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Displaying drugs 451 - 475 of 629 in total

Atidarsagene autotemcel

Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC …
Matched Description: … Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Etidronic acid

Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Matched Description: … Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid] ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and ... generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and …
Matched Categories: … etidronic acid and calcium, sequential ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … DIDRONAT 400 MG TABLET, 30 ADET …

Selexipag

Selexipag was approved by the United States FDA on December 22, 2015 for the treatment of pulmonary arterial hypertension (PAH) to delay disease progression and reduce risk of hospitalization. PAH is a relatively rare disease with usually a poor prognosis requiring more treatment options to prolong long-term outcomes. Marketed by...
Approved
Matched Description: … December 22, 2015 for the treatment of pulmonary arterial hypertension (PAH) to delay disease progression and ... Marketed by Actelion Pharmaceuticals under brand name Uptravi, selexipag and its active metabolite, ACT ... act as agonists of the prostacyclin receptor to increase vasodilation in the pulmonary circulation and …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … UPTRAVI 400 MCG ... UPTRAVI 400 MCG FILM KAPLI TABLET, 60 ADET ... Uptravi 400 microgram Film-coated tablets …

Nogapendekin alfa

Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Fusion protein consisting of il-15n72d and il-15rasu/fc …
Matched Description: … 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG ... Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , stimulating the activation and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Dideoxyadenosine

Investigational
Matched Synonyms: … -d-glycero-pentofuranosyl)purine ... -d-glycero-pentofuranosyl)-9h-purin-6-amine …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Quetiapine

Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high...
Approved
Matched Description: … as [clozapine] and [olanzapine]. ... , quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and ... [L8546] Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects …
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Products: … SEROQUEL SR 400MG ... QUETIAPIN ACCORD 400MG ... QUETIAPIN AL 400MG RET …

Belimumab

Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor. BLyS levels are often elevated in immunodeficient and autoimmune disorders, such as systemic lupus erythematosus (SLE).[A251495, L42705] By binding to...
Approved
Matched Description: … [A251520] It is currently used to treat SLE and lupus nephritis.[L42630] ... antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and ... [L42630] BLyS levels are often elevated in immunodeficient and autoimmune disorders, such as systemic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Benlysta Powder for Solution for Infusion 400mg ... BENLYSTA 400 MG POLVO LIOFILIZADO CONCENTRADO PARA SOLUCION PARA INFUSION ... BENLYSTA 400 MG IV INFUZYONLUK COZETI HAZIRLAMAK ICIN TOZ ICEREN FLAKON, 1 ADET …

Mucor circinelloides f. circinelloides

Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. circinelloides …

Diethylene glycol ethyl methyl ether

Experimental
Matched Name: … Diethylene glycol ethyl methyl ether …

Tocilizumab

Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies. Tocilizumab was granted FDA approval on 8 January 2010 to treat a...
Approved
Matched Description: … [L40164] Subsequently, it was granted approval by Health Canada and the FDA in October [L43697] and December ... autoimmune disorders, such as different types of arthritis and cytokine release syndrome. ... Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … ACTEMRA® CONCENTRADO PARA INFUSION 400 MG/20ML ... ACTEMRA 400 MG/20 ML IV INFUZYONLUK COZELTI KONSANTRESI İÇEREN FLAKON, 1 ADET ... ACTEMRA 400 MG/20 ML IV INFUZYONLUK COZELTI KONSANTRESI İÇEREN FLAKON, 4 ADET …

Sorafenib

Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also...
Approved
Investigational
Matched Description: … Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. ... in tumour cell proliferation and tumour angiogenesis. ... It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Sorafenib G.L. 400 mg-Filmtabletten ... Sorafenib Sandoz 400 mg - Filmtabletten …

Gatifloxacin

Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. It was first introduced by Bristol-Myers Squibb in 1999 under the brand name Tequin® for the treatment of respiratory tract infections. Gatifloxacin is available as...
Approved
Investigational
Withdrawn
Matched Description: … It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. ... Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. ... Gatifloxacin is available as tablets and in various aqueous solutions for intravenous therapy. …
Matched Products: … GATFLOX ® 400MG TABLETAS ... STAROX ® TABLETAS RECUBIERTAS 400 MG …

Doxofylline

Doxofylline is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects in animal and human studies. In contrast with other xanthine derivatives, doxofylline does...
Experimental
Matched Description: … doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects in animal and ... Unlike theophylline, doxofylline does not affect calcium influx and does not antagonize the actions of ... xanthine derivatives, doxofylline does not significantly bind to adenosine alpha-1 or alpha-2 receptors and …
Matched Mixtures name: … MUCOFIX 1200/400 MG EFERVESAN TABLET, 10 ADET ... MUCOFIX 1200/400 MG EFERVESAN TABLET, 5 ADET ... MUCOFIX 900/400 MG EFERVESAN TABLET, 10 ADET …
Matched Products: … PUROXAN® TABLETAS 400 MG ... Puroxan (Doxofylline 400mg) Tablet ... DOXOMAX 400 MG EFERVESAN TABLET, 20 ADET …

