Displaying drugs 476 - 500 of 538 in total
Triclocarban
Triclocarban, with the chemical formula C13H9Cl3N2O is an antibacterial agent that is particularly effective against Gram-positive bacteria such as Staphylococcus aureus. It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products. In 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer...
Approved
Matched Synonyms: … 1-(3',4'-dichlorophenyl)-3-(4'-chlorophenyl)urea ... N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl)urea …
Matched Iupac: … 3-(4-chlorophenyl)-1-(3,4-dichlorophenyl)urea …
Matched Description: … It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products …
Matched Iupac: … 3-(4-chlorophenyl)-1-(3,4-dichlorophenyl)urea …
Matched Description: … It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products …
Gliclazide
Gliclazide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It has been classified differently according to its drug properties in which based on its chemical structure, gliclazide is considered a first-generation sulfonylurea due to the structural presence of a sulfonamide group able to release...
Approved
Matched Synonyms: … 1-(3-azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea ... 1-(hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea …
Matched Iupac: … 3-[(3aR,6aS)-octahydrocyclopenta[c]pyrrol-2-yl]-1-(4-methylbenzenesulfonyl)urea …
Matched Description: … increase the number and sensitivity of insulin receptors. ... Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. ... The risk of hypoglycemia is increased in elderly, debilitated and malnourished individuals. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Iupac: … 3-[(3aR,6aS)-octahydrocyclopenta[c]pyrrol-2-yl]-1-(4-methylbenzenesulfonyl)urea …
Matched Description: … increase the number and sensitivity of insulin receptors. ... Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. ... The risk of hypoglycemia is increased in elderly, debilitated and malnourished individuals. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Nitroglycerin
Nitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced relief...
Approved
Investigational
Matched Description: … [A180166,A180172] Its use as a treatment for angina dates back to 1879 and is still used to treat and ... [A249970] Nitroglycerin causes vasodilation in both arteries and veins. ... Nitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent …
Matched Categories: … Nitrates and Nitrites ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … TOP-NITRO …
Matched Categories: … Nitrates and Nitrites ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … TOP-NITRO …
(4-(trifluoromethoxy)phenyl)urea
Experimental
Matched Name: … (4-(trifluoromethoxy)phenyl)urea …
Matched Iupac: … [4-(trifluoromethoxy)phenyl]urea …
Matched Iupac: … [4-(trifluoromethoxy)phenyl]urea …
Zinc sulfate
Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol". It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Approved
Investigational
Matched Description: … Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol …
Matched Mixtures name: … Prenatal Vitamin and Mineral Supplement ... Multiple Vitamins and Minerals ... Calcium and Magnesium W Zinc Tab …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Skin and Mucous Membrane Agents ... Blood Substitutes and Perfusion Solutions ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Anu-aide - Ont Top 0.5% …
Matched Mixtures name: … Prenatal Vitamin and Mineral Supplement ... Multiple Vitamins and Minerals ... Calcium and Magnesium W Zinc Tab …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Skin and Mucous Membrane Agents ... Blood Substitutes and Perfusion Solutions ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Anu-aide - Ont Top 0.5% …
Linifanib
Linifanib (ABT-869) is a small molecule vascular endothelial growth factor (VEGF) receptor-based kinase inhibitor that is designed to suppress tumor growth by preventing the formation of new blood vessels that supply the tumor with oxygen and nutrients and by inhibiting key angiogenic signaling pathways. Linifanib is intended for the treatment...
