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Displaying drugs 4551 - 4575 of 5418 in total
Edecesertib is under investigation in clinical trial NCT05629208 (Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)).
Investigational
Matched Synonyms: … 3-Pyridinecarboxamide, 4-[[(1R)-1-cyanoethyl]amino]-6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)-N-[(2R)-2 ... 4-{[(1R)-1-cyanoethyl]amino}-6-(3-cyanopyrrolo[1,2- b]pyridazin-7-yl)-N-[(2R)-2-fluoro-3-hydroxy-3- methylbutyl …
Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin. Typically prescribed for the management of diabetes mellitus,...
Approved
Investigational
Matched Description: … of hyperglycemia caused by Type 1 and Type 2 Diabetes. ... build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening ... an onset of action in 1 to 3 hours, duration of action up to 24 hours, and peak action from 6 to 8 hours …
Matched Mixtures name: … Humulin 10/90 Inj ... Humulin 10/90 Inj ... Humulin 10/90 Cartridge …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … HUMULIN NORMAL F PEN AMP ... INSUMAN COMB 15 100 IE/ML ... HUMULIN R 100 IU/ML ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Valaciclovir (valacyclovir), also known as Valtrex, is an antiviral drug that has been used to manage and treat various herpes infections for more than 2 decades. It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline . Valacyclovir is the L-valine ester of aciclovir. It...
Approved
Investigational
Matched Synonyms: … L-Valine, 2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl ester …
Matched Description: … and treat various herpes infections for more than 2 decades. ... This class of drugs forms an important part of hepatitis, HIV, and cytomegalovirus drug regimens [A175900 ... It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline [L5671]. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Acyclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors ... Amino Acids
Matched Products: … Ag-valacyclovir ... Apo-valacyclovir ... VALACICLOVIR 1 G …
Experimental
Matched Synonyms: … Carbobenzoxy-Pro-Lys-Phe-Y(Po2)-Ala-Pro-Ome …
Matched Name: … Methyl N-{[(1R)-1-({1-[(benzyloxy)carbonyl]-L-prolyl-6-ammonio-L-norleucyl}amino)-2-phenylethyl](hydroxy …
Matched Iupac: … ]({[(2S)-1-[(2S)-2-(methoxycarbonyl)pyrrolidin-1-yl]-1-oxopropan-2-yl]amino})phosphinic acid ... [(1R)-1-[(2S)-6-azaniumyl-2-{[(2S)-1-[(benzyloxy)carbonyl]pyrrolidin-2-yl]formamido}hexanamido]-2-phenylethyl …
Experimental
Matched Name: … 2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHANESULFONAMIDE …
Matched Iupac: … 2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(morpholin-4-yl)-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl]ethane ... -1-sulfonamide …
5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR) is an intermediate in the generation of inosine monophosphate and analog of adenosine monophosphate (AMP) that is capable of stimulating AMP-dependent protein kinase (AMPK) activity. AICAR has been used clinically to treat and protect against cardiac ischemic injury. The drug was first used in the 1980s as...
Experimental
Investigational
Matched Synonyms: … 1-(5'-phosphoribosyl)-5-amino-4-imidazolecarboxamide ... 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide …
Matched Iupac: … acid ... {[(2R,3S,4R,5R)-5-(5-amino-4-carbamoyl-1H-imidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic …
Matched Description: … monophosphate and analog of adenosine monophosphate (AMP) that is capable of stimulating AMP-dependent ... The drug was first used in the 1980s as a method to preserve blood flow to the heart during surgery and ... AICAR has been used clinically to treat and protect against cardiac ischemic injury. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Heterocyclic Compounds, 1-Ring …
Investigational
Matched Synonyms: … 4-((4-(2-(6-((2r)-2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1h-tetrazol-1-yl)propyl)-3-pyridinyl ... Benzonitrile, 4-((4-(2-(6-((2r)-2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1h-tetrazol-1-yl)propyl …
Matched Iupac: … 4-{[4-(2-{6-[(2R)-2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1H-1,2,3,4-tetrazol-1-yl)propyl]pyridin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Befotertinib is under investigation in clinical trial NCT05007938 (Befotertinib and Icotinib in Treatment-naive Patients With Advanced Egfr-mutant Lung Cancer).
Investigational
Matched Synonyms: … 2-propenamide, n-(2-((2-(dimethylamino)ethyl)methylamino)-4-methoxy-5-((4-(1-(2,2,2-trifluoroethyl)-1h-indol ... N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-(2,2,2-trifluoroethyl)-1h-indol-3-yl) …
Matched Description: … Befotertinib is under investigation in clinical trial NCT05007938 (Befotertinib and Icotinib in Treatment-naive …
Acenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation. Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. Patients...
