Displaying drugs 401 - 425 of 3252 in total
Starch, corn
Corn starch refers to the starch extracted from the corn grain that is commonly used as a food ingredient and chemical additive. Starch is any of a group of polysaccharides of the general formula (C6-H10-O5)n, composed of a long-chain polymer of glucose in the form of amylose and amylopectin. Starch...
Approved
Nutraceutical
Resmetirom
Resmetirom is a thyroid hormone receptor-beta (THR-beta) agonist. On March 14, 2024, it was approved by the FDA as the first treatment of liver fibrosis due to noncirrhotic non-alcoholic steatohepatitis (NASH), which is a form of non-alcoholic fatty liver disease (NAFLD). Thyroid hormones directly regulate lipid metabolism in the liver;...
Approved
Investigational
Histrelin
Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher potency. Histrelin implants are non-biodegradable, diffusion-controlled, hydrogel polymer reservoirs containing histrelin acetate that...
Approved
Withdrawn
Denosumab
Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption via inhibiting RANK-mediated activation of osteoclasts. It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss. Chemically, it consists of 2 heavy...
Approved
Methadone
Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. As a full MOR agonist, methadone mimics the natural effects of the body's opioids, endorphins, and enkephalins through the release of neurotransmitters involved in pain transmission. It also has a...
Approved
Matched Description: … substitution of illicit opioids with the long-acting opioids used in OAT is to prevent withdrawal symptoms for 24 …
Matched Products: … Methasan 10 mg-Tabletten ... METHADOSE® 10 MG TABLETAS ... ABL METAPAD COMPRIMIDOS 10 MG …
Matched Products: … Methasan 10 mg-Tabletten ... METHADOSE® 10 MG TABLETAS ... ABL METAPAD COMPRIMIDOS 10 MG …
Verapamil
Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Formoterol
Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers....
Approved
Investigational
Matched Mixtures name: … FLUTIFORM® 250 MCG / 10 MCG ... FLUTIFORM® 250 MCG / 10 MCG ... ฟลูติฟอร์ม 250 ไมโครกรัม / 10 ไมโครกรัม …
Matched Products: … FORMOTEROL FUMARATO 10 MCG ... FORMAIR 9 MG İNHALASYON İÇİN TOZ İÇEREN KAPSÜL, 60 ADET ... FORMAIR 9 MG İNHALASYON İÇİN TOZ İÇEREN KAPSÜL, 120 ADET …
Matched Products: … FORMOTEROL FUMARATO 10 MCG ... FORMAIR 9 MG İNHALASYON İÇİN TOZ İÇEREN KAPSÜL, 60 ADET ... FORMAIR 9 MG İNHALASYON İÇİN TOZ İÇEREN KAPSÜL, 120 ADET …
Nabilone
Nabilone (marketed as Cesamet) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). Although structurally distinct from THC, nabilone mimics THC's structure and pharmacological activity through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, however it is considered to be twice as...
Approved
Investigational
Matched Iupac: … 6aR,10aR)-1-hydroxy-6,6-dimethyl-3-(2-methyloctan-2-yl)-6H,6aH,7H,8H,9H,10H,10aH-benzo[c]isochromen-9- …
Matched Description: … Nabilone (marketed as Cesamet) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary …
Matched Description: … Nabilone (marketed as Cesamet) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary …
Elbasvir
Elbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, an infectious liver disease caused by infection with hepatitis C virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in...
Approved
Matched Iupac: … phenyl-8-oxa-10-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-1(17),2(7),3,5,11(16),12,14-heptaen-5 ... -14-{2-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl}-9- …
Ipecac
Ipecac is obtained from the plant Cephaelis ipecacuanha and contains a number of emetic alkaloids including emetine and cephaeline. Ipecac was approved by Health Canada as an OTC but all those products are now discontinued. The FDA does not have currently any approved product containing ipecac, however, ipecac as an...
Approved
Withdrawn
Fexinidazole
Human African trypanosomiasis (HAT, also colloquially referred to as sleeping sickness), caused by T. brucei gambiense and T. brucei rhodesiense, remains a moderate risk (>1/10,000 inhabitants per year in endemic areas) despite focussed control efforts. Transmitted by the bite of an infected tsetse fly, HAT is biphasic with a first...
Approved
Investigational
Fidaxomicin
Fidaxomicin is a novel macrolide antibiotic used in the treatment of diarrhea caused by Clostridioides (formerly Clostridium) difficile in adult and pediatric patients over the age of 6 months. Fidaxomicin is a naturally-occurring 18-member macrocycle derived from fermentation. Because fidaxomicin contains an 18-membered lactone ring in its structure, it is...