Investigational
Matched Synonyms: … 1-(4-(3-AMINO-1H-INDAZOL-4-YL)PHENYL)-3-(2-FLUORO-5-METHYLPHENYL)UREA ... N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N1-(2-fluoro-5-methylphenyl) urea ... UREA, N-(4-(3-AMINO-1H-INDAZOL-4-YL)PHENYL)-N'-(2-FLUORO-5-METHYLPHENYL)- …
Matched Iupac: … 3-[4-(3-amino-1H-indazol-4-yl)phenyl]-1-(2-fluoro-5-methylphenyl)urea …
Matched Description: … nutrients and by inhibiting key angiogenic signaling pathways. ... Linifanib is intended for the treatment of hematologic malignancies and the solid tumors. ... suppress tumor growth by preventing the formation of new blood vessels that supply the tumor with oxygen and …
Matched Iupac: … 3-[4-(3-amino-1H-indazol-4-yl)phenyl]-1-(2-fluoro-5-methylphenyl)urea …
Matched Description: … nutrients and by inhibiting key angiogenic signaling pathways. ... Linifanib is intended for the treatment of hematologic malignancies and the solid tumors. ... suppress tumor growth by preventing the formation of new blood vessels that supply the tumor with oxygen and …
Eucalyptus oil
Eucalyptus oil is a distilled oil derived from the leaves of the tree Eucalyptus. It is shown to be effective in reducing pain, swelling, and inflammation via its modulatory effect on the immune response. It is also shown to exhibit antibacterial activity against some bacterial species and cough suppressant actions....
Approved
Matched Synonyms: … Eucalyptus globulus leaf/twig oil …
Matched Description: … membranes, joint pain, genital herpes, and nasal stuffiness. ... It is shown to be effective in reducing pain, swelling, and inflammation via its modulatory effect on ... It is also shown to exhibit antibacterial activity against some bacterial species and cough suppressant …
Matched Mixtures name: … SAM SEEH BRAND LINIMENT ... Medicated Chest Rub - Ont Top ... Muscle and Joint Heat Cream …
Matched Categories: … Other Cold and Cough Preparations …
Matched Description: … membranes, joint pain, genital herpes, and nasal stuffiness. ... It is shown to be effective in reducing pain, swelling, and inflammation via its modulatory effect on ... It is also shown to exhibit antibacterial activity against some bacterial species and cough suppressant …
Matched Mixtures name: … SAM SEEH BRAND LINIMENT ... Medicated Chest Rub - Ont Top ... Muscle and Joint Heat Cream …
Matched Categories: … Other Cold and Cough Preparations …
Magnesium hydroxide
Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form.
Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used commercially...
Approved
Investigational
Matched Description: … Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used …
Matched Mixtures name: … Antacid and Antigas ... Mylanta Coat and Cool ... Antacid and Gasrelief …
Matched Categories: … Antacids and Adsorbents ... Alimentary Tract and Metabolism ... Basic Ointments and Protectants ... Aluminum and magnesium containing antacids ... Emollients Demulcents and Protectants …
Matched Products: … Dermagran II Ointment-ont Top 0.25% …
Matched Mixtures name: … Antacid and Antigas ... Mylanta Coat and Cool ... Antacid and Gasrelief …
Matched Categories: … Antacids and Adsorbents ... Alimentary Tract and Metabolism ... Basic Ointments and Protectants ... Aluminum and magnesium containing antacids ... Emollients Demulcents and Protectants …
Matched Products: … Dermagran II Ointment-ont Top 0.25% …
Tolbutamide
Tolbutamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin...
Approved
Investigational
Matched Synonyms: … 1-Butyl-3-(p-tolylsulfonyl)urea ... 1-Butyl-3-(p-methylphenylsulfonyl)urea ... N-Butyl-N'-(p-tolylsulfonyl)urea …
Matched Iupac: … 3-butyl-1-(4-methylbenzenesulfonyl)urea …
Matched Description: … It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea ... Tolbutamide and its metabolites are excreted in urine (75-85%) and feces. ... increase the number and sensitivity of insulin receptors. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Iupac: … 3-butyl-1-(4-methylbenzenesulfonyl)urea …
Matched Description: … It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea ... Tolbutamide and its metabolites are excreted in urine (75-85%) and feces. ... increase the number and sensitivity of insulin receptors. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Imidocarb
Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia and other parasites.
Vet approved
Matched Synonyms: … 1,3-bis(3-(2-imidazolin-2-yl)phenyl)urea ... N,N'-bis(3-(4,5-dihydro-1H-imidazol-2-yl)phenyl)urea …
Matched Iupac: … 1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea …
Matched Description: … of infection with Babesia and other parasites. ... Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment …
Matched Iupac: … 1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea …
Matched Description: … of infection with Babesia and other parasites. ... Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment …
Chlormerodrin
Chlormerodrin is a mercurial compound with toxic side effects that was previously used as a diuretic. The radiolabeled form has been used as a diagnostic and research tool. It is no longer used and has been replaced with new classes of diuretic drugs.
