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Displaying drugs 476 - 500 of 2461 in total
Lorukafusp alfa is under investigation in clinical trial NCT01334515 (Biological Therapy, Sargramostim, and Isotretinoin in Treating Patients With Relapsed or Refractory Neuroblastoma).
Investigational
Matched Synonyms: … Lorukafusp alfa
Matched Name: … Lorukafusp alfa
Matched Description: … , and Isotretinoin in Treating Patients With Relapsed or Refractory Neuroblastoma). ... Lorukafusp alfa is under investigation in clinical trial NCT01334515 (Biological Therapy, Sargramostim …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Edodekin alfa is under investigation in clinical trial NCT01468896 (Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That Is Recurrent, Metastatic, or Cannot Be Removed by Surgery).
Investigational
Matched Synonyms: … Edodekin alfa
Matched Name: … Edodekin alfa
Matched Description: … Edodekin alfa is under investigation in clinical trial NCT01468896 (Cetuximab and Recombinant Interleukin ... -12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That Is Recurrent, Metastatic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Efmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia).
Investigational
Matched Synonyms: … Efmarodocokin alfa ... CH2(N67>G(227)))-(147-377), DIMER (156-156':159-159')-BISDISULFIDE, PRODUCED IN CHO CELLS, GLYCOFORM ALFA
Matched Name: … Efmarodocokin alfa
Matched Description: … and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia). ... Efmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety …
Modakafusp alfa is under investigation in clinical trial NCT03215030 (A Study to Investigate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of TAK-573 in Participants With Refractory Multiple Myeloma (MM)).
Investigational
Matched Synonyms: … Modakafusp alfa
Matched Name: … Modakafusp alfa
Matched Description: … , Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of TAK-573 in Participants With Refractory ... Modakafusp alfa is under investigation in clinical trial NCT03215030 (A Study to Investigate the Safety …
Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding episodes in patients with hemophilia A. The use of FVIII replacement products is beneficial in patients with hemophilia A; however, their quality...
Approved
Investigational
Matched Name: … Efanesoctocog alfa
Matched Description: … [A257464] Efanesoctocog alfa was designed to have an extended half-life, and to surpass the half-life ... To extend the half-life of FVIII, efanesoctocog alfa is fused to dimeric Fc, a D'D3 domain of VWF, and ... routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tividenofusp alfa, also known as DNL-310, is a brain-penetrant enzyme replacement therapy being investigated for the treatment of Hunter syndrome.
Investigational
Matched Name: … Tividenofusp alfa
Matched Description: … Tividenofusp alfa, also known as DNL-310, is a brain-penetrant enzyme replacement therapy being investigated …
Levonorgestrel (LNG) is a synthetic progestogen similar to Progesterone used in contraception and hormone therapy.[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. Some of these devices...
Approved
Investigational
Matched Description: … Some of these devices are known as Jaydess, Kyleena, and Mirena. ... Levonorgestrel (LNG) is a synthetic progestogen similar to [Progesterone] used in contraception and hormone ... [A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as …
Matched Mixtures name: … Levonorgestrel and Ethinyl Estradiol and Ethinyl Estradiol ... Levonorgestrel and Ethinyl Estradiol and Ethinyl Estradiol ... Levonorgestrel and Ethinyl Estradiol and Ethinyl Estradiol …
Matched Categories: … levonorgestrel and estrogen ... levonorgestrel and estrogen ... Genito Urinary System and Sex Hormones ... levonorgestrel and ethinylestradiol ... levonorgestrel and ethinylestradiol …
Matched Products: … ONE-AND-ONE …
Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. Darunavir is being...
