Displaying drugs 476 - 500 of 523 in total
N-Cyclohexyl-N'-(4-Iodophenyl)Urea
Experimental
Matched Name: … N-Cyclohexyl-N'-(4-Iodophenyl)Urea …
Matched Iupac: … 3-cyclohexyl-1-(4-iodophenyl)urea …
Matched Iupac: … 3-cyclohexyl-1-(4-iodophenyl)urea …
N-Cyclohexyl-N'-(Propyl)Phenyl Urea
Experimental
Matched Name: … N-Cyclohexyl-N'-(Propyl)Phenyl Urea …
Matched Iupac: … 1-cyclohexyl-3-(3-phenylpropyl)urea …
Matched Iupac: … 1-cyclohexyl-3-(3-phenylpropyl)urea …
N-(1-adamantyl)-N'-(4-guanidinobenzyl)urea
Experimental
Matched Name: … N-(1-adamantyl)-N'-(4-guanidinobenzyl)urea …
Matched Iupac: … 3-(adamantan-1-yl)-1-({4-[(diaminomethylidene)amino]phenyl}methyl)urea …
Matched Iupac: … 3-(adamantan-1-yl)-1-({4-[(diaminomethylidene)amino]phenyl}methyl)urea …
1-(4-Amidinophenyl)-3-(4-Chlorophenyl)Urea
Experimental
Matched Name: … 1-(4-Amidinophenyl)-3-(4-Chlorophenyl)Urea …
Matched Iupac: … 3-(4-carbamimidoylphenyl)-1-(4-chlorophenyl)urea …
Matched Iupac: … 3-(4-carbamimidoylphenyl)-1-(4-chlorophenyl)urea …
1-(2-Amidinophenyl)-3-(Phenoxyphenyl)Urea
Experimental
Matched Name: … 1-(2-Amidinophenyl)-3-(Phenoxyphenyl)Urea …
Matched Iupac: … 3-(4-carbamimidoylphenyl)-1-(4-phenoxyphenyl)urea …
Matched Iupac: … 3-(4-carbamimidoylphenyl)-1-(4-phenoxyphenyl)urea …
ONO-7579
Investigational
Matched Synonyms: … (2-amino-5-chloropyridin-3-yl)phenoxy]pyrimidin-5-yl]-3-[2-methylsulfonyl-5-(trifluoromethyl)phenyl]urea …
Ilorasertib
Ilorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others.
Investigational
Matched Synonyms: … -(4-amino-7-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)thieno[3,2-c]pyridin-3-yl)phenyl)-3-(3-fluorophenyl)urea ... {4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridine-3-yl}phenyl)-3-(3-fluorophenyl)urea ... Urea, N-(4-(4-amino-7-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)thieno(3,2-c)pyridin-3-yl)phenyl)-N'-(3-fluorophenyl …
Matched Iupac: … -{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridin-3-yl}phenyl)-3-(3-fluorophenyl)urea …
Matched Description: … studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and …
Matched Iupac: … -{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridin-3-yl}phenyl)-3-(3-fluorophenyl)urea …
Matched Description: … studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and …
Ceclazepide
Investigational
Matched Synonyms: … oxo-butyl)-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1h-benzo(e)(1,4)diazepin-3-yl)-3-(3-methylamino-phenyl)-urea ... Urea, n-((3r)-1-(4-(acetyloxy)-3,3-dimethyl-2-oxobutyl)-2,3-dihydro-2-oxo-5-(2-pyridinyl)-1h-1,4-benzodiazepin …
Lufenuron
Lufenuron is used in veterinary for the control of flea.
Experimental
Vet approved
Matched Synonyms: … 1-(2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)-3-(2,6-difluorobenzoyl)urea …
Matched Iupac: … 1-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-3-(2,6-difluorobenzoyl)urea …
Matched Iupac: … 1-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-3-(2,6-difluorobenzoyl)urea …
N-acetyl-N'-beta-D-glucopyranosyl urea
Experimental
Matched Name: … N-acetyl-N'-beta-D-glucopyranosyl urea …
Matched Iupac: … 3-acetyl-1-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]urea …
Matched Iupac: … 3-acetyl-1-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]urea …
Chlorpropamide
Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class...
