Displaying drugs 451 - 475 of 2485 in total
Grazoprevir
Grazoprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Synonyms: … Grazoprevir anhydrous …
Matched Description: … Subtitutions at amino acid positions 155, 156, or 168 are known to confer resistance. ... with or without [DB00811] depending on the the presence of resistance associated amino acid substitutions ... to achieve a SVR between 94% and 97% for genotype 1 and 97% and 100% for genotype 4 after 12 weeks of …
Matched Categories: … elbasvir and grazoprevir ... Acids, Acyclic ... Carboxylic Acids …
Matched Description: … Subtitutions at amino acid positions 155, 156, or 168 are known to confer resistance. ... with or without [DB00811] depending on the the presence of resistance associated amino acid substitutions ... to achieve a SVR between 94% and 97% for genotype 1 and 97% and 100% for genotype 4 after 12 weeks of …
Matched Categories: … elbasvir and grazoprevir ... Acids, Acyclic ... Carboxylic Acids …
Navarixin
Navarixin has been investigated for the treatment of Asthma.
Investigational
Matched Synonyms: … Navarixin anhydrous …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Peramivir
Peramivir is an antiviral agent developed by Biocryst Pharmaceuticals to treat influenza A/B. The development of peramivir has been supported by the US Department of Health and Human Services as part of the government's effort to prepare for a flu pandemic. Being an influenza virus neuraminidase inhibitor, peramivir works by...
Approved
Investigational
Matched Synonyms: … Peramivir anhydrous …
Matched Iupac: … 1S,2S,3R,4R)-4-carbamimidamido-3-[(1S)-1-acetamido-2-ethylbutyl]-2-hydroxycyclopentane-1-carboxylic acid …
Matched Description: … The development of peramivir has been supported by the US Department of Health and Human Services as ... the poor oral bioavailability, the oral formulation of the drug was previously abandoned by Johnson and ... in September 2017 for the treatment of acute uncomplicated influenza to pediatric patients 2 years and …
Matched Categories: … Carboxylic Acids …
Matched Iupac: … 1S,2S,3R,4R)-4-carbamimidamido-3-[(1S)-1-acetamido-2-ethylbutyl]-2-hydroxycyclopentane-1-carboxylic acid …
Matched Description: … The development of peramivir has been supported by the US Department of Health and Human Services as ... the poor oral bioavailability, the oral formulation of the drug was previously abandoned by Johnson and ... in September 2017 for the treatment of acute uncomplicated influenza to pediatric patients 2 years and …
Matched Categories: … Carboxylic Acids …
Biotin
A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Approved
Investigational
Nutraceutical
Matched Synonyms: … (+)-cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric acid ... cis-Hexahydro-2-oxo-1H-thieno(3,4)imidazole-4-valeric acid ... 5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid …
Matched Iupac: … 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid …
Matched Description: … and milk. ... It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, …
Matched Mixtures name: … Pro Pcos Citrus ... Folivane-Plus with Ascorbic Acid Precursors ... B-complex With Vitamin C, Biotin, Folic Acid …
Matched Categories: … Enzymes and Coenzymes ... Diet, Food, and Nutrition ... Alimentary Tract and Metabolism …
Matched Products: … Biona-vit Controls and Prevents Hair Loss …
Matched Iupac: … 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid …
Matched Description: … and milk. ... It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, …
Matched Mixtures name: … Pro Pcos Citrus ... Folivane-Plus with Ascorbic Acid Precursors ... B-complex With Vitamin C, Biotin, Folic Acid …
Matched Categories: … Enzymes and Coenzymes ... Diet, Food, and Nutrition ... Alimentary Tract and Metabolism …
Matched Products: … Biona-vit Controls and Prevents Hair Loss …
Dabocemagene autoficel
Dabocemagene autoficel is an ex vivo, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.
Investigational
Matched Synonyms: … AUTOLOGOUS HUMAN DERMAL FIBROBLAST CELLS DERIVED FROM SKIN BIOPSIES, AND TRANSDUCED WITH A NON-REPLICATING ... INTEGRATED PROVIRAL HUMAN COLLAGEN TYPE VII TRANSGENE COL7A1 PLUS 5'-HUMAN CYTOMEGALOVIRUS PROMOTER/UTR-AND …
Oxidronic acid
Approved
Matched Synonyms: … Acido oxidronico ... Oxidronic acid ... Acidum oxidronicum …
Matched Name: … Oxidronic acid …
Matched Iupac: … [hydroxy(phosphono)methyl]phosphonic acid …
Matched Name: … Oxidronic acid …
Matched Iupac: … [hydroxy(phosphono)methyl]phosphonic acid …
Olopatadine
Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved
Matched Iupac: … dimethylamino)propylidene]-9-oxatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-5-yl]acetic acid …
Matched Description: … seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. ... inflammatory and allergic reactions. ... Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Eye Allergy Itch and Redness Relief ... Eye Allergy Itch and Redness Relief Twice Daily Relief …
Matched Description: … seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. ... inflammatory and allergic reactions. ... Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Eye Allergy Itch and Redness Relief ... Eye Allergy Itch and Redness Relief Twice Daily Relief …
Flufenamic acid
An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. (From Martindale, The Extra Pharmacopoeia, 30th ed, p16)
Approved
Matched Synonyms: … Flufenamic acid ... acide flufénamique ... Acidum flufenamicum …
Matched Name: … Flufenamic acid …
Matched Iupac: … 2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid …
Matched Description: … An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. ... It is used in musculoskeletal and joint disorders and administered by mouth and topically. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic ... Carboxylic Acids ... flufenamic acid …
Matched Name: … Flufenamic acid …
Matched Iupac: … 2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid …
Matched Description: … An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. ... It is used in musculoskeletal and joint disorders and administered by mouth and topically. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic ... Carboxylic Acids ... flufenamic acid …
Argatroban
Argatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary intervention. Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients...
