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Displaying drugs 26 - 50 of 14930 in total
Lauric acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression. Lauric acid is a solid at room temperature but melts easily in boiling water, so liquid lauric acid can be treated with various solutes and used to determine their molecular masses.
Approved
Experimental
Matched Synonyms: … C12 fatty acid ... Dodecoic acid ... Vulvic acid
Matched Name: … Lauric acid
Matched Iupac: … dodecanoic acid
Matched Description: … Lauric acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations ... Lauric acid is a solid at room temperature but melts easily in boiling water, so liquid lauric acid can ... be treated with various solutes and used to determine their molecular masses. …
Phenylbutyric acid is a fatty acid and a derivative of butyric acid naturally produced by colonic bacteria fermentation. It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting as a chemical chaperone. It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders.[L386,L42105]
Approved
Investigational
Matched Synonyms: … Benzenebutyric acid ... 4-phenylbutyric acid ... 4-Phenyl-n-butyric acid
Matched Name: … Phenylbutyric acid
Matched Iupac: … 4-phenylbutanoic acid
Matched Description: … Phenylbutyric acid is a fatty acid and a derivative of [butyric acid] naturally produced by colonic bacteria ... It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting ... [A249035] It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders. …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. In 2016, it was granted approval...
Approved
Matched Synonyms: … Obeticholic acid ... 6-ethylchenodeoxycholic acid ... 6α-ethylchenodeoxycholic acid
Matched Name: … Obeticholic acid
Matched Iupac: … 11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid
Matched Description: … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected ... Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... in patients with PBC and advanced cirrhosis (e.g. those with portal hypertension or hepatic decompensation …
Matched Categories: … Bile Acid Preparations ... obeticholic acid ... Bile Acids and Salts ... Bile and Liver Therapy ... Bile acids and derivatives …
Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Synonyms: … Alendronic acid ... 4-amino-1-hydroxybutane-1,1-diphosphonic acid ... (4-amino-1-hydroxybutylidene)bisphosphonic acid
Matched Name: … Alendronic acid
Matched Iupac: … (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid
Matched Description: … osteoperosis and Paget's disease[FDA Label][A959,A203111]. ... Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of …
Matched Categories: … alendronic acid and colecalciferol ... alendronic acid and alfacalcidol, sequential ... alendronic acid, calcium and colecalciferol, sequential ... alendronic acid ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … ALDRONA 70 (Alendronic acid Tablets 70 mg) …
An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Approved
Investigational
Nutraceutical
Matched Synonyms: … 2-ketopropionic acid ... 2-oxopropanoic acid ... Acetylformic acid
Matched Name: … Pyruvic acid
Matched Iupac: … 2-oxopropanoic acid
Matched Description: … An intermediate compound in the metabolism of carbohydrates, proteins, and fats. ... In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous …
Iopanoic acid contains iodine and is useful as a contrast medium in cholecystography.
Approved
Withdrawn
Matched Synonyms: … Iopanoic acid ... Iodopanoic acid
Matched Name: … Iopanoic acid
Matched Iupac: … 2-[(3-amino-2,4,6-triiodophenyl)methyl]butanoic acid
Matched Description: … Iopanoic acid contains iodine and is useful as a contrast medium in cholecystography. …
Matched Categories: … iopanoic acid
A compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. It is used as a photochemotherapy for actinic keratosis. [PubChem]
Approved
Matched Synonyms: … 5-Aminolevulinic acid ... Aminolevulinic acid ... δ-aminolevulinic acid
Matched Name: … Aminolevulinic acid
Matched Iupac: … 5-amino-4-oxopentanoic acid
Matched Description: … A compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. …
Matched Salts name: … Aminolevulinic acid hydrochloride …
Matched Categories: … aminolevulinic acid ... Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
Approved
Matched Synonyms: … Oxidronic acid ... Hydroxymethanediphosphonic acid ... (Hydroxymethylene)diphosphonic acid
Matched Name: … Oxidronic acid
Matched Iupac: … [hydroxy(phosphono)methyl]phosphonic acid
A member of the vitamin B complex. It used to be common in sunscreening agents until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.
Approved
Experimental
Matched Synonyms: … Aminobenzoic acid ... 4-aminobenzoic acid ... p-Aminobenzoic acid
Matched Name: … Aminobenzoic acid
Matched Iupac: … 4-aminobenzoic acid
Matched Categories: … Emollients and Protectives ... 4-Aminobenzoic Acid ... aminobenzoic acid
A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. [PubChem] Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug Administration as a treatment for children and adults with bile acid...
