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Displaying drugs 526 - 550 of 2550 in total

Tofersen

Tofersen is under an intrathecally administered antisense oligonucleotide targeting the mutated SOD1 gene that causes amyotrophic lateral sclerosis (ALS). Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more than 200 SOD1 mutations documented.[A259028,A259033] Tofersen was granted accelerated approval from the FDA...
Approved
Investigational

Abrocitinib

Abrocitinib is an oral small-molecule inhibitor of Janus kinase 1 (JAK1). Janus kinases are intracellular enzymes involved in transduction pathways that regulate hematopoiesis and immune cell function. The Janus kinase (JAK)–signal transducer and activator of transcription (STAT) signalling pathway plays a central role in the pathogenesis of a variety of...
Approved
Investigational
Matched Description: … [A244549] Abrocitinib was approved by the European Commission on December 10, 2021, for the treatment …

Ganciclovir

An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Approved
Investigational
Matched Synonyms: … 2-(6-Amino-purin-9-ylmethoxy)-propane-1,3-diol ... 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine ... 9-((2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl)guanine …
Matched Iupac: … 2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-6,9-dihydro-1H-purin-6-one …

Calcium undecylenate

Approved
Experimental
Matched Synonyms: … Calcium 10-undecenoate ... Calcium diundec-10-enoate …
Matched Iupac: … calcium bis(undec-10-enoate) …
Matched Products: … Cruex Medicated Pwr 10% …

Adenosine

The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Synonyms: … 9-beta-D-Ribofuranosidoadenine ... 9-β-D-ribofuranosyl-9H-purin-6-amine ... 6-Amino-9-beta-D-ribofuranosyl-9H-purine …
Matched Iupac: … (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Mixtures name: … HydroGold 9 ... Neogen Code 9 Black Volume ... Neogen Code 9 Black Volume …
Matched Products: … ICEREN 10 ML 10 FLAKON ... Tissen NF 10 ... Tissen ICM 10 …

Streptococcus pneumoniae type 9v capsular polysaccharide antigen

Streptococcus pneumoniae type 9v capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 9v of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Mixtures name: … SII PNEUMOSIL Pneumococcal Polysaccharide Conjugate Vaccine (Adsorbed) (10-Valent) SUSPENSION FOR INJECTION ... SII PNEUMOSIL Pneumococcal Polysaccharide Conjugate Vaccine (Adsorbed) (10-Valent) SUSPENSION FOR INJECTION …

Technetium Tc-99m oxidronate

Technetium Tc-99m oxidronate, also known as 99mTc-methylene diphosphonate, is a radiopharmaceutical agent. A radiopharmaceutical is defined as a medicinal formulation containing radioisotopes that are used in major clinical areas for diagnosis and/or therapy. The radiopharmaceuticals based on technetium-99m are widely used for diagnostic purposes because 99mTc has a versatile chemistry...
Approved

Pemigatinib

Pemigatinib is a small molecule kinase inhibitor with antitumour activity. It works by inhibiting fibroblast growth factor receptors (FGFRs), which are receptor tyrosine kinases that activate signalling pathways in tumour cells. FGFRs gained attention as potential therapeutic targets in selected cancers, as FGFR gene alterations were observed in a wide...
Approved
Investigational

Perphenazine

An antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.
Approved
Matched Synonyms: … 4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol ... 2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol ... 4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol …
Matched Iupac: … 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethan-1-ol …
Matched Mixtures name: … โพลีบอน 4-10 ... Etrafon 2 10 …

Fluphenazine

A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Approved
Matched Synonyms: … 10-(3-(2-hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine ... 1-(2-hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazine ... 4-(3-(-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol …
Matched Iupac: … 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol …

alpha-Linolenic acid

Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition.
Approved
Investigational
Nutraceutical
Matched Synonyms: … 9-cis,12-cis,15-cis-octadecatrienoic acid …

Abacavir

Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. In vivo, abacavir sulfate dissociates to its free base, abacavir.
Approved
Investigational
Matched Synonyms: … {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol …
Matched Iupac: … [(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl]methanol …

Promazine

A phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. It is currently not approved for use in the United States.
Approved
Vet approved
Matched Synonyms: … 10-(3-(Dimethylamino)propyl)phenothiazine ... N,N-dimethyl-3-(10H-phenothiazin-10-yl)-propan-1-amine …
Matched Iupac: … dimethyl[3-(10H-phenothiazin-10-yl)propyl]amine …

Technetium Tc-99m sulfur colloid

Technetium 99m sulfur colloid is a radiopharmaceutical diagnostic agent used in the evaluation of various conditions including lymph node metastases in breast cancer, detection of shunt patency, imaging of reticuloendothelial cells for assessment of liver function, and studies of esophageal transit and gastroesophageal reflux. Following injection or oral administration, single...
Approved
Investigational

