Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 26 - 50 of 9336 in total

Magnesium Aluminum Silicate

Magnesium aluminum silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite group . It is refined to a powder for use in cosmetic and pharmaceutical applications as an absorbent, anticaking agent, opacifying agent, viscosity-increasing agent, suspending agent, tablet and capsule disintegrant, and tablet binder. It also...
Approved
Matched Description: … aluminum silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite group ... It is refined to a powder for use in cosmetic and pharmaceutical applications as an absorbent, anticaking ... agent, opacifying agent, viscosity-increasing agent, suspending agent, tablet and capsule disintegrant …

Potassium alum

Potassium alum is considered by the FDA as a generally recognized as safe (GRAS) substance. It is an inorganic salt, also called potassium aluminum sulfate with a formula of AlK(SO4)2 that is predominantly produced in the dodecahydrate form (AlK(SO4)2 * 12H2O). Potassium alum is formed by large, transparent crystals that...
Approved
Matched Description: … [L1070] It is an inorganic salt, also called potassium aluminum sulfate with a formula of AlK(SO4)2 that ... crystals that are used in different products like food or drugs as a buffer, neutralizing or forming agent …

Imdevimab

Imdevimab is a monoclonal antibody combined with casirivimab in Regeneron's antibody cocktail known as REGEN-COV2 for the treatment of COVID-19. This drug is a combination of antibodies derived from humanized VelocImmune® mice in addition to blood samples from patients who have recovered from COVID-19. These antibodies have been formulated to...
Approved
Experimental
Matched Description: … [L23524] In November 2021, the same indication was approved by the EMA. ... investigational recombinant human IgG1 monoclonal antibodies that, at this time, are not officially approved …
Matched Categories: … Approved Treatments for COVID-19 …

Regdanvimab

Regdanvimab (CT-P59) is a recombinant human IgG1 monoclonal antibody directed at the receptor binding domain (RBD) of the SARS-CoV-2 spike protein. It blocks the interaction between viral spike proteins and angiotensin-converting enzyme 2 (ACE2) that allows for viral entry into the cell, thereby inhibiting the virus' ability to replicate. Trials...
Approved
Investigational
Matched Categories: … Approved Treatments for COVID-19 …

Amiloride

A pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with...
Approved

Azathioprine

Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index.[A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of...
Approved
Matched Description: … mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an ... A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an …
Matched Products: … Truemed Group LLC …

Fomivirsen

Fomivirsen is a antisense 21 mer phosphorothioate oligonucleotide. It is an antiviral agent that was used in the treatment of cytomegalovirus retinitis (CMV) in immunocompromised patients, including those with AIDS. As a complementary nucleotide to the messenger RNA of the major immediate-early region proteins of human cytomegalovirus, it disrupts the...
Approved
Investigational
Withdrawn
Matched Description: … It is an antiviral agent that was used in the treatment of cytomegalovirus retinitis (CMV) in immunocompromised ... marketed under the trade name Vitravene for intravitreal injection and was the first antisense drug to be approved ... immediate-early region proteins of human cytomegalovirus, it disrupts the replication of the virus through an …

Levosimendan

Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels. It also relaxes vascular smooth muscle by opening adenosine triphosphate sensitive potassium channels. Levosimendan is used to manage acutely decompensated congestive heart failure.
Approved
Investigational

Anifrolumab

Anifrolumab, or MEDI-546, is a type 1 interferon receptor (IFNAR) inhibiting IgG1κ monoclonal antibody indicated in the treatment of adults with moderate to severe systemic lupus erythematosus.[A237074,L34929] The standard therapy for systemic lupus erythematosus consists of antimalarials like hydroxychloroquine, glucocorticoids like dexamethasone, and disease modifying antirheumatic drugs like methotrexate.[A237079,L34929] Three...
Approved
Investigational
Matched Description: … trials as potential treatments for systemic lupus erythematosus, but so far only anifrolumab has been approved …

