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Displaying drugs 501 - 525 of 2733 in total

Darbepoetin alfa

Human erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.
Approved
Investigational
Matched Synonyms: … Darbepoetin alfa,recombinant …
Matched Description: … Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. ... Human erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues …

Calcifediol

The major circulating metabolite of vitamin D3 (cholecalciferol). It is produced in the liver and is the best indicator of the body's vitamin D stores. It is effective in the treatment of rickets and osteomalacia, both in azotemic and non-azotemic patients. Calcifediol also has mineralizing properties.
Approved
Nutraceutical
Matched Synonyms: … (3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-3,25-diol ... (5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-triene-3,25-diol …

Salmon calcitonin

Synthetic peptide, 32 residues long formulated as a nasal spray.
Approved
Investigational
Matched Synonyms: … Calcitonin salmon recombinant ... Recombinant salmon calcitonin …

Tibolone

Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha . Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic...
Approved
Investigational
Matched Synonyms: … 17-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-one …

Hepatitis B immune globulin

Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B. Infection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatitis-B vaccines are cancer-preventing vaccines. According to the Centers for Disease Control...
Approved
Investigational
Matched Synonyms: … Hepatitis B immune globulin human ... Hepatitis B immune globulin (human) ... Human hepatitis B immunoglobulin …
Matched Categories: … Human Immunoglobulin …

Axicabtagene ciloleucel

Axicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. The drug has a unique mechanism of action, as it utilizes the patient's own T cells, which play a central role in immune response to cancer. Once T-cells are collected from the patient, they are genetically engineered to express...
Approved
Matched Synonyms: … Autologous T cells transduced with retroviral vector encoding an anti-CD-19 CD28/CD3-zeta chimeric antigen …

Cholecystokinin

Cholecystokinin ( also known as CCK or CCK-PZ) is a peptide hormone of the gastrointestinal system which is responsible for stimulating the digestion of fat and protein. Cholecystokinin, previously called pancreozymin, is synthesized and secreted by enteroendocrine cells in the duodenum (the first portion of the small intestine) and leads...
Approved
Investigational
Matched Synonyms: … Human CCK-33 ... Human cholecystokinin-33 …

Prothrombin

Prothrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with acute major bleeding.
Approved
Matched Synonyms: … Coagulation factor II human ... Coagulation factor II (human) ... Human coagulation factor II …
Matched Description: … Prothrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation …

Natalizumab

Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it was withdrawn from the market following multiple reports of fatal progressive multifocal leukoencephalopathy (PML). In 2006, the FDA reintroduced the drug to the...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULFIDE WITH HUMAN-MOUSE ... IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULPHIDE WITH HUMAN-MOUSE …
Matched Description: … Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. …

Levonorgestrel

Levonorgestrel (LNG) is a synthetic progestogen similar to Progesterone used in contraception and hormone therapy.[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. Some of these devices...
Approved
Investigational
Matched Synonyms: … 17-Ethynyl-18-methyl-19-nortestosterone ... 17alpha-Ethynyl-18-homo-19-nortestosterone ... 17-alpha-Ethynyl-13-ethyl-19-nortestosterone …

Efbemalenograstim alfa

Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration.[L48852,A262167] As endogenous G-CSF mediates the differentiation of hematopoietic stem cells into granulocytes and eventually neutrophils, the administration of recombinant G-CSF like efbemalenograstim...
Approved
Matched Synonyms: … Recombinant dimeric g-csf fusion protein f627 …
Matched Description: … factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration ... Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating ... differentiation of hematopoietic stem cells into granulocytes and eventually neutrophils, the administration of recombinant …

Sotatercept

Sotatercept is an activin signalling inhibitor. It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension...
Approved
Investigational
Matched Synonyms: … (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN HEAVY CHAIN FC FRAGMENT), DIMER …
Matched Description: … It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin ... receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. …
Matched Categories: … Recombinant Proteins ... Recombinant Fusion Proteins …

Fecal microbiota

Fecal microbiota, given either as a rectal transplant or in an oral formulation of live spores, is an FDA-approved option to prevent the recurrence of Clostridioides difficile infection (CDI) in patients given an antibacterial treatment for recurrent CDI.[A259182,L46217,L46222] Although the incidence of CDI has declined and the number of cases...
Approved
Investigational
Matched Synonyms: … Donor human stool ... Donor human stool spores (ethanol treated) …
Matched Description: … Human fecal matter is then tested for a panel of transmissible pathogens and processed with methods aimed …

Plasma protein fraction (human)

The plasma protein fraction human (PPFh) is defined as a sterile solution of proteins composed mainly of albumin and globulin derived from human plasma. It is already reviewed under the category of biologics by the FDA where the processing, required tests, requirements and labeling are incorporated. This biologic should come...
Approved
Matched Synonyms: … Human plasma protein ... Human plasma proteins ... Human plasma protein fraction …
Matched Name: … Plasma protein fraction (human) …
Matched Description: … of albumin and globulin derived from human plasma. ... The plasma protein fraction human (PPFh) is defined as a sterile solution of proteins composed mainly ... [L2260] PPFh is a sterile, frozen solution of solvent/detergent treated human plasma. …
Matched Categories: … Human Serum Albumin …
Matched Products: … Plasma Protein Fraction (human) Protenate …