Approved
Investigational
Matched Synonyms: … 1-propyl-3-(p-chlorobenzenesulfonyl)urea ... n-propyl-N'-(p-chlorobenzenesulfonyl)urea …
Matched Description: … increase the number and sensitivity of insulin receptors. ... Renal and hepatic dysfunction may increase the risk of hypoglycemia. ... Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Description: … increase the number and sensitivity of insulin receptors. ... Renal and hepatic dysfunction may increase the risk of hypoglycemia. ... Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
1-(3-fluoro-4-(7-(5-methyl-1H-imidazol-2-yl)-1-oxo-2,3-dihydro-1H-isoindo-1-4-yl)-phenyl)-3-(3-trifluoromethyl-phenyl)-urea
Investigational
Matched Synonyms: … Urea, n-(4-(2,3-dihydro-7-(5-methyl-1h-imidazol-2-yl)-1-oxo-1h-isoindol-4-yl)-3-fluorophenyl)-n'-(3-( …
Matched Name: … -methyl-1H-imidazol-2-yl)-1-oxo-2,3-dihydro-1H-isoindo-1-4-yl)-phenyl)-3-(3-trifluoromethyl-phenyl)-urea …
Matched Iupac: … (4-methyl-1H-imidazol-2-yl)-1-oxo-2,3-dihydro-1H-isoindol-4-yl]phenyl}-1-[3-(trifluoromethyl)phenyl]urea …
Matched Name: … -methyl-1H-imidazol-2-yl)-1-oxo-2,3-dihydro-1H-isoindo-1-4-yl)-phenyl)-3-(3-trifluoromethyl-phenyl)-urea …
Matched Iupac: … (4-methyl-1H-imidazol-2-yl)-1-oxo-2,3-dihydro-1H-isoindol-4-yl]phenyl}-1-[3-(trifluoromethyl)phenyl]urea …
Torasemide
Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.
Approved
Matched Synonyms: … 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea …
Matched Iupac: … 1-({4-[(3-methylphenyl)amino]pyridin-3-yl}sulfonyl)-3-(propan-2-yl)urea …
Matched Iupac: … 1-({4-[(3-methylphenyl)amino]pyridin-3-yl}sulfonyl)-3-(propan-2-yl)urea …
Cefuroxime
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Matched Description: … It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose …
Fobrepodacin
Investigational
Matched Synonyms: … -(1-methyl-1-(phosphonooxy)ethyl)-5-pyrimidinyl)-7-((2r)-tetrahydro-2-furanyl)-1h-benzimidazol-2-yl)urea ... Urea, n-ethyl-n'-(6-fluoro-5-(2-(1-methyl-1-(phosphonooxy)ethyl)-5-pyrimidinyl)-7-((2r)-tetrahydro-2- …
Glipizide
Glipizide is an oral hypoglycemic agent in the second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 diabetes mellitus. It was first introduced in 1984 and is available in various countries including Canada and the U.S. According to the 2018 Clinical Practice...
Approved
Investigational
Matched Synonyms: … 1-cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)urea …
Matched Description: … It was first introduced in 1984 [A179491] and is available in various countries including Canada and ... onset of action with the shortest half-life and duration of action, reducing the risk for long-lasting ... [A179485] Glipizide was first approved by the FDA in 1994 and is available in extended-release tablets …
Matched Mixtures name: … Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Description: … It was first introduced in 1984 [A179491] and is available in various countries including Canada and ... onset of action with the shortest half-life and duration of action, reducing the risk for long-lasting ... [A179485] Glipizide was first approved by the FDA in 1994 and is available in extended-release tablets …
Matched Mixtures name: … Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism …
Quizartinib
Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug developed specifically targeting FLT3, as other agents with FLT3 inhibition activities were investigated with other targets in mind. Additionally, quizartinib also demonstrates inhibitory activity toward FLT3 with internal tandem duplication (ITD), although...
Approved
Investigational
Matched Synonyms: … Dimethylethyl)isoxazol-3-yl)-N'-(4-(7-(2-(morpholin-4-yl)ethoxy)imidazo(2,1-b)benzothiazol-2-yl)phenyl)urea …
Matched Iupac: … morpholin-4-yl)ethoxy]-7-thia-2,5-diazatricyclo[6.4.0.0²,⁶]dodeca-1(8),3,5,9,11-pentaen-4-yl}phenyl)urea …
Matched Description: … Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug ... thus poorer overall survival and higher risk of relapse. ... L47426] FLT3-ITD mutation is present in 75% of FLT3-mutated AML, leading to constitutively active FLT3 and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … morpholin-4-yl)ethoxy]-7-thia-2,5-diazatricyclo[6.4.0.0²,⁶]dodeca-1(8),3,5,9,11-pentaen-4-yl}phenyl)urea …
Matched Description: … Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug ... thus poorer overall survival and higher risk of relapse. ... L47426] FLT3-ITD mutation is present in 75% of FLT3-mutated AML, leading to constitutively active FLT3 and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Ceftriaxone
Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone...
