Displaying drugs 476 - 500 of 1826 in total
Vimseltinib
Investigational
Matched Synonyms: … 2-(isopropylamino)-3-methyl-5-(6-methyl-5-((2-(1-methyl-1h-pyrazol-4-yl)pyridin-4-yl)oxy)pyridin-2-yl ... 4(3h)-pyrimidinone, 3-methyl-2-((1-methylethyl)amino)-5-(6-methyl-5-((2-(1-methyl-1h-pyrazol-4-yl)-4- ... 3-methyl-2-((1-methylethyl)amino)-5-(6-methyl-5-((2-(1-methyl-1h-pyrazol-4-yl)-4-pyridinyl)oxy)-2-pyridinyl …
Matched Iupac: … 3-methyl-5-(6-methyl-5-{[2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl]oxy}pyridin-2-yl)-2-[(propan-2-yl)amino …
Matched Iupac: … 3-methyl-5-(6-methyl-5-{[2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl]oxy}pyridin-2-yl)-2-[(propan-2-yl)amino …
Amlodipine
Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched Synonyms: … (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate ... 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate …
Matched Iupac: … 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Amlodipine is commonly used in the treatment of high blood pressure and angina. ... Amlodipine has antioxidant properties and an ability to enhance the production of nitric oxide (NO), ... dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and …
Matched Mixtures name: … AMLODIPINE and VALSARTAN ... Amlodipine and Valsartan ... Amlodipine and Valsartan …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... nebivolol and amlodipine ... losartan and amlodipine ... aliskiren and amlodipine ... ramipril and amlodipine …
Matched Iupac: … 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Amlodipine is commonly used in the treatment of high blood pressure and angina. ... Amlodipine has antioxidant properties and an ability to enhance the production of nitric oxide (NO), ... dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and …
Matched Mixtures name: … AMLODIPINE and VALSARTAN ... Amlodipine and Valsartan ... Amlodipine and Valsartan …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... nebivolol and amlodipine ... losartan and amlodipine ... aliskiren and amlodipine ... ramipril and amlodipine …
Evofosfamide
TH-302 is a novel cancer therapeutic specifically activated under the low oxygen or "hypoxic" conditions typical of solid tumor cancer cells. TH-302 is a nitroimidazole-linked prodrug of a brominated derivative of an isophosphoramide mustard previously used in cancer drugs such as ifosfamide, cyclophosphamide, and glufosfamide. TH-302 has been shown, in...
Investigational
Matched Synonyms: … (1-methyl-2-nitro-1H-imidazol-5-YL)methyl N,N'-bis(2-bromoethyl)diamidophosphate ... (1-methyl-2-nitro-1H-imidazole-5-yl)methyl N,N'-bis(2-bromoethyl) diamidophosphate …
Matched Iupac: … (2-bromoethyl)({[(2-bromoethyl)amino][(1-methyl-2-nitro-1H-imidazol-5-yl)methoxy]phosphoryl})amine …
Matched Description: … TH-302 has been shown, in preclinical studies, to be both efficacious and well tolerated. ... of an isophosphoramide mustard previously used in cancer drugs such as ifosfamide, cyclophosphamide, and …
Matched Iupac: … (2-bromoethyl)({[(2-bromoethyl)amino][(1-methyl-2-nitro-1H-imidazol-5-yl)methoxy]phosphoryl})amine …
Matched Description: … TH-302 has been shown, in preclinical studies, to be both efficacious and well tolerated. ... of an isophosphoramide mustard previously used in cancer drugs such as ifosfamide, cyclophosphamide, and …
Oxibendazole
Oxibendazole is a polymerase inhibitor in phase III trials for the treatment of helminth intestinal infections.
Investigational
Vet approved
Matched Synonyms: … Methyl 5-propoxy-2-benzimidazolecarbamate ... Methyl 5-n-propoxy-2-benzimidazole carbamate ... 5-Propoxy-2-benzimidazolecarbamic acid methyl ester …
Matched Iupac: … methyl N-(6-propoxy-1H-1,3-benzodiazol-2-yl)carbamate …
Matched Iupac: … methyl N-(6-propoxy-1H-1,3-benzodiazol-2-yl)carbamate …
Mecobalamin
Approved
Investigational
Matched Synonyms: … Methyl vitamin B12 ... Methyl(III)cobalamin …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal ... Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil …
Matched Categories: … Blood and Blood Forming Organs ... Vitamin B12 and Folic Acid …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal ... Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil …
Matched Categories: … Blood and Blood Forming Organs ... Vitamin B12 and Folic Acid …
S-Methyl glutathione
Experimental
Matched Synonyms: … Glutathione S-methyl ester ... L-gamma-Glutamyl-S-methyl-L-cysteinylglycine …
Matched Name: … S-Methyl glutathione …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … S-Methyl glutathione …
Matched Categories: … Amino Acids, Peptides, and Proteins …
3-Methylthiofentanyl
3-Methyl-thiofentanyl is a fentanyl analog and an opioid analgesic that works by inducing central nervous system (CNS) depression.