Pucotenlimab

Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. It received its first global approval in China in July 2022 for the treatment of solid tumours. It is being investigated in other cancers.
Approved
Investigational
Matched Synonyms: … Immunoglobulin g4 (252-theronine,306-proline,432-alanine), anti-(human programmed cell death 1) (human-mus ... musculus monoclonal hx008 .gamma.4-chain), disulfide with human-mus musculus monoclonal hx008 .kappa …
Matched Description: … Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. …

Rabies immune globulin, human

IMOGAM Rabies Pasteurized is indicated for post-exposure prophylaxis in persons suspected of exposure to rabies, who have not previously received a complete immunization regimen with a cell culture produced rabies vaccine. Persons previously vaccinated with other types of rabies vaccines in whom adequate antibody levels have not been demonstrated should...
Approved
Matched Synonyms: … Rabies immune globulin human ... Rabies immune globulin,human ... Rabies immune globulin (human) …
Matched Name: … Rabies immune globulin, human …
Matched Categories: … Human Rabies Immune Globulins …
Matched Products: … Hyperab Rabies Immune Globulin Human …

Human C1-esterase inhibitor

C1 Esterase Inhibitor (Human) is composed of purified endogenous complement component-1 esterase inhibitor (hC1INH) isolated from human plasma. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways.[L16586, L16606] This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE), a...
Approved
Matched Synonyms: … C1 inhibitor human ... C1 inhibitor (human) ... Human C1 inhibitor …
Matched Name: … Human C1-esterase inhibitor …
Matched Description: … (hC1INH) isolated from human plasma. ... C1 Esterase Inhibitor (Human) is composed of purified endogenous complement component-1 esterase inhibitor ... L16606] This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE), a human …
Matched Products: … HAEGARDA C1 Esterase Inhibitor Subcutaneous (Human) …

Tesamorelin

Tesamorelin is a stabilized synthetic peptide analogue of the hypothalamic peptide, Growth Hormone Releasing Hormone (GHRH) indicated for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy. Lipodystrophy is a metabolic condition characterized by insulin resistance, fat redistribution, and hyperlipidemia associated with antiretroviral therapy for HIV infection.
Approved
Investigational
Matched Synonyms: … N-[(3E)-1-oxo-3-hexenyl]Somatoliberin (human pancreatic islet) …

Albumin iodinated I-125 serum

I-125 iodinated albumin is a radiolabeled albumin-based diagnostic agent used in the determination of total blood and plasma volume.
Approved
Matched Synonyms: … Human albumin I-125 ... Human serum albumin I-125 ... Iodinated (125I) human serum albumin …

Albumin iodinated I-131 serum

Iodinated I-131 serum albumin is a radiopharmaceutical agent used for several diagnostic purposes, including the determination of body fluid volumes and the imaging of certain tissues.
Approved
Matched Synonyms: … Human albumin I-131 ... Human serum albumin I-131 ... Iodinated (131I) human serum albumin …

Cerliponase alfa

Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. It was the first FDA-approved treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and older with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl...
Approved
Investigational
Matched Synonyms: … Immature human tripeptidyl-peptidase 1 …

Protein S human

Protein S human is a vitamin K-dependent plasma glycoprotein which has antcoagulant properties . It serves as a negative feedback mechanism in the coagulation cascade.
Approved
Matched Synonyms: … Protein S (human) …
Matched Name: … Protein S human …
Matched Description: … Protein S human is a vitamin K-dependent plasma glycoprotein which has antcoagulant properties [A19561 …

Luteinizing hormone

Approved
Matched Synonyms: … Luteinising hormone (human) …

Human papillomavirus type 33 L1 capsid protein antigen

Human papillomavirus type 33 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 33. The vaccine is prepared from the purified...
Approved
Matched Synonyms: … Recombinant human papillomavirus type 33 L1 protein ... L1 protein, Human papillomavirus type 33 Vaccine …
Matched Name: … Human papillomavirus type 33 L1 capsid protein antigen …
Matched Description: … VLPs) of the major capsid (L1) protein of HPV Type 33 which are produced by separate fermentations in recombinant ... Human papillomavirus type 33 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular ... an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …

Human papillomavirus type 6 L1 capsid protein antigen

Human papillomavirus type 6 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Investigational
Matched Synonyms: … Recombinant human papillomavirus type 6 L1 protein ... L1 protein, Human papillomavirus type 6 Vaccine …
Matched Name: … Human papillomavirus type 6 L1 capsid protein antigen …
Matched Description: … Human papillomavirus type 6 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human ... capsid (L1) protein of HPV Types 6, 11, 16, and 18, which are produced by separate fermentations in recombinant ... an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Matched Categories: … Inactivated Human Papillomavirus Vaccine …
Displaying drugs 501 - 525 of 2733 in total