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Displaying drugs 5126 - 5150 of 11493 in total

Ethanolamine

A viscous, hygroscopic amino alcohol with an ammoniacal odor. It is widely distributed in biological tissue and is a component of lecithin. It is used as a surfactant, fluorimetric reagent, and to remove CO2 and H2S from natural gas and other gases.
Experimental
Matched Description: … A viscous, hygroscopic amino alcohol with an ammoniacal odor. ... It is widely distributed in biological tissue and is a component of lecithin. ... It is used as a surfactant, fluorimetric reagent, and to remove CO2 and H2S from natural gas and other …

Lithium cation

Lithium was used during the 19th century to treat gout. Lithium salts such as lithium carbonate (Li2CO3), lithium citrate, and lithium orotate are mood stabilizers. They are used in the treatment of bipolar disorder, since unlike most other mood altering drugs, they counteract both mania and depression. Lithium can also...
Experimental
Matched Description: … It is also sometimes prescribed as a preventive treatment for migraine disease and cluster headaches. ... The active principle in these salts is the lithium ion Li+, which having a smaller diameter, can easily …

N-(indole-3-acetyl)-L-aspartic acid

Experimental

Antimonous acid

Experimental

Bafilomycin A1

The bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces griseus. These compounds all appear in the same fermentation and have similar biological activity. Bafilomycins are specific inhibitors of vacuolar-type H+-ATPase. (V-ATPase). The most commonly utilized bafilomycin is bafilomycin A1. This is a useful tool...
Experimental
Matched Description: … The bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces ... This is a useful tool as it can prevent the re-acidification of synaptic vesicles once they have undergone …

Coumermycin A1

Experimental

Alidornase alfa

Investigational

Alvocidib

Alvocidib is a synthetic flavonoid based on an extract from an Indian plant for the potential treatment of cancer. It works by inhibiting cyclin-dependent kinases, arresting cell division and causing apoptosis in non-small lung cancer cells.
Experimental
Investigational
Matched Description: … Alvocidib is a synthetic flavonoid based on an extract from an Indian plant for the potential treatment …

Rezatomidine

Rezatomidine has been used in trials studying the treatment of Fibromyalgia, Cystitis, Interstitial, Irritable Bowel Syndrome, and Diabetic Neuropathy, Painful.
Investigational

Avadomide

Avadomide is under investigation in clinical trial NCT02031419 (Novel Combinations of CC-122, CC-223, CC-292, and Rituximab in Diffuse Large B-cell Lymphoma and Follicular Lymphoma).
Investigational

Telapristone acetate

Telapristone acetate, an orally-available, selective progesterone receptor modulator, is in development to alleviate symptoms associated with both uterine fibroids and endometriosis.
Investigational
Matched Iupac: … phenyl]-1-(2-methoxyacetyl)-11a-methyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,10H,11H,11aH-cyclopenta[a] …

Asoprisnil

Asoprisnil (J867) is a selective progesterone receptor modulator. It can be used to treat progesterone sensitive myomata.
Investigational
Matched Iupac: … phenyl}-1-methoxy-1-(methoxymethyl)-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Asoprisnil (J867) is a selective progesterone receptor modulator. …

Chloroprednisone

Experimental
Matched Iupac: … hydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …

Corticosterone

An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)
Experimental
Matched Iupac: … 1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid …

Isoflupredone

Vet approved
Matched Iupac: … dihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …

Maxy-G34

MAXY-G34 is a pegylated variant of human granulocyte-colony stimulating factor (G-CSF). This variant contains multiple non-naturally occurring lysines that have been introduced into alpha helixes of wild type human G-CSF as PEGylation sites, and from which multiple undesired, naturally occurring lysines have been removed as compared to wild type human...
Investigational
Matched Description: … MAXY-G34 is a pegylated variant of human granulocyte-colony stimulating factor (G-CSF). ... attached at the amino terminal end of the protein and at two internal lysine residues, while Neulasta has a …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Rotenone

Rotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also toxic to fish.
Vet approved
Matched Categories: … Compounds used in a research, industrial, or household setting …

Tocotrienol

Tocotrienol has been investigated for the treatment of Cholesterol Lowering.
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …

Bevacizumab zirconium Zr-89

Bevacizumab zirconium Zr-89 is under investigation in clinical trial NCT01338090 (89Zr-bevacizumab PET Imaging in Patients With Neuroendocrine Tumors).
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …

Baicalein

Baicalein is under investigation in clinical trial NCT03830684 (A Randomized, Double-blind, Placebo-controlled, Multicenter and Phase ⅡA Clinical Trial for the Effectiveness and Safety of Baicalein Tablets in the Treatment of Improve Other Aspects of Healthy Adult With Influenza Fever).
Investigational
Matched Description: … Baicalein is under investigation in clinical trial NCT03830684 (A Randomized, Double-blind, Placebo-controlled …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Aprindine

Aprindine is a cardiac depressant used in arrhythmias.
Experimental
Matched Description: … Aprindine is a cardiac depressant used in arrhythmias. …

Amibegron

Amibegron is an agonist for atypical beta3-adrenoceptors which inhibits intestinal motility.
Investigational

Aplaviroc

A spiro-diketo-piperazine; a potent noncompetitive allosteric antagonist of the CCR5 receptor with concomitantly potent antiviral effects for HIV-1.
Investigational
Matched Description: … A spiro-diketo-piperazine; a potent noncompetitive allosteric antagonist of the CCR5 receptor with concomitantly …

ADH-1

Adherex's biotechnology compound, ADH-1, targets N-cadherin, a protein present on certain tumor cells and established tumor blood vessels. ADH-1 is currently in clinical development in a combination program with a range of chemotherapeutic agents to investigate the synergistic effects noted in our preclinical models. At the end of 2006, the...
Investigational
Matched Description: … ADH-1 is currently in clinical development in a combination program with a range of chemotherapeutic ... ADH-1 may have utility in a wide variety of cancers as N-cadherin is overexpressed in a variety of tumors ... Adherex's biotechnology compound, ADH-1, targets N-cadherin, a protein present on certain tumor cells …

AKV-9

Investigational
Displaying drugs 5126 - 5150 of 11493 in total