Approved
Investigational
Matched Synonyms: … Argatroban anhydrous …
Matched Iupac: … carbamimidamido-2-(3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)pentanoyl]-4-methylpiperidine-2-carboxylic acid …
Matched Description: … Parental anticoagulants must be stopped and a baseline activated partial thromboplastin time must be ... bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and ... Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients with HIT and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Heterocyclic ... Amino Acids, Basic …
Matched Iupac: … carbamimidamido-2-(3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)pentanoyl]-4-methylpiperidine-2-carboxylic acid …
Matched Description: … Parental anticoagulants must be stopped and a baseline activated partial thromboplastin time must be ... bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and ... Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients with HIT and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Heterocyclic ... Amino Acids, Basic …
Regadenoson
Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Approved
Investigational
Matched Synonyms: … Regadenoson anhydrous …
Matched Description: … Manufactured by Astellas and FDA approved April 10, 2008. ... Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial …
Matched Description: … Manufactured by Astellas and FDA approved April 10, 2008. ... Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial …
Enalaprilat
Enalaprilat is the active metabolite of the orally available pro-drug, enalapril. Used in the treatment of hypertension, enalapril is an ACE inhibitor that prevents Angiotensin Converting Enzyme (ACE) from transforming angiotensin I into angiotensin II. As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule of...
Approved
Matched Synonyms: … Enalaprilat anhydrous …
Matched Iupac: … (2S)-1-[(2S)-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}propanoyl]pyrrolidine-2-carboxylic acid …
Matched Description: … As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule ... of the kidney, down-regulation of this protein results in reduced blood pressure and blood fluid volume ... to overcome the limitations of the first ACE inhibitor, captopril, which had numerous side effects and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … (2S)-1-[(2S)-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}propanoyl]pyrrolidine-2-carboxylic acid …
Matched Description: … As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule ... of the kidney, down-regulation of this protein results in reduced blood pressure and blood fluid volume ... to overcome the limitations of the first ACE inhibitor, captopril, which had numerous side effects and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tofogliflozin
Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type 2.
Investigational
Matched Synonyms: … Tofogliflozin anhydrous …
Matched Description: … Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type …
Matched Description: … Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type …
Relebactam
Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to avibactam.[A181195,A181207] It includes a piperidine ring which reduces export from bacterial cells by producing a positive charge. It is currently available in a combination product which includes imipenem and cilastatin to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated...
Approved
Investigational
Matched Synonyms: … Relebactam anhydrous …
Matched Iupac: … [(1R,2S,5R)-7-oxo-2-[(piperidin-4-yl)carbamoyl]-1,6-diazabicyclo[3.2.1]octan-6-yl]oxidanesulfonic acid …
Matched Description: … [A181207] It is currently available in a combination product which includes [imipenem] and [cilastatin ... ] to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated intra-abdominal ... [label] It is considered to be a last-line treatment option and gained FDA approval as part of the combination …
Matched Categories: … imipenem, cilastatin and relebactam …
Matched Iupac: … [(1R,2S,5R)-7-oxo-2-[(piperidin-4-yl)carbamoyl]-1,6-diazabicyclo[3.2.1]octan-6-yl]oxidanesulfonic acid …
Matched Description: … [A181207] It is currently available in a combination product which includes [imipenem] and [cilastatin ... ] to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated intra-abdominal ... [label] It is considered to be a last-line treatment option and gained FDA approval as part of the combination …
Matched Categories: … imipenem, cilastatin and relebactam …
Labetalol
Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730]
Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Categories: … Alpha and Beta Blocking Agents and Thiazides ... Alpha and Beta Blocking Agents ... labetalol and thiazides ... labetalol and other diuretics ... Beta Blocking Agents and Thiazides …
Matched Products: … BLOCAMINE (Labetalol hydrochloride 5 mg/ml solution for Injection and for Infusion) …
Matched Products: … BLOCAMINE (Labetalol hydrochloride 5 mg/ml solution for Injection and for Infusion) …
Calcium chloride
Calcium chloride is an ionic compound of calcium and chlorine. It is highly soluble in water and it is deliquescent. It is a salt that is solid at room temperature, and it behaves as a typical ionic halide. It has several common applications such as brine for refrigeration plants, ice...
