Displaying drugs 4301 - 4325 of 11495 in total
Cerulenin
Cerulenin is an antifungal agent whose activity interferes with or otherwise acts to prevent the formation of fatty acids and sterols. In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity. It is also shown to inhibit feeding and induce...
Experimental
Matched Description: … In sterol synthesis, inhibits HMG-CoA synthetase activity. …
Savolitinib
Savolitinib has been used in trials studying the treatment and health services research of Tumor, Food Effect, Gastric Cancer, Health Subjects, and Colorectal Cancer, among others.
Investigational
Matched Iupac: … 4-{1-[(1S)-1-{imidazo[1,2-a]pyridin-6-yl}ethyl]-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl}-1-methyl-1H-pyrazole …
Lintuzumab satetraxetan AC-225
Lintuzumab actinium Ac-225 is under investigation in clinical trial NCT00672165 (Targeted Atomic Nano-Generators (Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody HuM195) in Patients With Advanced Myeloid Malignancies).
Investigational
Matched International brands: … Actimab-A …
Leucine
An essential branched-chain amino acid important for hemoglobin formation.
Investigational
Nutraceutical
Pexacerfont
Pexacerfont has been investigated for the treatment of Alcoholism, Anxiety Disorder, Alcohol Dependence, and Alcohol-Related Disorders.
Investigational
Matched Iupac: … N-[(2R)-butan-2-yl]-8-(6-methoxy-2-methylpyridin-3-yl)-2,7-dimethylpyrazolo[1,5-a][1,3,5]triazin-4-amine …
Dipraglurant
Dipraglurant has been used in trials studying the treatment of Parkinson's Disease. It is a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator (NAM).
Investigational
Matched Iupac: … 2-(4-{6-fluoroimidazo[1,2-a]pyridin-2-yl}but-1-yn-1-yl)pyridine …
Matched Description: … It is a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator (NAM). …
Matched Description: … It is a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator (NAM). …
Elesclomol
Elesclomol is a novel, injectable, drug candidate that kills cancer cells by elevating oxidative stress levels beyond a breaking point, triggering programmed cell death. In preclinical models elesclomol showed potent killing of a broad range of cancer cell types at high doses, and an ability to strongly enhance the efficacy...
Investigational
Matched Description: … levels beyond a breaking point, triggering programmed cell death. ... Elesclomol is a novel, injectable, drug candidate that kills cancer cells by elevating oxidative stress ... In preclinical models elesclomol showed potent killing of a broad range of cancer cell types at high …
Decoglurant
Decoglurant has been used in trials studying the treatment of Major Depressive Disorder.
Investigational
Matched Iupac: … 5-{2-[7-(trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]ethynyl}pyridin- …
Tenofovir
Tenofovir is an acyclic nucleotide diester analog of adenosine monophosphate. In the most strict sense and due to the fact that it presents a phosphate group bound to the nitrogenous base, it is determined as an actual nucleotide analog. The antiviral activities of tenofovir were first reported in 1993 and...
Experimental
Investigational
Matched Description: … [A37693] In the most strict sense and due to the fact that it presents a phosphate group bound to the …
Calcium hypochlorite
Experimental
Matched Mixtures name: … POLYLAB T-EUSOL (SOLUTION A & B) ... SC Pharma Eusol Solution Max A & B ... POLYLAB T-EUSOL( SOLUTION A & B) …
Hypericin
Hypericin is under investigation for the treatment of Cutaneous T-cell Lymphoma.
Investigational
Matched Categories: … Benz(a)Anthracenes …
Fazadinium bromide
Experimental
Matched Iupac: … -1H-4lambda5-imidazo[1,2-a]pyridin-4-ylium dibromide ... 3-methyl-1-[(E)-2-{3-methyl-2-phenyl-1H-4lambda5-imidazo[1,2-a]pyridin-4-ylium-1-yl}diazen-1-yl]-2-phenyl …
Isoleucine
An essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of leucine. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.
Investigational
Nutraceutical
Minodronic acid
Investigational
Matched Iupac: … (1-hydroxy-2-{imidazo[1,2-a]pyridin-3-yl}-1-phosphonoethyl)phosphonic acid …
Garadacimab
Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and Safety of CSL312 on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy Through a PICC Line).
Investigational
Matched Description: … Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy ... on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy Through a …
Verucerfont
Verucerfont has been used in trials studying the treatment of Congenital Adrenal Hyperplasia.
Investigational
Matched Iupac: … 4-methoxy-2-methylphenyl)-2,5-dimethyl-N-[(1S)-1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl]pyrazolo[1,5-a] …
Xylitol
Xylitol is a naturally occurring five-carbon sugar alcohol found in most plant material, including many fruits and vegetables. Xylitol-rich plant materials include birch and beechwood . It is widely used as a sugar substitute and in "sugar-free" food products. The effects of xylitol on dental caries have been widely studied,...
Experimental
Investigational
Matched Description: … It is widely used as a sugar substitute and in "sugar-free" food products. ... Xylitol is a naturally occurring five-carbon sugar alcohol found in most plant material, including many ... Xylitol is a non-fermentable sugar alcohol by most plaque bacteria, indicating that it cannot be fermented …
Matched Mixtures name: … Fluor-a-day ... Fluor-a-day ... Fluor-a-day …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Mixtures name: … Fluor-a-day ... Fluor-a-day ... Fluor-a-day …
Matched Categories: … Compounds used in a research, industrial, or household setting …
2-(Pyrido[1,2-E]Purin-4-Yl)Amino-Ethanol
Experimental
Denecimig
Delpacibart is a humanized, bispecific, bivalent monoclonal antibody against coagulation factor 9.
Investigational
Matched Description: … Delpacibart is a humanized, bispecific, bivalent monoclonal antibody against coagulation factor 9. …
Alvespimycin
Alvespimycin is a derivative of geldanamycin and heat shock protein (HSP) 90 inhibitor. It has been used in trials studying the treatment of solid tumor in various cancer as an antitumor agent. In comparison to the first HSP90 inhibitor tanespimycin, it exhibits some pharmacologically desirable properties such as reduced metabolic...
Investigational
Matched Description: … Alvespimycin is a derivative of geldanamycin and heat shock protein (HSP) 90 inhibitor. …
Matched Categories: … HSP90 Heat-Shock Proteins …
Matched Categories: … HSP90 Heat-Shock Proteins …
Edotecarin
Edotecarin is a novel, non-camptothecin, DNA topoisomerase I inhibitor. It is member of the class of compounds called indolocarbazoles.
Investigational
Matched Description: … Edotecarin is a novel, non-camptothecin, DNA topoisomerase I inhibitor. …
Anagliptin
Anagliptin is under investigation for the treatment of LDL Cholesterol, Coronary Disease, Diabetes Mellitus, Glycosylated Hemoglobin, and Dipeptidyl-Peptidase 4 Inhibitors.
Investigational
Matched Iupac: … N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine …
Displaying drugs 4301 - 4325 of 11495 in total