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Displaying drugs 501 - 525 of 10387 in total
Penicillamine
Penicillamine is a pharmaceutical of the chelator class. The pharmaceutical form is D-penicillamine, as L-penicillamine is toxic (it inhibits the action of pyridoxine). It is an α-amino acid metabolite of penicillin, although it has no antibiotic properties.
Approved
Matched Synonyms: … (S)-2-amino-3-mercapto-3-methylbutanoic acid ... 3-mercapto-D-valine …
Matched Iupac: … (2S)-2-amino-3-methyl-3-sulfanylbutanoic acid …
Matched Iupac: … (2S)-2-amino-3-methyl-3-sulfanylbutanoic acid …
Chlormerodrin
Chlormerodrin is a mercurial compound with toxic side effects that was previously used as a diuretic. The radiolabeled form has been used as a diagnostic and research tool. It is no longer used and has been replaced with new classes of diuretic drugs.
Approved
Withdrawn
Matched Synonyms: … 1-[3-(chloromercuri)-2-methoxypropyl]urea ... {3-[(aminocarbonyl)amino]-2-methoxypropyl}chloromercury …
Matched Iupac: … [3-(chloromercurio)-2-methoxypropyl]urea …
Matched Iupac: … [3-(chloromercurio)-2-methoxypropyl]urea …
Brilliant green cation
Brilliant green, or ethanaminium, is a derivative of triarylmethane dye that has been used as a dye to color silk and wool. Due to its inhibitory actions against Gram positive microorganisms, brilliant green can be found in antiseptic products such as solutions and swabs used to prevent infection.
Approved
Vet approved
Durvalumab
Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody and a novel immune-checkpoint inhibitor for cancer treatment. Produced by recombinant DNA technology in Chinese Hamster Ovary (CHO) cell suspension culture, durvalumab is a programmed death-ligand 1 (PD-L1) blocking antibody that works to promote normal immune responses that attack tumour...
Approved
Investigational
Tinzaparin
Tinzaparin is a low molecular weight heparin (LMWH), produced by enzymatic depolymerization of unfractionated heparin from porcine intestinal mucosa. It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. Tinzaparin is composed of molecules with and without a special site for high affinity binding...
Approved
Matched Products: … INNOHEP INYECTABLE VIAL 2 MG 10.000 UI/ML. ... INNOHEP INYECTABLE VIAL 2 ML. 20.000 UI/ML. ... INNOHEP 10.000 IU/0.5 ML KULLANIMA HAZIR DOLU ENJEKTÖRDE ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, 2 ADET …
Baricitinib
Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis. By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune responses. Baricitinib was...
Approved
Investigational
Matched Iupac: … 2-[1-(ethanesulfonyl)-3-(4-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1H-pyrazol-1-yl)azetidin-3-yl]acetonitrile …
Matched Categories: … MATE 2 Inhibitors ... MATE 2 Substrates ... Heterocyclic Compounds, 2-Ring ... MATE 2 Substrates with a Narrow Therapeutic Index …
Matched Products: … โอลูเมียนท์ (2 มก.) ... UNAMİTY 2 MG FİLM KAPLI TABLET, 7 ADET ... UNAMİTY 2 MG FİLM KAPLI TABLET, 28 ADET …
Matched Categories: … MATE 2 Inhibitors ... MATE 2 Substrates ... Heterocyclic Compounds, 2-Ring ... MATE 2 Substrates with a Narrow Therapeutic Index …
Matched Products: … โอลูเมียนท์ (2 มก.) ... UNAMİTY 2 MG FİLM KAPLI TABLET, 7 ADET ... UNAMİTY 2 MG FİLM KAPLI TABLET, 28 ADET …
Bordetella pertussis toxoid antigen (glutaraldehyde inactivated)
Approved
Investigational
Matched Mixtures name: … 3 ANTIGEN ... ADACEL 0,5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 5 ADET ... FORMALDEHYDE INACTIVATED), BORDETELLA PERTUSSIS PERTACTIN ANTIGEN, and BORDETELLA PERTUSSIS FIMBRIAE 2/ …
Trofinetide
Trofinetide is a novel synthetic analog of glypromate, also known as glycine–proline–glutamate (GPE), a naturally occurring protein in the brain and the N-terminal tripeptide of insulin-like growth factor 1 (IGF-1). Trofinetide was approved by the FDA on March 10, 2023, for the treatment of Rett syndrome,[L45718,L45748] which is an X-linked...
