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Displaying drugs 26 - 50 of 15016 in total

Etanercept

Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational
Matched Description: … Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell ... [L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region ... variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … BENEPALI 50MG IN FER ... BENEPALI 25MG ILO IN FER ... ERELZI 25MG ILO IN FER …

Mucor circinelloides f. circinelloides

Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. circinelloides …
Matched Description: … Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing. …

Insulin glulisine

Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … can result in symptoms such as fatigue, headache, blurred vision, and increased thirst. ... glucose, high blood sugar eventually causes cellular resistance to endogenous insulin, and in the long ... In the long term, elevated blood sugar levels increase the risk of heart attack, stroke, and diabetic …
Matched Categories: … Drugs Used in Diabetes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … APIDRA 100 U/ML- SOLUTION FOR INJECTION IN VIAL ... APIDRA 100 Units/ml Solution for Injection in vial ... APIDRA SOLOSTAR 100 UNITS/ML, SOLUTION FOR INJECTION IN A PRE-FILLED PEN …

Lixisenatide

Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM). It is sold by Sanofi-Aventis under the brand name Adlyxin in the US and Lyxumia in the EU. Adlyxin recieved FDA approval July 28, 2016.
Approved
Matched Description: … It is sold by Sanofi-Aventis under the brand name Adlyxin in the US[L763] and Lyxumia in the EU. ... Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes …
Matched Mixtures name: … LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) ... LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) ... Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled pen …
Matched Categories: … Drugs Used in Diabetes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin glargine and lixisenatide …
Matched Products: … LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG (50mcg/mL) ... LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 20MCG (100mcg/mL) …

Galcanezumab

Galcanezumab is a humanized monoclonal antibody developed by Eli Lilly and Company against human calcitonin gene-related peptide (CGRP). Although several small-molecule CGRP receptor antagonists have been developed, humanized monoclonal antibodies like galcanezumab are specifically designed to selectively bind to CGRP entities with high potency. Given this target specificity, lack of...
Approved
Investigational
Matched Description: … [A33112] Galcanezumab was approved by the FDA in September 2018, and is indicated for the preventive ... A pregnancy exposure registry has been established to evaluate the safety of this drug in pregnant women ... promising safety and tolerability. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … EMGALITY SOLUTION FOR INJECTION IN PRE-FILLED PEN 120 MG/ML ... Pontevia 120 mg solution for injection in pre-filled pen ... Pontevia 120 mg solution for injection in pre-filled syringe …

Evolocumab

Evolocumab is a monoclonal antibody designed for the treatment of hyperlipidemia by Amgen. It is a subcutaneous injection approved by the FDA for individuals on maximum statin therapy who still require additional LDL-cholesterol lowering. It is approved for both homozygous and heterozygous familial cholesterolemia as an adjunct to other first-line...
Approved
Matched Description: … surface, resulting in more LDL receptors on the surface of the liver to remove LDL-C from the blood. ... Evolocumab is designed to bind to PCSK9 and inhibit PCSK9 from binding to LDL receptors on the liver ... It is approved for both homozygous and heterozygous familial cholesterolemia as an adjunct to other first-line …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … REPATHA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 140MG/ML ... Repatha Solution for Injection in Pre-filled Syringe 140mg/mL (evolocumab) ... REPATHA SOLUTION FOR INJECTION IN PRE-FILLED AUTOINJECTOR 140MG/ML …

Aflibercept

Aflibercept is a recombinant protein composed of the binding domains of two human vascular endothelial growth factor (VEGF) receptors, VEGFR1 and VEGFR2, fused with the Fc region of human immunoglobulin gamma 1 (IgG1). Structurally, Aflibercept is a dimeric glycoprotein with a protein molecular weight of 96.9 kilo Daltons (kDa). It...
Approved
Matched Description: … it was approved by the FDA and EMA in August 2012 and February 2013, respectively. ... macular edema, and diabetic retinopathy in August 2023. ... preterm infants in February 2023 and for the treatment of wet age-related macular degeneration, diabetic …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … EYLEA 40MG/ML SOLUTION FOR INJECTION IN VIAL ... EYLEA SOLUTION FOR INJECTION IN VIAL 2MG ... EYLEA SOLUTION FOR INJECTION IN PREFILLED SYRINGE 2MG …

