Select Advanced Solid Tumors).
Investigational
Matched Synonyms: … Efizonerimod alfa
Matched Name: … Efizonerimod alfa
Matched Description: … Alone and in Combination With MEDI4736 in Adult Subjects With Select Advanced Solid Tumors). ... Efizonerimod alfa is under investigation in clinical trial NCT02221960 (A Phase 1 Study to Evaluate MEDI6383 …
Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … .)-(118-145)-PEPTIDE (1-28) WITH HUMAN SOMATOTROPIN (GROWTH HORMONE, GH) (29-219) AND TWO TANDEM COPIES ... OF HUMAN CHORIOGONADOTROPIN SUBUNIT .BETA. ... FUSION PROTEIN OF HUMAN CHORIOGONADOTROPIN SUBUNIT .BETA. …
Matched Description: … of somatrogon and allows its once-weekly dosing. ... adolescence and regulating metabolic function in adulthood. ... by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Anterior Pituitary Lobe Hormones and Analogues ... Somatropin and Somatropin Agonists …
Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as...
Approved
Investigational
Matched Synonyms: … Vestronidase alfa ... Vestronidase alfa-vjbk …
Matched Name: … Vestronidase alfa
Matched Description: … The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid ... In clinical trials, vestronidase alfa treatment demonstrated improvement and stabilization in motor symptoms ... Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that …
Matched Categories: … vestronidase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Approved
Investigational
Matched Synonyms: … 6-Aminocaproic acid ... Aminocaproic acid ... 6-aminohexanoic acid
Matched Name: … Aminocaproic acid
Matched Iupac: … 6-aminohexanoic acid
Matched Mixtures name: … NAVI Black and C-Clinic ... Relief and Nature Toothpast E Jasmine Mint …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids
Matched Products: … Aminocaproic Acid ... Aminocaproic acid
Displaying drugs 376 - 400 of 2456 in total