Displaying drugs 426 - 450 of 12928 in total
Cresol
Cresol is a hydroxytoluene that can be extracted naturally from coal tar or made synthetically. Pure cresol is a mixture of ortho-, meta-, and para- isomers. Cresols are precursors or synthetic intermediates to various other compounds and materials, including plastics, pesticides, pharmaceuticals, disinfectants, and dyes. Ingestion of cresol induces toxicity...
Approved
Matched Description: … Ingestion of cresol induces toxicity in humans and can lead to burning of the mouth and throat, abdominal ... Pure cresol is a mixture of ortho-, meta-, and para- isomers. …
Phalaris arundinacea pollen
Phalaris arundinacea pollen is the pollen of the Phalaris arundinacea plant. Phalaris arundinacea pollen is mainly used in allergenic testing.
Approved
Matched Description: … Phalaris arundinacea pollen is the pollen of the Phalaris arundinacea plant. …
Matched Mixtures name: … Mixture of Twenty-Two Standardized and Non-Standardized Grasses …
Matched Mixtures name: … Mixture of Twenty-Two Standardized and Non-Standardized Grasses …
Secale cereale pollen
Secale cereale pollen is the pollen of the Secale cereale plant. Secale cereale pollen is mainly used in allergenic testing.
Approved
Matched Description: … Secale cereale pollen is the pollen of the Secale cereale plant. …
Matched Mixtures name: … Mixture of Twenty-Two Standardized and Non-Standardized Grasses …
Matched Mixtures name: … Mixture of Twenty-Two Standardized and Non-Standardized Grasses …
Fidaxomicin
Fidaxomicin is a novel macrolide antibiotic used in the treatment of diarrhea caused by Clostridioides (formerly Clostridium) difficile in adult and pediatric patients over the age of 6 months. Fidaxomicin is a naturally-occurring 18-member macrocycle derived from fermentation. Because fidaxomicin contains an 18-membered lactone ring in its structure, it is...
Approved
Matched Description: … of fidaxomicin. ... diarrhea in adult patients over the age of 18. ... patients over the age of 6 months in the treatment population. …
Oxetacaine
Oxetacaine, also called oxethazaince, is a potent surface analgesic with the molecular formula N, N-bis-(N-methyl-N-phenyl-t-butyl-acetamide)-beta-hydroxyethylamine that conserves its unionized form at low pH levels. Its actions have shown to relieve dysphagia, relieve pain due to reflux, chronic gastritis, and duodenal ulcer. Oxetacaine is approved by Health Canada since 1995 for...
Approved
Investigational
Matched Description: … [L1113] It is also in the list of approved derivatives of herbal products by the EMA.[L2816] …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Trazodone
Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor inhibitor (SNRIs) in the...
Approved
Investigational
Matched Description: … triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of ... [T646] A unique feature of this drug is that it does not promote the anxiety symptoms, sexual symptoms ... reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor inhibitor (SNRIs) in the treatment of …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Purslane
Purslane is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Dermatophagoides farinae
Dermatophagoides farinae extracts are sterile solutions used for intradermal testing or subcutaneous immunotherapy. This combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.
Approved
Matched Mixtures name: … Mixture of Standardized Mites ... Allergenic Extract Mixture Of Standardized Mites (5,000 Au/ml) ... Allergenic Extract Mixture Of Standardized Mites (15,000 Au/ml) …
Pentoxyverine
Pentoxyverine, also referred to as carbetapentane, is a non-opioid central acting antitussive with antimuscarinic, anticonvulsant , and local anesthetic properties. It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and H1-receptor antagonists . Pentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors.
The...
Approved
Investigational
Withdrawn
Matched Description: … [L43942] Other forms of pentoxyverine citrate continue to be marketed. ... The FDA withdrew the use of all oral gel drug products containing pentoxyverine citrate. …
Fluvoxamine
Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder.
Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised...
Approved
Investigational
Matched Description: … As of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine. ... Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised of …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Emtricitabine
Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults or combined with tenofovir alafenamide for the prevention of HIV-1 infection in high risk adolescents and adults. Emtricitabine is a cytidine analogue. The drug works by inhibiting HIV reverse transcriptase, preventing transcription of...
Approved
Investigational
Matched Iupac: … 5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-4-imino-1,4-dihydropyrimidin-2-ol …
Matched Description: … Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV ... infection in adults[L9019] or combined with [tenofovir alafenamide] for the prevention of HIV-1 infection ... [L9019] The drug works by inhibiting HIV reverse transcriptase, preventing transcription of HIV RNA to …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Antivirals used in combination for the treatment of HIV infections …
Matched Description: … Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV ... infection in adults[L9019] or combined with [tenofovir alafenamide] for the prevention of HIV-1 infection ... [L9019] The drug works by inhibiting HIV reverse transcriptase, preventing transcription of HIV RNA to …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Antivirals used in combination for the treatment of HIV infections …
Budesonide
Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532]
Budesonide was granted FDA approval on 14 February 1994. It is also available in a combination product...
Approved
Matched Description: … of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis. ... Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions …
Cortisone acetate
Cortisone acetate was first isolate in 1935 and became more widely researched in 1949. Since then, glucocorticoids such as cortisone acetate have been used to treat a number of inflammatory conditions such as endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, and gastrointestinal diseases and disorders.[A226300,L13203]
Cortisone acetate...
Approved
Investigational
Matched Description: … [A226295] Since then, glucocorticoids such as cortisone acetate have been used to treat a number of inflammatory …
Sotrovimab
Sotrovimab (VIR-7831), also known as GSK4182136, is a monoclonal antibody that can neutralize the SARS-CoV-2 virus. Sotrovimab was initially been granted emergency use authorization (EUA) to treat mild-to-moderate COVID-19 on May 26, 2021, based on interim results from a clinical trial, where sotrovimab was found to reduce the risk of...