Approved
Investigational
Matched Synonyms: … 4-Hydroxy-3-(1-(4-nitrophenyl)-3-oxobutyl)-2H-1-benzopyran-2-one ... 4-Hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Iupac: … 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Description: … This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes ... [A188739] Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. ... Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. …
Matched Categories: … Blood and Blood Forming Organs ... Warfarin and isomers ... Vitamin K Antagonists ... Heterocyclic Compounds, 1-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index …
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator...
Approved
Matched Synonyms: … AZT
Matched Iupac: … 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … of nucleic acid chains. ... It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves ... Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia …
Matched Mixtures name: … LAMIVUDINE, NEVIRAPINE AND ZIDOVUDINE TABLETS (150/200/300 mg) ... Lamivudine and Zidovudine ... Lamivudine and Zidovudine …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... zidovudine and lamivudine ... zidovudine, lamivudine and abacavir ... zidovudine, lamivudine and nevirapine ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Matched Products: … APO-ZIDOVUDINE CAPSULE 100 mg ... Retrovir (azt) ... Apo-zidovudine …
Measles virus vaccine live attenuated is a live virus vaccine for simultaneous vaccination against measles, which is a common childhood disease. The vaccine is prepared from the attenuated line of measles virus, derived from Enders' attenuated Edmonston strain and propagated in chick embryo cell culture.
Approved
Investigational
Matched Synonyms: … Measles virus live antigen, A
Matched Description: … prepared from the attenuated line of measles virus, derived from Enders' attenuated Edmonston strain and ... , which is a common childhood disease. ... Measles virus vaccine live attenuated is a live virus vaccine for simultaneous vaccination against measles …
Matched Mixtures name: … SII Measles and Rubella Virus Vaccine live.Attenuated(Freeze-Dried) 1 dose ... SII Measles and Rubella Virus Vaccine live.Attenuated(Freeze-Dried) 10 doses ... MEASLES AND RUBELLA VIRUS VACCINE LIVE …
Matched Products: … Measles Virus Vacc Live Att Freez Dried Inj ... TOZ ICEREN FLAKON, 10 ADET ... SII MEASLES VACCINE LIVE ATTENUATED (FREEZE- DRIED)-10 DOSES …
Experimental
Matched Name: … 4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE …
Matched Iupac: … 4-{[2-(1H-imidazol-5-yl)ethyl]amino}-2-(phenylamino)pyrazolo[1,5-a][1,3,5]triazine-8-carbonitrile …
Experimental
Matched Name: … N-((2-aminopyrimidin-5-yl)methyl)-5-(2,6-difluorophenyl)-3-ethylpyrazolo[1,5-a]pyrimidin-7-amine …
Matched Iupac: … 5-({[5-(2,6-difluorophenyl)-3-ethylpyrazolo[1,5-a]pyrimidin-7-yl]amino}methyl)pyrimidin-2-amine …
Amprenavir is a protease inhibitor used to treat HIV infection.
Approved
Investigational
Matched Synonyms: … (3S)-Tetrahydro-3-furanyl ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl …
Matched Iupac: … (3S)-oxolan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido]-1-phenylbutan-2 …
Matched Description: … Amprenavir is a protease inhibitor used to treat HIV infection. …
Matched Categories: … Amprenavir and Prodrugs ... Heterocyclic Compounds, 1-Ring ... Acids, Acyclic ... Carboxylic Acids
Matched Products: … AGENERASE®CAPSULA 150 MG ... AGENERASE ® SOLUCION ORAL 15 MG/ML. …
Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca.
Experimental
Matched Synonyms: … (S)-2-amino-3-(3-hydroxy-4-oxo-4H-pyridin-1-yl)propanoate …
Matched Iupac: … (2S)-2-amino-3-(3-hydroxy-4-oxo-1,4-dihydropyridin-1-yl)propanoic acid
Matched Description: … Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from _Leucena glauca_. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Heterocyclic Compounds, 1-Ring ... Amino Acids
TAS-106 is a new nucleoside antimetabolite. TAS-106 has demonstrated strong antitumor activity without serious toxicity in nude rat models bearing human tumours .
Investigational
Matched Synonyms: … 4-Amino-1-((2R,3R,4R,5R)-4-ethynyl-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)pyrimidin-2-one …
Matched Name: … TAS-106
Matched Iupac: … 4-amino-1-[(2R,3R,4S,5R)-4-ethynyl-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2 …
Matched Description: … TAS-106 is a new nucleoside antimetabolite. ... TAS-106 has demonstrated strong antitumor activity without serious toxicity in nude rat models bearing …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Heterocyclic Compounds, 1-Ring …
Experimental
Matched Synonyms: … 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ginisortamab is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and Anti Tumor Activity of UCB6114 Administered Intravenously to Participants With Advanced Solid Tumors).
Investigational
Matched Synonyms: … Immunoglobulin g4 (232-proline), anti-(human gremlin 1) (human monoclonal ucb6114 .gamma.4-chain), disulfide …
Matched Description: … and Anti Tumor Activity of UCB6114 Administered Intravenously to Participants With Advanced Solid Tumors ... Ginisortamab is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics …
A histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.
