Did you mean interferon alpha 2b and interferon alpha 2b?
Displaying drugs 26 - 50 of 56 in total
L-Glutamine
A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. It is the principal carrier of nitrogen in the body and is an important energy source for many cells. An oral formulation of L-glutamine was approved...
Approved
Investigational
Nutraceutical
Matched Synonyms: … L-2-aminoglutaramic acid ... (2S)-2-amino-4-carbamoylbutanoic acid …
Matched Iupac: … (2S)-2-amino-4-carbamoylbutanoic acid …
Matched Description: … It is synthesized from glutamic acid and ammonia. ... A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes ... It is the principal carrier of nitrogen in the body and is an important energy source for many cells. …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Iupac: … (2S)-2-amino-4-carbamoylbutanoic acid …
Matched Description: … It is synthesized from glutamic acid and ammonia. ... A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes ... It is the principal carrier of nitrogen in the body and is an important energy source for many cells. …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Lenalidomide
Lenalidomide (previously referred to as CC-5013) is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. It is a 4-amino-glutamyl analogue of thalidomide and like thalidomide, lenalidomide exists as a racemic mixture of the active S(-) and R(+) forms. However, lenalidomide is much safer and potent than thalidomide, with...
Approved
Matched Synonyms: … 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline ... 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione …
Matched Iupac: … 3-(4-amino-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione …
Matched Description: … and toxicities. ... exists as a racemic mixture of the active S(-) and R(+) forms. ... [A228708] However, lenalidomide is much safer and potent than thalidomide, with fewer adverse effects …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 3-(4-amino-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione …
Matched Description: … and toxicities. ... exists as a racemic mixture of the active S(-) and R(+) forms. ... [A228708] However, lenalidomide is much safer and potent than thalidomide, with fewer adverse effects …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antineoplastic and Immunomodulating Agents …
Paritaprevir
Paritaprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Synonyms: … (2R,6S,12Z,13aR,14aR,16aS)-N-(cyclopropanesulfonyl)-6-[(5-methylpyrazine-2-carbonyl)amino]-5,16-dioxo ... -2-[(phenanthridin-6-yl)oxy]-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydrocyclopropa[e]pyrrolo[ …
Matched Iupac: … (1S,4R,6S,7Z,14S,18R)-N-(cyclopropanesulfonyl)-14-(5-methylpyrazine-2-amido)-2,15-dioxo-18-(phenanthridin …
Matched Description: … interferon-based regimens, which were limited by infusion site reactions, reduced blood count, and neuropsychiatric ... : Viekira Pak (FDA), Technivie (FDA and Health Canada), and Holkira Pak (Health Canada). ... FDA- and Health Canada-approved product Technivie. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ombitasvir, paritaprevir and ritonavir ... dasabuvir, ombitasvir, paritaprevir and ritonavir …
Matched Iupac: … (1S,4R,6S,7Z,14S,18R)-N-(cyclopropanesulfonyl)-14-(5-methylpyrazine-2-amido)-2,15-dioxo-18-(phenanthridin …
Matched Description: … interferon-based regimens, which were limited by infusion site reactions, reduced blood count, and neuropsychiatric ... : Viekira Pak (FDA), Technivie (FDA and Health Canada), and Holkira Pak (Health Canada). ... FDA- and Health Canada-approved product Technivie. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ombitasvir, paritaprevir and ritonavir ... dasabuvir, ombitasvir, paritaprevir and ritonavir …
Myrrh
Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, obtained from Commiphora abyssinica, Burseraceae.
Approved
Matched Description: … Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential …
Ribavirin
Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. It is primarily indicated for use in treating hepatitis C and viral hemorrhagic fevers. HCV is a single-stranded RNA virus that is categorized...