Adalimumab

Adalimumab is a subcutaneously administered biological disease modifier for the treatment of rheumatoid arthritis and other chronic debilitating diseases mediated by tumor necrosis factor.[A39984,A39999] It was originally launched by Abbvie in the U.S. and approved in 2002 by the FDA. This drug is frequently known as Humira. It is produced...
Approved
Experimental
Matched Description: … [A39984,A39999] It was originally launched by Abbvie in the U.S. and approved in 2002 by the FDA. ... - which was approved in August 2022 -,[L42935] and adalimumab-aacf - which was approved in October 2023 ... This drug is available in a prefilled syringe form and convenient pen form for subcutaneous self-administered …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … HULIO 40MG ILO IN FER ... AMGEVITA 40 mg/0.8 ml solution for injection in pre-filled syringe ... IDACIO SOLUTION FOR INJECTION IN PRE-FILLED PEN 40MG/0.8ML …

Tick-borne encephalitis vaccine (whole virus, inactivated)

Tick-borne encephalitis (TBE) is a disease caused by the TBE virus (TBEV), transmitted by ticks from the genus Ixodes. The disease course is variable. Some patients will be asymptomatic or experience a mild febrile illness, while others will experience the full course including neurological symptoms. TBE often manifests in a...
Approved
Matched Description: … and then propagated in chicken embryo fibroblast (CEF) cells, since the 1990's, the whole process has ... Europe, first approved in 1976. ... been carried out in CEF cells only. …
Matched Products: … FSME-Immun 0,25 ml Junior Injektionssuspension in einer Fertigspritze ... FSME-Immun 0,5 ml Erwachsene Injektionssuspension in einer Fertigspritze …

Tinzaparin

Tinzaparin is a low molecular weight heparin (LMWH), produced by enzymatic depolymerization of unfractionated heparin from porcine intestinal mucosa. It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. Tinzaparin is composed of molecules with and without a special site for high affinity binding...
Approved
Matched Description: … It is an anticoagulant and considered an antithrombotic. ... It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. ... Tinzaparin is composed of molecules with and without a special site for high affinity binding to antithrombin …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …
Matched Products: … innohep 8.000 IE/0,4 ml Injektionslösung in einer Fertigspritze ... innohep 10.000 IE/0,5 ml Injektionslösung in einer Fertigspritze ... innohep 12.000 IE/0,6 ml Injektionslösung in einer Fertigspritze …

Polyethylene glycol

Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.[A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary...
Approved
Vet approved
Matched Description: … PEGs differ in their physical and chemical properties depending on their molecular weight: PEGs are liquids ... [L11812] PEG 3350 is also used for cleansing of the colon in preparation for colonoscopy in adults. ... bowel cleansing for preparation in colonoscopy. …
Matched Mixtures name: … Polyethylene Glycol-3350, Sodium Chloride, Potassium Chloride and Sodium Bicarbonate ... PEG-3350, sodium chloride, sodium bicarbonate and potassium chloride ... PEG-3350, sodium chloride, sodium bicarbonate and potassium chloride …
Matched Categories: … Alimentary Tract and Metabolism ... Compounds used in a research, industrial, or household setting …
Matched Products: … Mix-In Laxative Packets ... Up and Up Powderlax ... Berkley and Jensen Clearlax …

Satralizumab

Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL-6) receptors, similar to tocilizumab, which is produced in Chinese hamster ovary cells and based on an IgG2 framework. Satralizumab is used in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune inflammatory disorder of the central...
Approved
Matched Description: … [eculizumab] in June 2019 and [inebilizumab] in June 2020). ... [A218551] It received subsequent approvals in Switzerland and Japan,[A218551] and was approved for use ... in part, by IL-6, including increased production of anti-aquaporin-4 (AQP4) autoantibodies and increased …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … ENSPRYNG SOLUTION FOR INJECTION IN PREFILLED SYRINGE 120MG/1ML ... ENSPRYNG 120 mg/1ml solution for injection in pre-filled syringe …

