Displaying drugs 501 - 525 of 9605 in total
Ergotamine
A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.
Approved
Matched Synonyms: … (5'α)-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotoman-3',6',18-trione ... 12'-hydroxy-2'-methyl-5'α-(phenylmethyl)ergotaman-3',6',18-trione ... 12'-Hydroxy-2'-methyl-5'alpha-(phenylmethyl)ergotaman-3',6',18-trione …
Matched Iupac: … -4-carboxamide ... (4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6}] ... dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings ... Serotonin 5-HT1 Receptor Agonists ... Serotonin 5-HT2 Receptor Agonists …
Matched Iupac: … -4-carboxamide ... (4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6}] ... dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings ... Serotonin 5-HT1 Receptor Agonists ... Serotonin 5-HT2 Receptor Agonists …
Tavaborole
Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to Trichophyton rubrum or Trichophyton mentagrophytes infection. Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis...
Approved
Investigational
Matched Synonyms: … 5-Fluoro-2,1-benzoxaborol-1(3H)-ol ... 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole …
Matched Iupac: … 5-fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol …
Matched Iupac: … 5-fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol …
Ceftobiprole
Ceftobiprole is a fifth-generation semisynthetic cephalosporin antibacterial which is available commercially as the prodrug ceftobiprole medocaril. Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative bacteria, including antibiotic-resistant strains of Staphylcoccus aureus (methicillin-resistant Staphylococcus aureus; MRSA).
The EMA's Committee for Medicinal Products for Human Use (CHMP)...
Approved
Investigational
Matched Iupac: … -[1,3'-bipyrrolidin]-3-ylidene]methyl}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(N-hydroxyimino)acetamido]-8-oxo-3-{[(3E,3'R)-2-oxo …
Raxtozinameran
Approved
Pentastarch
Pentastarch is an artificial colloid (hydroxyethyl starch derivative). Pentastarch is characterized by presenting five hydroxyethyl groups, which signifies an approximate 50% hydroxyethylation. It is sold under the name Pentaspan by Bristol-Myers Squibb and is used for fluid resuscitation. When administered, pentastarch remains mainly in the circulatory system and hence, it...
Approved
Investigational
Ioxaglic acid
Ioxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during...
Approved
Investigational
Matched Iupac: … 3-[(2-hydroxyethyl)carbamoyl]-2,4,6-triiodo-5-(2-{[2,4,6-triiodo-3-(methylcarbamoyl)-5-(N-methylacetamido …
Plazomicin
Developed by Achaogen biopharmaceuticals, plazomicin is a next-generation aminoglycoside synthetically derived from DB12604. The structure of plazomicin was established via appending hydroxylaminobutyric acid to DB12604 at position 1 and 2-hydroxyethyl group at position 6' . It was designed to evade all clinically relevant aminoglycoside-modifying enzymes, which contribute to the main...
Approved
Investigational
Matched Iupac: … (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-4-{[(2S,3R)-3-amino-6-{[(2-hydroxyethyl)amino]methyl}-3,4-dihydro ... -2H-pyran-2-yl]oxy}-2-{[(2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)oxan-2-yl]oxy}-3-hydroxycyclohexyl …
Matched Salts cas: … 1380078-95-4 …
Matched Salts cas: … 1380078-95-4 …
Treprostinil
Treprostinil is a stable tricyclic analogue of prostacyclin that promotes the vasodilation of pulmonary and systemic arterial vascular beds and the inhibition of platelet aggregation.[L41855,L41860,L41865] It reduces symptoms in patients with pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease.[L41855,L41860] The first agent approved for the treatment...
Approved
Investigational
Matched Iupac: … -{[(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H,2H,3H,3aH,4H,9H,9aH-cyclopenta[b]naphthalen-5- …
Matched Description: … However, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room …
Matched Salts cas: … 289480-64-4 …
Matched Products: … REMODULIN 5 mg/ml Infusionslösung ... Treposa 5 mg/ml Infusionslösung ... Trisuva 5 mg/ml Infusionslösung …
Matched Description: … However, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room …
Matched Salts cas: … 289480-64-4 …
Matched Products: … REMODULIN 5 mg/ml Infusionslösung ... Treposa 5 mg/ml Infusionslösung ... Trisuva 5 mg/ml Infusionslösung …
Lomifylline
Approved
Matched Synonyms: … 7-(5-oxohexyl)theophylline …
Matched Iupac: … 1,3-dimethyl-7-(5-oxohexyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Matched Iupac: … 1,3-dimethyl-7-(5-oxohexyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Zaleplon
Zaleplon is a sedative/hypnotic, mainly used for insomnia. It is known as a nonbenzodiazepine hypnotic. Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of the benzodiazepines. Zaleplon is a schedule IV drug in the United States.
Approved
Illicit
Investigational
Matched Products: … SONATA ® 5 MG. CAPSULAS …
Avacincaptad pegol
Avacincaptad pegol is an RNA aptamer covalently bound to a branched polyethylene glycol (PEG) molecule. It was developed to treat an advanced form of age-related macular degeneration (AMD) called geographic atrophy (GA). AMD is the leading cause of vision loss in developed countries for people over 50 years old, with...
Approved
Investigational
Matched Description: … [A260801]
Avacincaptag pegol was approved by the FDA on August 4, 2023, under the brand name IZERVAY …
Pralsetinib
Pralsetinib, similar to the previously approved selpercatinib, is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes.[A202055, A219751, L15986] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark of many cancers, including non-small cell lung cancer. Although multikinase inhibitors, including cabozantinib, ponatinib,...
