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Displaying drugs 476 - 500 of 725 in total

Benzethonium

Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1-0.2 %, which are safe and effective concentrations for the compound specified by the U.S. Food and Drug Administration (FDA)....
Approved
Matched Description: … Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1 ... It is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments. ... Food and Drug Administration (FDA). …
Matched Mixtures name: … Oti-sol ... Gold Bond Pain and Itch ... Benzocaine and Benzethonium …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … LYSOL Healthy Touch Cleansing Green Tea and Ginger ... Foaming Instant Hand Sanitizer with Aloe and Vitamin E ... Loesch Original Kleer-Plex Antimicrobial Face and Body Wash …

Minoxidil

A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Approved
Investigational
Matched Description: … potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and …
Matched Categories: … Skin and Mucous Membrane Agents ... Arteriolar Smooth Muscle, Agents Acting On …
Matched Products: … Hair essential oil ... Glemme Beard Growth Oil ... Up and Up Minoxidil …

Metolazone

A quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
Approved
Matched Synonyms: … 7-Chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamide ... 2-Methyl-3-o-tolyl-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone ... 7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide …
Matched Iupac: … 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide …
Matched Description: … It also tends to lower blood pressure and increase potassium loss. …
Matched Categories: … combinations of sulfonamides ... Genito Urinary System and Sex Hormones ... metolazone and potassium-sparing agents ... Gynecological Antiinfectives and Antiseptics ... Low-Ceiling Diuretics and Potassium-Sparing Agents …

Pyrethrum extract

Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. Pyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities. Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species....
Approved
Matched Synonyms: … Pyrethrins and pyrethroids ... Pyrethrins component of rid mousse …
Matched Description: … The active compound is absorbed by the lice and destroys them by acting on their nervous systems but ... Pyrethrum extract is also used used to treat head, body, and pubic lice infections. ... is thought to exert minimal effect on humans. …
Matched Mixtures name: … Care One Lice Killing ... Medi and Lice Lice Killing ... Lice-Nil Lice and Eggs Killer …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Acapatamab

Acapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Investigational
Matched Synonyms: … scfv-scfv-scfc, anti-(homo sapiens folh1 (folate hydrolase, prostate specific membrane antigen, psma)) and …
Matched Description: … Acapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for …

Dapiprazole

Dapiprazole (U.S. trade name Rev-Eyes) is an alpha blocker. It is found in ophthalmic solutions used to reverse mydriasis after an eye examination.
Approved
Matched Synonyms: … 5,6,7,8-Tetrahydro-3-(2-(4-(o-tolyl)-1-piperazinyl)ethyl)-s-triazolo(4,3-a)pyridine …
Matched Categories: … Antiglaucoma Preparations and Miotics …

Lorigerlimab

Lorigerlimab is under investigation in clinical trial NCT05848011 (A Study of Lorigerlimab With Docetaxel or Docetaxel Alone in Participants With Metastatic Castration-resistant Prostate Cancer).
Investigational
Matched Synonyms: … ANTI-(HOMO SAPIENS CTLA4 (CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, CD152)), CHIMERIC, HOMO SAPIENS AND ... MMUNOGLOBULIN G4 SCFV-H-CH2-CH3_SCFV, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD1, PD-1, CD279)) AND …
Matched Description: … or Docetaxel Alone in Participants With Metastatic Castration-resistant Prostate Cancer). ... Lorigerlimab is under investigation in clinical trial NCT05848011 (A Study of Lorigerlimab With Docetaxel …

Thimerosal

Thiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent. Developed in 1927, thimerosal has been and is still being used as a preservative in some cosmetics, topical pharmaceuticals, and biological drug products, which includes...
Approved
Matched Synonyms: … [(o-carboxyphenyl)thio]ethylmercury sodium salt ... o-(ethylmercurithio)benzoic acid sodium salt …
Matched Description: … This compound is a well-established and widely used antiseptic and antifungal agent. ... pharmaceuticals, and biological drug products, which includes vaccines. ... There has been significant concern regarding its safety and toxicity in the last several decades. …
Matched Categories: … Antiseptics and Disinfectants ... Compounds used in a research, industrial, or household setting …

Methylcellulose

Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3,...
Approved
Matched Description: … and emulsifier for foodstuffs and cosmetics. ... Like cellulose, it is not digestible, not toxic, and not allergenic ... The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number …
Matched Categories: … Alimentary Tract and Metabolism ... Compounds used in a research, industrial, or household setting …
Matched Products: … Foster and Thrive Fiber Laxative 188 …

beta-D-fructofuranose 1,6-bisphosphate

Experimental
Matched Synonyms: … 1,6-di-O-phosphono-β-D-fructofuranose …

Teniposide

Teniposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent cells from entering into the mitotic...
Approved
Matched Synonyms: … 4'-demethylepipodophyllotoxin 9-(4,6-O-(R)-2-thenylidene-beta-D-glucopyranoside) …
Matched Iupac: … -{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-(thiophen-2-yl)-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy ... hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one …
Matched Description: … Teniposide acts primarily in the G2 and S phases of the cycle. ... Accumulated breaks in DNA prevent cells from entering into the mitotic phase of the cell cycle, and lead ... Teniposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Famotidine

Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric acid secretion. It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. Compared to other H2 receptor antagonists, famotidine displays high selectivity towards...
Approved
Matched Description: … [A189462] Famotidine is used in various over-the-counter and off-label uses. ... [ranitidine] on a weight basis. ... [L11166] While oral formulations of famotidine are more commonly used, the intravenous solution of the …
Matched Mixtures name: … Care One Acid Reducer and Antacid Dual Action ... Care One Acid Reducer plus Antacid Dual Action ... Ibuprofen and famotidine …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Care One Acid Reducer Original Strength ... Up and Up Famotidine ... Berkley and Jensen Famotidine …

