Displaying drugs 4451 - 4475 of 11512 in total
Zanidatamab
According to Zymeworks, "ZW25 is a bispecific antibody that can simultaneously bind two non-overlapping epitopes, known as biparatopic binding, of HER2 resulting in dual HER2 signal blockade, increased binding and removal of HER2 protein from the cell surface, and potent effector function. These combined mechanisms of action have led to...
Investigational
Matched Description: … According to Zymeworks, "ZW25 is a bispecific antibody that can simultaneously bind two non-overlapping …
Clomethiazole
Clomethiazole is a well-established γ-aminobutyric acid (GABAA)-mimetic drug. It is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol withdrawal. It is a drug which is structurally related to thiamine (vitamin B1) but acts like a sedative, hypnotic, muscle relaxant and anticonvulsant. It...
Investigational
Matched Description: … It is a drug which is structurally related to thiamine (vitamin B1) but acts like a sedative, hypnotic ... Clomethiazole is a well-established γ-aminobutyric acid (GABAA)-mimetic drug. ... It is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
AUY922
AUY922 has been used in trials studying the treatment of Lymphoma, Breast Cancer, Metastatic Disease, Advanced Solid Tumors, and Hematologic Neoplasms, among others.
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Batroxobin
Batroxobin is a defibrinogenating hemostatic agent derived from the venom of a pit viper, Bothrops atrox moojeni. In addition to batroxobin, the venom of Bothrops atrox has a composition of 10.2% neutral carbohydrate. Batroxobin is a serine protease, which cleaves the 16 Arginine - 17 Glycine bond in fibrinogen. The...
Experimental
Matched Description: … Batroxobin is a defibrinogenating hemostatic agent derived from the venom of a pit viper, Bothrops atrox ... Batroxobin will also bind fibrinogen in a manner different than thrombin and with a higher affinity. ... Batroxobin is a serine protease, which cleaves the 16 Arginine - 17 Glycine bond in fibrinogen. …
Matched Categories: … Venombin A …
Matched Categories: … Venombin A …
Tea tree oil
Tea tree oil is an essential oil derived mainly from the Australian native plant Melaleuca alternifolia via steam distillation of the of the leaves and terminal branches . It may be referred to as Melaleuca alternifolia oil. It has been a popular ingredient in a variety of household and cosmetic...
Experimental
Nutraceutical
Matched Description: … It has been a popular ingredient in a variety of household and cosmetic products due to its antiseptic …
Matched Mixtures name: … Muscle and Joint Heat Cream …
Matched Mixtures name: … Muscle and Joint Heat Cream …
Priliximab
Investigational
Pentetrazol
Pentetrazol, also known as pentylenetetrazole, is a gamma-aminobutyric acid type A (GABAA) receptor antagonist that was approved by the FDA until 1982.
Experimental
Withdrawn
Matched Iupac: … 5H,6H,7H,8H,9H-[1,2,3,4]tetrazolo[1,5-a]azepine …
Matched Description: … Pentetrazol, also known as pentylenetetrazole, is a gamma-aminobutyric acid type A (GABAA) …
Matched Description: … Pentetrazol, also known as pentylenetetrazole, is a gamma-aminobutyric acid type A (GABAA) …
Orvacabtagene autoleucel
Investigational
Lecithin
A complex mixture of phospholipids, glycolipids, triglycerides, phosphatidylcholines, phosphatidylethanolamines, and phosphatidylinositols.
Experimental
Matched Description: … A complex mixture of phospholipids, glycolipids, triglycerides, phosphatidylcholines, phosphatidylethanolamines …
Matched Mixtures name: … ONE A DAY TABLET …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Mixtures name: … ONE A DAY TABLET …
Matched Categories: … Compounds used in a research, industrial, or household setting …
CD8+ enriched young tumor infiltrating lymphocytes
Investigational
Dibromothymoquinone
At low concentrations, this compound inhibits reduction of conventional hydrophilic electron acceptors, probably acting as a plastoquinone antagonist. At higher concentrations, it acts as an electron acceptor, intercepting electrons either before or at the site of its inhibitory activity. [PubChem]
Experimental
Matched Description: … this compound inhibits reduction of conventional hydrophilic electron acceptors, probably acting as a …
NeuroCell-PD
Investigational
Mevastatin
Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. It was the first discovered agent belonging to the class of cholesterol-lowering medications known as statins. During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) discovered a class of compounds that...
Experimental
Matched Description: … Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 ... times greater than the HMG-CoA substrate itself. ... Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. …
Matched Categories: … Hydroxymethylglutaryl-CoA Reductase Inhibitors …
Matched Categories: … Hydroxymethylglutaryl-CoA Reductase Inhibitors …
Frexalimab
Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis).
Investigational
Japanese encephalitis vaccine (live, attenuated)
Experimental
PHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINE
Experimental
Matched Iupac: … 4-{[6-(2,6-dichlorobenzoyl)imidazo[1,2-a]pyridin-2-yl]amino}benzene-1-sulfonamide …
Xylose-Derived Imidazole
Experimental
Matched Iupac: … (6R,7S,8S)-5H,6H,7H,8H-imidazo[1,2-a]pyridine-6,7,8-triol …
DiaPep 277
DiaPep 277 is a 24-mer laboratory-made peptide derived from Hsp60(437-460).
Investigational
Matched Description: … DiaPep 277 is a 24-mer laboratory-made peptide derived from Hsp60(437-460). …
Matched Categories: … Heat-Shock Proteins …
Matched Categories: … Heat-Shock Proteins …
mRNA-3927
mRNA-3927 is an investigational mRNA therapy that consists of two mRNAs that encode for the alpha and beta subunits of the mitochondrial enzyme propionyl-CoA carboxylase (PCC) encapsulated within a lipid nanoparticle (LNP). Developed by Moderna Inc., it is being investigated for the treatment of propionic acidemia.
Investigational
Matched Description: … carboxylase (PCC) encapsulated within a lipid nanoparticle (LNP). ... consists of two mRNAs that encode for the alpha and beta subunits of the mitochondrial enzyme propionyl-CoA …
Zeluvalimab
Zeluvalimab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Investigational
Ubamatamab
Ubamatamab is under investigation in clinical trial NCT03564340 (Study of REGN4018 Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers).
Investigational
Recombinant human CD4 immunoglobulin G
Investigational
Displaying drugs 4451 - 4475 of 11512 in total