Ferric derisomaltose

Iron deficiency is an extremely common condition and is the most frequent cause of anemia worldwide. Iron deficiency results when iron intake, iron stores, and loss of iron from the body do not adequately support production of erythrocytes, also known as red blood cells. Though it is generally considered non...
Approved
Matched Description: … [A190528] Ferric derisomaltose is a form of iron used in the treatment of iron deficiency. ... This drug is a complex of iron (III) hydroxide and derisomaltose. ... Ferric derisomaltose was developed by Pharmacosmos Therapeutics ad was granted FDA approval in January …
Matched Products: … Monofer 100 mg/ml solution for injection/infusion in vials ... Monofer 100mg/ml solution for injection/infusion in ampoules …

Ixekizumab

Ixekizumab is a humanized immunoglobulin G subclass 4 (IgG4) monoclonal antibody (mAb) against interleukin-17A (IL-17A) and prevents it from interacting with the IL-17A receptor. As IL-17A is a pro-inflammatory cytokine involved in inflammation and immune responses, blocking its effect is beneficial for use in inflammatory conditions. In particular, IL-17A has...
Approved
Investigational
Matched Description: … As IL-17A is a pro-inflammatory cytokine involved in inflammation and immune responses, blocking its ... Ixekizumab is produced by recombinant DNA technology in a recombinant mammalian cell line and purified ... In particular, IL-17A has been found to be implicated in a variety of autoimmune diseases including Rheumatoid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Taltz 80mg solution for injection in pre-filled pen ... Taltz 80mg solution for injection in pre-filled syringe ... TALTZ SOLUTION FOR INJECTION IN PRE-FILLED PEN 80 mg/ml …

Methoxy polyethylene glycol-epoetin beta

Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin. ESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia.
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Products: … MIRCERA SOLUTION FOR INJECTION IN PRE FILLED SYRINGE, 200MCG/0.3ML ... MIRCERA SOLUTION FOR INJECTION IN PRE FILLED SYRINGE, 150MCG/0.3ML ... MIRCERA SOLUTION FOR INJECTION IN PRE FILLED SYRINGE, 100MCG/0.3ML …

Certolizumab pegol

Certolizumab pegol is a pegylated monoclonal antibody against the tumor necrosis factor-alpha (TNF-alpha). It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 kDa polyethylene glycol moiety replacing the Fc antibody region. The absence of the Fc region was ideated...
Approved
Matched Description: … [A176606] It was developed and manufactured by UCB Pharma, first FDA approved in 2008[L45018] and updated ... significantly more affordable when compared to other existing TNF-alpha therapies as it can be done directly in ... [A176606] Certolizumab does not require glycosylation for active function and hence, its production …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … CIMZIA 200 MG ILO IN FER ... CIMZIA 200MG ILO IN FER …

Guselkumab

Guselkumab is a human immunoglobulin G1 lambda (IgG1λ) monoclonal antibody that selectively blocks interleukin-23. IL-23 is an inflammatory cytokine that activates the CD4+ T-helper (Th17) cell pathway to mediate the inflammatory cascade that induces psoriatic plaque formation . In clinical trials, guselkumab demonstrated improved skin clearance and symptomatic improvements in...
Approved
Investigational
Matched Description: … In clinical trials, guselkumab demonstrated improved skin clearance and symptomatic improvements in dermatological ... Developed by Janssen, the subcutenous injection form of guselkumab was approved in July 2017 under the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
Matched Products: … TREMFYA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML ... TREMFYA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 100MG/1ML …

Norepinephrine

Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Description: … It is also found in plants and is used pharmacologically as a sympathomimetic. ... projection system in the brain arising from the locus ceruleus. ... Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic …
Matched Categories: … Epinephrine and similars ... Adrenergic and Dopaminergic Agents ... Alpha-and Beta-adrenergic Agonists …
Matched Products: … Norepinephrine Bitartrate In Sodium Chloride ... Norepinephrine Bitartrate In 5% Dextrose Injection …

Neisseria meningitidis group C capsular polysaccharide tetanus toxoid conjugate antigen

Approved
Matched Products: … NeisVac-C Injektionssuspension in einer Fertigspritze …