Approved
Matched Synonyms: … Cholic Acid
Matched Name: … Cholic Acid
Matched Iupac: … 11S,11aR)-4,7,11-trihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid
Matched Description: … A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. ... [PubChem] Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug ... Administration as a treatment for children and adults with bile acid synthesis disorders due to single …
Matched Categories: … cholic acid ... Bile Acid Preparations ... Bile Acids and Salts ... Bile and Liver Therapy ... Bile acids and derivatives …
The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Approved
Investigational
Matched Synonyms: … Aminohippuric acid ... 4-aminohippuric acid ... p-aminohippuric acid
Matched Name: … Aminohippuric acid
Matched Iupac: … 2-[(4-aminophenyl)formamido]acetic acid
Matched Description: … The glycine amide of 4-aminobenzoic acid. ... Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory …
Matched Categories: … aminohippuric acid ... Indicators and Reagents ... Benzamides and benzamide derivatives ... Tests for Renal Function and Ureteral Injuries …
The most common inhibitory neurotransmitter in the central nervous system.
Approved
Investigational
Matched Synonyms: … piperidic acid ... piperidinic acid ... 4-aminobutanoic acid
Matched Name: … gamma-Aminobutyric acid
Matched Iupac: … 4-aminobutanoic acid
Matched Salts name: … Gamma-Aminobutyric Acid Hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Gongjinhyang Qi and Jin Eye …
A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.
Approved
Matched Synonyms: … Cromoglicic acid ... Cromoglycic acid ... 5-[3-(2-carboxy-4-oxo-4H-5-chromenyloxy)-2-hydroxypropoxy]-4-oxo-4H-2-chromenecarboxylic acid
Matched Name: … Cromoglicic acid
Matched Iupac: … 5-{3-[(2-carboxy-4-oxo-4H-chromen-5-yl)oxy]-2-hydroxypropoxy}-4-oxo-4H-chromene-2-carboxylic acid
Matched Description: … It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect …
Matched Categories: … Alimentary Tract and Metabolism ... Decongestants and Antiallergics ... reproterol and sodium cromoglicate ... salbutamol and sodium cromoglicate ... cromoglicic acid
Nitrous acid (as sodium nitrite) is used as part of an intravenous mixture with sodium thiosulfate to treat cyanide poisoning. It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system. There is also research to investigate...
Approved
Investigational
Matched Synonyms: … dioxonitric acid
Matched Name: … Nitrous acid
Matched Iupac: … nitrous acid
Matched Description: … Nitrous acid (as sodium nitrite) is used as part of an intravenous mixture with sodium thiosulfate to ... applicability towards treatments for heart attacks, brain aneurysms, pulmonary hypertension in infants, and
Matched Categories: … Indicators and Reagents ... Diet, Food, and Nutrition …
Tiludronate, or (4-chlorophenyl)thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to etidronic acid and clodronic acid.[A1923,A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of bone....
Approved
Investigational
Vet approved
Matched Synonyms: … Tiludronic acid
Matched Name: … Tiludronic acid
Matched Iupac: … {[(4-chlorophenyl)sulfanyl](phosphono)methyl}phosphonic acid
Matched Description: … ] and [clodronic acid]. ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and ... [A202235] Tiludronic acid was granted FDA approval on 7 March 1997.[L4763] …
Matched Categories: … tiludronic acid ... Drugs Affecting Bone Structure and Mineralization …
Gadoxetic acid (gadoxetate) is a paramagnetic gadolinium-containing ionic linear contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection. Ethoxybenzyl diethylenetriaminepentaacetic acid is the moiety that chelates with a gadolinium ion and forms a stable complex with it to make up the drug. Gadoxetate is a...
Approved
Matched Synonyms: … Gadoxetic acid
Matched Name: … Gadoxetic acid
Matched Description: … Ethoxybenzyl diethylenetriaminepentaacetic acid is the moiety that chelates with a gadolinium ion and ... Gadoxetic acid (gadoxetate) is a paramagnetic gadolinium-containing ionic linear contrast agent in which ... [A263146] Gadoxetic acid, under the form gadoxetate disodium, is marketed by Bayer HealthCare Pharmaceuticals …
Matched Categories: … gadoxetic acid
Ioxitalamate is an ionic iodinated contrast medium. It is a first-generation contrast media formed by an ionic monomer with a high osmolarity of 1500-1800 mOsm/kg. Ioxitalamic acid in the salt forms of sodium and meglumine was developed by Liebel-Flarshem Canada Inc and approved by Health Canada in 1995. Until the...