Approved
Withdrawn
Matched Synonyms: … 1-[3-(chloromercuri)-2-methoxypropyl]urea …
Matched Iupac: … [3-(chloromercurio)-2-methoxypropyl]urea …
Matched Description: … The radiolabeled form has been used as a diagnostic and research tool. ... It is no longer used and has been replaced with new classes of diuretic drugs. …
Matched Iupac: … [3-(chloromercurio)-2-methoxypropyl]urea …
Matched Description: … The radiolabeled form has been used as a diagnostic and research tool. ... It is no longer used and has been replaced with new classes of diuretic drugs. …
AT9283
AT9283 is an aurora Kinase inhibitor developed by Astex Therapeutics for the treatment of cancer. It was discovered and developed internally using Astex’s fragment-based drug discovery platform, Pyramid.
Investigational
Matched Synonyms: … 1-Cyclopropyl-3-[3-(5-morpholin-4-ylmethyl-1H-benzoimidazol-2-yl)-1H-pyrazol-4-yl]-urea …
Matched Description: … It was discovered and developed internally using Astex’s fragment-based drug discovery platform, Pyramid …
Matched Description: … It was discovered and developed internally using Astex’s fragment-based drug discovery platform, Pyramid …
SNS-314
SNS-314 is a potent and selective inhibitor of Aurora kinases A, B, and C. Proliferating cells treated with SNS-314 bypass the mitotic spindle checkpoint and fail to undergo cytokinesis, leading to multiple rounds of endoreduplication and eventually cell death. SNS-314 inhibits tumor growth in a variety of preclinical models, and...
Investigational
Matched Synonyms: … 1-(3-chlorophenyl)-3-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}urea …
Matched Iupac: … 1-(3-chlorophenyl)-3-{5-[2-({thieno[3,2-d]pyrimidin-4-yl}amino)ethyl]-1,3-thiazol-2-yl}urea …
Matched Description: … SNS-314 is a potent and selective inhibitor of Aurora kinases A, B, and C. ... , leading to multiple rounds of endoreduplication and eventually cell death. ... Proliferating cells treated with SNS-314 bypass the mitotic spindle checkpoint and fail to undergo cytokinesis …
Matched Iupac: … 1-(3-chlorophenyl)-3-{5-[2-({thieno[3,2-d]pyrimidin-4-yl}amino)ethyl]-1,3-thiazol-2-yl}urea …
Matched Description: … SNS-314 is a potent and selective inhibitor of Aurora kinases A, B, and C. ... , leading to multiple rounds of endoreduplication and eventually cell death. ... Proliferating cells treated with SNS-314 bypass the mitotic spindle checkpoint and fail to undergo cytokinesis …
NS-3728
NS3728 is an orally active chloride channel blocker for the treatment of cancer.
Investigational
Matched Synonyms: … N-[4-bromo-2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-N'-[3,5-bis(trifluoromethyl)phenyl]urea …
Matched Iupac: … 1-[3,5-bis(trifluoromethyl)phenyl]-3-[5-bromo-2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]urea …
Matched Iupac: … 1-[3,5-bis(trifluoromethyl)phenyl]-3-[5-bromo-2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]urea …
LP-184
Investigational
Matched Synonyms: … N-HYDROXY-N-(METHYLACYLFULVENE)UREA ... HYDROXY-1-((6'-HYDROXY-2',4',6'-TRIMETHYL-7'-OXO-6',7'-DIHYDROSPIRO(CYCLOPROPANE-1,5'-INDEN)-3'-YL)METHYL)UREA ... UREA, N-(((6'R)-6',7'-DIHYDRO-6'-HYDROXY-2',4',6'-TRIMETHYL-7'-OXOSPIRO(CYCLOPROPANE-1,5'-(5H)INDEN)- …
Matched Iupac: … (6'R)-6'-hydroxy-2',4',6'-trimethyl-7'-oxo-6',7'-dihydrospiro[cyclopropane-1,5'-inden]-3'-yl]methyl}urea …
