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Displaying drugs 501 - 525 of 5775 in total
Olesoxime is a cholesterol-like small molecule that has demonstrated a remarkable neuroprotective profile in a battery of both in vitro and in vivo preclinical models. For example, it has demonstrated the ability to prevent neurodegeneration, enhance nerve function and accelerate neuroregeneration following nerve trauma.[A3282,A253233]
Investigational
Matched Synonyms: … 4-Cholesten-3-one, oxime ... cholest-4-en-3-one, oxime ... (EZ)-N-(CHOLEST-4-EN-3-YLIDENE)HYDROXYLAMINE …
Matched Iupac: … N-[(1R,3aS,3bS,7E,9aR,9bS,11aR)-9a,11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1H,2H,3H,3aH,3bH,4H,5H,7H …
Matched Description: … small molecule that has demonstrated a remarkable neuroprotective profile in a battery of both in vitro and ... For example, it has demonstrated the ability to prevent neurodegeneration, enhance nerve function and
Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Iupac: … (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-(acetyloxy)-15-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy ... -3-phenylpropanoyl]oxy}-1,9,12-trihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^{3,10 …
Matched Description: … chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and ... Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel]. ... microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Oncotaxel Concentrate and solvent for solution for infusion 40 mg/ ml …
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Synonyms: … DL-4-Amino-3-p-chlorophenylbutanoic acid ... 4-Amino-3-(4-chlorophenyl)butyric acid ... beta-(Aminomethyl)-p-chlorohydrocinnamic acid
Matched Iupac: … 4-amino-3-(4-chlorophenyl)butanoic acid
Matched Description: … Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. ... [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the ... used to manage severe muscle spasms of cerebral or spinal cord origins, including multiple sclerosis and
Matched Salts cas: … 28311-31-1 …
Matched Salts name: … Baclofen hydrochloride
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... gamma-Aminobutyric Acid-ergic Agonist …
Acacia allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Plants and plant parts, gum, acacia or arabic acacia senegal …
Approved
Experimental
Matched Synonyms: … Zirconium hydroxychloride ... Zirconyl hydroxychloride
Experimental
Matched Synonyms: … Acido iocarmico ... Iocarmic acid ... Acidum iocarmicum …
Matched Name: … Iocarmic acid
Matched Iupac: … )benzoic acid ... 3-(5-{[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)phenyl]carbamoyl}pentanamido)-2,4,6-triiodo-5-(methylcarbamoyl …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... iocarmic acid ... Triiodobenzoic Acids
Experimental
Matched Synonyms: … 3-(oxidosulfanyl)-L-alanine ... cysteine S-oxide ... L-cysteine S-oxide
Matched Iupac: … (2R)-2-amino-3-sulfinylpropanoic acid
Experimental
Matched Synonyms: … Hydriodic acid ... Acide iodhydrique ... Acido yodhidrico …
A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of...
Approved
Nutraceutical
Matched Synonyms: … Amber acid ... Acide succinique ... Succinic acid
Matched Name: … Succinic acid
Matched Iupac: … butanedioic acid
Matched Description: … A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine ... , the manufacture of lacquers, and to make perfume esters. ... It is also used in foods as a sequestrant, buffer, and a neutralizing agent. …
Matched Mixtures name: … Iron Fumarate and Aspartate, Glycinate, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium Threonate ... Iron Aspartate Glycinate and Polysaccharide Complex, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium ... Iron Aspartate, Glycinate, Ascorbic Calcium, Vitamin B12, Calcium Threonate and Succinic Acid
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids
Hydroxyurea is a non-alkylating antineoplastic agent that was first synthesized in 1869 but was not characterized biologically until 1928. It was first approved by the FDA in 1998 for the treatment of sickle cell anemia in adults. Although clinical evidence on the efficacy of hydroxyurea in certain conditions exists, hydroxyurea...
