Displaying drugs 4376 - 4400 of 11755 in total
Verucerfont
Verucerfont has been used in trials studying the treatment of Congenital Adrenal Hyperplasia.
Investigational
Matched Iupac: … 4-methoxy-2-methylphenyl)-2,5-dimethyl-N-[(1S)-1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl]pyrazolo[1,5-a] …
Methylmalonic Acid
A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA. [PubChem]
Experimental
Matched Description: … This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl ... CoA. ... A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. …
2-(Pyrido[1,2-E]Purin-4-Yl)Amino-Ethanol
Experimental
IPI-493
IPI-493 has been used in trials studying the treatment of Advanced Malignancies.
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Prezatide copper
Prezatide is a tripeptide consisting of glycine, histidine, and lysine which readily forms a complex with copper ions . Prezatide is used in cosmetic products for the skin and hair. It is known to aid wound healing and its potential applications in chronic obstructive pulmonary disease and metastatic colon cancer...
Experimental
Matched Description: … Prezatide is a tripeptide consisting of glycine, histidine, and lysine which readily forms a complex …
Tanespimycin
Tanespimycin, manufactured by Conforma Therapeutics is under development as a small molecule inhibitor of heat shock protein 90 (HSP90). It is developed for the treatment of several types of cancer, solid tumors or chronic myelogenous leukemia.
Investigational
Matched Description: … of heat shock protein 90 (HSP90). ... Tanespimycin, manufactured by Conforma Therapeutics is under development as a small molecule inhibitor …
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Retaspimycin
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Becatecarin
Becatecarin is a derivative of rebeccamycin.
Investigational
Matched Description: … Becatecarin is a derivative of [rebeccamycin]. …
XL-888
XL888 has been used in trials studying the treatment of Cancer and Melanoma.
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
AUY922
AUY922 has been used in trials studying the treatment of Lymphoma, Breast Cancer, Metastatic Disease, Advanced Solid Tumors, and Hematologic Neoplasms, among others.
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
LY-2090314
Ly2090314 has been used in trials studying the treatment of Leukemia, Advanced Cancer, and Pancreatic Cancer.
Investigational
Matched Iupac: … piperidine-1-carbonyl)-1,10-diazatricyclo[6.4.1.0^{4,13}]trideca-2,4,6,8(13)-tetraen-3-yl]-4-{imidazo[1,2-a] …
Anagliptin
Anagliptin is under investigation for the treatment of LDL Cholesterol, Coronary Disease, Diabetes Mellitus, Glycosylated Hemoglobin, and Dipeptidyl-Peptidase 4 Inhibitors.
Investigational
Matched Iupac: … N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine …
Indiplon
Indiplon has been used in trials studying the treatment of Insomnia and Depression.
Investigational
Matched Iupac: … N-methyl-N-{3-[3-(thiophene-2-carbonyl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl}acetamide …
DiaPep 277
DiaPep 277 is a 24-mer laboratory-made peptide derived from Hsp60(437-460).
Investigational
Matched Description: … DiaPep 277 is a 24-mer laboratory-made peptide derived from Hsp60(437-460). …
Matched Categories: … Heat-Shock Proteins …
Matched Categories: … Heat-Shock Proteins …
Edotecarin
Edotecarin is a novel, non-camptothecin, DNA topoisomerase I inhibitor. It is member of the class of compounds called indolocarbazoles.
Investigational
Matched Description: … Edotecarin is a novel, non-camptothecin, DNA topoisomerase I inhibitor. …
Coumermycin A1
Experimental
TAK-475
TAK-475 is a "squalene synthase inhibitor", a type of cholesterol-lowering drug that has not yet been brought to market.
Investigational
Matched Description: … TAK-475 is a "squalene synthase inhibitor", a type of cholesterol-lowering drug that has not yet been …
Lestaurtinib
Investigational
AV-COVID-19
AV-COVID-19 is a vaccine composed of autologous dendritic cells loaded with SARS-CoV-2 antigens and with or without Granulocyte-macrophage colony-stimulating factor (GM-CSF).
The vaccine is created from the receiving patients’ isolated peripheral blood monocytes. The monocytes are then differentiated in vitro into dendritic cells with IL-4 and GM-CSF, incubated with SARS-CoV-2...
Investigational
Matched Description: … AV-COVID-19 is a vaccine composed of autologous dendritic cells loaded with SARS-CoV-2 antigens and with …
7-Hydroxystaurosporine
Experimental
Investigational
Staurosporine
An indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
Experimental
Matched Description: … An indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses …
Omburtamab
CD276 (B7-H3) is a B7/CD28 immunoglobulin superfamily member frequently expressed among solid human tumours.[A242487, A242492] Omburtamab, formerly the murine anti-B7-H3 antibody 8H9, and its humanized forms are currently under clinical development for use in various cancers. Omburtamab is under investigation in clinical trial NCT03275402 (131i-omburtamab Radioimmunotherapy for Neuroblastoma Central Nervous...
Investigational
Matched Description: … CD276 (B7-H3) is a B7/CD28 immunoglobulin superfamily member frequently expressed among solid human tumours …
MK-8245
MK-8245 has been used in trials studying the treatment of Type 2 Diabetes Mellitus.
Investigational
Matched Categories: … Stearoyl-CoA Desaturase, antagonists & inhibitors …
Displaying drugs 4376 - 4400 of 11755 in total