Approved
Investigational
Matched Iupac: … (1s,4s)-N-[(1S)-1-[6-(4-fluoro-1H-pyrazol-1-yl)pyridin-3-yl]ethyl]-1-methoxy-4-{4-methyl-6-[(5-methyl …
Matched Description: … ARROW (NCT03037385) is still ongoing, pralsetinib was granted accelerated FDA approval on September 4, …
Matched Description: … ARROW (NCT03037385) is still ongoing, pralsetinib was granted accelerated FDA approval on September 4, …
Procaine benzylpenicillin
Procaine benzylpenicillin (INN), also known as procaine G penicillin, is an injectable antiobiotic. It is a poorly soluble salt form of penicillin which is a combination of naturally occuring benzylpenicillin (penicillin G) and the local anaesthetic agent procaine in equimolar amounts. Procaine benzylpenicillin is administered by deep intramuscular injection. It...
Approved
Vet approved
Matched Iupac: … ; 2-(diethylamino)ethyl 4-aminobenzoate ... (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Antithymocyte immunoglobulin (rabbit)
Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of...
Approved
Matched Products: … Thymoglobuline 5 mg/ml - Pulver zur Herstellung einer Infusionslösung ... THYMOGLOBULİNE 5 MG-ML IV İNFÜZYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON ... GRAFALON 5 ML IV INFUZYONLUK COZELTI KONSANTRESI ICEREN FLAKON, 1 ADET …
Tezacaftor
Tezacaftor is a drug of the cystic fibrosis transmembrane conductance regulator (CFTR) potentiator class. It was developed by Vertex Pharmaceuticals and FDA approved in combination with ivacaftor to manage cystic fibrosis. This drug was approved by the FDA on February 12, 2018. Cystic Fibrosis is an autosomal recessive disorder caused...
Approved
Investigational
Matched Iupac: … -2-yl)-1H-indol-5-yl}cyclopropane-1-carboxamide ... 1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)-N-{1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan …
Midodrine
An ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Approved
Matched Synonyms: … 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol …
Matched Products: … MIDODRINA 5 MG ... GUTRON TABLET 5 mg ... Gutron 5 mg - Tabletten …
Matched Products: … MIDODRINA 5 MG ... GUTRON TABLET 5 mg ... Gutron 5 mg - Tabletten …
Calcipotriol
Calcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.
Approved
Matched Iupac: … -1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol ... (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5S)-5-cyclopropyl-5-hydroxypent-3-en-2-yl]-7a-methyl-octahydro …
Matched Salts cas: … 147657-22-5 …
Matched Mixtures name: … Calcipotriene 0.005% / Niacinamide 4% …
Matched Salts cas: … 147657-22-5 …
Matched Mixtures name: … Calcipotriene 0.005% / Niacinamide 4% …
Bivalirudin
Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously. Because it can cause blood stagnation, it is important to monitor changes in...
Approved
Investigational
Matched Iupac: … ]pyrrolidin-2-yl]formamido}-5-carbamimidamidopentanoyl]pyrrolidin-2-yl]formamido}acetamido)acetamido] ... (4S)-4-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-(2-{2-[2-(2-{[(2S)-1-[(2S)-2-{[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl ... ]-4-{[(2S,3S)-1-[(2S)-2-{[(1S)-3-carboxy-1-{[(1S)-3-carboxy-1-{[(1S)-1-{[(1S)-1-carboxy-3-methylbutyl ... ]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}propyl]carbamoyl}propyl]carbamoyl}pyrrolidin-1-yl]-3-methyl ... acetamido}acetamido)-3-carbamoylpropanamido]acetamido}-3-carboxypropanamido]-3-phenylpropanamido]-4-carboxybutanamido …
Human papillomavirus type 58 L1 capsid protein antigen
Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 58. The vaccine is prepared from the purified...
Approved
Elapegademase
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Description: … Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on October 5, …
Insulin glulisine
Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … Due to its duration of action of around 5 hours, Apidra is considered "bolus insulin" as it provides …
Matched Products: … APIDRA OPTIPEN 100 IU/ML SC KULLANIMI İÇİN ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... APIDRA 100 U/ML SOLOSTAR ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 5 ADET …
Matched Products: … APIDRA OPTIPEN 100 IU/ML SC KULLANIMI İÇİN ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... APIDRA 100 U/ML SOLOSTAR ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 5 ADET …
Alfacalcidol
Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of vitamin D. It plays an essential function in calcium homeostasis and bone metabolism. Alfacaldisol is activated by the enzyme 25-hydroxylase in the liver to mediate its effects in the body, or most importantly, the kidneys and bones. The pharmacological...
Approved
Nutraceutical
Matched Iupac: … (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-octahydro-1H-inden-4-ylidene] ... ethylidene}-4-methylidenecyclohexane-1,3-diol …
Imipenem
Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains.[label] It is stable to many beta-lactamases. Similar compounds include meropenem, known for having greater activity against Gram negative bacteria, and the newer ertapenem which exhibits...
Approved
Matched Salts cas: … 74431-23-5 …
Bezafibrate
Antilipemic agent that lowers cholesterol and triglycerides. It decreases low density lipoproteins and increases high density lipoproteins.
Approved
Investigational
Matched Iupac: … 2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-2-methylpropanoic acid …
Technetium Tc-99m disofenin
Technetium Tc-99m disofenin is a radiopharmaceutical agent used in hepatobiliary imaging for diagnostic purposes. It is well suited for both planar and single photon tomographic scintigraphy to quantitatively measure the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary system. It is available as...
Approved
Displaying drugs 501 - 525 of 9605 in total