Approved
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide …
Matched Description: … in patients with genotype 2 and 3 [A19626]. ... infection and 70% in patients with genotype 2-6. ... In HCV genotye 1/2/3/4/5/6 patients, ribavirin can be used in combination therapy involving [DB09102] …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … Nucleosides and Nucleotides ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … in patients with genotype 2 and 3 [A19626]. ... infection and 70% in patients with genotype 2-6. ... In HCV genotye 1/2/3/4/5/6 patients, ribavirin can be used in combination therapy involving [DB09102] …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … Nucleosides and Nucleotides ... Nucleic Acids, Nucleotides, and Nucleosides …
Bleomycin
A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.
Approved
Investigational
Matched Iupac: … (3-{[2-(2-{2-[(2S,3R)-2-[(2S,3S,4R)-4-[(2S,3R)-2-({6-amino-2-[(1S)-1-{[(2S)-2-amino-2-carbamoylethyl] ... hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy]-3-(1H-imidazol-4-yl)propanamido ... amino}-2-carbamoylethyl]-5-methylpyrimidin-4-yl}formamido)-3-[(3-{[4-(carbamoyloxy)-3,5-dihydroxy-6-( ... ]-3-hydroxy-2-methylpentanamido]-3-hydroxybutanamido]ethyl}-1,3-thiazol-4-yl)-1,3-thiazol-4-yl]formamido …
Matched Description: … It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. ... of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Description: … It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. ... of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Lisocabtagene maraleucel
Lisocabtagene maraleucel is a chimeric antigen receptor (CAR) T-cell therapy, similar to brexucabtagene autoleucel and axicabtagene ciloleucel.[A228493,L31588] Lisocabtagene maraleucel is a genetically modified autologous T-cell therapy that targets CD19, the B-lymphocyte surface antigen B4. CAR T-cell therapy has changed the treatment of B-cell lymphomas, significantly increasing survival rates over standard...
Approved
Matched Description: … maraleucel is a chimeric antigen receptor (CAR) T-cell therapy, similar to [brexucabtagene autoleucel] and ... [A228493]
Lisocabtagene maraleucel was granted FDA approval on 5 February 2021 [L31583] and EC approval ... [L31588]
CAR T-cell therapy has changed the treatment of B-cell lymphomas, significantly increasing …
Matched Categories: … Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Aldesleukin
Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from...
Approved
Matched Synonyms: … Interleukin-2(2-133),125-ser ... 125-L-serine-2-133-interleukin 2 (human reduced) ... Interleukin-2 aldesleukin …
Matched Description: … Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression ... glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon ... clone encodes a modified human interleukin-2. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression ... glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon ... clone encodes a modified human interleukin-2. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Ocrelizumab
Ocrelizumab is a CD20-directed cytolytic antibody indicated for the treatment of patients with primary progressive or relapsing forms of multiple sclerosis (MS). It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively targets B-cells that express the CD20 antigen. Compared to non-humanized CD20 antibodies such as rituximab, ocrelizumab is...
Approved
Investigational
Matched Description: … reduced worsening of disability compared to [interferon beta-1a]. ... ] It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively targets B-cells ... inflammatory, autoimmune disease of the central nervous system that leads to neurological disabilities and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … OCREVUS 300 MG/10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 2 ADET …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … OCREVUS 300 MG/10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 2 ADET …
Boceprevir
Boceprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Withdrawn
Matched Iupac: … [3.1.0]hexan-2-yl]formamido}-4-cyclobutyl-2-oxobutanamide ... 3-{[(1R,2S,5S)-3-[(2S)-2-[(tert-butylcarbamoyl)amino]-3,3-dimethylbutanoyl]-6,6-dimethyl-3-azabicyclo …
Matched Description: … Victrelis is no longer widely used as interferon-free therapies have been developed. ... into mature proteins like NS4A, NS4B, NS5A and NS5B [FDA Label]. ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Victrelis is no longer widely used as interferon-free therapies have been developed. ... into mature proteins like NS4A, NS4B, NS5A and NS5B [FDA Label]. ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Daclatasvir
Daclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection. It is marketed under the name DAKLINZA and is contained in daily oral tablets as the hydrochloride salt form . Hepatitis C is an infectious liver disease...