Approved
Matched Synonyms: … N-(4-(6-Methylamino-7-nitro-2-thia-5-aza-6-hepten-1-yl)-2-thiazolylmethyl)-N,N-dimethylamine …
Matched Iupac: … dimethyl[(4-{[(2-{[1-(methylamino)-2-nitroethenyl]amino}ethyl)sulfanyl]methyl}-1,3-thiazol-2-yl)methyl …
Matched Description: … A histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... Heterocyclic Compounds, 1-Ring ... Acid Reducers ... Gastric Acid Lowering Agents …
Matched Products: … Axid Ar ... Apo-nizatidine ... Nizatidine-150
An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Approved
Investigational
Matched Synonyms: … 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one ... 2,3-Dimethyl-1-phenyl-5-pyrazolone …
Matched Iupac: … 1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one …
Matched Description: … An analgesic and antipyretic that has been given by mouth and as ear drops. …
Matched Mixtures name: … Antipyrine and Benzocaine ... Antipyrine and Benzocaine ... Antipyrine and Benzocaine …
Matched Categories: … Analgesics and Anesthetics ... Heterocyclic Compounds, 1-Ring …
Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic disorders, has moved into pre-clinical development. It is developed by MedImmune for the treatment of Allergic Rhinitis.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN EOTAXIN 1) (HUMAN MONOCLONAL CAT-213 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN …
Matched Description: … Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic …
MAX-40279 is under investigation in clinical trial NCT03412292 (MAX-40279 in Subjects With Acute Myelogenous Leukemia (AML)).
Investigational
Matched Synonyms: … 7-(4-Fluoro-2-methoxyphenyl)-6-methyl-N-(1-(piperidin-4-yl)-1H-pyrazol-4-yl) thieno (3,2-d)pyrimidin- …
Matched Iupac: … N-[7-(4-fluoro-2-methoxyphenyl)-6-methylthieno[3,2-d]pyrimidin-2-yl]-1-(piperidin-4-yl)-1H-pyrazol-4- …
Matched Description: … investigation in clinical trial NCT03412292 (MAX-40279 in Subjects With Acute Myelogenous Leukemia (AML
Nipocalimab is under investigation in clinical trial NCT04119050 (Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia).
Investigational
Matched Synonyms: … .-1 chain), disulfide with human monoclonal m281 .lambda.-chain, dimer …
Matched Description: … Nipocalimab is under investigation in clinical trial NCT04119050 (Efficacy and Safety of M281 in Adults …
Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. It is also used in tablet form as a drug to treat hypertension. Timolol was first approved by the FDA in 1978. This drug is marketed by several manufacturers...
Approved
Matched Synonyms: … (S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol …
Matched Iupac: … (2S)-1-(tert-butylamino)-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propan-2-ol …
Matched Description: … of conditions such as open-angle glaucoma and hypertension. ... [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management ... [L6724] It is also used in tablet form as a drug to treat hypertension. …
Matched Salts cas: … 91524-16-2 ... 26921-17-5 …
Matched Mixtures name: … Dorzolamide and Timolol ... Dorzolamide and Timolol ... Dorzolamide HCl and Timolol Maleate …
Matched Categories: … timolol and thiazides ... Beta Blocking Agents and Thiazides ... Antiglaucoma Preparations and Miotics ... timolol, thiazides and other diuretics ... Beta Blocking Agents, Non-Selective, and Thiazides …
Matched Products: … TIMOLOL 0.1% AT 1A PHARMA ... TIMOLOL 0.5% AT 1A PHARMA ... TIMOLOL 0.25% AT 1A PHARMA …
Quinagolide is a non-ergot-derived selective dopamine D2 receptor agonist used for the treatment of elevated levels of prolactin or hyperprolactinaemia. Hyperprolalctinaemia is associated with gonadal dysfunction, including infertility and reduced libido, as well as long-term complications such as osteoporosis . Newer dopamine receptor agonists such as quinagolide and DB00248 are...
Approved
Investigational
Matched Synonyms: … (+-)-N,N-Diethyl-N'-((3R*,4aR*,10aS*)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo(g)quinolin …
Matched Iupac: … (3S,4aS,10aR)-3-[(diethylsulfamoyl)amino]-1-propyl-1H,2H,3H,4H,4aH,5H,10H,10aH-benzo[g]quinolin-6-ol …
Matched Description: … Quinagolide exists as a racemate and its relevant clinical activity is mediated predominantly by the ... Newer dopamine receptor agonists such as quinagolide and [DB00248] are shown to effectively inhibit prolactin ... It is typically present in the hydrochloride salt form and is marketed as oral tablets under the brand …
Matched Categories: … Genito Urinary System and Sex Hormones …
Displaying drugs 4551 - 4575 of 5418 in total