Approved
Matched Synonyms: … Carbamohydroxamic acid ... Carbamohydroximic acid ... Carbamoyl oxime
Matched Description: … adherence, the need for therapeutic monitoring, and serious side effects of secondary cancer and birth ... conditions exists, hydroxyurea is used sparingly in clinical settings, largely due to lack of knowledge and
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Antineoplastic and Immunomodulating Agents …
Clodronic acid is a first generation bisphosphonate similar to etidronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. clodronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Investigational
Vet approved
Matched Synonyms: … Clodronic acid ... Acido clodronico ... Acide clodronique …
Matched Name: … Clodronic acid
Matched Iupac: … [dichloro(phosphono)methyl]phosphonic acid
Matched Description: … Clodronic acid is a first generation bisphosphonate similar to [etidronic acid] and [tiludronic acid] ... ], [ibandronic acid], [minodronic acid], and [risedronic acid]. ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and
Matched Categories: … clodronic acid ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … ACIDO CLODRONICO SANDOZ ... ACIDO CLODRONICO EG ... ACIDO CLODRONICO DOC GENERICI …
A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … 3-carboxy-3-hydroxypentane-1,5-dioic acid ... Acidum citricum ... Anhydrous citric acid
Matched Name: … Citric acid
Matched Iupac: … 2-hydroxypropane-1,2,3-tricarboxylic acid
Matched Description: … [L14120] It is also used in combination with magnesium oxide to form magnesium citrate, an osmotic laxative ... The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability ... It is an acid compound found in citrus fruits. …
Matched Mixtures name: … Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid ... Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid
Matched Salts name: … Citric acid monohydrate …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Acyclic ... Acid Preparations ... citric acid ... Carboxylic Acids
Matched Products: … Citric Acid ... Citric Acid Wipes ... Aquacetic-30
Calcium lactate is a salt that consists of two lactate anions for each calcium cation (Ca2+). It is prepared commercially by the neutralization of lactic acid with calcium carbonate or calcium hydroxide. Approved by the FDA as a direct food substance affirmed as generally recognized as safe, calcium lactate is...
Approved
Investigational
Vet approved
Matched Synonyms: … 2-Hydroxypropanoic acid calcium salt ... Calcio lactato ... Calcium lactate …
Matched Name: … Calcium lactate …
Matched Iupac: … calcium bis(2-hydroxypropanoate) …
Matched Description: … It is prepared commercially by the neutralization of lactic acid with calcium carbonate or calcium hydroxide ... is used as a firming agent, flavoring agent, leavening agent, stabilizer, and thickener [L2741]. ... Calcium lactate is a salt that consists of two lactate anions for each calcium cation (Ca2+). …
Matched Mixtures name: … Calcium Magnesium Tablets Nu Life ... Calcium Lactate Et Magnesium Sulfate ... Calcium Ctr Srt …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids ... Alimentary Tract and Metabolism ... Calcium Salts ... calcium lactate …
Matched Products: … PHARMANIAGA CALCIUM TABLET 300 MG ... CALACTATE 300 TABLET ... CALAC TABLET 300 MG …
Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers....
Approved
Investigational
Matched International brands: … Oxis Turbuhaler …
Matched Description: … Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was ... of action (2-3 minutes), which is at least as fast as [salbutamol], combined with a long duration of ... [L10986] It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic …
Matched Salts cas: … 183814-30-4 …
Matched Mixtures name: … Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate …
Matched Categories: … Adrenergic beta-Agonists ... Adrenergic beta-2 Receptor Agonists ... formoterol and mometasone ... formoterol and budesonide ... formoterol and aclidinium bromide …
Matched Products: … OXIS ... OXIS TURBOHALER 6UG 60ED ... OXIS TURBOHALER 12UG 60ED …
A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.
Approved
Matched Synonyms: … 5-[3-(2-carboxy-4-oxo-4H-5-chromenyloxy)-2-hydroxypropoxy]-4-oxo-4H-2-chromenecarboxylic acid ... Cromoglicic acid ... Cromoglycic acid
Matched Name: … Cromoglicic acid
Matched Iupac: … 5-{3-[(2-carboxy-4-oxo-4H-chromen-5-yl)oxy]-2-hydroxypropoxy}-4-oxo-4H-chromene-2-carboxylic acid
Matched Description: … It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect …
Matched Salts cas: … 15826-37-6 …
Matched Categories: … cromoglicic acid ... cromoglicic acid ... cromoglicic acid ... cromoglicic acid ... cromoglicic acid
Coumarin derivative that acts as a long-acting oral anticoagulant.
Approved
Investigational
Matched Synonyms: … 3-(alpha-Ethylbenzyl)-4-hydroxycoumarin ... 3-(alpha-Phenylpropyl)-4-hydroxycoumarin ... 3-(1-Phenylpropyl)-4-hydroxycoumarin …
Matched Iupac: … 4-hydroxy-3-(1-phenylpropyl)-2H-chromen-2-one …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … PHENPROCOUMON ACIS 3MG TAB ... PHENPROGAMMA 3 ... MARCUPHEN ABZ 3 MG TAB …
A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)
Approved
Illicit
Matched Synonyms: … alpha-Benzoyltriethylamine ... alpha-Diethylaminopropiophenone …
Matched Salts name: … Diethylpropion hydrochloride
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Diethylpropion Hydrochloride ... Diethylpropion Hydrochloride ER ... Diethylpropion HydrochlorideER ER …
Caprylic acid is an eight-carbon chain fatty acid, also known systematically as octanoic acid. It is found naturally in coconuts and breast milk. It is an oily liquid with a slightly unpleasant rancid-like smell that is minimally soluble in water.