Approved
Matched Description: … meninges[A215582], eyes[A215647], and inner ear[A215627]. ... its long half-life which allows for the convenience of daily or twice-daily dosing. ... [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the …
Matched Products: … Ceftriaxone and Dextrose …
Matched Products: … Ceftriaxone and Dextrose …
Tolazamide
A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Approved
Investigational
Matched Synonyms: … 1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea …
Matched Iupac: … 1-(azepan-1-yl)-3-(4-methylbenzenesulfonyl)urea …
Matched Description: … A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Iupac: … 1-(azepan-1-yl)-3-(4-methylbenzenesulfonyl)urea …
Matched Description: … A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
N-(2-CHLORO-4-FLUOROBENZOYL)-N'-(5-HYDROXY-2-METHOXYPHENYL)UREA
Experimental
Matched Name: … N-(2-CHLORO-4-FLUOROBENZOYL)-N'-(5-HYDROXY-2-METHOXYPHENYL)UREA …
Matched Iupac: … 1-(2-chloro-4-fluorobenzoyl)-3-(5-hydroxy-2-methoxyphenyl)urea …
Matched Iupac: … 1-(2-chloro-4-fluorobenzoyl)-3-(5-hydroxy-2-methoxyphenyl)urea …
1-[4-(PYRIDIN-4-YLOXY)PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA
Experimental
Matched Name: … 1-[4-(PYRIDIN-4-YLOXY)PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA …
Matched Iupac: … 1-[4-(pyridin-4-yloxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea …
Matched Iupac: … 1-[4-(pyridin-4-yloxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea …
Amlodipine
Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched Description: … Amlodipine is commonly used in the treatment of high blood pressure and angina. ... dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and ... Amlodipine has antioxidant properties and an ability to enhance the production of nitric oxide (NO), …
Matched Mixtures name: … Amlodipine Besylate and Benazepril Hydrochloride ... AMLODIPINE and VALSARTAN ... Amlodipine and Valsartan …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... nebivolol and amlodipine ... aliskiren and amlodipine ... benazepril and amlodipine ... losartan and amlodipine …
Matched Products: … AMLODIGAMMA TOP 5MG ... AMLODIGAMMA TOP 10MG …
Matched Mixtures name: … Amlodipine Besylate and Benazepril Hydrochloride ... AMLODIPINE and VALSARTAN ... Amlodipine and Valsartan …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... nebivolol and amlodipine ... aliskiren and amlodipine ... benazepril and amlodipine ... losartan and amlodipine …
Matched Products: … AMLODIGAMMA TOP 5MG ... AMLODIGAMMA TOP 10MG …
CT-179
Investigational
Matched Synonyms: … Urea, n-(3,4-dichlorophenyl)-n'-(4-((3-(dimethylamino)propyl)amino)-6-methyl-2-pyrimidinyl)- …
Matched Iupac: … 1-(3,4-dichlorophenyl)-3-(4-{[3-(dimethylamino)propyl]amino}-6-methylpyrimidin-2-yl)urea …
Matched Iupac: … 1-(3,4-dichlorophenyl)-3-(4-{[3-(dimethylamino)propyl]amino}-6-methylpyrimidin-2-yl)urea …
Sorafenib
Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also...
Approved
Investigational
Matched Synonyms: … N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea …
Matched Description: … Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. ... in tumour cell proliferation and tumour angiogenesis. ... It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. ... in tumour cell proliferation and tumour angiogenesis. ... It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
1-(5-CHLORO-2,4-DIMETHOXYPHENYL)-3-(5-CYANOPYRAZIN-2-YL)UREA
Experimental
Matched Name: … 1-(5-CHLORO-2,4-DIMETHOXYPHENYL)-3-(5-CYANOPYRAZIN-2-YL)UREA …
Matched Iupac: … 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-cyanopyrazin-2-yl)urea …
Matched Iupac: … 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-cyanopyrazin-2-yl)urea …
Displaying drugs 476 - 500 of 523 in total