Displaying drugs 5076 - 5100 of 11535 in total
Apadenoson
Apadenoson is a selective A2a adenosine receptor agonist designed for use as a pharmacologic stress agent in cardiac perfusion imaging studies. It is developed by Bristol-Myers Squibb and is in phase II of clinical trials.
Investigational
Matched Description: … Apadenoson is a selective A2a adenosine receptor agonist designed for use as a pharmacologic stress agent …
Matched Categories: … Adenosine A receptor agonists …
Matched Categories: … Adenosine A receptor agonists …
Proscillaridin
Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). Studies suggest the potential cytotoxic and anticancer property of proscillaridin, based on evidence of the drug potently disrupting topoisomerase I and II activity at nanomolar drug concentrations and triggering cell...
Experimental
Matched Description: … Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Diodone
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Aprobarbital
Aprobarbital is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant effects. A primary treatment indicated for the use of aprobarbital was subsequently insomnia. Aprobarbital was never as widely used as more common barbiturate derivatives...
Experimental
Illicit
Matched Description: … Aprobarbital is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. ... A primary treatment indicated for the use of aprobarbital was subsequently insomnia. …
Lenomorelin
Lenomorelin has been investigated for the treatment and basic science of Cancer, Alcoholism, Metabolism, Hypopituitarism, and Frailty Syndrome, among others.
Investigational
Alcuronium
A non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant.
Experimental
Matched Description: … A non-depolarizing skeletal muscle relaxant similar to [tubocurarine]. …
PPI-1019
Apan (PPI-1019) is developed by Praecis Pharmaceuticals to treat Alzheimer's Disease.
Investigational
Anecortave acetate
Anecortave acetate (Retaane) is an analog of cortisol acetate; among the modifications to the steroid are the removal of the 11ß hydroxyl OH group and an addition of a 21-acetate group. As a result of these modifications, anecortave acetate lacks the typical antiinflammatory and immunosuppressive properties of glucocorticoids.Alcon Inc. is...
Investigational
Matched Iupac: … 3bS,9aS,11aS)-1-hydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,11H,11aH-cyclopenta[a] …
Matched Description: … among the modifications to the steroid are the removal of the 11ß hydroxyl OH group and an addition of a ... As a result of these modifications, anecortave acetate lacks the typical antiinflammatory and immunosuppressive …
Matched Description: … among the modifications to the steroid are the removal of the 11ß hydroxyl OH group and an addition of a ... As a result of these modifications, anecortave acetate lacks the typical antiinflammatory and immunosuppressive …
NCX 1022
NCX is an NO-releasing derivative of hydrocortisone.
Investigational
Matched Iupac: … 1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Bevirimat
Bevirimat, also known as PA-457 or YK-FH312, is investigated in clinical trials for treating HIV infection. Bevirimat is a solid. This compound belongs to the androgens and derivatives, which are hydroxylated C19 steroid hormones. They are known to favour the development of masculine characteristics. They also show profound effects on...
Investigational
Matched Iupac: … carboxy-3,3-dimethylpropanoyl)oxy]-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-icosahydro-1H-cyclopenta[a] …
Matched Description: … Bevirimat is a solid. ... , a Chinese herb. ... Bevirimat is derived from a betulinic acid-like compound, first isolated from Syzygium claviflorum …
Matched Description: … Bevirimat is a solid. ... , a Chinese herb. ... Bevirimat is derived from a betulinic acid-like compound, first isolated from Syzygium claviflorum …
Algestone
Experimental
Matched Iupac: … acetyl-1,2-dihydroxy-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Furazolidone
A nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone binds bacterial DNA which leads to the gradual inhibition of monoamine oxidase. (From Martindale, The Extra Pharmacopoeia, 30th ed, p514)
Experimental
Vet approved
Matched Description: … A nitrofuran derivative with antiprotozoal and antibacterial activity. …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Avasimibe
Investigational
Paramethasone
A glucocorticoid with the general properties of corticosteroids. It has been used by mouth in the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary fludrocortisone. (From Martindale, The Extra Pharmacopoeia,...
Experimental
Matched Iupac: … dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … A glucocorticoid with the general properties of corticosteroids. …
Matched Description: … A glucocorticoid with the general properties of corticosteroids. …
Amrubicin
Amrubicin is a third-generation synthetic anthracycline currently in development for the treatment of small cell lung cancer. Pharmion licensed the rights to Amrubicin in November 2006. In 2002, Amrubicin was approved and launched for sale in Japan based on Phase 2 efficacy data in both SCLC and NSCLC. Since January...
Investigational
Matched Description: … Amrubicin is a third-generation synthetic anthracycline currently in development for the treatment of ... Since January 2005, Amrubicin has been marketed by Nippon Kayaku, a Japanese pharmaceutical firm focused …
Amprolium
Amprolium is a coccidiostat used in poultry.
Experimental
Vet approved
Matched Description: … Amprolium is a coccidiostat used in poultry. …
Anlotinib
Anlotinib has been investigated for the treatment of Non-small Cell Lung Cancer and Metastatic Colorectal Cancer.
Investigational
Prezatide copper
Prezatide is a tripeptide consisting of glycine, histidine, and lysine which readily forms a complex with copper ions . Prezatide is used in cosmetic products for the skin and hair. It is known to aid wound healing and its potential applications in chronic obstructive pulmonary disease and metastatic colon cancer...
Experimental
Matched Description: … Prezatide is a tripeptide consisting of glycine, histidine, and lysine which readily forms a complex …
Norgestomet
Norgestomet, also known as 11β-methyl-17-hydroxy-19-norprogesterone acetate, is a steroidal progestin used in veterinary medicine to control estrus and ovulation in cattle.
Vet approved
Matched Iupac: … 11aS)-1-acetyl-10,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Norgestomet, also known as 11β-methyl-17-hydroxy-19-norprogesterone acetate, is a steroidal progestin …
Matched Description: … Norgestomet, also known as 11β-methyl-17-hydroxy-19-norprogesterone acetate, is a steroidal progestin …
Melengestrol acetate
A 6-methyl progesterone acetate with reported glucocorticoid activity and effect on estrus.
Experimental
Matched Iupac: … acetyl-5,9a,11a-trimethyl-2-methylidene-7-oxo-1H,2H,3H,3aH,3bH,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … A 6-methyl progesterone acetate with reported glucocorticoid activity and effect on estrus. …
Matched Description: … A 6-methyl progesterone acetate with reported glucocorticoid activity and effect on estrus. …
Cortisone
A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to the active metabolite hydrocortisone. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)
Experimental
Matched Iupac: … 1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … A naturally occurring glucocorticoid. …
Matched Description: … A naturally occurring glucocorticoid. …
Butyrfentanyl
Butyrfentanyl or butyrylfentanyl (not to be confused with 3-methylfentanyl) is a potent short-acting synthetic opioid analgesic drug. It is an analog of fentanyl with roughly 1/30 the potency. Butyrfentanyl was first synthesized in 1961 by Janssen Pharmaceuticals as a new opioid analgesic. Butyrfentanyl has no current legitimate clinical applications, but...
Illicit
Matched Description: … [L7811] This compound is a schedule I controlled substance in the USA because it is a positional isomer ... Butyrfentanyl or butyrylfentanyl (not to be confused with 3-methylfentanyl) is a potent short-acting ... [L7811] Butyrfentanyl was first synthesized in 1961 by Janssen Pharmaceuticals as a new opioid analgesic …
AR-AO-14418
Experimental
3,4-Dihydroxybenzoic Acid
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Tetramethrin
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 5076 - 5100 of 11535 in total