Advanced Filter

Filter by Group

Filter by Market Availability

Displaying drugs 501 - 525 of 2489 in total
Velafermin was a novel investigational protein therapeutic, also known as fibroblast growth factor-20 (FGF-20), which promotes both epithelial and mesenchymal cell proliferation in vitro and has demonstrated activity in multiple animal models. Velafermin was investigated as a potential therapy for the prevention and treatment of oral mucositis by fostering the...
Investigational
Matched Synonyms: … RECOMBINANT HUMAN FIBROBLAST GROWTH FACTOR-20 ... FIBROBLAST GROWTH FACTOR 20 (HUMAN RECOMBINANT CG53135) …
Matched Description: … (FGF-20), which promotes both epithelial and mesenchymal cell proliferation in vitro and has demonstrated ... Velafermin was a novel investigational protein therapeutic, also known as fibroblast growth factor-20 ... by fostering the regeneration and repair of the cells lining the gastrointestinal tract. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Biological Factors ... Intercellular Signaling Peptides and Proteins …
Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Synonyms: … Antihemophilic factor (recombinant) porcine sequence ... ANTIHEMOPHILIC FACTOR (RECOMBINANT), PORCINE SEQUENCE ... Porcine recombinant factor VIII B-domain truncated …
Matched Description: … These autoantibodies neutralize circulating human factor VIII and create a functional deficiency of this ... B domain replaced with a twenty-four amino acid linker. ... Susoctocog alfa was approved by the FDA in October 2014 and is marketed under the brand name Obizur for …
Matched Categories: … Blood and Blood Forming Organs ... Blood Coagulation Factors
A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive.
Approved
Vet approved
Matched Synonyms: … Edetic acid ... Acido edetico ... Acide edetique …
Matched Name: … Edetic acid
Matched Iupac: … 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetic acid
Matched Description: … It is used in pharmaceutical manufacturing and as a food additive. …
Matched Categories: … Diet, Food, and Nutrition ... Decreased Coagulation Factor Activity ... Acids, Acyclic ... Carboxylic Acids
Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H)...
Approved
Investigational
Matched Synonyms: … Recombinant human coagulation factor IX, FC Fusion protein ... Coagulation factor IX recombinant immunoglubulin g1 fusion protein …
Matched Description: … ), leading to decreased levels of endogenous factor IX and increased susceptibility to recurrent bleeding ... Eftrenonacog alfa acts as a replacement therapy to restore the levels of factor IX and allow normal hemostasis ... It was first approved by the FDA in March 2014 and later approved by the EMA in May 2016. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Biological Factors ... Blood Coagulation Factors
Tienilic acid, or ticrynafen, is a diuretic drug with uric acid-lowering action which was marketed for the treatment of hypertension. It was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and hepatitis. (Manier et al., 1982)
Withdrawn
Matched Synonyms: … Tienilic acid ... Thienylic acid ... Acide tiénilique …
Matched Name: … Tienilic acid
Matched Iupac: … 2-[2,3-dichloro-4-(thiophene-2-carbonyl)phenoxy]acetic acid
Matched Description: … It was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and ... Tienilic acid, or ticrynafen, is a diuretic drug with uric acid-lowering action which was marketed for …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Hydroxy Acids ... tienilic acid ... Aryloxyacetic Acid Derivatives …
Investigational
Matched Synonyms: … Ciliary neurotrophic factor, recombinant human …
Matched Name: … Human ciliary neurotrophic factor, recombinant (E. coli) …
Investigational
Matched Synonyms: … RECOMBINANT HUMAN PLACENTAL GROWTH FACTOR
Matched Name: … Recombinant human placental growth factor (PLGF-131) …
Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. Being unstable in the pure form, hypochlorite is most commonly used for bleaching, disinfectation, and water treatment purposes in its salt form, sodium hypochlorite. Hypochlorite is often used as a chemical reagent for chlorination and oxidation...
Approved
Matched Description: … Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. ... Hypochlorite is often used as a chemical reagent for chlorination and oxidation reactions. ... Being unstable in the pure form, hypochlorite is most commonly used for bleaching, disinfectation, and
Matched Categories: … Antiseptics and Disinfectants ... Acids ... Acids, Noncarboxylic …
Matched Products: … SUPERCLEAN Micro Acid Hypochlorite Disinfectant …
Prednicarbate is a relatively new topical corticosteroid drug that displays a similar potency as hydrocortisone. It is used in the treatment of inflammatory skin diseases, such as atopic dermatitis. It has a favorable benefit-risk ratio, with an inflammatory action similar to that of a medium potency corticosteroid, but with a...