Approved
Matched Iupac: … 18S)-12-{[(2R,3S,4R,5S)-3,4-dihydroxy-6,6-dimethyl-5-[(2-methylpropanoyl)oxy]oxan-2-yl]oxy}-11-ethyl-8- …
Bacitracin
Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. Bacitracin was granted FDA approval on 29 July 1948.[A181997,L7748]
Approved
Vet approved
Matched Iupac: … 15S,18R,21S)-18-(3-aminopropyl)-12-benzyl-15-[(2S)-butan-2-yl]-3-(carbamoylmethyl)-6-(carboxymethyl)-9- …
Matched Description: … Bacitracin is a combination of at least 9 bacitracins. …
Matched Mixtures name: … 10 Person ANSI ... GFA First Aid 24 Unit Metal Case …
Matched Products: … Albac Powder 10% ... Bacitracin Methylene Disalicylate Granule 10% W/W ... YH Bacitracin Methylene Disalicylate 10% W/W Granule …
Matched Description: … Bacitracin is a combination of at least 9 bacitracins. …
Matched Mixtures name: … 10 Person ANSI ... GFA First Aid 24 Unit Metal Case …
Matched Products: … Albac Powder 10% ... Bacitracin Methylene Disalicylate Granule 10% W/W ... YH Bacitracin Methylene Disalicylate 10% W/W Granule …
Fenofibric acid
Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia. It works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol.[A32038,L12855] Due to its high hydrophilicity and poor absorption profile, prodrug ,fenofibrate, and other conjugated compounds...
Approved
Matched Salts cas: … 856676-23-8 …
Matched Mixtures name: … FENOVAS®10 MG ... FENOVAS®10 MG …
Matched Mixtures name: … FENOVAS®10 MG ... FENOVAS®10 MG …
Zilucoplan
Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses. On October 17, 2023, zilucoplan gained its first FDA approval for the treatment of...
Approved
Matched Iupac: … 2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{1-[(2S,5S,8S,11S,14S,22S)-11-benzyl-8- …
Streptococcus pneumoniae type 8 capsular polysaccharide antigen
Streptococcus pneumoniae type 8 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 8 of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Synonyms: … PNEUMOCOCCAL POLYSACCHARIDE SEROTYPE 8 ... pneumococcal capsular polysaccharide type 8 vaccine …
Matched Name: … Streptococcus pneumoniae type 8 capsular polysaccharide antigen …
Matched Description: … capsular polysaccharides from the invasive pneumococcal type 8 of *Streptococcus pneumoniae*. ... Streptococcus pneumoniae type 8 capsular polysaccharide antigen is a vaccine that contains highly purified …
Matched Name: … Streptococcus pneumoniae type 8 capsular polysaccharide antigen …
Matched Description: … capsular polysaccharides from the invasive pneumococcal type 8 of *Streptococcus pneumoniae*. ... Streptococcus pneumoniae type 8 capsular polysaccharide antigen is a vaccine that contains highly purified …
Tetracosactide
Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone. ACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production of corticosteroids in the adrenal cortex. Tetracosactide exhibits the same...
Approved
Matched Synonyms: … ATCH (1-24) ... corticotropin-(1-24) ... α1-24-corticotrophin …
Matched Description: … Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid ... ACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production …
Matched Description: … Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid ... ACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production …
Dihydroergocristine
Dihydroergocristine is part of the ergoloid mixture products. It is a semisynthetic ergot alkaloid and thus, it is characterized by a structural skeleton formed by an alkaloid ergoline. To know more about ergoloid mixtures, please visit DB01049.
Approved
Experimental
Matched Synonyms: … 9,10-dihydroergocristine …
Matched Salts cas: … 24730-10-7 …
Matched Salts cas: … 24730-10-7 …
Dihydroergocornine
Dihydroergocornine is one of the dihydrogenated ergot compounds that present very large hypotensive effects. It is an artificial derivative of the crude extract of ergot and later purified, ergocornine. The formation of dihydroergocornine implies the hydrogenation of the double bonds in the lysergic acid. Dihydroergocornine presents a formula of 9,10...
Approved
Matched Synonyms: … 9,10-dihydroergocornine …
Matched Description: … [A32965] Dihydroergocornine presents a formula of 9,10 alpha-dihydro-12'-hydroxy-2',5'alpha-bis(1-methylethyl …
Matched Description: … [A32965] Dihydroergocornine presents a formula of 9,10 alpha-dihydro-12'-hydroxy-2',5'alpha-bis(1-methylethyl …
Tetrabenazine
A drug formerly used as an antipsychotic but now used primarily in the symptomatic treatment of various hyperkinetic disorders. It is a monoamine depletor and used as symptomatic treatment of chorea associated with Huntington's disease. FDA approved on August 15, 2008.
