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Displaying drugs 451 - 475 of 2637 in total
Lorigerlimab is under investigation in clinical trial NCT05848011 (A Study of Lorigerlimab With Docetaxel or Docetaxel Alone in Participants With Metastatic Castration-resistant Prostate Cancer).
Investigational
Matched Synonyms: … ANTI-(HOMO SAPIENS CTLA4 (CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, CD152)), CHIMERIC, HOMO SAPIENS AND ... MMUNOGLOBULIN G4 SCFV-H-CH2-CH3_SCFV, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD1, PD-1, CD279)) AND
Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
Approved
Withdrawn
Matched Synonyms: … N-benzyl-beta-(isonicotinylhydrazino)propionamide ... N-benzyl-beta-(isonicotinoylhydrazine)propionamide ... 2-(2-(Benzylcarbamoyl)ethyl)hydrazide isonicotinic acid
Matched Iupac: … N-benzyl-3-[(pyridin-4-yl)formohydrazido]propanamide …
Matched Description: … Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing …
Matched Categories: … Acids, Heterocyclic ... Isonicotinic Acids
Cedirogant is under investigation in clinical trial NCT05044234 (A Study to Assess Adverse Events and Disease Activity With Cedirogant (ABBV-157) in Adult Participants With Moderate to Severe Psoriasis).
Investigational
Matched Synonyms: … (1-(2,4-dichloro-3-((7-chloro-5-(trifluoromethyl)-1hindol-1-yl)methyl)benzoyl)piperidin-4-yl)acetic acid ... 4-piperidineacetic acid, 1-(2,4-dichloro-3-((7-chloro-5-(trifluoromethyl)-1h-indol-1-yl)methyl)benzoyl
Matched Description: … Cedirogant is under investigation in clinical trial NCT05044234 (A Study to Assess Adverse Events and
A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Approved
Investigational
Nutraceutical
Matched Synonyms: … (+)-cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric acid ... 5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid ... cis-Hexahydro-2-oxo-1H-thieno(3,4)imidazole-4-valeric acid
Matched Iupac: … 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid
Matched Description: … and milk. ... It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, …
Matched Mixtures name: … Folivane-Plus with Ascorbic Acid Precursors ... B-complex With Vitamin C, Biotin, Folic Acid ... Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA …
Matched Categories: … Enzymes and Coenzymes ... Diet, Food, and Nutrition ... Alimentary Tract and Metabolism …
Matched Products: … Biona-vit Controls and Prevents Hair Loss …
Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Garcinia Cambogia (Constituent of Garcinia Cambogia and Garcinia Indica) …
DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy).
Investigational
Matched Synonyms: … antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal antibody and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood...
Approved
Investigational
Matched Description: … in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone that contains 191 amino acid ... fat mass regulation, blood glucose level regulation, and lipid regulation in both children and adults ... Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Anterior Pituitary Lobe Hormones and Analogues ... Somatropin and Somatropin Agonists …
Matched Products: … ZOMACTON Powder and Solvent for Solution for Injection 10mg ... ZOMACTON Powder and Solvent for Solution for Injection 4 mg ... GENOTROPIN® 12MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating diarrhea. The drug was first synthesized in 1969 and used medically in 1976. It is a highly lipophilic synthetic phenylpiperidine opioid that is structurally similar to opiate receptor agonists such as diphenoxylate and haloperidol. Due to...
Approved
Matched Description: … withdrawal symptoms and to induce euphoria. ... [L42785] The drug was first synthesized in 1969 and used medically in 1976. ... [A6249] Due to pharmacological properties, loperamide has been misused and abused to self-manage opioid …
Matched Mixtures name: … Loperamide Hydrochloride and Simethicone ... Up and Up Anti Diarrheal Anti Gas ... Anti Diarrheal and Anti Gas …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up anti diarrheal ... Berkley and Jensen Anti Diarrheal ... Foster and Thrive Anti-diarrheal …
A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver. Prednisone was granted FDA approval on 21 February 1955.
Approved
Vet approved
Matched Description: … [A187463] It is biologically inert and converted to [prednisolone] in the liver. …
Matched Categories: … Alimentary Tract and Metabolism ... Prednisolone and Prodrugs ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … PREDNISON ACIS 5MG ... PREDNISON ACIS 20MG ... PREDNISON ACIS 50MG …
Investigational
Matched Synonyms: … L-glutamic acid, n-(4-(3-amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo(1,5-f)pteridin-8(9h)-yl)benzoyl)- ... 5,10-methylene-(6rs)-tetrahydrofolic acid ... 5,10-methylenetetrahydrofolic acid
Matched Iupac: … 4-{3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl}phenyl)formamido]pentanedioic acid
Matched Categories: … Enzymes and Coenzymes …
Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen atom. This substance is known to target aspartate carbamoyltransferase catalytic chain and CAD protein.
Experimental
Matched Synonyms: … Acidum sparfosicum ... Sparfosic acid ... N-(phosphonacetyl)-L-aspartic acid
Matched Name: … Sparfosic acid
Matched Iupac: … (2S)-2-(2-phosphonoacetamido)butanedioic acid
Matched Description: … This substance is known to target aspartate carbamoyltransferase catalytic chain and CAD protein. ... Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. ... These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids
One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
Approved
Nutraceutical
Matched Synonyms: … Aspartic acid ... Acidum asparticum ... L-Aspartic acid
Matched Name: … Aspartic acid
Matched Iupac: … (2S)-2-aminobutanedioic acid
Matched Description: … One of the non-essential amino acids commonly occurring in the L-form. ... It is found in animals and plants, especially in sugar cane and sugar beets. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Premasol - sulfite-free (Amino Acid) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic ... Excitatory Amino Acids
Dabocemagene autoficel is an ex vivo, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.