Matched Iupac: … (6'R)-6'-hydroxy-2',4',6'-trimethyl-7'-oxo-6',7'-dihydrospiro[cyclopropane-1,5'-inden]-3'-yl]methyl}urea …
N-Cyclohexyl-N'-(4-Iodophenyl)Urea
Experimental
Matched Name: … N-Cyclohexyl-N'-(4-Iodophenyl)Urea …
Matched Iupac: … 3-cyclohexyl-1-(4-iodophenyl)urea …
Matched Iupac: … 3-cyclohexyl-1-(4-iodophenyl)urea …
N-Cyclohexyl-N'-(Propyl)Phenyl Urea
Experimental
Matched Name: … N-Cyclohexyl-N'-(Propyl)Phenyl Urea …
Matched Iupac: … 1-cyclohexyl-3-(3-phenylpropyl)urea …
Matched Iupac: … 1-cyclohexyl-3-(3-phenylpropyl)urea …
ONO-7579
Investigational
Matched Synonyms: … (2-amino-5-chloropyridin-3-yl)phenoxy]pyrimidin-5-yl]-3-[2-methylsulfonyl-5-(trifluoromethyl)phenyl]urea …
N-(1-adamantyl)-N'-(4-guanidinobenzyl)urea
Experimental
Matched Name: … N-(1-adamantyl)-N'-(4-guanidinobenzyl)urea …
Matched Iupac: … 3-(adamantan-1-yl)-1-({4-[(diaminomethylidene)amino]phenyl}methyl)urea …
Matched Iupac: … 3-(adamantan-1-yl)-1-({4-[(diaminomethylidene)amino]phenyl}methyl)urea …
1-(4-Amidinophenyl)-3-(4-Chlorophenyl)Urea
Experimental
Matched Name: … 1-(4-Amidinophenyl)-3-(4-Chlorophenyl)Urea …
Matched Iupac: … 3-(4-carbamimidoylphenyl)-1-(4-chlorophenyl)urea …
Matched Iupac: … 3-(4-carbamimidoylphenyl)-1-(4-chlorophenyl)urea …
1-(2-Amidinophenyl)-3-(Phenoxyphenyl)Urea
Experimental
Matched Name: … 1-(2-Amidinophenyl)-3-(Phenoxyphenyl)Urea …
Matched Iupac: … 3-(4-carbamimidoylphenyl)-1-(4-phenoxyphenyl)urea …
Matched Iupac: … 3-(4-carbamimidoylphenyl)-1-(4-phenoxyphenyl)urea …
Ilorasertib
Ilorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others.
Investigational
Matched Synonyms: … -(4-amino-7-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)thieno[3,2-c]pyridin-3-yl)phenyl)-3-(3-fluorophenyl)urea ... {4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridine-3-yl}phenyl)-3-(3-fluorophenyl)urea ... Urea, N-(4-(4-amino-7-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)thieno(3,2-c)pyridin-3-yl)phenyl)-N'-(3-fluorophenyl …
Matched Iupac: … -{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridin-3-yl}phenyl)-3-(3-fluorophenyl)urea …
Matched Description: … studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and …
Matched Iupac: … -{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridin-3-yl}phenyl)-3-(3-fluorophenyl)urea …
Matched Description: … studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and …
Ceclazepide
Investigational
Matched Synonyms: … oxo-butyl)-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1h-benzo(e)(1,4)diazepin-3-yl)-3-(3-methylamino-phenyl)-urea ... Urea, n-((3r)-1-(4-(acetyloxy)-3,3-dimethyl-2-oxobutyl)-2,3-dihydro-2-oxo-5-(2-pyridinyl)-1h-1,4-benzodiazepin …
Lufenuron
Lufenuron is used in veterinary for the control of flea.
Experimental
Vet approved
Matched Synonyms: … 1-(2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)-3-(2,6-difluorobenzoyl)urea …
Matched Iupac: … 1-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-3-(2,6-difluorobenzoyl)urea …
Matched Iupac: … 1-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-3-(2,6-difluorobenzoyl)urea …
N-acetyl-N'-beta-D-glucopyranosyl urea
Experimental
Matched Name: … N-acetyl-N'-beta-D-glucopyranosyl urea …
Matched Iupac: … 3-acetyl-1-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]urea …
Matched Iupac: … 3-acetyl-1-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]urea …
Displaying drugs 476 - 500 of 538 in total