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Displaying drugs 426 - 450 of 12317 in total

Drotaverine

Drotaverine is an antispasmodic drug that works by inhibiting phosphodiesterase-4 (PDE4). It is a benzylisoquinoline derivative that is structurally related to papaverine, although it displays more potent antispasmodic activities than papaverine. Drotaverine has been used in the symptomatic treatment of various spastic conditions, such as gastrointestinal diseases, biliary dyskinesia, and...
Approved
Investigational
Matched Iupac: … (1Z)-1-[(3,4-diethoxyphenyl)methylidene]-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline …
Matched Description: … Drotaverine is an antispasmodic drug that works by inhibiting phosphodiesterase-4 (PDE4). …
Matched Categories: … Phosphodiesterase 4 Inhibitors …

Didanosine

A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral...
Approved
Matched Description: … A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced …

Nisoldipine

Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nisoldipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Nisoldipine may be used in alone...
Approved
Matched Synonyms: … isobutyl methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Iupac: … 3-methyl 5-(2-methylpropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Minaprine

Minaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive states. Like most antidepressants minaprine antagonizes behavioral despair. Minaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and weight gain.
Approved
Matched Synonyms: … 4-(2-((4-Methyl-6-phenyl-3-pyridazinyl)amino)ethyl)morpholine ... N-(4-Methyl-6-phenyl-3-pyridazinyl)-4-morpholineethanamine ... 4-Methyl-3-(2-morpholinoethylamino)-6-phenylpyridazin …
Matched Iupac: … 4-methyl-N-[2-(morpholin-4-yl)ethyl]-6-phenylpyridazin-3-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Butylscopolamine

Butylscopolamine is a peripherally acting antimuscarinic, anticholinergic agent. It is used to treat pain and discomfort caused by abdominal cramps, menstrual cramps, or other spasmodic activity in the digestive system. It is also effective at preventing bladder spasms. It is not a pain medication in the normal sense, since it...
Approved
Investigational
Vet approved
Matched Iupac: … (1R,2R,4S,5S,7R)-9-butyl-7-{[(2S)-3-hydroxy-2-phenylpropanoyl]oxy}-9-methyl-3-oxa-9-azatricyclo[3.3.1.0 …
Matched Salts cas: … 149-64-4 …
Matched Products: … MOLIT 20 MG/ ML ENJEKSİYONLUK ÇÖZELTİ, 3 ADET ... ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 3 AMPUL ... Buscapina 20 mg/1 ml - Ampullen …

Barium sulfate

Barium sulfate is an inorganic compound with the chemical formula BaSO4 . Barium sulfate occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield . This drug is used as a contrast agent in...
Approved
Matched Products: … R-X 1 G/ML SÜSPANSİYON ... E.Z.CAT BARYUM SULFAT SUSPANSIYON 1 X 225 ML ... Micropaque 1 g/ml Suspension zur oralen oder rektalen Anwendung …

Diaminopyrimidine oxide

Diaminopyrimidine oxide is a compound similar to minoxidil which is used to aid in hair growth.
Approved
Matched Synonyms: … 2,4-diaminopyrimidine 3-n-oxide ... 2,4-pyrimidinediamine, 3-oxide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Erenumab

Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines. Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the first and only...
Approved
Investigational
Matched Products: … KUZELVA 70 MG ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …

Galcanezumab

Galcanezumab is a humanized monoclonal antibody developed by Eli Lilly and Company against human calcitonin gene-related peptide (CGRP). Although several small-molecule CGRP receptor antagonists have been developed, humanized monoclonal antibodies like galcanezumab are specifically designed to selectively bind to CGRP entities with high potency. Given this target specificity, lack of...
Approved
Investigational
Matched Products: … EMGALİTY 120 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET ... EMGALİTY 120 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 3 ADET ... EMGALİTY 100 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 3 ADET …

Testosterone undecanoate

Testosterone undecanoate is the ester prodrug of testosterone and has a mid-chain fatty acid at the carbon 17β position. It was developed via fatty acid esterification of testosterone in order to achieve orally administer testosterone. There are oral and intramuscular formulations available for testosterone undecanoate: both formulations are indicated for...
Approved
Investigational
Matched Iupac: … 9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1- …
Matched Products: … NEBIDO 250 MG/ML IM ENJEKSIYONLUK COZELTI ICEREN FLAKON, 1 ADET ... UROMAX® 1000MG/4 ML SOLUCIÓNINYECTABLE ... Nebido 1000 mg/4 ml Injektionslösung …

Iodine

Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]
Approved
Investigational
Matched Mixtures name: … BION 3 FILM COATED TABLET ... Vitamin & Mineral Formula 1 Dietary Supplement ... New Chapter's D'adamo 4 Your Type Multiple for Type O …
Matched Products: … Varol 1% Liquid ... BIOSPRAY 1% SOLUTION …