Gadobutrol

Gadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. Due to its physicochemical properties, gadobutrol is formulated at twice the gadolinium ion concentration compared to other GBCA and thus requires a lesser...
Approved
Matched Description: … magnetic resonance imaging (MRI) in adults and children older than 2 years of age. ... a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in ... properties, gadobutrol is formulated at twice the gadolinium ion concentration compared to other GBCA and …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Gadograf 1,0 mmol/ml Injektionslösung in Fertigspritzen ... Gadovist 1,0 mmol/ml Injektionslösung in Fertigspritzen/Patronen …

Varicella zoster vaccine (live/attenuated)

Live attenuated zoster vaccine is available as two products: Zostavax for the prevention of shingles in immunocompetent people over the age of 50, and Varivax for the prevention of chickenpox in individuals 12 months of age and older. While the two vaccines contain the same immunological components and provide protection...
Approved
Matched Description: … efficacy in preventing postherpetic neuralgia in patients 70 years and older and 91% efficacy in patients ... immunocompetent people over the age of 50, and Varivax for the prevention of chickenpox in individuals ... First approved in May 2006 by the Food and Drug Administration, Zostavax was the first vaccine available …
Matched Mixtures name: … Priorix - Tetra Pulver in einer Durchstechflasche und Lösungsmittel in einer Fertigspritze zur Herstellung ... PROQUAD® ( Measles, Mumps, Rubella AND Varicella (Oka/Merck) Virus Vaccine Live, MSD) LYOPHILIZED VACCINE …
Matched Products: … VARIVAX Pulver und Lösungsmittel zur Herstellung einer Injektionssuspension in einer Fertigspritze ... Varilrix Pulver und Lösungsmittel zur Herstellung einer Injektionssuspension in einer Fertigspritze …

Dimethicone

Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants. It is used in a number of health and beauty products including hair care...
Approved
Matched Description: … , leave-in conditioner, and de-tangling products. ... It is used in a number of health and beauty products including hair care products such as shampoo, conditioner ... Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical …
Matched Mixtures name: … QYO QYO Tangerine Bright Moist All In One Cream ... Childrens Mylicon All in One Tummy Relief for Kids ... A and D …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Basic Ointments and Protectants ... Scabicides and Pediculicides ... Skin and Mucous Membrane Agents ... Scabicides, Insecticides and Repellents …
Matched Products: … Midnight Cinema LA Belle In Rouge 01. Dancing In Monaco ... Kendall 2-in-1 Cleanser ... Mizon All In One Snail Repair …

Benzoic acid

A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid. As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. This leads...
Approved
Investigational
Matched Description: … It is conjugated to GLYCINE in the liver and excreted as hippuric acid. ... This leads to excretion of these amino acids and a decrease in ammonia levels. ... Total Positive and Negative Syndrome Scale scores dropped by 21% compared to placebo. …
Matched Mixtures name: … Sodium Phenylacetate and Sodium Benzoate ... Sodium Phenylacetate and Sodium Benzoate ... Sodium Phenylacetate and Sodium Benzoate …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... caffeine and sodium benzoate ... sodium benzoate and sodium phenylacetate …
Matched Products: … S Panax All In One Mist …

Oxybuprocaine

Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.
Approved
Investigational
Matched Description: … and otolaryngology. ... Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology ... Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases …
Matched Mixtures name: … Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride …
Matched Products: … Benoxinat 1% - Lösung zur Anästhesie in der Oto-Rhino-Laryngologie …

Hepatitis B Vaccine (Recombinant)

Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Description: … 70% in the general population and a carrier rate of up to 20%. ... Certain population subgroups in these areas, however, are at high risk (see Indications and Clinical ... In Canada, the United States and Northern Europe, 4% to 6% of the population are infected during their …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Bacterial and viral vaccines, combined ... haemophilus influenzae B and hepatitis B …
Matched Products: … ENGERIX-B SUSPENSION FOR INJECTION IN PREFILLED SYRINGE 20MCG/ML ... ENGERIX-B SUSPENSION FOR INJECTION IN PREFILLED SYRINGE 10mcg/0.5ml ... ENGERIX-B 20 Mikrogramm/1 ml Injektionssuspension in einer Fertigspritze …
Displaying drugs 26 - 50 of 15016 in total