Displaying drugs 451 - 475 of 12915 in total
Methenamine
Methenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).
Approved
Vet approved
Matched Description: … Methenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. …
Matched Salts cas: … 34317-08-3 ... 72962-49-3 …
Matched Mixtures name: … Me NaPhos MB Hyo 1 …
Matched Products: … HIPPURIN 1 GR FILM TABLET, 56 ADET ... HIPPURIN 1 GR FILM TABLET, 28 ADET …
Matched Salts cas: … 34317-08-3 ... 72962-49-3 …
Matched Mixtures name: … Me NaPhos MB Hyo 1 …
Matched Products: … HIPPURIN 1 GR FILM TABLET, 56 ADET ... HIPPURIN 1 GR FILM TABLET, 28 ADET …
Padimate O
Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA . It is a structurally-related compound to DB02362 that absorbs UV-B rays to prevent photodamage. It penetrates human skin, and is shown to induce non-ligatable strand...
Approved
Matched Description: … It is a structurally-related compound to [DB02362] that absorbs UV-B rays to prevent photodamage. …
Matched Mixtures name: … Presun 39 Sunscreen Crm Spf39 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Mixtures name: … Presun 39 Sunscreen Crm Spf39 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer (B.1.351-B.1.1.7 strains)
Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer. It is intended to elicit protection against Omicron XBB.1.5, one of the dominant circulating SARS-CoV-2 subvariants in 2023. It is produced using recombinant DNA technology in CHO cell lines and...
Approved
Matched Description: … Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein ... [L48902,L48907]
Bimervax was issued marketing authorization in the EU in March 2023 for use as a booster …
Profenamine
Profenamine (also known as ethopropazine) is a medication derived from phenothiazine. It is primarily used as an antidyskinetic to treat Parkinsonism. It is sold under the trade name Parsitan in Canada. In the US, the marketing of profenamine has been discontinued.
Approved
Matched Synonyms: … 10-[2-(diethylamino)-1-propyl]phenothiazine ... 2-diethylamino-1-propyl-N-dibenzoparathiazine ... N,N-diethyl-1-(10H-phenothiazin-10-yl)-2-propanamine …
Matched Iupac: … diethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine …
Matched Description: … Profenamine (also known as ethopropazine) is a medication derived from phenothiazine. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Iupac: … diethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine …
Matched Description: … Profenamine (also known as ethopropazine) is a medication derived from phenothiazine. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Betamethasone phosphate
Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible betamethasone to agonize glucocorticoid receptors. Betamethasone provides greater anti-inflammatory activity than prednisolone with less sodium and water retention. Betamethasone sodium phosphate was granted FDA approval on 3 March 1965.
Approved
Vet approved
Matched Iupac: … phenanthren-1-yl]-2-oxoethoxy}phosphonic acid ... 9b-fluoro-1,10-dihydroxy-2,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … [L11994] Betamethasone sodium phosphate was granted FDA approval on 3 March 1965.[L11994] ... Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible [betamethasone …
Matched Description: … [L11994] Betamethasone sodium phosphate was granted FDA approval on 3 March 1965.[L11994] ... Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible [betamethasone …
Methylphenobarbital
A barbiturate that is metabolized to phenobarbital. It has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital.
Approved
Matched Synonyms: … 1-Methylphenobarbital ... 5-ethyl-1-methyl-5-phenylbarbituric acid ... 5-Ethyl-1-methyl-5-phenyl-pyrimidine-2,4,6-trione …
Matched Iupac: … 5-ethyl-1-methyl-5-phenyl-1,3-diazinane-2,4,6-trione …
Matched Description: … A barbiturate that is metabolized to phenobarbital. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 5-ethyl-1-methyl-5-phenyl-1,3-diazinane-2,4,6-trione …
Matched Description: … A barbiturate that is metabolized to phenobarbital. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Doripenem
Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that...
Approved
Investigational
Matched Iupac: … (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-3-{[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3- ... yl]sulfanyl}-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid …
Matched Description: … Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen ... found that doripenem carried an increased risk of death and lower clinical cure rates, resulting in a ... The FDA revised the doripenem label in 2014 to include a warning against use in ventilator-associated …
Matched Description: … Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen ... found that doripenem carried an increased risk of death and lower clinical cure rates, resulting in a ... The FDA revised the doripenem label in 2014 to include a warning against use in ventilator-associated …
Tezacaftor
Tezacaftor is a drug of the cystic fibrosis transmembrane conductance regulator (CFTR) potentiator class. It was developed by Vertex Pharmaceuticals and FDA approved in combination with ivacaftor to manage cystic fibrosis. This drug was approved by the FDA on February 12, 2018. Cystic Fibrosis is an autosomal recessive disorder caused...