Approved
Investigational
Matched Synonyms: … glycyl-L-2-methylprolyl-L-glutamic acid …
Matched Iupac: … (2S)-2-{[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidin-2-yl]formamido}pentanedioic acid …
Matched Iupac: … (2S)-2-{[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidin-2-yl]formamido}pentanedioic acid …
Influenza A virus A/Brisbane/59/2007 (H1N1) hemagglutinin antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Investigational
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …
Pamidronic acid
Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to neridronic acid and alendronic acid. Pamidronic acid was first described in the literature in 1977. The second generation bisphosphonates are less common as third generation bisphosphonates, such as ibandronic acid, zoledronic acid, minodronic acid, and risedronic acid are becoming...
Approved
Matched Iupac: … (3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid …
Matched Salts cas: … 109552-15-0 …
Matched Products: … ./5 มล., 30 มก./10 มล. ... Pamidronate Disodium Omega 3 mg/ml ... MENEDRON-L 30 MG IV ENJEKSİYONLUK LİYOFİLİZE TOZ İÇEREN FLAKON (3 FLAKON) …
Matched Salts cas: … 109552-15-0 …
Matched Products: … ./5 มล., 30 มก./10 มล. ... Pamidronate Disodium Omega 3 mg/ml ... MENEDRON-L 30 MG IV ENJEKSİYONLUK LİYOFİLİZE TOZ İÇEREN FLAKON (3 FLAKON) …
Mechlorethamine
A vesicant and necrotizing irritant destructive to mucous membranes, mechlorethamine is an alkylating drug. It was formerly used as a war gas. The hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. It causes severe gastrointestinal and bone marrow damage.
The FDA granted marketing approval for the orphan...
Approved
Investigational
Matched Synonyms: … bis(2-chloroethyl)methylamine ... methylbis(2-chloroethyl)amine ... N-methyl-bis(2-chloroethyl)amine …
Matched Iupac: … bis(2-chloroethyl)(methyl)amine …
Matched Iupac: … bis(2-chloroethyl)(methyl)amine …
Regorafenib
Regorafenib is an orally-administered inhibitor of multiple kinases. It is used for the treatment of metastatic colorectal cancer, advanced gastrointestinal stromal tumours, and hepatocellular carcinoma. FDA approved on September 27, 2012. Approved use of Regorafenib was expanded to treat Hepatocellular Carcinoma in April 2017.
Approved
Matched Iupac: … 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide …
Matched Salts cas: … 1019206-88-2 …
Matched Salts cas: … 1019206-88-2 …
Norgestimate
Norgestimate was first described in the literature in 1977. It was developed by Ortho Pharmaceutical Corporation as part of an effort to develop new hormonal contraceptives with reduced adverse effects. It is commonly formulated with ethinylestradiol as a combined oral contraceptive that can also be used to treat moderate acne...
Approved
Investigational
Matched Synonyms: … (17α)-17-(Acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one 3-oxime ... d-13β-Ethyl-17α-ethynyl-17β-acetoxygon-4-en-3-one oxime ... (+)-13-Ethyl-17-hydroxy-18,19-dinor-17α-pregn-4-en-20-yn-3-one oxime acetate (ester) …
Aflibercept
Aflibercept is a recombinant protein composed of the binding domains of two human vascular endothelial growth factor (VEGF) receptors, VEGFR1 and VEGFR2, fused with the Fc region of human immunoglobulin gamma 1 (IgG1). Structurally, Aflibercept is a dimeric glycoprotein with a protein molecular weight of 96.9 kilo Daltons (kDa). It...
Approved
Matched Description: … [A261281,A261286] Due to the 2 fused VEGFR, aflibercept has a higher affinity to the cognate ligands …
Matched Products: … ZALTRAP 100MG/4ML INFUZYONLUK KONSANTRE COZELTI İÇEREN FLAKON, 3 ADET …
Matched Products: … ZALTRAP 100MG/4ML INFUZYONLUK KONSANTRE COZELTI İÇEREN FLAKON, 3 ADET …
Methyltestosterone
A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methyltestosterone is a schedule III drug in the US.