Approved
Matched Synonyms: … [(S)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-2-hydroxy-1-((R)-phenylmethyl)-propyl]-carbamic acid ... {(1S,2R)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-1-benzyl-2-hydroxy-propyl}-carbamic acid (3R,3aS …
Matched Description: … [A191682] Clinical trials are underway and are expected to conclude in August 2020.[L12066] …
Matched Categories: … Carboxylic Acids ... darunavir and ritonavir ... darunavir and cobicistat ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Darunavir 600 and 800 mg …
Approved
Experimental
Matched Synonyms: … 2,3-Dimercaptosuccinic acid ... 2,3-Dimercaptobutanedioic acid
Matched Name: … Dimercaptosuccinic acid
Matched Iupac: … 2,3-disulfanylbutanedioic acid
Matched Salts name: … Sodium dimercaptosuccinic acid
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids
Matched Products: … Dimercaptosuccinic Acid DMSA …
Andexanet alfa is a recombinant human coagulation Factor Xa that promotes blood coagulation. It was developed by Portola Pharmaceuticals and was approved in in May 2018. It is marketed as Andexxa for intravenous injection or infusion and is indicated for the reversal of anticoagulation in combination with rivaroxaban and apixaban...
Approved
Investigational
Matched Synonyms: … Andexanet alfa
Matched Name: … Andexanet alfa
Matched Description: … Andexanet alfa is currently under regulatory review by the European Union and is undergoing clinical ... Andexanet alfa works by binding to Factor Xa inhibitors and prevent them from interacting with endogenous ... containing Gla: via this truncation, andexanet alfa is unable to bind to membrane surfaces and assemble …
Matched Categories: … Amino Acids, Peptides, and Proteins ... andexanet alfa ... Enzymes and Coenzymes …
Approved
Matched Synonyms: … Acido oxidronico ... Oxidronic acid ... Acidum oxidronicum …
Matched Name: … Oxidronic acid
Matched Iupac: … [hydroxy(phosphono)methyl]phosphonic acid
Approved
Experimental
Matched Name: … Chloric acid
Matched Iupac: … chloric acid
Matched Mixtures name: … Polyethylene Glycol 3350 and electrolytes - Unflavored …
Matched Products: … Hemodialysis Acid Concentrate …
Taliglucerase alfa is the recombinant active form of the human lysosomal enzyme, β-glucocerebrosidase. It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's disease.
Approved
Investigational
Matched Synonyms: … Taliglucerase alfa
Matched Name: … Taliglucerase alfa
Matched Description: … It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's ... Taliglucerase alfa is the recombinant active form of the human lysosomal enzyme, β-glucocerebrosidase …
Matched Categories: … taliglucerase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties. Having been developed in the 1980s by GlaxoSmithKline and approved by the US FDA since January 1991, ondansetron has...
Approved
Withdrawn
Matched Description: … cisplatin, and has reported anxiolytic and neuroleptic properties. ... Commonly formulated as oral tablets, orally disintegrating tablets (ODT), and injections, and available ... ondansetron has demonstrated a long history of use and efficacy. …
Matched Categories: … Antiemetics and Antinauseants …
Matched Products: … Ondansetron and Dextrose ... Ondansetron Hydrochloride and Dextrose ... Ondansetron hydrochloride and dextrose …
Lactobacillus plantarum is a member of Lactobacillus, or lactic acid bacteria, that it is widely used in the food industry as a microbial starter and probiotic microorganism. It is considered to be one of versatile species that carry out fermentative and metabolic processes, while exhibiting an antagonistic activity against pathogenic...
Investigational
Matched Description: … , bacteriocins, and antimicrobial peptides [A27208]. ... in the food industry as a microbial starter and probiotic microorganism. ... while exhibiting an antagonistic activity against pathogenic and spoilage microorganisms. …
Matched Products: … Kimchi Lactic Acid 1000 …
A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Approved
Investigational
Matched Description: … It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). ... A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon …
Matched Mixtures name: … Lamivudine and Zidovudine ... Lamivudine and Zidovudine ... Lamivudine and Zidovudine …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleic Acid Synthesis Inhibitors ... lamivudine and abacavir ... stavudine and lamivudine ... zidovudine and lamivudine …
Matched Products: … Lamivudine and Zidovudine …
An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. (From Martindale, The Extra Pharmacopoeia, 30th ed, p16)
Approved
Matched Synonyms: … Flufenamic acid ... acide flufénamique ... Acidum flufenamicum …
Matched Name: … Flufenamic acid
Matched Iupac: … 2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid
Matched Description: … An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. ... It is used in musculoskeletal and joint disorders and administered by mouth and topically. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic ... Carboxylic Acids ... flufenamic acid
Investigational
Matched Synonyms: … maltase, aglucosidase alfa) produced in chinese hamster ovary (cho) cells, glycoform alfa ... insulin-like growth factor ii fusion protein with glycyl-l-alanyl-l-prolyl-human lysosomal alpha-glucosidase (acid
Matched Name: … Reveglucosidase alfa
Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent.