Panobinostat

Panobinostat is an oral deacetylace (DAC) inhibitor approved on February 23, 2015 by the FDA for the treatment of multiple myeloma. The approval was accelerated based on progression-free survival, therefore confirmatory trials by the sponsor to demonstrate clinical efficacy in multiple myeloma treatment are in progress of being conducted. Panobinostat...
Approved
Investigational
Matched Description: … Panobinostat is an oral deacetylace (DAC) inhibitor approved on February 23, 2015 by the FDA for the ... non-selective histone deacetylase inhibitor (pan-HDAC inhibitor) and it is the most potent DAC inhibiting agent …

Ajmaline

An alkaloid found in the root of Rauwolfia serpentina, among other plant sources. It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials. Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a very...
Approved
Experimental
Matched Description: … An alkaloid found in the root of Rauwolfia serpentina, among other plant sources. ... It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac …

Bemotrizinol

Bemotrizinol, or bis-ethylhexyloxyphenol methoxyphenyl triazine, is an organic UV filter found in over-the-counter sunscreen products. It primarily absorbs UV-A rays. Compared to older broad-spectrum chemical agents, bemotrizinol is more more fat soluble (oil soluble in cosmetic oils) to aid in efficacy and broad-spectrum activity . It is claimed to be...
Approved
Matched Description: … Bemotrizinol, or bis-ethylhexyloxyphenol methoxyphenyl triazine, is an organic UV filter found in over-the-counter …

Lactic acid

A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste. It is produced by fermentation of a sugar source, such as...
Approved
Vet approved
Matched Description: … Lactic acid was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved …

Carbamide peroxide

Carbamide peroxide, also known as urea-hydrogen peroxide, is a water-soluble, white crystalline solid compound consisting of hydrogen peroxide and urea. As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products. Some adverse effects of carbamide peroxide as a dental bleaching agent include...
Approved
Matched Description: … of this ingredient as an oral wound healing agent [L1976]. ... The FDA considers carbamide peroxide to be safe in oral mucosal injury drug products as an oral wound ... Some adverse effects of carbamide peroxide as a dental bleaching agent include dentin sensitivity and …

Glycerin

A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Approved
Investigational
Matched Description: … A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. …
Matched Products: … An Adc Egf Wrinkle Eye ... An Adc Sp Intensive Wrinkle Eye ... Pro Radiance Renascent An Infinite Energizer …

Leflunomide

Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous. Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.
Approved
Investigational
Matched Description: … Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999. …
Matched Products: … Truemed Group LLC …

Isosorbide dinitrate

A vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.
Approved
Investigational
Matched Products: … Truemed Group LLC …

Pyridoxal phosphate

This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine).
Approved
Investigational
Nutraceutical

Benzethonium

Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1-0.2 %, which are safe and effective concentrations for the compound specified by the U.S. Food and Drug Administration (FDA)....
Approved

Dimethicone 410

Dimethicone is a silicone-based polymer used as a moisturizer in different skin OTC products. It is formed by repeated polymeric units of -(CH3)2SiO- with a terminal trimethyl siloxy unit. It is currently recognized by the FDA as a skin protectant OTC ingredient for human use in a concentration of 1-30%....
Approved

Ataluren

Ataluren is a novel, orally administered drug that targets nonsense mutations. Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and older who are able to walk. More specifically, ataluren is used in the small group of patients whose...
Approved
Investigational
Matched Description: … Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in ... More specifically, ataluren is used in the small group of patients whose disease is caused by a specific …

DL-dimyristoylphosphatidylcholine

A synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes. It is used in commercial drug preparations to solubilize drugs for injection
Approved

Fluticasone propionate

Fluticasone propionate is a synthetic glucocorticoid[F4355,F4358][FDA Label]. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications[F4355,F4358][FDA Label]. Fluticasone propionate was first approved in 1990 .
Approved
Matched Description: … Fluticasone propionate was first approved in 1990[L5962]. …
Matched Categories: … Corticosteroids, Potent (Group III) …

Sonidegib

Sonidegib is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) developed as an anticancer agent by Novartis. It was FDA approved in 2015 for the treatment of basal cell carcinoma.
Approved
Investigational
Matched Description: … agent by Novartis. ... It was FDA approved in 2015 for the treatment of basal cell carcinoma. ... Sonidegib is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) developed as an anticancer …

Dotatate

Approved
Experimental
Matched Categories: … Radioactive Diagnostic Agent …
Displaying drugs 26 - 50 of 9336 in total