Approved
Investigational
Matched Synonyms: … 1,2,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one ... 2-oxo-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzoquinolizine ... 2-oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizine …
Matched Iupac: … 9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-one …
Matched Iupac: … 9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-one …
Calcifediol
The major circulating metabolite of vitamin D3 (cholecalciferol). It is produced in the liver and is the best indicator of the body's vitamin D stores. It is effective in the treatment of rickets and osteomalacia, both in azotemic and non-azotemic patients. Calcifediol also has mineralizing properties.
Approved
Nutraceutical
Matched Synonyms: … (3S,5Z,7E)-9,10-secocholesta-5,7,10-triene-3,25-diol ... (3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-3,25-diol ... (5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-triene-3,25-diol …
Matched Mixtures name: … HEPATAMINE %8 500 ML(SETLI) ... HEPATAMINE %8 500 ML(SETSIZ) …
Matched Mixtures name: … HEPATAMINE %8 500 ML(SETLI) ... HEPATAMINE %8 500 ML(SETSIZ) …
Streptococcus pneumoniae type 8 capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 8 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 8 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Name: … Streptococcus pneumoniae type 8 capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 8 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is ... sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae* serotype 8 …
Matched Description: … Streptococcus pneumoniae type 8 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is ... sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae* serotype 8 …
Methoxsalen
A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation.
Approved
Matched Synonyms: … 9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one ... 8-MP ... 8-MOP …
Matched Iupac: … 9-methoxy-7H-furo[3,2-g]chromen-7-one …
Matched Products: … 8-mop ... Oxsoralen 10 mg - Kapseln …
Matched Iupac: … 9-methoxy-7H-furo[3,2-g]chromen-7-one …
Matched Products: … 8-mop ... Oxsoralen 10 mg - Kapseln …
Dimenhydrinate
Dimehydrinate was first described in the literature in 1949, and patented in 1950. Early research into dimenhydrinate focused on its role as an antihistamine for urticaria; the treatment of motion sickness was an accidental discovery. Dimenhydrinate, also known as B-dimethylaminoethyl benzohydrol ether 8-chlorotheophyllinate, is indicated to prevent nausea, vomiting, and...
Approved
Matched Synonyms: … diphenhydramine 8-chlorotheophylline ... diphenhydramine 8-chlorotheophyllinate ... (O-benzhydryl(dimethylamino)ethanol) 8-chlorotheophyllinate …
Matched Iupac: … 8-chloro-1,3-dimethyl-2,3,6,9-tetrahydro-1H-purine-2,6-dione; [2-(diphenylmethoxy)ethyl]dimethylamine …
Matched Description: … ] in a salt form, with 53%-55.5% dried diphenhydramine, and 44%-47% died 8-chlorotheophylline. ... [L32980,L32985,L32995] Dimenhydrinate is a combination of [Diphenhydramine] and [8-chlorotheophylline ... [A233130] Dimenhydrinate, also known as B-dimethylaminoethyl benzohydrol ether 8-chlorotheophyllinate …
Matched Products: … VOTMINE INJECTION 10 ML VIAL (50MG/ML) …
Matched Iupac: … 8-chloro-1,3-dimethyl-2,3,6,9-tetrahydro-1H-purine-2,6-dione; [2-(diphenylmethoxy)ethyl]dimethylamine …
Matched Description: … ] in a salt form, with 53%-55.5% dried diphenhydramine, and 44%-47% died 8-chlorotheophylline. ... [L32980,L32985,L32995] Dimenhydrinate is a combination of [Diphenhydramine] and [8-chlorotheophylline ... [A233130] Dimenhydrinate, also known as B-dimethylaminoethyl benzohydrol ether 8-chlorotheophyllinate …
Matched Products: … VOTMINE INJECTION 10 ML VIAL (50MG/ML) …
Clioquinol
Clioquinol was withdrawn in 1983 due to neurotoxicity.
Approved
Vet approved
Withdrawn
Matched Synonyms: … 5-Chloro-7-iodo-8-quinolinol ... 5-Chlor-7-jod-8-hydroxy-chinolin ... 5-chloro-7-iodoquinolin-8-ol …
Matched Iupac: … 5-chloro-7-iodoquinolin-8-ol …
Matched Iupac: … 5-chloro-7-iodoquinolin-8-ol …
Displaying drugs 401 - 425 of 3252 in total