Approved
Investigational
Matched Iupac: … methyl N-[(2S)-1-[(2S)-2-[5-(4'-{2-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl]pyrrolidin ... 2-yl]carbamate ... -2-yl]-1H-imidazol-5-yl}-[1,1'-biphenyl]-4-yl)-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan- …
Matched Description: … 3 without the need for co-administration of interferon or [DB00811]. ... of Liver Diseases (AASLD), 60mg of daclatasvir is recommended with 400mg [DB08934] for genotype 1a/b ... daclatasvir and [DB08934] therapy were 88% and 99%, respectively [FDA Label]. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... daclatasvir, asunaprevir and beclabuvir …
Matched Description: … 3 without the need for co-administration of interferon or [DB00811]. ... of Liver Diseases (AASLD), 60mg of daclatasvir is recommended with 400mg [DB08934] for genotype 1a/b ... daclatasvir and [DB08934] therapy were 88% and 99%, respectively [FDA Label]. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... daclatasvir, asunaprevir and beclabuvir …
Cepeginterferon alfa-2B
Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C).
Investigational
Matched Synonyms: … Cepeginterferon Alfa 2 B ... Pegylated human interferon A-2B ... Cepeginterferon alfa-2B …
Matched Name: … Cepeginterferon alfa-2B …
Matched Description: … Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic ... Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative …
Matched Categories: … cepeginterferon alfa-2b ... Antineoplastic and Immunomodulating Agents …
Matched Name: … Cepeginterferon alfa-2B …
Matched Description: … Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic ... Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative …
Matched Categories: … cepeginterferon alfa-2b ... Antineoplastic and Immunomodulating Agents …
Albinterferon Alfa-2B
Albumin-interferon alpha (Albuferon) is a novel, long-acting form of interferon alpha. Recombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range of cancers. Human Genome Sciences modified interferon alpha to improve its pharmacological properties by using the company's proprietary albumin fusion technology. Human...
Investigational
Matched Synonyms: … Albinterferon Alfa-2B ... Albumin-interferon alpha …
Matched Name: … Albinterferon Alfa-2B …
Matched Description: … Recombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range ... Albumin-interferon alpha (Albuferon) is a novel, long-acting form of interferon alpha. ... In response to an FDA ruling, Novartis and Human Genome Sciences announced on October 5, 2010 that they …
Matched Categories: … albinterferon alfa-2b ... Interferon Type I ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Name: … Albinterferon Alfa-2B …
Matched Description: … Recombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range ... Albumin-interferon alpha (Albuferon) is a novel, long-acting form of interferon alpha. ... In response to an FDA ruling, Novartis and Human Genome Sciences announced on October 5, 2010 that they …
Matched Categories: … albinterferon alfa-2b ... Interferon Type I ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Interferon alfa
Natural interferon alpha or Multiferon is obtained from the leukocyte fraction of human blood following induction with Sendai virus. Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography. Interferon alpha proteins are mainly involved in innate immune response against viral infection. They come in 13...
Investigational
Matched Synonyms: … Interferon alfa ... Natural alpha interferon …
Matched Name: … Interferon alfa …
Matched Description: … Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography ... Of these, IFN-α2 and IFN-α14 are glycosylated. ... Natural interferon alpha or Multiferon is obtained from the leukocyte fraction of human blood following …
Matched Categories: … Interferon-alpha ... Interferon Type I ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Name: … Interferon alfa …
Matched Description: … Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography ... Of these, IFN-α2 and IFN-α14 are glycosylated. ... Natural interferon alpha or Multiferon is obtained from the leukocyte fraction of human blood following …
Matched Categories: … Interferon-alpha ... Interferon Type I ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Interferon alfa-1b
Investigational
Matched Synonyms: … INTERFERON-ALFA-1B ... INTERFERON ALPHA 1B ... Interferon alpha-1b …
Matched Name: … Interferon alfa-1b …
Matched Categories: … Interferon Type I ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Name: … Interferon alfa-1b …
Matched Categories: … Interferon Type I ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Interferon alfa-2c
Interferon alfa-2c is under investigation in clinical trial NCT00485563 (A Phase II Study of EC17 (Folate-hapten Conjugate) in Patients With Progressive Metastatic Renal Cell Carcinoma).
