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Displaying drugs 476 - 500 of 7673 in total

Denosumab

Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption via inhibiting RANK-mediated activation of osteoclasts. It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss. Chemically, it consists of 2 heavy...
Approved

Alfuzosin

Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow. The prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases...
Approved
Investigational
Matched Products: … XATRAL SR TABLET 5 mg ... Xatral SR 5 mg Filmtabletten ... Alfuzosin Stada 5 mg - Retardtabletten …

Sargramostim

Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.
Approved
Investigational

Mannitol busulfan

Mm has been used in trials studying the treatment of Cocaine Dependence and Diabetes Mellitus, Type 2.
Approved
Investigational
Matched Iupac: … (2R,3R,4R,5R)-2,3,4,5-tetrahydroxy-6-(methanesulfonyloxy)hexyl methanesulfonate …

Telithromycin

Telithromycin, a semi-synthetic erythromycin derivative, belongs to a new chemical class of antibiotics called ketolides. Ketolides have been recently added to the macrolide-lincosamide-streptogramin class of antibiotics. Similar to the macrolide antibiotics, telithromycin prevents bacterial growth by interfering with bacterial protein synthesis. Telithromycin binds to the 50S subunit of the 70S...
Approved

Etanercept

Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational

Lithium citrate

Approved

Vinorelbine

Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) . It was initially approved in the USA in 1990's for the treatment of NSCLC . It is a third-generation vinca alkaloid. The introduction...
Approved
Investigational
Matched Synonyms: … 5'-Noranhydrovinblastine …
Matched Iupac: … methoxycarbonyl)-1,10-diazatetracyclo[12.3.1.0^{3,11}.0^{4,9}]octadeca-3(11),4,6,8,15-pentaen-12-yl]-10-hydroxy-5- …
Matched Salts cas: … 125317-39-7 …
Matched Products: … VINORELBINA SOLUCION INYECTABLE 50 MG / 5 ML ... VİNALBİN 50 MG/5 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... NAVELBINE 50MG/5 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …

Trichothecium roseum

Trichothecium roseum is a fungus which can provoke allergic reactions. Trichothecium roseum extract is used in allergenic testing.
Approved

Acrothecium robustum

Acrothecium robustum is a fungus which can provoke allergic reactions. Acrothecium robustum extract is used in allergenic testing.
Approved

Plasminogen

Plasminogen is a pro-enzyme (i.e. a zymogen) which is cleaved to form plasmin - also known as fibrinolysin - as part of the fibrinolytic pathway that breaks down fibrin blood clots. This pathway is activated when a clot is no longer needed or to prevent a clot from extending beyond...
Approved

Bilastine

Bilastine is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.
Approved
Investigational

Cyclobenzaprine

Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond.[A185039,A184982] Since its approval, it has...
Approved
Matched Synonyms: … (3-Dibenzo[a,d]cyclohepten-5-ylidene-propyl)-dimethyl-amine …
Matched Mixtures name: … Therabenzaprine-90-5 …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Matched Products: … TONALGEN® COMPRIMIDOS 5 MG ... TENSODOX ® 5 MG TABLETAS RECUBIERTAS. ... FLESSİ 5 MG FİLM KAPLI TABLET, 30 ADET …

Aluminum zirconium tetrachlorohydrex gly

Aluminum zirconium tetrachlorohydrex gly is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.
Approved
Matched Products: … Lady Speed Stick 24/7 …

Lenzumestrocel

Approved
Investigational
Matched International brands: … NEURONATA-R …
Matched Synonyms: … NEURONATA-R …

Pidolic acid

Pidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various chemical pathways [A32991, L2729]. Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism...
Approved
Investigational
Matched Synonyms: … 5-L-oxoproline ... 5-oxo-L-proline ... (−)-2-pyrrolidone-5-carboxylic acid …
Matched Iupac: … (2S)-5-oxopyrrolidine-2-carboxylic acid …

Hexachlorophene

A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
Approved
Withdrawn
Matched Synonyms: … 2,2'-dihydroxy-3,5,6,3',5',6'-hexachlorodiphenylmethane …

Methylphenobarbital

A barbiturate that is metabolized to phenobarbital. It has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital.
Approved
Matched Synonyms: … 5-ethyl-1-methyl-5-phenylbarbituric acid ... 5-Ethyl-1-methyl-5-phenyl-pyrimidine-2,4,6-trione ... 5-ethyl-1-methyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione …
Matched Iupac: … 5-ethyl-1-methyl-5-phenyl-1,3-diazinane-2,4,6-trione …

Methsuximide

Mesuximide (or methsuximide) is an anticonvulsant medication. It is sold by Pfizer under the name Petinutin.
Approved

Apadamtase alfa

Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Description: … TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% …

Melatonin

Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. In mammals, melatonin is produced by the pineal gland. The pineal gland is small endocrine gland, about...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … 5-methoxy-N-acetyltryptamine ... N-Acetyl-5-methoxytryptamine ... N-[2-(5-methoxyindol-3-yl)ethyl]acetamide …
Matched Iupac: … N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide …
Matched Products: … Mellozzan 5 mg Tabletten ... Melatonin Rapid Release Gelcaps 5 mg …

Quinine

An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in...
Approved
Matched Synonyms: … (R)-(−)-quinine ... (R)-(6-methoxyquinolin-4-yl)((2S,4S,8R)-8-vinylquinuclidin-2-yl)methanol …
Matched Iupac: … (R)-[(1S,2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol …
Matched Salts cas: … 752-72-7 ... 804-63-7 ... 6119-47-7 …

Ensulizole

Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly...
Approved
Matched Description: … Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that …
Matched Mixtures name: … Pro Retinol 100% Vegetal Fluide Defenseur ... Careone Anti Aging Vitamin Complex 7 in 1 ... Elements Anti Aging Vitamin Complex 7 In 1 …

Alprazolam

Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.[L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole.[L34783, L34788] Benzodiazepine treatment should be stopped gradually by tapering down a patient's dose to avoid withdrawal symptoms. Alprazolam's adverse...
Approved
Illicit
Investigational
Matched Products: … XANAX 1 MG TABLET, 100 ADET …

Capsicum oleoresin

Capsicum oleoresin is an oily organic resin derived from the fruit of plants in the Capsicum genus, such as chilli peppers. When the plants are finely ground, capsicum oleoresin is formed after the extraction process of capsaicin using oragnic solvents such as ethanol. It is commonly used as a culinary...
Approved
Displaying drugs 476 - 500 of 7673 in total