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Displaying drugs 451 - 475 of 733 in total
Investigational
Matched Synonyms: … -d-glucopyranosyloxy)-22-hydroxyfurostan-3-yl o-.beta.-d-glucopyranosyl-(1->2)-o-(.beta. ... -d-xylopyranosyl-(1->3))-o-.beta.-d-glucopyranosyl-(1->4)- …
Matched Iupac: … }-4-{[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy}oxan-2-yl]oxy}-6-(hydroxymethyl)oxan-2-yl]oxy}-6-hydroxy ... 5R,6R)-5-hydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy
Experimental
Matched Synonyms: … 1-O-(4-nitrophenyl)-β-D-galactose ... 1-O-(p-nitrophenyl)-β-D-galactose ... 1-O-(4-nitrophenyl)-β-D-galactopyranose …
Matched Categories: … Indicators and Reagents ... Compounds used in a research, industrial, or household setting …
Experimental
Matched Synonyms: … Methyl 4,6-O-[(1R)-1-carboxyethylidene]-β-D-galactopyranoside …
Matched Name: … Methyl 4,6-O-[(1R)-1-carboxyethylidene]-beta-D-galactopyranoside …
Experimental
Matched Synonyms: … 2-acetamido-2-deoxy-6-O-phosphono-D-glucopyranose …
Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension.[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors[L8390,L8423] or angiotensin II receptor blockers.[L7426,L7459] Hydrochlorothiazide was granted FDA...
Approved
Vet approved
Matched Description: … [A185138] It is indicated to treat edema and hypertension. ... [A185138] Many combination products are available containing hydrochlorothiazide and angiotensin converting ... enzyme inhibitors[L8390,L8423] or angiotensin II receptor blockers. …
Matched Mixtures name: … Lisinopril and Hydrochlorothiazide ... Lisinopril and Hydrochlorothiazide ... Lisinopril and HCTZ …
Matched Categories: … combinations of sulfonamides ... Genito Urinary System and Sex Hormones ... hydrochlorothiazide and potassium ... aliskiren and hydrochlorothiazide ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Losartan Potassium and Hydrochlorothiazide …
Experimental
Matched Synonyms: … O,O-Diethyl phosphonate …
Vet approved
Matched Synonyms: … Methyl O-methyl-18-epireserpate …
Experimental
Matched Synonyms: … p-Cymen-2-ol ... 5-Isopropyl-o-cresol …
Investigational
Matched Synonyms: … 2,3-o-Desulfated heparin (12000 da) …
Matched Categories: … Heparin and similars …
A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Approved
Matched Synonyms: … 2-(Propylamino)-o-propionotoluidide ... o-Methyl-2-propylaminopropionanilide ... o-Methyl-alpha-propylaminopropionanilide …
Matched Mixtures name: … Lidocaine and Prilocaine ... Lidocaine and Prilocaine ... Lidocaine and Prilocaine …
Investigational
Matched Synonyms: … (L120>A,L121>E,G123>A,A216>S,P217>S)-TACI (TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR, TUMOR NECROSIS …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Description: … UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. ... coagulation enzymes thrombin (factor IIa) and factor Xa. ... It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates …
Matched Mixtures name: … Heparin Sodium and Dextrose 5% Inj USP ... Heparin Sod and 0.9% Sod Chloride Inj …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs ... Heparins or Heparinoids for Topical Use …
Matched Products: … Heparin Sodium and Dextrose ... Heparin Sodium and Sodium Chloride …
Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. In August 2017, a combination antibacterial therapy under the market name vabomere...
