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Displaying drugs 476 - 500 of 15051 in total

Bemotrizinol

Bemotrizinol, or bis-ethylhexyloxyphenol methoxyphenyl triazine, is an organic UV filter found in over-the-counter sunscreen products. It primarily absorbs UV-A rays. Compared to older broad-spectrum chemical agents, bemotrizinol is more more fat soluble (oil soluble in cosmetic oils) to aid in efficacy and broad-spectrum activity . It is claimed to be...
Approved
Matched Description: … Bemotrizinol is commonly marketed as Tinosorb S and Escalol S. ... It is claimed to be photostable, which increases its onset of action and its efficiency in providing ... chemical agents, bemotrizinol is more more fat soluble (oil soluble in cosmetic oils) to aid in efficacy and …
Matched Mixtures name: … Kiehls Activated Sun Protector Sunscreen SPF 50 For Face and Body For All Skin Types ... Kiehls Activated Sun Protector Sunscreen SPF 30 For Face and Body For All Skin Types …

Lisdexamfetamine

Lisdexamfetamine is a prodrug of dextroamphetamine, a central nervous system stimulant known as d-amphetamine, covalently attached to the naturally occurring amino acid L-lysine. Lisdexamfetamine is the first chemically formulated prodrug stimulant and was first approved by the FDA in April 2008. It was also approved by Health Canada in February...
Approved
Investigational
Matched Description: … system stimulant known as d-amphetamine,[A40246] covalently attached to the naturally occurring amino acid ... [A2230] by blocking dopamine and norepinephrine reuptake and increasing their levels in the extraneuronal ... [A2230] Lisdexamfetamine is the first chemically formulated prodrug stimulant [A40246] and was first …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …

Pertussis vaccine

Pertussis vaccine is under investigation in clinical trial NCT01698346 (Pertussis (Tdap) Vaccination in Pregnancy).
Approved
Investigational
Matched Mixtures name: … Diphtheria and Tetanus Toxoids With Pertussis Vaccine Adsorbed …

Fomepizole

Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.
Approved
Vet approved
Matched Description: … alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and …

Clofedanol

Clofedanol is a centrally-acting cough suppressant available in Canada under the trade name Ulone. It is not available in the United States.
Approved
Withdrawn
Matched Mixtures name: … Chlophedianol Hydrochloride, Dexchlorpheniramine Maleate, and Pseudoephedrine Hydrochloride …
Matched Categories: … Cough and Cold Preparations …

Mitoxantrone

An anthracenedione-derived antineoplastic agent.
Approved
Investigational
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …

Isopropyl myristate

Isopropyl myristate is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption. Isopropyl myristate has been largely studied and impulsed as a skin penetration enhancer. At the moment the primary usage for which isopropyl myristate is formally indicated is as the active...
Approved
Experimental
Matched Description: … Isopropyl myristate has been largely studied and impulsed as a skin penetration enhancer. ... Isopropyl myristate is a moisturizer with polar characteristics used in cosmetics and topical medical …
Matched Categories: … Scabicides and Pediculicides …

Luteinizing hormone

Approved
Matched Mixtures name: … MENOGON 75 IU Powder and Solvent for solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Acetazolamide

One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is...
Approved
Vet approved
Matched Description: … (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) ... It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures ... anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and …
Matched Categories: … Sulfur Compounds ... Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Sulfadiazine

One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
Approved
Investigational
Vet approved
Matched Description: … combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and …
Matched Categories: … Sulfur Compounds ... sulfadiazine and tetroxoprim ... Sulfonamides and trimethoprim ... sulfadiazine and trimethoprim ... Genito Urinary System and Sex Hormones …

Enfuvirtide

Enfuvirtide is a 36 amino acid biomimetic peptide that is structurally similar to the HIV proteins that are responsible for the fusion of the virus to cell membranes and subsequent intracellular uptake. The first agent in the novel class of antiretroviral drugs called HIV fusion inhibitors, enfuvirtide works by inhibiting...
Approved
Investigational
Matched Description: … Enfuvirtide is a 36 amino acid biomimetic peptide that is structurally similar to the HIV proteins that ... are responsible for the fusion of the virus to cell membranes and subsequent intracellular uptake. …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Pancrelipase

Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands. The pancrelipase mixture was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010. For further information on the components of this mixture...
Approved
Investigational
Matched Description: … Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and ... [L2510] For further information on the components of this mixture please visit [DB11065], [DB11066] and ... [L2509] The pancrelipase mixture was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved …
Matched Mixtures name: … Pancreatin and Enzyme Formula - Tablet …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Oxaprozin