Approved
Matched Synonyms: … Ioxitalamic acid
Matched Name: … Ioxitalamic acid
Matched Iupac: … 3-acetamido-5-[(2-hydroxyethyl)carbamoyl]-2,4,6-triiodobenzoic acid
Matched Description: … [A33006] Ioxitalamic acid in the salt forms of sodium and meglumine was developed by Liebel-Flarshem ... Canada Inc and approved by Health Canada in 1995. …
Matched Categories: … ioxitalamic acid
Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition.
Approved
Investigational
Nutraceutical
Matched Synonyms: … Linolenic acid ... α-linolenic acid ... (9,12,15)-linolenic acid
Matched Name: … alpha-Linolenic acid
Matched Iupac: … (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid
Matched Description: … Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. ... It is a component of many common vegetable oils and is important to human nutrition. …
Diaminohydroxypropanetetraacetic acid has been investigated for the treatment of Vascular Disease, Coronary Disease, Myocardial Ischemia, Coronary Restenosis, and Coronary Artery Disease, among others.
Approved
Investigational
Matched Synonyms: … Diaminohydroxypropanetetraacetic acid
Matched Name: … Diaminopropanol tetraacetic acid
Matched Iupac: … 2-({3-[bis(carboxymethyl)amino]-2-hydroxypropyl}(carboxymethyl)amino)acetic acid
Matched Description: … Disease, Myocardial Ischemia, Coronary Restenosis, and Coronary Artery Disease, among others. ... Diaminohydroxypropanetetraacetic acid has been investigated for the treatment of Vascular Disease, Coronary …
Omega-3-acid ethyl esters are prescription drugs that contain eicosapentaenoic acid-ethyl ester (EPA) and docosahexaenoic acid-ethyl ester (DHA) that are used in combination with changes in diet to lower triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia[FDA Label] . Omega-3-acid ethyl esters are currently marketed in the US, EU,...
Approved
Investigational
Matched Synonyms: … Omega-3-acid ethyl esters ... Omega-3 fatty acid ethyl esters …
Matched Name: … Omega-3-acid ethyl esters …
Matched Description: … and docosahexaenoic acid-ethyl ester (DHA) that are used in combination with changes in diet to lower ... Omega-3-acid ethyl esters are currently marketed in the US, EU, and many other regions under the brand ... Omega-3-acid ethyl esters are prescription drugs that contain eicosapentaenoic acid-ethyl ester (EPA) …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … Omega-3-acid Ethyl Esters ... Omega-3-Acid Ethyl Esters ... Omega-3-Acid Ethyl Ester …
Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used to prevent invasive meningococcal disease, which is caused by bacteria Neisseria meningitidis entering the bloodstream and invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and pneumonia. Several serogroups of N....
Approved
Matched Name: … Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine …
Matched Description: … Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used ... meningococcal disease, which is caused by bacteria _Neisseria meningitidis_ entering the bloodstream and ... invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and
Approved
Experimental
Matched Synonyms: … Testosterone enanthate benzilic acid hydrazone ... Testosterone 17-enanthate 3-benzilic acid hydrazone …
Matched Name: … Testosterone enantate benzilic acid hydrazone …
Matched Categories: … Testosterone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Synonyms: … N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid ... 4-amino-10-methylfolic acid ... 4-amino-N(10)-methylpteroylglutamic acid
Matched Iupac: … -[(4-{[(4-amino-2-imino-2,3-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid
Matched Description: … Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and ... inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists ... Nucleic Acid Synthesis Inhibitors …
Vayarin is a prescription medical food for the clinical dietary management of certain lipid imbalances blamed to be associated with attention deficit hyperactivity disorder (ADHD) in children. Vayarin contains Lipirinen, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and docosahexaenoic acid (DHA) [L1500, L1510]. Vayarin is currently available only...
Approved
Investigational
Matched Synonyms: … Phosphatidylserine, DHA, and EPA …
Matched Description: … ), and docosahexaenoic acid (DHA) [L1500, L1510]. ... _Lipirinen_, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid ... Cost of the drug and patient aversion to the taste of Vayarin were significant reasons for therapy failure …
Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Synonyms: … N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic ... acid ... L-Folinic acid
Matched Iupac: … -amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid
Matched Description: … acid or leucovorin). ... Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic ... acid antagonists, such as methotrexate, which act by inhibiting the enzyme dihydrofolate reductase ( …
Matched Categories: … Folic Acid and Derivatives ... Folic Acid Analogues ... Enzymes and Coenzymes …
Displaying drugs 26 - 50 of 14930 in total