Experimental
Illicit
Matched Synonyms: … 3-Methyl-thiofentanyl …
Matched Iupac: … N-{3-methyl-1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl}-N-phenylpropanamide …
Matched Description: … 3-Methyl-thiofentanyl is a [fentanyl] analog and an opioid analgesic that works by inducing central nervous …
Matched Iupac: … N-{3-methyl-1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl}-N-phenylpropanamide …
Matched Description: … 3-Methyl-thiofentanyl is a [fentanyl] analog and an opioid analgesic that works by inducing central nervous …
Canoctakin
Investigational
Matched Synonyms: … Interleukin 8 (synthetic human clone dncxcl8 increased-glycosaminoglycan binding isoform pa401) …
Methyl-D9-choline
Methyl-D9-choline is under investigation in clinical trial NCT01807910 (ER Stress in NAFLD).
Investigational
Matched Name: … Methyl-D9-choline …
Matched Description: … Methyl-D9-choline is under investigation in clinical trial NCT01807910 (ER Stress in NAFLD). …
Matched Description: … Methyl-D9-choline is under investigation in clinical trial NCT01807910 (ER Stress in NAFLD). …
Venadaparib
Investigational
Matched Synonyms: … 1(2h)-phthalazinone, 4-((3-((3-((cyclopropylamino)methyl)-1-azetidinyl)carbonyl)-4-fluorophenyl)methyl ... 4-((3-((3-((cyclopropylamino)methyl)-1-azetidinyl)carbonyl)-4-fluorophenyl)methyl)-1(2h)-phthalazinone …
Matched Iupac: … 4-[(3-{3-[(cyclopropylamino)methyl]azetidine-1-carbonyl}-4-fluorophenyl)methyl]-1,2-dihydrophthalazin …
Matched Iupac: … 4-[(3-{3-[(cyclopropylamino)methyl]azetidine-1-carbonyl}-4-fluorophenyl)methyl]-1,2-dihydrophthalazin …
Methscopolamine bromide
A muscarinic antagonist used to study binding characteristics of muscarinic cholinergic receptors.
Approved
Matched Synonyms: … Hyoscine methyl bromide ... (−)-scopolamine methyl bromide ... Scopolamine methyl bromide …
Etevritamab
Investigational
Matched Synonyms: … RECEPTOR, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1, ERBB1, HER1, HER-1, ERBB) VARIANT III (EGFRVIII)) AND …
Vodobatinib
Investigational
Matched Synonyms: … 2-chloro-6-methyl-n'-(4-methyl-3-(2-(quinolin-3-yl)ethynyl)benzoyl)benzohydrazide ... Benzoic acid, 2-chloro-6-methyl-, 2-(4-methyl-3-(2-(3-quinolinyl)ethynyl)benzoyl)hydrazide ... 4-methyl-3-quinolin-3-yl-ethynyl benzoic acid n'-(2-chloro-6-methylbenzoyl)hydrazide …
Matched Iupac: … 2-chloro-6-methyl-N'-{4-methyl-3-[2-(quinolin-3-yl)ethynyl]benzoyl}benzohydrazide …
Matched Iupac: … 2-chloro-6-methyl-N'-{4-methyl-3-[2-(quinolin-3-yl)ethynyl]benzoyl}benzohydrazide …
1-Methylhistidine
Experimental
Matched Synonyms: … 1-methyl-L-histidine ... N(tele)-methyl-L-histidine ... (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Oxilofrine
Oxilofrine is used in combination with DB11609 as an antitussive. It is currently marketed in Canada by Valeant under the tradename Cophylac.
Approved
Matched Synonyms: … Methyl synephrin ... Methyl synephrine …
3-O-Methyl-d-glucose
Experimental
Matched Synonyms: … 3-Methyl-D-glucose ... O(3)-methyl-D-glucose …
Matched Name: … 3-O-Methyl-d-glucose …
Matched Name: … 3-O-Methyl-d-glucose …
Dexamethasone
Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone. Dexamethasone was granted FDA approval on 30 October 1958....