Titanium dioxide

Titanium dioxide, also known as titanium(IV) oxide or titania, is the naturally occurring oxide of titanium. It is used as a pigment under the names titanium white, Pigment White 6 (PW6), or CI 77891. It is typically extracted from ilmenite, rutile and anatase.
Approved
Matched Description: … It is typically extracted from ilmenite, rutile and anatase. ... Titanium dioxide, also known as titanium(IV) oxide or titania, is the naturally occurring oxide of titanium ... It is used as a pigment under the names titanium white, Pigment White 6 (PW6), or CI 77891. …
Matched Mixtures name: … Avobenzone, Octinoxate, Titanium Dioxide ... Avobenzone, Octinoxate, Titanium Dioxide ... Avobenzone, Octinoxate, Titanium Dioxide …
Matched Categories: … Astringents and Deodorants ... Compounds used in a research, industrial, or household setting …
Matched Products: … Quick and Clean Oil Free Sun Spf35 Pa ... Oil Of Olay Complete Radiance Foundation ... (oil-free)p2 …

5-O-phosphono-alpha-D-ribofuranosyl diphosphate

The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
Approved
Experimental
Investigational
Matched Synonyms: … 5-O-phosphono-α-D-ribofuranosyl diphosphate …
Matched Name: … 5-O-phosphono-alpha-D-ribofuranosyl diphosphate …
Matched Iupac: … [({[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]oxy}(hydroxy)phosphoryl)oxy]phosphonic …
Matched Description: … The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides …

4-O-methyl-beta-D-glucuronic acid

Experimental
Matched Name: … 4-O-methyl-beta-D-glucuronic acid …

2,3-Di-O-Sulfo-Alpha-D-Glucopyranose

Experimental
Matched Name: … 2,3-Di-O-Sulfo-Alpha-D-Glucopyranose …

Beta-1,2,3,4,6-Penta-O-Galloyl-D-Glucopyranose

Experimental
Matched Name: … Beta-1,2,3,4,6-Penta-O-Galloyl-D-Glucopyranose …

[4,6-O-(1-CARBOXYETHYLIDENE)-BETA-D-MANNOSE]

Experimental
Matched Name: … [4,6-O-(1-CARBOXYETHYLIDENE)-BETA-D-MANNOSE] …

Garcinia gummi-gutta fruit

Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Garcinia Cambogia (Constituent of Garcinia Cambogia and Garcinia Indica) …
Matched Description: … Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. …

DCLL-9718S

DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy).
Investigational
Matched Synonyms: … antibody and DNA alkylating cross-linking agent pyrrolo [2,1-c][1,4] benzodiazepine dimer ... THIOMAB antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal …
Matched Description: … With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine ... DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Bismuth subsalicylate

Bismuth subsalicylate is an antacid and anti-diarrheal agent. Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of salicylic acid linked to trivalent bismuth cation. Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. Bismuth subsalicylate has been around for over 100 years: it...
Approved
Vet approved
Matched Synonyms: … 2-Hydroxy-benzo[1,3,2]dioxabismin-4-one …
Matched Iupac: … 2-hydroxy-2H,4H-benzo[d]1,3-dioxa-2-bismacyclohexan-4-one …
Matched Description: … treatment of patients with _H. pylori_ infection and duodenal ulcer disease. ... Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. ... ], and [tetracycline]), which is a treatment regimen indicated for the eradication of _H. pylori_ for …
Matched Mixtures name: … Pepto-Bismol and Pepto-Bismol To Go ... Pepto-Bismol and Pepto-Bismol To Go …
Matched Categories: … Antacids and Adsorbents …
Matched Products: … Up and Up Stomach Relief ... Up and Up Digestive Relief ... Foster and Thrive Stomach Relief …

Dimethyl sulfoxide

A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during cryopreservation. Dimethyl sulfoxide shows a range of pharmacological activity including...
Approved
Vet approved
Matched Synonyms: … S(O)Me2 …
Matched Description: … Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation ... of pharmaceuticals. ... Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Genito Urinary System and Sex Hormones ... Topical Products for Joint and Muscular Pain …

Tepilamide fumarate

Investigational
Matched Synonyms: … 2-(diethylamino)-2-oxoethyl and methyl (2e)-but-2-enedioate …

Diphenhydramine

Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269,...
Approved
Investigational
Matched Synonyms: … O-benzhydryldimethylaminoethanol …
Matched Description: … While its use in allergy therapy can sometimes fall out of favor due to its sedative effect, diphenhydramine ... seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. ... has been repurposed for use within many non-prescription over-the-counter sleep aids and cough-and-cold …
Matched Mixtures name: … Complete One Cold and Flu PE Night ... Care One Flu and Severe Cold and Cough Nighttime ... Care One Pain Relief and Pain Relief PM …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome ... Hypnotics and Sedatives ... naproxen and diphenhydramine ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … ORA ALERGI ... NERVO OPT N ... On The GO-Dose …

Bisacodyl

Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Description: … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-( ... [A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as …
Matched Mixtures name: … HalfLytely and Bisacodyl ... HalfLytely and Bisacodyl ... GaviLyte-H and Bisacodyl …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up womens laxative ... Up and Up Gentle Laxative ... Foster and Thrive Gentle Laxative …
Displaying drugs 476 - 500 of 725 in total