Approved
Investigational
Matched Description: … IL-1a is also found in fibroblasts, where it is responsible for proliferation, collagenase induction and
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … PREDNICARBAT ACIS CREME ... PREDNICARBAT ACIS SALBE ... PREDNICARBAT ACIS FETTSALB …
Acacia allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Plants and plant parts, gum, acacia or arabic acacia senegal …
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Synonyms: … 3-fluoro-4-phenylhydratropic acid ... 2-(2-fluorobiphenyl-4-yl)propanoic acid ... (±)-2-fluoro-α-methyl-4-biphenylacetic acid
Matched Iupac: … 2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid
Matched Description: … and analgesic activity. ... Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen. ... Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain ... Acids, Acyclic ... Carboxylic Acids
Matched Products: … Strepsils MaxPro Honey and Lemon lozenges 8.75mg …
Molgramostim has been used in trials studying the treatment of Bronchiectasis, Cystic Fibrosis, Pulmonary Alveolar Proteinosis, Acute Respiratory Distress Syndrome, and Autoimmune Pulmonary Alveolar Proteinosis.
Investigational
Matched Synonyms: … Granulocyte macrophage-colony stimulating factor
Matched Description: … Bronchiectasis, Cystic Fibrosis, Pulmonary Alveolar Proteinosis, Acute Respiratory Distress Syndrome, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins ... Biological Factors ... Colony-Stimulating Factors
Formic acid (systematically called methanoic acid) is the simplest carboxylic acid. It is an important intermediate in chemical synthesis and occurs naturally, most famously in the venom of bee and ant stings. It is commonly used as a preservative and antibacterial agent in livestock feed.
Experimental
Investigational
Matched Synonyms: … Aminic acid ... Formic acid ... Acide formique …
Matched Name: … Formic acid
Matched Iupac: … formic acid
Matched Description: … of bee and ant stings. ... It is commonly used as a preservative and antibacterial agent in livestock feed. ... It is an important intermediate in chemical synthesis and occurs naturally, most famously in the venom …
Matched Categories: … Blood Coagulation Factors ... Acids, Acyclic ... Carboxylic Acids
Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ion complexes. DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment...
Approved
Matched Synonyms: … Pentetic acid ... Diethylene triamine pentaacetic acid ... Diethylenetriamine pentaacetic acid
Matched Name: … Pentetic acid
Matched Iupac: … 2-[bis({2-[bis(carboxymethyl)amino]ethyl})amino]acetic acid
Matched Description: … acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ... DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment ... [L2242] DPTA was developed by the pharmaceutical company CIS US and FDA approved on April 14, 2004. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids
Matched Products: … Pentetic Acid
The insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and to circulate in the blood. This factor presents effects related to growth regulation, insulin-like and mitogenic activities. To perform its biological activities, this growth factor can present some dependence to somatotropin. It...
Experimental
Matched Synonyms: … Insulin-like growth factor 2 ... Insulin-like growth factor-2 ... Insulin-like growth factor-II …
Matched Name: … Insulin-like growth factor II …
Matched Description: … This factor presents effects related to growth regulation, insulin-like and mitogenic activities. ... the liver and to circulate in the blood. ... a major growth factor in adults. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Biological Factors ... Intercellular Signaling Peptides and Proteins …
Investigational
Matched Synonyms: … Acido ippurico ... Benzamidoacetic acid ... Benzoylaminoacetic acid
Matched Name: … Hippuric acid
Matched Iupac: … 2-(phenylformamido)acetic acid
Matched Categories: … Benzamides and benzamide derivatives ... Keto Acids ... Acids, Carbocyclic ... Carboxylic Acids
Ioxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during...