Oxaprozin is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID), used to relieve the inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis.
Approved
Matched Iupac: … 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid …
Matched Description: … joint pain associated with osteoarthritis and rheumatoid arthritis. ... non-steroidal anti-inflammatory drug (NSAID), used to relieve the inflammation, swelling, stiffness, and …
Matched Categories: … Arylpropionic acid NSAIDS ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …

Sulfisoxazole

A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.
Approved
Vet approved
Matched Description: … A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive …
Matched Categories: … Sulfur Compounds ... Sulfonamides and trimethoprim ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Tetracosactide

Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone. ACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production of corticosteroids in the adrenal cortex. Tetracosactide exhibits the same...
Approved
Matched Iupac: … methylbutanamido]hexanamido]-3-methylbutanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxylic acid …
Matched Description: … Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Anterior Pituitary Lobe Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Tioguanine

An antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
Approved
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Secretin human

Human secretin is a gastrointestinal peptide hormone that regulates secretions in the stomach, pancreas, and liver. The hormone is produced from the enterochromaffin cells in the duodenum in response to the duodenal content with the pH less than 4.5 . The main action of secretin is to stimulate the pancreas...
Approved
Matched Description: … The carboxyl-terminal amino acid, valine, is amidated. ... It contains an amino acid sequence identical to the naturally occurring hormone consisting of 27 amino ... of pancreatic exocrine dysfunction and the diagnosis of gastrinoma, and facilitate the identification …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Mepyramine

Mepyramine, or pyrilamine, targets the H1 receptor. It is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect. It has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered to be an unapproved prescription medication...
Approved
Vet approved
Matched Description: … However, it rapidly permeates the brain and so often causes drowsiness as a side effect. ... It has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered …
Matched Mixtures name: … Acetaminophen,Caffeine and Pyrilamine Maleate ... Pyrilamine Maleate and Phenylephrine Hydrochloride …
Matched Categories: … Hypnotics and Sedatives …

Erythropoietin

Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO...
Approved
Matched Description: … The product contains the identical amino acid sequence of isolated natural erythropoietin and has the ... Epoetin alfa is a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using ... and displays equivalent clinical efficacy, potency, and purity to the reference product [A7504]. …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …

Flumazenil

Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system.
Approved
Matched Description: … Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that …

Betazole

A histamine H2 agonist used clinically to test gastric secretory function.
Approved

Uracil mustard

Nitrogen mustard derivative of uracil. It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage.
Approved
Matched Description: … and bone marrow damage. ... It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Eltrombopag

Eltrombopag is used to treat low blood platelet counts in adults with chronic immune (idiopathic) thrombocytopenia (ITP), when certain other medicines, or surgery to remove the spleen, have not worked well enough. ITP is a condition that may cause unusual bruising or bleeding due to an abnormally low number of...
Approved
Matched Iupac: … methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-ylidene]hydrazin-1-yl}-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid …
Matched Description: … thrombocytopenia (low blood platelet counts) in patients with chronic hepatitis C to allow them to initiate and …
Matched Categories: … Blood and Blood Forming Organs …

Tenapanor

Tenapanor is a novel, small molecule medication approved in September 2019 for the treatment of constipation-predominant irritable bowel-syndrome (IBS-C). It was first designed and synthesized in 2012. As an inhibitor of the sodium/hydrogen exchanger isoform 3 (NHE3) transporter, it is the first and currently only medication within its class[A185489,A185492,A185495] and...
Approved
Investigational
Matched Description: … [L8558] It was first designed and synthesized in 2012. ... currently only medication within its class[A185489,A185492,A185495] and therefore exists as a novel ... A185492] As an inhibitor of the sodium/hydrogen exchanger isoform 3 (NHE3) transporter, it is the first and …
Matched Categories: … Sulfur Compounds ... Alimentary Tract and Metabolism …

Mipomersen

Mipomersen sodium, which was known as the investigational drug, isis-301012, is the salt form of a synthetic phosphorothioate oligonucleotide. Mipomersen sodium prevents the formation of apo B-100, resulting in a decrease in the levels of apolipoprotein B (apo B), low density lipoprotein (LDL), and total cholesterol. Mipomersen is indicated in...
Approved
Investigational
Matched Description: … , resulting in a decrease in the levels of apolipoprotein B (apo B), low density lipoprotein (LDL), and ... It is marketed under the brand name Kynamro in the United States, and the FDA label includes a black ... Specifically, elevations in the liver enzymes, i.e. transaminases, and in liver fat (hepatic steatosis …
Matched Categories: … Nucleic Acid Probes ... Nucleic Acids, Nucleotides, and Nucleosides …
Displaying drugs 476 - 500 of 15051 in total