Investigational
Matched Name: … Interferon alfa-2c …
Matched Description: … Interferon alfa-2c is under investigation in clinical trial NCT00485563 (A Phase II Study of EC17 (Folate-hapten …
Matched Categories: … Interferon Type I ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Interferon alfa-2c is under investigation in clinical trial NCT00485563 (A Phase II Study of EC17 (Folate-hapten …
Matched Categories: … Interferon Type I ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Peginterferon alfacon-1
PEGylation is a technology for the chemical attachment of polyethylene glycol (PEG) polymer chains to a broad range of drug substances such as peptides and proteins including antibody fragments; small molecules, and other drugs. [Infergen] is a bio-engineered type I interferon alpha that is FDA-approved for the treatment of patients...
Investigational
Matched Synonyms: … PEG-interferon alfacon-1 ... Pegylated interferon alfacon-1 …
Matched Description: … [Infergen] is a bio-engineered type I interferon alpha that is FDA-approved for the treatment of patients ... proteins including antibody fragments; small molecules, and other drugs. ... attachment of polyethylene glycol (PEG) polymer chains to a broad range of drug substances such as peptides and …
Matched Description: … [Infergen] is a bio-engineered type I interferon alpha that is FDA-approved for the treatment of patients ... proteins including antibody fragments; small molecules, and other drugs. ... attachment of polyethylene glycol (PEG) polymer chains to a broad range of drug substances such as peptides and …
EI-001
Investigational
Matched Synonyms: … Human monoclonal antibody based on an IgG1 lambda framework against human interferon gamma …
QXL138AM
QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a. It binds the CD138 protein on the surface of the tumour cells.
Investigational
Matched Synonyms: … Masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon …
Matched Description: … QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon …
Matched Description: … QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon …
Dazukibart
Investigational
Matched Synonyms: … Immunoglobulin G1 [236-alanine,237-alanine,239-alanine,de-C-terminal-lysine], anti-(human interferon ... (immunoglobulin gamma-1 with kappa light chains, IgG1kappa) directed against human soluble cytokine interferon …
BLX-883
BLX-883 is a form of alfa interferon developed by Biolex for the treatment of hepatitis viral C. Alfa interferon is used in the treatment of hepatitis C, hepatitis B, and multiple cancers and its worldwide sales currently exceed $3 billion.
Investigational
Matched Description: … Alfa interferon is used in the treatment of hepatitis C, hepatitis B, and multiple cancers and its worldwide ... BLX-883 is a form of alfa interferon developed by Biolex for the treatment of hepatitis viral C. …
Tilorone
Investigational
Matched Iupac: … 2,7-bis[2-(diethylamino)ethoxy]-9H-fluoren-9-one …
Matched Categories: … Interferon Inducers …
Matched Categories: … Interferon Inducers …
Bropirimine
Experimental
Matched Iupac: … 2-amino-5-bromo-6-phenyl-1,4-dihydropyrimidin-4-one …
Matched Categories: … Interferon Inducers …
Matched Categories: … Interferon Inducers …
OM85
OM-85, a bacterial extract, is an immunomodulator of interferon-β production and inflammasome activity.
Investigational
Matched Description: … OM-85, a bacterial extract, is an immunomodulator of interferon-β production and inflammasome activity …
Propagermanium
Investigational
Matched Synonyms: … Bis (2-carboxyethylgermanium)sesquioxide ... 3-[[2-carboxyethyl(oxo)germyl]oxy-oxogermyl]propanoic acid …
Matched Iupac: … bis((2-carboxyethyl)germanetris(ylium)) trioxidandiide …
Matched Categories: … Interferon Inducers …
Matched Iupac: … bis((2-carboxyethyl)germanetris(ylium)) trioxidandiide …
Matched Categories: … Interferon Inducers …
Displaying drugs 26 - 50 of 56 in total