Approved
Investigational
Matched Synonyms: … Ioxaglic acid ... acido ioxaglico …
Matched Name: … Ioxaglic acid
Matched Iupac: … triiodo-5-(2-{[2,4,6-triiodo-3-(methylcarbamoyl)-5-(N-methylacetamido)phenyl]formamido}acetamido)benzoic acid
Matched Description: … Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray ... Ioxaglic acid has a low osmolarity and is associated with fewer side effects compared to older contrast ... , arthrography, cholangiography, urography, and computed tomography [L1889]. …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... ioxaglic acid ... Triiodobenzoic Acids
Acetrizoic acid presents the molecular formula of 3-acetamidol-2,4,6-triiodobenzoic acid and it is the first monomeric ionic compound used as an X-ray contrast agent. It was first synthesized by Wallingford in 1953 and it was filled in the FDA by the Johnson & Johnson subsidiary, Cilag Chemie AG, on February 8th,...
Withdrawn
Matched Synonyms: … Urokonic acid ... Acide acetrizoique …
Matched Name: … Acetrizoic acid
Matched Iupac: … 3-acetamido-2,4,6-triiodobenzoic acid
Matched Description: … Acetrizoic acid presents the molecular formula of 3-acetamidol-2,4,6-triiodobenzoic acid[L1702] and it ... [A32135] It was first synthesized by Wallingford in 1953[A32136] and it was filled in the FDA by the ... [L1704] Acetrizoic acid presents, in the FDA records, a category of drug substance with an inactive status …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... acetrizoic acid ... Triiodobenzoic Acids
Corticotropin-releasing factor is studied in the treatment of brain cancer. It is made naturally by the hypothalamus (a part of the brain) and can also be made in the laboratory. Human corticotropin-releasing factor may help reduce symptoms caused by edema (swelling) of the brain. It is a type of neurohormone,...
Investigational
Matched Synonyms: … Corticotropin-releasing factor ... Human corticotropin-releasing factor ... Corticotropin-releasing factor (human) …
Matched Description: … It is made naturally by the hypothalamus (a part of the brain) and can also be made in the laboratory ... Corticotropin-releasing factor is studied in the treatment of brain cancer. ... Human corticotropin-releasing factor may help reduce symptoms caused by edema (swelling) of the brain …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Experimental
Matched Synonyms: … Acido nitrico ... Acide nitrique ... Nitric acid, anhydrous …
Matched Name: … Nitric acid
Matched Iupac: … nitric acid
Matched Categories: … Acids ... Acids, Noncarboxylic …
Tiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly arthritis pain. It belongs to the arylpropionic acid (profen) group of nonsteroidal anti-inflammatory drugs (NSAIDs).
Approved
Matched Synonyms: … Tiaprofenic acid ... Acido tiaprofenico ... Acide tiaprofenique …
Matched Name: … Tiaprofenic acid
Matched Iupac: … 2-(5-benzoylthiophen-2-yl)propanoic acid
Matched Description: … Tiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly ... It belongs to the _arylpropionic acid_ (profen) group of nonsteroidal anti-inflammatory drugs (NSAIDs …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids
Matched Products: … Teva-tiaprofenic Acid
Tasonermin is recombinant soluble form tumor necrosis factor α produced via Escherichia coli cell culture. It was approved for use by the European Medicines Agency in April of 1999 for use as an adjunt to surgery for the subsequent removal of the tumor and in palliative care for irresectable soft...
Approved
Matched Synonyms: … Tumor necrosis factor, soluble form, nonglycosylated …
Matched Description: … Medicines Agency in April of 1999 for use as an adjunt to surgery for the subsequent removal of the tumor and ... Tasonermin is recombinant soluble form tumor necrosis factor α produced via _Escherichia coli_ …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
PF-05230907 is a recombinant activated Factor X variant.
Investigational
Matched Synonyms: … RECOMBINANT FACTOR XA VARIANT FXAI16L …
Matched Description: … PF-05230907 is a recombinant activated Factor X variant. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Biological Factors ... Blood Coagulation Factors
Lormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia . It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.
Approved
Matched Description: … It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations. …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
Matched Products: … LORMETAZEPAM ACIS 0.5MG ... LORMETAZEPAM ACIS 1.0MG ... LORMETAZEPAM ACIS 2.0MG …
Muplestim is under investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients With Cytopenia).
Investigational
Matched Synonyms: … Multipotential colony-stimulating factor ... MAST CELL GROWTH FACTOR (NONGLYCOSYLATED) ... P-CELL-STIMULATING FACTOR (NONGLYCOSYLATED) …
Matched Description: … investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Biological Factors ... Colony-Stimulating Factors ... Hematopoietic Cell Growth Factors
Displaying drugs 501 - 525 of 2489 in total