Approved
Matched Synonyms: … Calcium chloride anhydrous ... Calcium chloride, anhydrous …
Matched Description: … , and in cement. ... It is highly soluble in water and it is deliquescent. ... Calcium chloride is an ionic compound of calcium and chlorine. …
Matched Mixtures name: … Magnesium Hydroxide ... CALCIO E MAGNESIO CLORURO FKI ... Ringers and Dextrose …
Matched Categories: … ascorbic acid (vit C) and calcium ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Genito Urinary System and Sex Hormones …
Matched Description: … , and in cement. ... It is highly soluble in water and it is deliquescent. ... Calcium chloride is an ionic compound of calcium and chlorine. …
Matched Mixtures name: … Magnesium Hydroxide ... CALCIO E MAGNESIO CLORURO FKI ... Ringers and Dextrose …
Matched Categories: … ascorbic acid (vit C) and calcium ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Genito Urinary System and Sex Hormones …
Orotic acid
Investigational
Matched Synonyms: … Orotic acid ... Acido orotico ... Acidum oroticum …
Matched Name: … Orotic acid …
Matched Iupac: … 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid …
Matched Categories: … Acids, Heterocyclic …
Matched Name: … Orotic acid …
Matched Iupac: … 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid …
Matched Categories: … Acids, Heterocyclic …
Mucor circinelloides f. lusitanicus
Mucor circinelloides f. lusitanicus allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. lusitanicus …
STRO-001
Investigational
Matched Synonyms: … antibody-drug conjugate comprised of a human aglycosylated anti-CD74 IgG1 antibody (SP7219) and two non-cleavable …
PRGN-3006
PRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface.
Investigational
Matched Synonyms: … genetically modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and …
Matched Description: … genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and …
Matched Description: … genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and …
Maltose
A dextrodisaccharide from malt and starch. It is used as a sweetening agent and fermentable intermediate in brewing (Grant & Hackh's Chemical Dictionary, 5th ed).
Experimental
Investigational
Matched Synonyms: … Maltose anhydrous …
Matched Description: … A dextrodisaccharide from malt and starch. ... It is used as a sweetening agent and fermentable intermediate in brewing (Grant & Hackh's Chemical …
Matched Categories: … Diet, Food, and Nutrition …
Matched Description: … A dextrodisaccharide from malt and starch. ... It is used as a sweetening agent and fermentable intermediate in brewing (Grant & Hackh's Chemical …
Matched Categories: … Diet, Food, and Nutrition …
Gadodiamide
Gadodiamide is a linear, non-ionic gadolinium-based contrast agent (GBCA) that is used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels.[A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than nonionic iodinated contrast agents. Approved by the FDA...
Approved
Investigational
Matched Synonyms: … Gadodiamide anhydrous …
Matched Description: … [A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than ... macrocyclic or ionic GBCA, gadodiamide can potentially lead to more gadolinium retention in the brain and …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Description: … [A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than ... macrocyclic or ionic GBCA, gadodiamide can potentially lead to more gadolinium retention in the brain and …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Ubidecarenone
Ubidecarenone, also called coenzyme Q10, is a 1,4-benzoquinone. From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation. The ubidecarenone is...
Approved
Investigational
Nutraceutical
Matched Description: … From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number ... [A7874] It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative ... [L1062] Ubidecarenone is sold as a dietary supplement and is not FDA approved as a drug - it is not meant …
Matched Mixtures name: … Vitamin E and Coq10 ... Co-q10 and Vitamin E ... Co-q10 M.R.B. 100mg and Vitamin E …
Matched Categories: … Enzymes and Coenzymes ... Diet, Food, and Nutrition …
Matched Products: … Coenzyme Q10 With Hawthorn Extract and Citrus Bioflavonoids …
Matched Mixtures name: … Vitamin E and Coq10 ... Co-q10 and Vitamin E ... Co-q10 M.R.B. 100mg and Vitamin E …
Matched Categories: … Enzymes and Coenzymes ... Diet, Food, and Nutrition …
Matched Products: … Coenzyme Q10 With Hawthorn Extract and Citrus Bioflavonoids …
Hydroxocobalamin
Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.
Approved
Matched Synonyms: … Hydroxocobalamin anhydrous ... Hydroxocobalaminum anhydrous …
Matched Description: … It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. ... Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B …
Matched Categories: … Vitamin B12 and Folic Acid ... Blood and Blood Forming Organs …
Matched Description: … It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. ... Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B …
Matched Categories: … Vitamin B12 and Folic Acid ... Blood and Blood Forming Organs …
Displaying drugs 451 - 475 of 2485 in total