Approved
Investigational
Matched Iupac: … 1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)-N-{1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan ... -2-yl)-1H-indol-5-yl}cyclopropane-1-carboxamide …
Matched Description: … Tezacaftor is a drug of the cystic fibrosis transmembrane conductance regulator (CFTR) potentiator class ... [A20298,A20299] As a result, CF patients produce thick, sticky mucus that clogs the ducts of organs where …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Tezacaftor is a drug of the cystic fibrosis transmembrane conductance regulator (CFTR) potentiator class ... [A20298,A20299] As a result, CF patients produce thick, sticky mucus that clogs the ducts of organs where …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Givosiran
Givosiran is a small interfering RNA (siRNA) directed towards 5-aminolevulinic acid synthase, a critical enzyme in the heme biosynthesis pathway. It is manufactured by Alnylam Pharmaceuticals and was first approved for use in the United States in November 2019 for the treatment of adults with acute hepatic porphyria, a genetic...
Approved
Investigational
Matched Description: … Givosiran is a small interfering RNA (siRNA) directed towards 5-aminolevulinic acid synthase, a critical ... use in the United States in November 2019 for the treatment of adults with acute hepatic porphyria, a ... Givosiran is the second-ever FDA-approved member of the siRNA drug class (the first being [patisiran]), a …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Aminolevulinate Synthase 1-directed RNA Interaction ... Aminolevulinate Synthase 1-Directed Small Interfering RNAs …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Aminolevulinate Synthase 1-directed RNA Interaction ... Aminolevulinate Synthase 1-Directed Small Interfering RNAs …
Ginkgo biloba
Ginkgo biloba extract contains a group of terpene lactones (notably, ginkgolides and diterpenes) and ginkgo flavone glycosides (notably, ginkgetin, bilobetin, and sciadopitysin) that have antioxidant and vasoactive properties. Most of the studies that investigate the effect of ginkgo biloba use the standardized extract of Ginkgo biloba (EGb) 761 (EGb761), which...
Approved
Investigational
Nutraceutical
Matched Description: … Lactones include ginkgolide A, ginkgolide B, ginkgolide C, bilobalide, and ginkgotoxin, a lactone that ... _Ginkgo biloba_ extract contains a group of terpene lactones (notably, ginkgolides and diterpenes) and ... biloba_ use the standardized extract of _Ginkgo biloba_ (EGb) 761 (EGb761), which was developed by a …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … EXTRACTO DE GINKO BILOBA AL 24 % EQUIVALENTE A 9.6 MG DE GLICOSIDOS FLAVONOIDES. …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … EXTRACTO DE GINKO BILOBA AL 24 % EQUIVALENTE A 9.6 MG DE GLICOSIDOS FLAVONOIDES. …
Apadamtase alfa
Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs …
Matched Description: … a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13), which is responsible ... [A262076] Patients with cTTP have a severe deficiency of a plasma metalloproteinase called ADAMTS13 ( ... Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia …
Matched Description: … a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13), which is responsible ... [A262076] Patients with cTTP have a severe deficiency of a plasma metalloproteinase called ADAMTS13 ( ... Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia …
Influenza A virus A/Christchurch/16/2010 NIB-74XP (H1N1) hemagglutinin antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Christchurch/16/2010 NIB-74XP (H1N1) hemagglutinin antigen (formaldehyde inactivated …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …
Chlorothiazide
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
Approved
Vet approved
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Salts cas: … 7085-44-1 …
Matched Salts cas: … 7085-44-1 …
Methacholine
Asthma is a complex condition associated with phenomena such as airway hyperresponsiveness (AHR), in which the smooth muscle in the airways (ASM) excessively contracts in response to stimuli, reducing pulmonary function and causing symptoms such as difficulty breathing.[A229598, A229603] Although the underlying pathology of AHR is complex, ASM contraction can...
