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Displaying drugs 426 - 450 of 1642 in total
Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. In August 2017, a combination antibacterial therapy under the market name vabomere...
Approved
Investigational
Matched Description: … Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. ... It is active against Gram-positive and Gram-negative bacteria. ... Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis …
Matched Categories: … meropenem and vaborbactam …
Matched Products: … Meropenem and Sodium Chloride ... Meropenem for Injection USP and Sodium Chloride Injection USP …
C-101, also called Myodur, is developed for the treatment of Duchenne’s muscular dystrophy (DMD) which is a morbid genetic disease that can lead to death in late adolescence due to accelerated skeletal muscle breakdown. C-101 includes a carnitine carrier molecule and a leupeptin analogue, a known calpain inhibitor. Calpain is...
Investigational
Matched Name: … L-aminocarnityl-succinyl-leucyl-argininal-diethylacetal …
Matched Description: … C-101 includes a carnitine carrier molecule and a leupeptin analogue, a known calpain inhibitor. …
Prezatide is a tripeptide consisting of glycine, histidine, and lysine which readily forms a complex with copper ions . Prezatide is used in cosmetic products for the skin and hair. It is known to aid wound healing and its potential applications in chronic obstructive pulmonary disease and metastatic colon cancer...
Experimental
Matched Synonyms: … Growth-modulating peptide (human) ... Glycyl-L-histidyl-L-lysine ... Gly-His-Lys
Matched Description: … Prezatide is used in cosmetic products for the skin and hair. ... and metastatic colon cancer are currently being investigated. ... Prezatide is a tripeptide consisting of glycine, histidine, and lysine which readily forms a complex …
Matched Categories: … Amino Acids, Peptides, and Proteins …
D-3082-L is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide (SLP) vaccine ISA101b.
Investigational
Matched Synonyms: … Human Papilloma Virus (HPV) Type 16 E6/e7 Synthetic Long Peptide (SLP) Vaccine Component D-3082-L ... ISA101 component D-3082-L ... ISA101B component D-3082-L
Matched Name: … D-3082-L
Matched Description: … D-3082-L is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide …
Zalutumumab is a fully human IgG1 monoclonal antibody designed to bind with selectivity to the epidermal growth factor receptor (EGFR). Zalutumumab has been investigated for the treatment of Squamous Cell Cancer and Head and Neck Cancer.
Investigational
Matched International brands: … HuMax-EGFR ... HuMax-EGFR-2F8 ... HuMax-EGFR, 2F8 …
Matched Description: … Zalutumumab has been investigated for the treatment of Squamous Cell Cancer and Head and Neck Cancer. ... Zalutumumab is a fully human IgG1 monoclonal antibody designed to bind with selectivity to the epidermal …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Eflornithine is an irreversible ornithine decarboxylase inhibitor originally developed as a treatment for human African trypanosomiasis. Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells.[A4112, A262834] Additionally, ornithine decarboxylase is activated by c-myc or...
Approved
Withdrawn
Matched Synonyms: … 2-(difluoromethyl)ornithine
Matched Description: … for human African trypanosomiasis. ... hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells. ... [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA …
Matched Categories: … Ornithine Decarboxylase Inhibitors ... Amino Acids, Peptides, and Proteins ... Agents Against Leishmaniasis and Trypanosomiasis ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
Approved
Vet approved
Matched Mixtures name: … Ana-Lex ... Otizol HC Liq ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate …
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … American Safety and First Aid …
Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics.[A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as Pseudomonas aeruginosa, and is also indicated...
Approved
Investigational
Matched Description: … Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against ... [A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused ... by multi-resistant microorganisms such as _Pseudomonas aeruginosa_, and is also indicated for the empirical …
Matched Categories: … cefepime and amikacin …
Matched Products: … Cefepime Hydrochloride and Dextrose …
Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient quantities of the...
Approved
Matched Synonyms: … LT4 ... L-T4 ... L-Thyroxine …
Matched Description: … [F4633] Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily ... a ratio of T4 to T3 of 4.2:1, which is significantly lower than the 14:1 ratio of secretion by the human ... produce sufficient quantities of the thyroid hormones T4 (tetraiodothyronine or thyroxine) and
Matched Mixtures name: … Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... levothyroxine sodium and iodine compounds ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … L THYROX HEXAL 25 ... L THYROX HEXAL 50 ... L THYROX HEXAL 75 …
Investigational
Matched Synonyms: … Recombinant human highly phosphorylated alpha-L-iduronidase …
Investigational
Matched Synonyms: … Haem arginate
Matched Name: … Heme arginate
Matched Categories: … Amino Acids, Peptides, and Proteins …
L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide (SLP) vaccine ISA101b.
Investigational
Matched Synonyms: … Human Papilloma Virus (HPV) Type 16 E6/E7 Synthetic Long Peptide (SLP) Vaccine Component L-3972-T ... ISA101B component L-3972-T …
Matched Name: … L-3972-T …
Matched Description: … L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide …
RGX-111 is an adeno-associated virus vector AAV9 designed to deliver the α-L-iduronidase (IDUA) gene. Developed by REGENXBIO Inc., it was investigated for the treatment of mucopolysaccharidosis Type I (MPS I).
Investigational
Matched Synonyms: … Adeno-associated virus vector serotype 9 expressing human a-L-iduronidase …
Matched Description: … RGX-111 is an adeno-associated virus vector AAV9 designed to deliver the α-L-iduronidase (IDUA) gene. …
Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and cardiogenic shock.[A15638,L33160] Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising...