Approved
Matched Synonyms: … 17α-methyl-Δ4-androsten-17β-ol-3-one ... 17-beta-Hydroxy-17-methylandrost-4-en-3-one ... 17alpha-Methyl-3-oxo-4-androsten-17beta-ol …
Matched Categories: … 3-Oxoandrosten (4) Derivatives …
Matched Categories: … 3-Oxoandrosten (4) Derivatives …
Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) antigen (UV, formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …
Amiloxate
Amiloxate is an EMA-approved chemical UV-filter found in over-the-counter sunscreen products at concentrations up to 10%m . It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity .
Approved
Matched Synonyms: … 3-(4-Methoxyphenyl)-2-propenoic acid, 3-methylbutyl ester …
Matched Iupac: … 3-methylbutyl (2E)-3-(4-methoxyphenyl)prop-2-enoate …
Matched Iupac: … 3-methylbutyl (2E)-3-(4-methoxyphenyl)prop-2-enoate …
Finafloxacin
Finafloxacin is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. Finafloxacin is marketed by Novartis under the brand Xtoro™, and was approved by the FDA in December 2014.
Approved
Investigational
Matched Synonyms: … -1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl]-4-oxo-1,4-dihydro-3- …
Matched Iupac: … 7aS)-octahydropyrrolo[3,4-b]morpholin-6-yl]-8-cyano-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 7aS)-octahydropyrrolo[3,4-b]morpholin-6-yl]-8-cyano-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Givosiran
Givosiran is a small interfering RNA (siRNA) directed towards 5-aminolevulinic acid synthase, a critical enzyme in the heme biosynthesis pathway. It is manufactured by Alnylam Pharmaceuticals and was first approved for use in the United States in November 2019 for the treatment of adults with acute hepatic porphyria, a genetic...
Approved
Investigational
Matched Description: … Givosiran is a small interfering RNA (siRNA) directed towards 5-aminolevulinic acid synthase, a critical …
Influenza B virus B/Washington/02/2019 recombinant hemagglutinin antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …
Meclofenamic acid
A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
Approved
Vet approved
Matched Synonyms: … N-(2,6-dichloro-3-methylphenyl)anthranilic acid ... N-(3-methyl-2,6-dichlorophenyl)anthranilic acid …
Matched Iupac: … 2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid …
Matched Salts cas: … 67254-91-5 …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Iupac: … 2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid …
Matched Salts cas: … 67254-91-5 …
Matched Categories: … Non COX-2 selective NSAIDS …
Colloidal oatmeal
Colloidal oatmeal is produced by grinding fine granules of oatmeal and boiling it to extract the colloidal material. It contains high concentrations of starches and beta-glucan that exhibits water-absorbing properties. Phenols are also contained in colloidal oatmeal, which possess antioxidant and anti-inflammatory activities, as well as UV-absorbing activity. Colloidal oatmeal...
Approved
Nutraceutical
Matched Mixtures name: … Pediadermics Eczema 3 ... 5% Oat Facial Cleanser …
Matched Products: … 3-In-1 Relief CVS ... ZO MEDICAL 3-STEP PEEL Kit ... Eczema Care Moisturizing 3 oz. …
Matched Products: … 3-In-1 Relief CVS ... ZO MEDICAL 3-STEP PEEL Kit ... Eczema Care Moisturizing 3 oz. …
Erlotinib
Erlotinib is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase that is used in the treatment of non-small cell lung cancer, pancreatic cancer and several other types of cancer. It is typically marketed under the trade name Tarceva. Erlotinib binds to the epidermal growth factor receptor (EGFR)...
Approved
Investigational
Matched Synonyms: … [6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine …
Matched Iupac: … N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Bictegravir
Bictegravir is a recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 infection. It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet.
Approved
Investigational
Matched Iupac: … ^{2,11}.0^{4,9}]hexadeca-4,7-diene-7-carboxamide ... (1S,11R,13R)-5-hydroxy-3,6-dioxo-N-[(2,4,6-trifluorophenyl)methyl]-12-oxa-2,9-diazatetracyclo[11.2.1.0 …
Matched Description: … approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 ... It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet. …
Matched Description: … approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 ... It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet. …
Desonide
A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses.
Approved
Investigational
Matched Iupac: … 10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosa-14,17-dien-16-one ... (1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[ …
Displaying drugs 501 - 525 of 10387 in total