Investigational
Matched Synonyms: … AUTOLOGOUS HUMAN DERMAL FIBROBLAST CELLS DERIVED FROM SKIN BIOPSIES, AND TRANSDUCED WITH A NON-REPLICATING ... INTEGRATED PROVIRAL HUMAN COLLAGEN TYPE VII TRANSGENE COL7A1 PLUS 5'-HUMAN CYTOMEGALOVIRUS PROMOTER/UTR-AND
Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the treatment of pediatric leukemia. In the 1950's its production was discontinued in favor of methotrexate, which is less potent but less toxic. Off label, aminopterin has also been used in the treatment...
Investigational
Withdrawn
Matched Synonyms: … N-(4-(((2,4-diamino-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid ... 4-aminofolic acid ... 4-aminopteroylglutamic acid
Matched Iupac: … (2S)-2-[(4-{[(2,4-diaminopteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid
Matched Description: … Clinicians need to be aware of the characteristic teratologic effects of aminopterin and methotrexate ... Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the …
Matched Categories: … Folic Acid Antagonists …
Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and 50% of...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-Amino-7-isopropyl-5-oxo-5H-(1)benzopyrano(2,3-b)pyridine-3-carboxylic acid
Matched Iupac: … 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid
Matched Description: … Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and ... aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and
Matched Categories: … Alimentary Tract and Metabolism …
Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … with aspartic acid. ... body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids ... Compared to human insulin, it has a single amino acid substitution at position B28 where proline is replaced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... insulin degludec and insulin aspart ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … .Insulin Aspart Protamine and Insulin Aspart ... Insulin Aspart Protamine and Insulin Aspart Mix 70/30 …
This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As...
Approved
Vet approved
Matched Description: … It is available in various preparations, including creams, pessaries, and troche formulations (slowly ... has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and ... The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain …
Matched Mixtures name: … CLOTRIMAZOL ACIS 3 KOMBI ... CLOTRIMAZOL ACIS 3 KOMBI ... Clotrimazole and Betamethasone Dipropionate …
Matched Categories: … Imidazole and Triazole Derivatives ... Antiinfectives and Antiseptics for Local Oral Treatment ... Gynecological Antiinfectives and Antiseptics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Kerasal foot and toe ... Protective Nail and skin ... Up and Up Athletes Foot …
Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Synonyms: … N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic ... acid ... L-Folinic acid
Matched Iupac: … -amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid
Matched Description: … This important pathway, which is required for de novo synthesis of nucleic acids and amino acids, is ... acid or leucovorin). ... and methionine before incorporation into DNA or protein. …
Matched Categories: … Folic Acid and Derivatives ... Enzymes and Coenzymes ... Folic Acid Analogues …
Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Synonyms: … N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid ... 4-amino-10-methylfolic acid ... 4-amino-N(10)-methylpteroylglutamic acid
Matched Iupac: … -[(4-{[(4-amino-2-imino-2,3-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid
Matched Description: … Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and ... inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists ... Nucleic Acid Synthesis Inhibitors …
A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Approved
Vet approved
Matched Synonyms: … (5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester …
Matched Iupac: … methyl N-(6-benzoyl-1H-1,3-benzodiazol-2-yl)carbamate …
Matched Description: … A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Acids, Acyclic ... Carboxylic Acids
Experimental
Matched Name: … 2,4-Difluorobenzyl Alcohol 2,4-Difluoro-1-(Hydroxymethyl)Benzene …
Investigational
Matched Synonyms: … Cinnamic acidum ... E-cinnamic acid ... 2-propenoic acid, 3-phenyl- …
Matched Name: … Cinnamic acid
Matched Iupac: … (2E)-3-phenylprop-2-enoic acid
Matched Categories: … Heparin and similars ... Acids, Carbocyclic ... Carboxylic Acids
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and...
Approved
Matched Synonyms: … (±)-p-isobutylhydratropic acid ... 4-isobutylhydratropic acid ... (±)-2-(p-isobutylphenyl)propionic acid
Matched Iupac: … 2-[4-(2-methylpropyl)phenyl]propanoic acid
Matched Description: … Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered ... [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development ... in the UK in 1969 and USA in 1974. …
Matched Mixtures name: … ALCADOL®GRIPA ... ALCADOL® ULTRA ... Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17% …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Arylpropionic acid NSAIDS ... Ibuprofen and isomer ... codeine and ibuprofen …
Matched Products: … ALCADOL® ... ALCADOL ® 400 MG ... ALCADOL® 100MG/5ML …
Experimental
Matched Name: … (2R)-2-benzyl-3-nitropropanoic acid
Matched Iupac: … (2R)-2-benzyl-3-nitropropanoic acid
Procysteine has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Synonyms: … (-)-2-OXO-4-THIAZOLIDINECARBOXYLIC ACID ... (R)-2-OXOTHIAZOLIDINE-4-CARBOXYLIC ACID ... 2-OXO-4-THIAZOLIDINECARBOXYLIC ACID, L- …
Matched Name: … Oxothiazolidinecarboxylic acid
Matched Iupac: … (4R)-2-oxo-1,3-thiazolidine-4-carboxylic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic …
Displaying drugs 451 - 475 of 2637 in total