Approved
Matched Synonyms: … Interferon alfa-2b ... Interferon alfa-2b (recombinant) ... Interferon alfa-2b, recombinant …
Matched Name: … Interferon alfa-2b …
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... A type I interferon consisting of 165 amino acid residues with arginine in position 23. …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alfa Interferons ... Antineoplastic and Immunomodulating Agents ... interferon alfa-2b ... Intercellular Signaling Peptides and Proteins …
Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis. Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain, or first line as a topical treatment of corticosteroid responsive dermatoses. Triamcinolone is more...
Approved
Vet approved
Matched Description: … Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and
Matched Mixtures name: … Nystatin and Triamcinolone ... Nystatin and Triamcinolone ... Nystatin and Triamcinolone …
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... triamcinolone and antiseptics ... triamcinolone and antibiotics ... triamcinolone and antiinfectives …
Matched Products: … Up and Up Nasal Allergy ... Foster and Thrive 24 Hour Nasal Allergy …
Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of...
Approved
Vet approved
Withdrawn
Matched Description: … Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental ... [L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today. ... [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two …
Matched Mixtures name: … Pre and Post Sx Pouch ... Oral Cleansing and Suctioning System, q2 ... QCare Rx Oral Cleansing and Suctioning System …
Matched Categories: … Alimentary Tract and Metabolism ... Biguanides and Amidines ... Antiseptics and Disinfectants ... Mouthwashes and Gargles ... chlorhexidine and cetylpyridinium …
Matched Products: … Foster and Thrive ... 3M AVAGARD 9232 ANTISEPTIC HAND AND BODY WASH CLORHEXIDINE GLUCONATE 2% W/W SOLUTION BOTTE . …
Investigational
Matched Synonyms: … Orotic acid ... Acido orotico ... Acidum oroticum …
Matched Name: … Orotic acid
Matched Iupac: … 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid
Matched Categories: … Acids, Heterocyclic …
A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.
Approved
Matched Synonyms: … Cromoglicic acid ... Cromoglycic acid ... Acido Cromoglicico …
Matched Name: … Cromoglicic acid
Matched Iupac: … 5-{3-[(2-carboxy-4-oxo-4H-chromen-5-yl)oxy]-2-hydroxypropoxy}-4-oxo-4H-chromene-2-carboxylic acid
Matched Description: … It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect …
Matched Categories: … Alimentary Tract and Metabolism ... Decongestants and Antiallergics ... reproterol and sodium cromoglicate ... salbutamol and sodium cromoglicate ... cromoglicic acid
C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways. It does this through inhibition of several target proteases within...
Approved
Investigational
Matched Synonyms: … Conestat alfa
Matched Name: … Conestat alfa
Matched Description: … tPA and plasmin within the fibrinolytic pathway. ... The primary function of endogenous C1INH is to regulate the activation of the complement and contact ... Additionally, C4 and C2 cleavage occurs resulting in auto-activation of the complement system. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... conestat alfa ... Blood and Blood Forming Organs …
Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Synonyms: … Susoctocog alfa
Matched Name: … Susoctocog alfa
Matched Description: … Susoctocog alfa was approved by the FDA in October 2014 and is marketed under the brand name Obizur for ... Susoctocog alfa is a glycoprotein containing a 90 kDa heavy chain and a 80 kDa light chain with the naturally-occuring ... B domain replaced with a twenty-four amino acid linker. …
Matched Categories: … Blood and Blood Forming Organs ... susoctocog alfa
Displaying drugs 476 - 500 of 2461 in total