Approved
Investigational
Vet approved
Matched Synonyms: … 16α-Methyl-9α-fluoro-1-dehydrocortisol ... 1-Dehydro-16α-methyl-9α-fluorohydrocortisone ... 16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol …
Matched Description: … dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and ... L10701] Developed in 1957, it is structurally similar to other corticosteroids like [hydrocortisone] and ... Dexamethasone reduced deaths by approximately one third in patients requiring ventilation and by one …
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Dexamethasone ... Neomycin and Polymyxin B Sulfates and Dexamethasone ... Neomycin and Polymyxin B Sulfates and Dexamethasone …
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... dexamethasone and antibiotics ... dexamethasone and antiinfectives ... dexamethasone and antiinfectives …
Matched Description: … dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and ... L10701] Developed in 1957, it is structurally similar to other corticosteroids like [hydrocortisone] and ... Dexamethasone reduced deaths by approximately one third in patients requiring ventilation and by one …
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Dexamethasone ... Neomycin and Polymyxin B Sulfates and Dexamethasone ... Neomycin and Polymyxin B Sulfates and Dexamethasone …
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... dexamethasone and antibiotics ... dexamethasone and antiinfectives ... dexamethasone and antiinfectives …
Danavorexton
Investigational
Matched Synonyms: … 1-piperidinecarboxylic acid, 3-((methylsulfonyl)amino)-2-(((cis-4-phenylcyclohexyl)oxy)methyl)-, methyl ... Methyl (2r,3s)-3-((methylsulfonyl)amino)-2-(((cis-4-phenylcyclohexyl)oxy)methyl)piperidine-1-carboxylate ... Methyl (2R,3S)-3-[(Methylsulfonyl)Amino]-2-{[(Cis-4-Phenylcyclohexyl)Oxy]Methyl}Piperidine-1-Carboxylate …
Matched Iupac: … methyl (2R,3S)-3-methanesulfonamido-2-({[(1s,4s)-4-phenylcyclohexyl]oxy}methyl)piperidine-1-carboxylate …
Matched Iupac: … methyl (2R,3S)-3-methanesulfonamido-2-({[(1s,4s)-4-phenylcyclohexyl]oxy}methyl)piperidine-1-carboxylate …
(S)-alpha-methyl-4-carboxyphenylglycine
Experimental
Matched Synonyms: … (+)-α-methyl-4-carboxyphenylglycine ... (S)-a-methyl-4-carboxyphenylglycine ... (S)-α-methyl-4-carboxyphenylglycine …
Matched Name: … (S)-alpha-methyl-4-carboxyphenylglycine …
Matched Name: … (S)-alpha-methyl-4-carboxyphenylglycine …
JTC-801 free base
An antagonist of nociceptin receptor and analgesic agent, evaluated for its use in cancer treatment.
Investigational
Matched Synonyms: … Benzamide, n-(4-amino-2-methyl-6-quinolinyl)-2-((4-ethylphenoxy)methyl)- …
Matched Iupac: … N-(4-amino-2-methylquinolin-6-yl)-2-[(4-ethylphenoxy)methyl]benzamide …
Matched Description: … An antagonist of nociceptin receptor and analgesic agent, evaluated for its use in cancer treatment. …
Matched Iupac: … N-(4-amino-2-methylquinolin-6-yl)-2-[(4-ethylphenoxy)methyl]benzamide …
Matched Description: … An antagonist of nociceptin receptor and analgesic agent, evaluated for its use in cancer treatment. …
4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol
Experimental
Matched Synonyms: … 4-CDP-2-C-methyl-D-erythritol ... 4-Diphosphocytidyl-2-C-methyl-D-erythritol …
Matched Name: … 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol …
Matched Name: … 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol …
Yohimbine
A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Approved
Investigational
Vet approved
Matched Synonyms: … Yohimbic acid methyl ester ... 17α-hydroxyyohimban-16α-carboxylic acid methyl ester ... (16α,17α)-17-hydroxyyohimban-16-carboxylic acid methyl ester …
Matched Iupac: … methyl (1S,15R,18S,19R,20S)-18-hydroxy-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa …
Matched Description: … Yohimbine has been used as a mydriatic and in the treatment of impotence. …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Iupac: … methyl (1S,15R,18S,19R,20S)-18-hydroxy-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa …
Matched Description: … Yohimbine has been used as a mydriatic and in the treatment of impotence. …
Matched Categories: … Genito Urinary System and Sex Hormones …
Displaying drugs 476 - 500 of 1826 in total