Approved
Investigational
Matched Description: … 2021, based on interim results from a clinical trial, where sotrovimab was found to reduce the risk of …
Propolis wax
Propolis wax is naturally produced by honeybees by mixing the resin or exudate collected from tree buds, sap flows, or other botanical sources with beeswax that contains fatty acids and bee enzymes. Propolis itself contains various chemical compounds including flavonoids, terpenoids, aldehydes, aromatic acids, aliphatic alcohols and ethers, amino acids,...
Approved
Matched Mixtures name: … Dr.bro MAN OF SENSE Mans Cleanser …
Ivosidenib
Ivosidenib is a first-in-class isocitrate dehydrogenase-1 (IDH1) inhibitor. IDH1 is an enzyme that is often mutated and overexpressed in some cancers, leading to aberrant cell growth and proliferation. Ivosidenib inhibits mutated IDH1, blocking the enzymatic activity and further differentiation of cancer cells. Ivosidenib was granted accelerated approval by the FDA...
Approved
Investigational
Matched Description: … relapsed of refractory acute myeloid leukemia in adults. ... [A248745]
Ivosidenib was granted accelerated approval by the FDA in July 2018 for the treatment of ... A248750] Ivosidenib inhibits mutated IDH1, blocking the enzymatic activity and further differentiation of …
Vaborbactam
Vaborbactam is a β-lactamase inhibitor based on a cyclic boronic acid pharmacophore. It has been used in trials investigating the treatment of bacterial infections in subjects with varying degrees of renal insufficiency. In August 2017, a combination antibacterial therapy under the market name Vabomere was approved by the FDA for...
Approved
Investigational
Matched Iupac: … 2-[(3R,6S)-2-hydroxy-3-[2-(thiophen-2-yl)acetamido]-1,2-oxaborinan-6-yl]acetic acid …
Matched Description: … Vaborbactam is a β-lactamase inhibitor based on a cyclic boronic acid pharmacophore. ... varying degrees of renal insufficiency. ... Vabomere consists of vaborbactam and [Meropenem] for intravenous administration. …
Matched Description: … Vaborbactam is a β-lactamase inhibitor based on a cyclic boronic acid pharmacophore. ... varying degrees of renal insufficiency. ... Vabomere consists of vaborbactam and [Meropenem] for intravenous administration. …
Dermatophagoides pteronyssinus
Dermatophagoides pteronyssinus extracts are sterile solutions used for intradermal testing or subcutaneous immunotherapy. This combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.
Approved
Matched Mixtures name: … Mixture of Standardized Mites ... Allergenic Extract Mixture Of Standardized Mites (5,000 Au/ml) ... Allergenic Extract Mixture Of Standardized Mites (15,000 Au/ml) …
Ulobetasol
Ulobetasol is a highly potent corticosteroid. It is structurally related to clobetasol. Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.[L15047,L15052,L15102]
Ulobetasol was granted FDA approval on 17 December 1990.
Approved
Matched Description: … [A215597] Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis …
Citalopram
Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Matched Description: … SSRIs) widely used to treat the symptoms of depression. ... Citalopram is an antidepressant belonging to the class of selective _serotonin-reuptake inhibitors_ ( ... [A261316]
Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Tyrothricin
Tyrothricin is an antibiotic peptide complex produced and extracted from the aerobic Gram-positive bacillus Brevibacillus parabrevis [L4019, L4021, A32851] which was previously categorized as Bacillus brevis and Bacillus aneurinolyticus . This complex is a mixture comprised of 60% tyrocidine cationic cyclic decapeptides (consisting largely of the six predominant tyrocidines, TrcA/A1,...
Approved
Matched Description: … This complex is a mixture comprised of 60% tyrocidine cationic cyclic decapeptides (consisting largely ... of the six predominant tyrocidines, TrcA/A1, TrcB/B1, TrcC/C1, and other more minor contributors) and ... microbial resistance during the over 60 years of therapeutic use the complex has provided [A36360]. …
Chlorobutanol
Chlorobutanol, or chlorbutol, is an alcohol-based preservative with no surfactant activity . It also elicits sedative-hypnotic and weak local anesthetic actions in addition to antibacterial and antifungal properties. Similar in nature to chloral hydrate, it is formed by the simple nucleophilic addition of chloroform and acetone.
As a long-term stabilizer...
Approved
Investigational
Vet approved
Matched Iupac: … 1,1,1-trichloro-2-methylpropan-2-ol …
Matched Description: … of 0.5%. ... Due to the long terminal half-life of 37 days, the use of chlorobutanol as a sedative is limited because ... of the considerable accumulation which will occur following multiple dosing [A32743]. …
Matched Description: … of 0.5%. ... Due to the long terminal half-life of 37 days, the use of chlorobutanol as a sedative is limited because ... of the considerable accumulation which will occur following multiple dosing [A32743]. …
Nabumetone
Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
Matched Description: … [label,A178903] The molecule itself is a pro-drug with its 6-methoxy-2-naphthylacetic acid (6-MNA) metabolite ... [label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate ... [A179077] While slightly reduced, possibly due to a degree of cyclooxygenase-2 selectivity (COX-2), nabumetone …
Chymotrypsin
Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and polypeptides. It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. Like most proteolytic enzymes, chymotrypsin is activated from its inactive zymogen precursor, chymotrypsinogen, in presence...
Approved
Vet approved
Matched Description: … Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins ... enzymes, chymotrypsin is activated from its inactive zymogen precursor, chymotrypsinogen, in presence of ... Chymotrypsin is the most abundant pancreatic proteases that represent up to 10-20% of the total protein …
Displaying drugs 426 - 450 of 12928 in total