Approved
Investigational
Matched Description: … pathology of AHR is complex, ASM contraction can be stimulated by cholinergic agonists that activate M3< ... Asthma is a complex condition associated with phenomena such as airway hyperresponsiveness (AHR), in ... [A229603, A229618, A229643] Methacholine is a non-specific cholinergic agonist (parasympathomimetic) …
Matched Salts cas: … 62-51-1 …
Matched Salts cas: … 62-51-1 …
Durvalumab
Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody and a novel immune-checkpoint inhibitor for cancer treatment. Produced by recombinant DNA technology in Chinese Hamster Ovary (CHO) cell suspension culture, durvalumab is a programmed death-ligand 1 (PD-L1) blocking antibody that works to promote normal immune responses that attack tumour...
Approved
Investigational
Matched Description: … Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody and a novel immune-checkpoint ... programmed death-ligand 1 (PD-L1) blocking antibody that works to promote normal immune responses that ... locally advanced, unresectable non-small cell lung cancer (NSCLC), only if PD-L1 is expressed in ≥ 1% …
Matched Categories: … PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors ... PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors ... Programmed Death Ligand-1 Blocker ... Programmed Death Ligand-1 Antagonists ... Programmed Death Ligand-1-directed Antibody Interactions …
Matched Products: … IMFINZI 120 MG/2.4 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET ... IMFINZI 500 MG/10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET …
Matched Categories: … PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors ... PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors ... Programmed Death Ligand-1 Blocker ... Programmed Death Ligand-1 Antagonists ... Programmed Death Ligand-1-directed Antibody Interactions …
Matched Products: … IMFINZI 120 MG/2.4 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET ... IMFINZI 500 MG/10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET …
Meprednisone
Approved
Investigational
Methylprednisone
Methylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.
Approved
Investigational
Matched Iupac: … 7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-7,10-dione ... (1R,3aS,3bS,5S,9aR,9bS,11aS)-1-hydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H, …
Phentermine
Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug.[A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine. Phentermine has not been reported an addictive potential which allows this agent to...
Approved
Illicit
Matched Iupac: … 2-methyl-1-phenylpropan-2-amine …
Matched Description: … Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity ... A174376, T403] Later on, phentermine was approved alone and in combination with topiramate in 2012 as a …
Matched Salts cas: … 1197-21-3 …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Description: … Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity ... A174376, T403] Later on, phentermine was approved alone and in combination with topiramate in 2012 as a …
Matched Salts cas: … 1197-21-3 …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Influenza A virus A/Singapore/gp1908/2015 IVR-180 (H1N1) hemagglutinin antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Singapore/gp1908/2015 IVR-180 (H1N1) hemagglutinin antigen (MDCK cell derived, propiolactone …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …
Ezogabine
Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine. It is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 trials as an adjunctive treatment for partial-onset seizures in adult patients with refractory epilepsy....
Approved
Investigational
Matched Description: … ) and is currently being studied in Phase 3 trials as an adjunctive treatment for partial-onset seizures ... It is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED ... Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine. …
Melphalan flufenamide
Melphalan flufenamide, also known as melflufen or J1, is a prodrug of melphalan.[A230123,L32173] Melphalan flufenamide is more readily uptaken by cells than melphalan, and is cleaved to the active metabolite by aminopeptidases. In vitro models show that melphalan is 10 to hundreds of times more potent than melphalan. The increased...
Approved
Withdrawn
Matched Iupac: … ethyl (2S)-2-[(2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanamido]-3-(4-fluorophenyl)propanoate …
Matched Description: … It has since been withdrawn from the market in the wake of the phase 3 OCEAN trial which showed a decrease ... Melphalan flufenamide, also known as melflufen or J1, is a prodrug of [melphalan]. ... [A230123] The increased potency makes melphalan flufenamide a treatment option for patients with relapsed …
Matched Description: … It has since been withdrawn from the market in the wake of the phase 3 OCEAN trial which showed a decrease ... Melphalan flufenamide, also known as melflufen or J1, is a prodrug of [melphalan]. ... [A230123] The increased potency makes melphalan flufenamide a treatment option for patients with relapsed …
Tetrofosmin
Tetrofosmin was developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds. It presents a molecular formula of 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane. Tetrofosmin is part of the group of diphosphines. Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.
Approved
Matched Description: … It presents a molecular formula of 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane. ... Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.[A7788] …
Influenza A virus A/California/7/2009(H1N1)-like hemagglutinin antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/California/7/2009(H1N1)-like hemagglutinin antigen (propiolactone inactivated) …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …
Matched Products: … Influenza A (H1N1) 2009 Monovalent Vaccine …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …
Matched Products: … Influenza A (H1N1) 2009 Monovalent Vaccine …
Displaying drugs 451 - 475 of 12915 in total