Approved
Investigational
Matched International brands: … Proternol L
Matched Description: … anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and ... [A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and ... found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising the heart rate and
Matched Categories: … Adrenergic and Dopaminergic Agents ... isoprenaline and other drugs for obstructive airway diseases …
Matched Products: … Isuprel Liq 0.5% ... Isuprel Liq Inh 0.5% ... Isuprel Liq 0.2mg/ml …
Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.
Approved
Vet approved
Matched Description: … Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. ... [A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally ... [A192444] Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity. …
Matched Mixtures name: … Marbeta L Kit ... Marbeta L Kit ... Clotrimazole and Betamethasone Dipropionate …
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... betamethasone and mydriatics ... betamethasone and antiseptics ... betamethasone and antibiotics …
Matched Products: … Betnesol Eye and Ear Drops ... Betnesol Eye and Ear Drops 0.1% ... Betnovate Lot 0.1% …
Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. Darunavir is being...
Approved
Matched Description: … [A191682] Clinical trials are underway and are expected to conclude in August 2020.[L12066] …
Matched Categories: … darunavir and ritonavir ... darunavir and cobicistat ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... emtricitabine, tenofovir alafenamide, darunavir and cobicistat …
Matched Products: … Darunavir 600 and 800 mg …
Experimental
Matched Synonyms: … N3,N4-dimethyl-L-arginine
Matched Categories: … Amino Acids, Peptides, and Proteins …
Levonorgestrel (LNG) is a synthetic progestogen similar to Progesterone used in contraception and hormone therapy.[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. Some of these devices...
Approved
Investigational
Matched Description: … Levonorgestrel (LNG) is a synthetic progestogen similar to [Progesterone] used in contraception and hormone ... Some of these devices are known as Jaydess, Kyleena, and Mirena. ... [A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as …
Matched Mixtures name: … Amethia Lo ... Amethia Lo ... camrese Lo
Matched Categories: … levonorgestrel and estrogen ... levonorgestrel and estrogen ... Genito Urinary System and Sex Hormones ... levonorgestrel and ethinylestradiol ... levonorgestrel and ethinylestradiol …
Matched Products: … ONE-AND-ONE …
Investigational
Matched Synonyms: … Des-(2-7)-human insulin-like growth factor ii fusion protein with glycyl-l-alanyl-l-prolyl-human lysosomal …
Kanamycin (also known as kanamycin A) is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections. Kanamycin is isolated from the bacterium Streptomyces kanamyceticus and its most commonly used form is kanamycin sulfate.
Approved
Investigational
Vet approved
Matched International brands: … Kancin-L
Matched Description: … intramuscular forms, and used to treat a wide variety of infections. ... known as kanamycin A) is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and ... Kanamycin is isolated from the bacterium Streptomyces kanamyceticus and its most commonly used form is …
Matched Mixtures name: … KANCIN-L
Matched Categories: … Alimentary Tract and Metabolism …
Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from...
Approved
Matched Synonyms: … 125-L-serine-2-133-interleukin 2 (human reduced) ... Recombinant human interleukin-2 ... Recombinant interleukin-2 human
Matched Description: … Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression ... clone encodes a modified human interleukin-2. ... recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties. Having been developed in the 1980s by GlaxoSmithKline and approved by the US FDA since January 1991, ondansetron has...
Approved
Withdrawn
Matched Description: … cisplatin, and has reported anxiolytic and neuroleptic properties. ... Commonly formulated as oral tablets, orally disintegrating tablets (ODT), and injections, and available ... ondansetron has demonstrated a long history of use and efficacy. …
Matched Categories: … Antiemetics and Antinauseants …
Matched Products: … Ondansetron and Dextrose ... Ondansetron Hydrochloride and Dextrose ... Ondansetron hydrochloride and dextrose …
Timbetasin is under investigation in clinical trial NCT05555589 (Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2).
Investigational
Matched Synonyms: … 3,11,25,31,38-pentakis(de-n6-acetyl)-1,22,30,33-tetrakis(de-o3-phosphono)thymosin .beta.4(human) ... N-ACETYL-L-SERYL-L-ASPARTYL-L-LYSYL-L-PROLYL-L-ASPARTYL-L-METHIONYL-L-ALANYL-L-GLUTAMYL-L-ISOLEUCYL-L-GLUTAMYL-L-LYSYL-L-PHENYLALANYL-L-ASPARTYL-L-LYSYL-L-SERYL-L-LYSYL-L-LEUCYL-L-LYSYL-L-LYSYL-L-THEONYL-L-GLUTAMYL-L-THEONYL-L-GLUTAMINYL-L-GLUTAMYL-L-LYS ... -ASPARTYL-L-LYSYL-L-SERYL-L-LYSYL-L-LEUCYL-L-LYSYL-L-LYSYL-L-THREONYL …
Matched Description: … Timbetasin is under investigation in clinical trial NCT05555589 (Assessment of the Safety and Efficacy …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Experimental
Matched Synonyms: … Insulin argine
Matched Name: … Insulin argine
Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and Acute Renal Failure. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy. As of December 21, 2017 the FDA approved La Jolla Pharmaceutical's...
Approved
Investigational
Matched Synonyms: … 5-L-isoleucineangiotensin II ... Human angiotensin II ... Angiotensin II (human) …
Matched Description: … and death within hours, no matter young or o ld. ... The novelty of the medication lies in the fact that it is the first and only use of synthetic human angiotensin ... As of December 21, 2017 the FDA approved La Jolla Pharmaceutical's Giapreza (angiotensin II) Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Displaying drugs 426 - 450 of 1642 in total