Investigational
Matched Synonyms: … Acide octanoïque ... Octoic acid ... Caprylic acid
Matched Name: … Caprylic acid
Matched Iupac: … octanoic acid
Matched Description: … Caprylic acid is an eight-carbon chain fatty acid, also known systematically as octanoic acid. ... It is found naturally in coconuts and breast milk. …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids
Investigational
Matched Synonyms: … Stearic acid, magnesium salt ... Octadecanoic acid, magnesium salt ... Magnesium distearate …
Matched Name: … Magnesium stearate …
Matched Iupac: … magnesium(2+) dioctadecanoate …
Matched Categories: … Fatty Acids
Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Synonyms: … (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin ... -9-yl 4-(2-(5-(3-(2,4-dihydroxy-5-isopropylphenyl)-5-hydroxy-4H-1,2,4-triazol-4-yl)-1H-indol-1-yl)ethyl …
Matched Description: … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking ... irinotecan was first commercially available in Japan in 1994 to treat various cancers such as lung, cervical and ... [A263376] Approved by the FDA in 1996,[A263366] irinotecan is used to treat colorectal cancer and pancreatic …
Matched Salts cas: … 136572-09-3
Matched Salts name: … Irinotecan hydrochloride ... Irinotecan hydrochloride hydrate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … IROTEN 300 MG/15 ML IV INFUZYON ICIN KONSANTRE COZELTI ICEREN FLAKON, 1 ADET ... İRONTU 300 MG/15 ML İ.V. İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET ... IRINOCAM 300 MG/15 ML IV PERFÜZYON İÇİN ÇÖZELTİ İÇEREN FLAKON …
Experimental
Matched Synonyms: … (2Z,3E)-6-Bromoindirubin-3'-oxime ... (2Z,3E)-6'-bromo-2,3'-biindole-2',3(1H,1'H)-dione 3-oxime
Matched Name: … 6-bromoindirubin-3'-oxime
Matched Iupac: … (Z,3E)-6'-bromo-3-(hydroxyimino)-1',2'-dihydro-1H,3H-[2,3'-biindolyliden]-2'-one …
Matched Categories: … Glycogen Synthase Kinase 3, antagonists & inhibitors …
A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [PubChem]
Approved
Investigational
Matched Iupac: … 3-{2-[benzyl(methyl)amino]ethyl} 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without ... It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents ... A potent calcium channel blockader with marked vasodilator action. …
Matched Salts cas: … 54527-84-3
Matched Salts name: … Nicardipine Hydrochloride
Matched Categories: … Calcium-Regulating Hormones and Agents ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists ... Calcium Channel Blockers ... Calcium Channel Blockers (Dihydropyridine) …
Matched Products: … Nicardipine Hydrochloride ... NICARDIPINE HYDROCHLORIDE ... Cardene
Experimental
Matched Name: … 3-Butylthiolane 1-Oxide
Matched Iupac: … (1S,3S)-3-butyl-1lambda4-thiolan-1-one …
Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone...
Approved
Investigational
Matched Synonyms: … 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran ... 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran ... 2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone …
Matched Iupac: … {2-[4-(2-butyl-1-benzofuran-3-carbonyl)-2,6-diiodophenoxy]ethyl}diethylamine …
Matched Description: … indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and ... Because of its ability to cause serious toxicity and possibly death, amiodarone use should be reserved …
Matched Salts name: … Amiodarone hydrochloride
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Calcium Channel Blockers ... alpha-Galactosidase, antagonists & inhibitors ... Medications that reduce magnesium levels …
Matched Products: … Amiodarone Omega ... Amiodarone Hydrochloride ... Amiodarone hydrochloride
Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone...
Approved
Illicit
Investigational
Matched Synonyms: … 4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one ... 4,5α-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one ... 4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one …
Matched Description: … [A178696] It is currently indicated as an immediate release product for moderate to severe pain and as …
Matched Salts cas: … 124-90-3
Matched Mixtures name: … Oxycodon/Naloxon Acino 10 mg/5 mg Retardtabletten ... Oxycodon/Naloxon Acino 20 mg/10 mg Retardtabletten ... Oxycodon/Naloxon Acino 40 mg/20 mg Retardtabletten …
Matched Salts name: … Oxycodone hydrochloride
Matched Categories: … oxycodone and acetylsalicylic acid ... oxycodone and naloxone ... oxycodone and naltrexone ... oxycodone and ibuprofen ... oxycodone and paracetamol …
Matched Products: … OXYCODON-HCL-ACINO 10MG ... OXYCODON-HCL-ACINO 20MG ... OXYCODON-HCL-ACINO 40MG …
Displaying drugs 501 - 525 of 5775 in total