Trypan blue free acid

Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence of a mature cataract. This is done to aid in visualization before creating the continuous curvilinear capsulorhexis.
Approved
Matched Iupac: … 5-amino-3-[(E)-2-{4'-[(E)-2-(8-amino-1-hydroxy-3,6-disulfonaphthalen-2-yl)diazen-1-yl]-3,3'-dimethyl- ... [1,1'-biphenyl]-4-yl}diazen-1-yl]-4-hydroxynaphthalene-2,7-disulfonic acid …
Matched Salts cas: … 72-57-1 …

Crotamiton

Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only. It is a colorless to slightly yellowish oil, having a faint amine-like odor. It is miscible with alcohol and with methanol.
Approved
Matched Products: … DERMITON % 10 LOSYON, 1 ŞIŞE …

Dyphylline

Dyphylline is a theophylline derivative with broncho- and vasodilator properties. It is typically used in the management of asthma, cardiac dyspnea, and bronchitis.
Approved
Matched Synonyms: … (1,2-dihydroxy-3-propyl)thiophyllin …
Matched Products: … DIFILIN 300 MG/ 3 ML I.M. ENJEKSİYONLUK ÇÖZELTİ, 100 AMPUL ... DIFILIN 300 MG/ 3 ML I.M. ENJEKSİYONLUK ÇÖZELTİ, 200 AMPUL ... DIFILIN 300 MG/ 3 ML I.M. ENJEKSİYONLUK ÇÖZELTİ, 50 AMPUL …

Altretamine

An alkylating agent proposed as an antineoplastic. It also acts as a chemosterilant for male houseflies and other insects.
Approved
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Bictegravir

Bictegravir is a recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 infection. It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet.
Approved
Investigational
Matched Description: … a recently approved investigational drug that has been used in trials studying the treatment of HIV-1 ... It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet. …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …

Efalizumab

Humanized IgG1 kappa isotype monoclonal antibody that binds to human CD11a. Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin. The FDA approved efalizumab in 2003. It was later withdrawn...
Approved
Investigational
Withdrawn

Alclofenac

Alclofenac is a non-steroidal anti-inflammatory drug. It was withdrawn from the market in the United Kingdom in 1979.
Approved
Withdrawn
Matched Synonyms: … (4-Allyloxy-3-chlorphenyl)essigsäure ... [4-(allyloxy)-3-chlorophenyl]acetic acid ... 3-Chloro-4-(2-propenyloxy)benzeneacetic acid …
Matched Iupac: … 2-[3-chloro-4-(prop-2-en-1-yloxy)phenyl]acetic acid …

Ledipasvir

Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Iupac: … methyl N-[(2S)-1-[(6S)-6-[4-(9,9-difluoro-7-{2-[(1R,3S,4S)-2-[(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl ... [2.4]heptan-5-yl]-3-methyl-1-oxobutan-2-yl]carbamate ... ]-2-azabicyclo[2.2.1]heptan-3-yl]-1H-1,3-benzodiazol-5-yl}-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro …
Matched Description: … Approved in October 2014 by the FDA, Harvoni is indicated for the treatment of HCV genotypes 1, 4, 5, ... HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... first line therapy option in combination with [sofosbuvir] for the treatment of HCV genotypes 1a, 1b, 4, …

Etilefrine

Etilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors. It has been used as a vasoconstrictor agent.
Approved
Withdrawn
Matched Iupac: … 3-[2-(ethylamino)-1-hydroxyethyl]phenol …
Matched Description: … Etilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors …
Matched Categories: … Adrenergic beta-1 Receptor Agonists …

Ethyl ferulate

Approved
Experimental
Matched Synonyms: … Ethyl 4'-hydroxy-3'-methoxycinnamate …
Matched Iupac: … ethyl (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate …

Phentermine

Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug.[A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine. Phentermine has not been reported an addictive potential which allows this agent to...
Approved
Illicit
Matched Iupac: … 2-methyl-1-phenylpropan-2-amine …
Matched Salts cas: … 1197-21-3 …

Phenyl salicylate

Phenyl salicylate is a 2-hydroxybenzoic acid phenyl ester. It is utilized in some manufacturing processes of polymers, lacquers, adhesives, waxes, as well as polishes. It is an active ingredient in some pharmaceutical products as a mild analgesic for pain relief by releasing salicylate (found in DB00945 ). Phenyl salicylate may...
Approved
Matched Mixtures name: … ยาเม็ดตกเบ็ด 4. …

Enprofylline

Enprofylline is a derivative of theophylline which shares bronchodilator properties. Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy. Long-term enprofylline administration may be associated with elevation in liver enzyme levels and unpredictable blood levels.
Approved
Experimental
Matched Synonyms: … 3-n-propylxanthine ... 3-propylxanthine ... 3-Propyl-3,7-dihydro-purine-2,6-dione …
Matched Iupac: … 3-propyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione …

Cocaine

An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of...
Approved
Illicit
Matched Synonyms: … methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate ... [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester …
Matched Iupac: … methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate …
Matched Salts cas: … 53-21-4 …
Matched Products: … PMS-cocaine Hydrochloride Topical Sol 4% …
Displaying drugs 426 - 450 of 12317 in total