Technetium Tc-99m red blood cells

Technetium Tc-99m red blood cells is a radiopharmaceutical diagnostic agent that is intravenously administered to be used in blood pool imaging, including cardiac first pass and gated equilibrium imaging and for detection of sites of gastrointestinal bleeding. It is clinically useful in early detection and localization of bleeding sites, and...
Approved

Fluoxymesterone

An anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.
Approved
Illicit
Matched Synonyms: … 9-Fluoro-11β,17β-dihydroxy-17-methylandrost-4-en-3-one …

Idarubicin

An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Approved
Matched Iupac: … (7S,9S)-9-acetyl-7-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,9,11-trihydroxy-5,7,8,9,10,12 …
Matched Salts cas: … 57852-57-0 …
Matched Products: … ZAVEDOS CS INJECTION 10 mg/10 ml ... Idarubicin Accord 10 mg/10 ml Injektionslösung ... X 10 MG …

Methotrimeprazine

A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine. It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)
Approved
Investigational
Matched Synonyms: … (-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazine ... (-)-(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine …
Matched Iupac: … [(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-2-methylpropyl]dimethylamine …

Mesoridazine

A phenothiazine antipsychotic with effects similar to chlorpromazine.
Approved
Investigational
Matched Synonyms: … 10-(2-(1-Methyl-2-piperidyl)ethyl)-2-methylsulfinyl phenothiazine ... 10-(2(1-Methyl-2-piperidyl)ethyl)-2-(methylsulfinyl)phenothiazine ... 2-Methanesulfinyl-10-[2-(1-methyl-piperidin-2-yl)-ethyl]-10H-phenothiazine …
Matched Iupac: … 2-methanesulfinyl-10-[2-(1-methylpiperidin-2-yl)ethyl]-10H-phenothiazine …

Influenza A virus A/Brisbane/10/2010 live (attenuated) antigen

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … Influenza A virus A/Brisbane/10/2010 (H1N1) whole ... Influenza A virus A/Brisbane/10/2010 (H1N1) wild type …
Matched Name: … Influenza A virus A/Brisbane/10/2010 live (attenuated) antigen …

Scopolamine

Scopolamine is a tropane alkaloid isolated from members of the Solanaceae family of plants, similar to atropine and hyoscyamine, all of which structurally mimic the natural neurotransmitter acetylcholine.[A228423, A228763] Scopolamine was first synthesized in 1959, but to date, synthesis remains less efficient than extracting scopolamine from plants. As an acetylcholine...
Approved
Investigational
Matched Synonyms: … alpha-(Hydroxymethyl)benzeneacetic acid 9-methyl-3-oxa-9-azatricyclo(3.3.1.0(2.4))non-7-yl ester …
Matched Iupac: … (1R,2R,4S,5S,7S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0^{2,4}]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate …

Fluocinolone acetonide

Fluocinolone acetonide, with the formula 6-alpha, 9-alpha-difluoro-16-alpha, 17 alpha-acetonide, is a corticosteroid that presents a high lipophilicity. It has been used extensively in dermatological preparations and it has also been investigated thoroughly for its use in implantable corticosteroid devices. This type of device containing fluocinolone acetonide was developed by Taro...
Approved
Investigational
Vet approved
Matched Iupac: … {4,8}.0^{13,18}]icosa-14,17-dien-16-one ... 12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.0^{2,9}.0^ …
Matched Description: … Fluocinolone acetonide, with the formula 6-alpha, 9-alpha-difluoro-16-alpha, 17 alpha-acetonide, is a …

Epirubicin

An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Approved
Matched Synonyms: … 5,12-NAPHTHACENEDIONE, 10-((3-AMINO-2,3,6-TRIDEOXY-.ALPHA. ... (1S,3S)-3-GLYCOLOYL-1,2,3,4,6,11-HEXAHYDRO-3,5,12-TRIHYDROXY-10-METHOXY-6,11-DIOXO-1-NAPHTHACENYL 3-AMINO …
Matched Iupac: … (8S,10S)-10-{[(2R,4S,5R,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl …
Matched Products: … 4-EPEEDO-10 ... Farmorubicin 10 mg Stechampulle ... มัยซิน ชนิดฉีด (10 มก./5มล.) …

Buprenorphine

Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Iupac: … {1,6}.0^{6,14}.0^{7,12}]icosa-7,9,11-trien-11-ol ... cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-3-azahexacyclo[13.2.2.1^{2,8}.0^ …
Matched Salts cas: … 53152-21-9 …
Matched Products: … Butrans 10 ... BUPRE-HEXAL 7 T 10 UG/H ... BUTRANS 10 MIKROGRAMM/H …

Sebelipase alfa

The lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism of lipids, and its absence or deficiency results in the accumulation of lipids in various organs. This lipid accumulation can lead to end-organ damage in the form of liver dysfunction or malabsorption secondary...
Approved
Investigational
Displaying drugs 526 - 550 of 2550 in total