Approved
Investigational
Matched Synonyms: … 4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo
Matched Iupac: … 5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo
Matched Description: … Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. ... It is active against Gram-positive and Gram-negative bacteria. ... Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis …
Matched Categories: … meropenem and vaborbactam …
Matched Products: … Meropenem and Sodium Chloride ... Meropenem for Injection USP and Sodium Chloride Injection USP ... Merozan 500mg powder for solution for injection or infusion …
Experimental
Matched Synonyms: … 2'-Deoxy-5'-O-[(R)-hydroxy(phosphonoamino)phosphoryl]uridine …
Investigational
Matched Synonyms: … 1-o-octadecyl-2-arachidonoyl-sn-glycerol-3-phosphoethanolamine …
Experimental
Matched Synonyms: … 2-(Butylamino)-6'-chloro-o-acetoluidide ... 2-Butylamino-6'-chloro-o-acetotoluidide …
Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with phentermine for chronic weight management therapy...
Approved
Matched Synonyms: … 2,3:4,5-di-O-isopropylidene-β-D-fructopyranose sulfamate ... 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate …
Matched Description: … Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. ... topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and ... 40% of its mass accounted for by oxygen. …
Matched Categories: … Alimentary Tract and Metabolism ... phentermine and topiramate …
Experimental
Matched Synonyms: … 4-O-β-D-mannopyranosyl-β-D-mannopyranose …
Matched Iupac: … (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-{[(2R,3S,4R,5S,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy
Experimental
Matched Synonyms: … 6-O-phosphono-β-D-galactopyranose …
Experimental
Matched Synonyms: … 1,4:3,6-Dianhydro-2,5-bis-O-(3-carbamimidoylphenyl)-D-glucitol …
Matched Name: … 2,5-bis-O-{3-[amino(imino)methyl]phenyl}-1,4:3,6-dianhydro-D-glucitol …
Matched Iupac: … 3-{[(3R,3aR,6S,6aR)-6-(3-carbamimidoylphenoxy)-hexahydrofuro[3,2-b]furan-3-yl]oxy}benzene-1-carboximidamide …
The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus...
Experimental
Matched Synonyms: … 2'-C-methylcytidine 3'-O-L-valinyl ester …
Matched Iupac: … (2R,3R,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)-4-methyloxolan- …
Matched Description: … This blocks viral production of HCV RNA and thus viral replication. [from NCI] ... upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and ... The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Epigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy.
Investigational
Matched Synonyms: … (-)-EPIGALLOCATECHIN-3-O-GALLATE ... EPIGALLOCATECHIN 3-O-GALLATE ... 3-O-GALLOYL-(-)-EPIGALLOCATECHIN …
Matched Description: … Epigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Investigational
Matched International brands: … Omnatax-O
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido]-3-ethenyl-8-oxo-5-thia …
Matched Description: … essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ultimately bacterial ... [A262995] Examples of third-generation cephalosporins are [ceftriaxone], [cefotaxime], and [ceftazidime ... , and meningitis. …
Matched Categories: … cefixime and ornidazole ... cefixime and azithromycin …
Matched Products: … FIXACEP OD ... TAXOCEF-O-200MG TABLET ... TAXOCEF-O-400MG TABLET …
Approved
Vet approved
Matched Synonyms: … 21-O-acetylcortisol …
Matched Iupac: … 2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H …
Matched Mixtures name: … Proctosone Ont ... Ophthocort Ont ... Sopamycetin/hc Ont
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … American Safety and First Aid ... Rectocort Ont ... Cortamed Ont 25 mg/g …
Uridine triacetate, formerly known as vistonuridine, is an orally active prodrug of the naturally occurring nucleoside uridine. It is used for the treatment of hereditary orotic aciduria (Xuriden), or for the emergency treatment of fluorouracil or capecitabine overdose or toxicity (Vistogard). It is provided in the prodrug form as uridine...
Approved
Investigational
Matched Synonyms: … Tri-O-acetyluridine ... 2',3',5'-tri-O-acetyluridine …
Matched Description: … When used for the treatment or prevention of toxicity associated with fluorouracil and other antimetabolites ... Normally, FdUMP inhibits thymidylate synthase required for thymidine synthesis and DNA replication and ... -5'-monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP). …
Matched Categories: … Alimentary Tract and Metabolism ... Nucleic Acids, Nucleotides, and Nucleosides ... Various Alimentary Tract and Metabolism Products …
Displaying drugs 451 - 475 of 733 in total