Theophylline

A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly...
Approved
Matched Description: … Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated ... mainly for asthma, bronchospasm, and COPD. ... methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and …
Matched Mixtures name: … Theophylline 4mg and 5% Dextrose Inj ... Theophylline 1.6mg and 5% Dextrose Inj ... Theophylline 0.8mg and 5% Dextrose Inj …
Matched Categories: … Xanthines and Adrenergics ... theophylline and adrenergics …
Matched Products: … โบรโนเด - 400 ... UNIPHYLLIN 400 ... DURALYN-CR 400 MG …

Budesonide

Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994. It is also available in a combination product...
Approved
Matched Description: … of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis. ... Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions …
Matched Mixtures name: … Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate …
Matched Categories: … Alimentary Tract and Metabolism ... salbutamol and budesonide ... formoterol and budesonide ... salmeterol and budesonide ... formoterol, glycopyrronium bromide and budesonide …
Matched Products: … FRENOLYN 400 UG ... บูเนส-400 เวนติแคป ... BUDOLER 400 MCG İNHALER KAPSÜL (BUDECTON 400 MCG İNHALER KAPSÜL), 60 KAPSÜL …

Glymidine

Glycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and increasing the sensitivity of peripheral tissues to insulin. The mechanism of action of glycodiazine in lowering blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta...
Approved
Investigational
Matched International brands: … Glycanol …
Matched Description: … Glycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and ... appears to be dependent on stimulating the release of insulin from functioning pancreatic beta cells, and ... ATP-sensitive potassium channel receptors on the pancreatic cell surface, reducing potassium conductance and …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Erythromycin

Erythromycin is a bacteriostatic antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics which consists of Azithromycin, Clarithromycin, Spiramycin and others. It was originally discovered in 1952. Erythromycin is widely used for treating a variety of infections, including those...
Approved
Investigational
Vet approved
Matched Description: … antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and ... the macrolide group of antibiotics which consists of [Azithromycin], [Clarithromycin], [Spiramycin] and ... [L5245,L7261] It is available for administration in various forms, including intravenous, topical, and …
Matched Mixtures name: … Erythromycin and Benzoyl Peroxide ... Erythromycin and Benzoyl Peroxide ... Erythromycin and Benzoyl Peroxide …
Matched Categories: … Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … E.E.s 400 ... EryPed 400 ... Ees-400 …

Silver sulfadiazine

Silver sulfadiazine is a sulfa derivative topical antibacterial used primarily on second- and third-degree burns.
Approved
Vet approved
Matched Description: … Silver sulfadiazine is a sulfa derivative topical antibacterial used primarily on second- and third-degree …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … SILVAMED % 1 KREM, 400 G ... SILVERDIN % 1 KREM, 400 G ... SILVADIAZIN % 1 400 GR KREM …

1-Deoxy-1-Thio-Heptaethylene Glycol

Experimental
Matched Name: … 1-Deoxy-1-Thio-Heptaethylene Glycol …

Diglyme

Experimental
Matched Synonyms: … diethylene glycol dimethyl ether …
Matched Categories: … Glycols …

D-alpha-Tocopherol acetate

Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Nutraceutical
Vet approved
Matched Description: … d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and ... At the moment however, there exists a lack of formal data and evidence to support any such additional ... This biologic action of vitamin E consequently continues to generate ongoing interest and study in whether …
Matched Mixtures name: … Duet DHA 400 ... Duet DHA 400 ec ... Multi Vitamin and Mineral vitamin …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … Vitamin E Cap 400iu ... KORDEL`S E 400 IU CAPSULES ... CLEAR BASE VITAMIN E 400 IU CAPSULE …

Ivermectin

Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro­-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). Ivermectin is mainly used in...
Approved
Investigational
Vet approved
Matched Description: … use for the prophylaxis and treatment of COVID-19. ... roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and ... also be effective against other worm infestations (such as strongyloidiasis, ascariasis, trichuriasis and …
Matched Categories: … Scabicides and Pediculicides ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … IVOMEC Injection 1% w/v for Cattle and Sheep …

Fluorescein

A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. It has been approved by FDA for use in externally applied drugs...
Approved
Matched Synonyms: … D and C Yellow No. 7 …
Matched Description: … and corneal trauma. ... It has been approved by FDA for use in externally applied drugs and cosmetics. ... A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline …
Matched Mixtures name: … Minims Lidocaine and Fluorescein ... Fluorescein Sodium and Proparacaine Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride …
Matched Categories: … Indicators and Reagents …

Dextromethorphan

Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]
Approved
Matched Description: … and also a drug of abuse. ... Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant …
Matched Mixtures name: … Up and Up Flu and Severe Cold and Cough Relief ... Daytime Cold and Flu and Nighttime Cold and Flu ... Daytime Cold and Flu and Nighttime Cold and Flu …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives ... bupropion and dextromethorphan …
Matched Products: … Up and Up Cough Suppressant DM ... Up and Up 12 Hour Cough Relief ... Foster and Thrive 12 Hour Cough Relief …

Bevacizumab

There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells.[A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a therapeutic target for anti-cancer...
Approved
Investigational
Matched Description: … [A193272,A193275] It is a humanized monoclonal IgG antibody, and inhibits angiogenesis by binding and ... of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and ... [A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ZİRABEV 400 MG/16 ML İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... ZIRABEV CONCENTRATE FOR SOLUTION FOR INFUSION 400 MG/16 ML ... Avastin Concentrate for Solution for Infusion 400mg/16ml …
Displaying drugs 451 - 475 of 629 in total