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Displaying drugs 401 - 425 of 15307 in total

Alogliptin

Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.
Approved
Matched Description: … It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. ... Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (> …
Matched Mixtures name: … Alogliptin and Pioglitazone ... Alogliptin and Pioglitazone ... Alogliptin and Pioglitazone …
Matched Categories: … Drugs Used in Diabetes ... Alimentary Tract and Metabolism ... metformin and alogliptin ... pioglitazone and alogliptin ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Human thrombin

Human thrombin is a sterile solution, pH 6.8-7.2, containing highly purified human thrombin for the activation of clotting. Thrombin is a highly specific serine protease encoded by the F2 gene that transforms soluble fibrinogen into insoluble fibrin. This transformation mimics the final coagulation cascade step which involves the clotting mass...
Approved
Matched Description: … achieves hemostasis and sealing of open tissues. ... In particular, while human thrombin products are made from pooled human source plasma, recombinant thrombin ... chromatographic purification of prothrombin from cryo-poor plasma followed by activation with calcium chloride …

Flunitrazepam

Flunitrazepam is a benzodiazepine with pharmacologic actions similar to those of diazepam that can cause anterograde amnesia. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
Approved
Illicit
Matched Description: … Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives …

Povidone

Povidone, also known as polyvinylpyrrolidone (PVP) or polyvidone, is a synthetic water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant in eye drops. It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier. When in...
Approved
Withdrawn
Matched Description: … many pharmaceutical tablets and lubricant in eye drops. ... It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier ... [DB06812] can be found in over-the-counter topical solutions, ointment, pessaries, liquid soaps and surgical …
Matched Mixtures name: … Rohto Sun and Sport ... Redness reliever and Lubricant ... Meijer Advanced Redness and Irritation Relief …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Metocurine

Dimethyltubocurarinium (INN) or metocurine (USAN), also known as dimethyltubocurarine, is a non-depolarizing muscle relaxant. Patients on chronic anticonvulsant drugs are relatively resistant to metocurine.
Approved
Matched Salts name: … Metocurine chloride …

Mechlorethamine

A vesicant and necrotizing irritant destructive to mucous membranes, mechlorethamine is an alkylating drug. It was formerly used as a war gas. The hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. It causes severe gastrointestinal and bone marrow damage. The FDA granted marketing approval for the orphan...
Approved
Investigational
Matched Description: … The hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. ... IB mycosis fungoides-type cutaneous T-cell lymphoma (CTCL) in patients who have received prior skin-directed ... It causes severe gastrointestinal and bone marrow damage. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Compounds used in a research, industrial, or household setting …

Zafirlukast

Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once...
Approved
Investigational
Matched Description: … an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in ... the lungs and inflammation of the breathing passages. ... It is available as a tablet and is usually dosed twice daily. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Dermatophagoides farinae

Dermatophagoides farinae extracts are sterile solutions used for intradermal testing or subcutaneous immunotherapy. This combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.
Approved
Matched Mixtures name: … Standardized Mite Mix Dermatophagoides farinae and Dermatophagoides pteronyssinus ... Standardized Mite Mix Dermatophagoides farinae and Dermatophagoides pteronyssinus ... Standardized Mite Mix, Dermatophagoides pteronyssinus and Dermatophagoides farinae, 10000 AU per mL …

Niclosamide

Niclosamide is an antihelminthic used for the treatment of tapeworm infections. Helminths (worms) are multicellular organisms that infect very large numbers of humans and cause a broad range of diseases. Over 1 billion people are infected with intestinal nematodes, and many millions are infected with filarial nematodes, flukes, and tapeworms....
Approved
Investigational
Vet approved
Matched Description: … by Bayer in 1996. ... nematodes, flukes, and tapeworms. ... They are an even greater problem in domestic animals. …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Salicylanilide and Derivatives ... Antiparasitic Products, Insecticides and Repellents …

Influenza A virus A/South Australia/55/2014 IVR-175 (H3N2) hemagglutinin antigen (propiolactone inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …

Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) hemagglutinin antigen (UV, formaldehyde inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …

Influenza A virus A/Christchurch/16/2010 NIB-74XP (H1N1) hemagglutinin antigen (formaldehyde inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …

Influenza A virus A/Singapore/gp1908/2015 IVR-180 (H1N1) hemagglutinin antigen (UV, formaldehyde inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …

Influenza A virus A/Guangdong-Maonan/SWL1536/2019 CNIC-1909 (H1N1) antigen (UV, formaldehyde inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …

Trypan blue free acid

Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence of a mature cataract. This is done to aid in visualization before creating the continuous curvilinear capsulorhexis.
Approved
Matched Description: … Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence ... This is done to aid in visualization before creating the continuous curvilinear capsulorhexis. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Ambenonium

Ambenonium is a cholinesterase inhibitor. It is used in the management of myasthenia gravis.
Approved
Matched Description: … It is used in the management of myasthenia gravis. …
Matched Salts name: … Ambenonium chloride …

Plecanatide

Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation (CIC). It should not be used in children less than six years of age, and should be avoided in patients six years to 18 years of age
Approved
Investigational
Matched Description: … It should not be used in children less than six years of age, and should be avoided in patients six years ... Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Japanese Encephalitis Vaccine, Inactivated, Adsorbed

Approved
Investigational

Nonoxynol-9

Nonoxynol-9 (N-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives. When present in the vagina during intercourse, they immobilize/inactivate/damage and/or kill sperms without eliciting systemic effects. N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams,...
Approved
Withdrawn
Matched Description: … N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and ... It is the most commonly used spermicidal contraceptive in the UK and the USA. ... When present in the vagina during intercourse, they immobilize/inactivate/damage and/or kill sperms without …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Bictegravir

Bictegravir is a recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 infection. It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet.
Approved
Investigational
Matched Description: … of HIV-1 and HIV-2 infection. ... Bictegravir is a recently approved investigational drug that has been used in trials studying the treatment ... It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet. …
Matched Categories: … emtricitabine, tenofovir alafenamide and bictegravir ... Antivirals used in combination for the treatment of HIV infections …

Quinidine barbiturate

The administration of quinidine derivatives helps to observe various skin and mucosal reactions. A papulopurpuric eruption in a patient (without thrombopenia) can be developed who is taking quinidine phenylethyl barbiturate intermittently and at reintroduction.(PMID: 9739909)
Approved
Matched Description: … A papulopurpuric eruption in a patient (without thrombopenia) can be developed who is taking quinidine ... phenylethyl barbiturate intermittently and at reintroduction. ... The administration of quinidine derivatives helps to observe various skin and mucosal reactions. …

Beractant

Beractant is a pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Considered a natural source of surfactant as it is made from bovine lung extract, beractant contains a mixture of phospholipids, neutral lipids, fatty acids, and surfactant-associated proteins such as SP-B and SP-C. The...
Approved
Matched Description: … It is suspended in 0.9% sodium chloride solution, and heat-sterilized. ... the leading cause of death in preterm infants. ... surfactant-associated proteins such as SP-B and SP-C. …

Saxagliptin

Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.
Approved
Matched Mixtures name: … Saxagliptin and Metformin ... Saxagliptin and Metformin ... Saxagliptin and Metformin …
Matched Categories: … Drugs Used in Diabetes ... Alimentary Tract and Metabolism ... metformin and saxagliptin ... Amino Acids, Peptides, and Proteins ... saxagliptin and dapagliflozin …

Tragacanth

Tragacanth allergenic extract is used in allergenic testing.
Approved
Matched Description: … Tragacanth allergenic extract is used in allergenic testing. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Thiosulfuric acid

Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate. Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching agent. Sodium thiosulfate is rapidly degraded...
Approved
Investigational
Matched Description: … Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate ... it is frequently used in conjunction with sodium nitrite (a salt form of [nitrous acid]). ... [A252827] Sodium thiosulfate is rapidly degraded in the stomach; therefore, it is normally administered …
Matched Mixtures name: … Sodium polysulthionate and folic acid ... Sodium Polysulthionate and Folic Acid …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 401 - 425 of 15307 in total