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Displaying drugs 526 - 550 of 2472 in total
Troplasminogen alfa is under investigation in clinical trial NCT00144014 (Safety and Efficacy Study in Acute Ischaemic Stroke).
Investigational
Matched Name: … Troplasminogen alfa
Matched Description: … Troplasminogen alfa is under investigation in clinical trial NCT00144014 (Safety and Efficacy Study in …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. It was approved by the FDA in 2014 for the treatment of Morquio syndrome. Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim™. The recommended dose is 2 mg per kg given intravenously over...
Approved
Investigational
Matched Synonyms: … Elosulfase alfa
Matched Name: … Elosulfase alfa
Matched Description: … Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim ... Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. …
Matched Categories: … elosulfase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Chondroitinases and Chondroitin Lyases …
Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. It is used to treat Respiratory Distress Syndrome (RDS) in premature infants with an endogenous pulmonary surfactant deficiency. Poractant alfa is an extract of natural porcine lung surfactant consisting of 99% polar lipids (mainly phospholipids)...
Approved
Matched Name: … Poractant alfa
Matched Description: … Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. ... and SP-C). ... phospholipids) and 1% hydrophobic low molecular weight proteins (surfactant associated proteins SP-B …
Antithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention of thromboembolic events in patients that have hereditary deficiency of antithrombin in high risk situations.
Approved
Investigational
Matched Synonyms: … Antithrombin Alfa
Matched Name: … Antithrombin Alfa
Matched Description: … Antithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention …
Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H)...
Approved
Investigational
Matched Synonyms: … Eftrenonacog alfa
Matched Name: … Eftrenonacog alfa
Matched Description: … Eftrenonacog alfa was developed and marketed as Alprolix for intravenous injection by Biogen. ... Eftrenonacog alfa acts as a replacement therapy to restore the levels of factor IX and allow normal hemostasis ... It was first approved by the FDA in March 2014 and later approved by the EMA in May 2016. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft.
Approved
Investigational
Withdrawn
Matched Synonyms: … Eptotermin alfa ... Eptotermina alfa
Matched Name: … Eptotermin alfa
Matched Description: … It is both a potent osteogenic factor and a specific regulator of nephrogenesis. ... Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... eptotermin alfa ... Drugs Affecting Bone Structure and Mineralization ... Intercellular Signaling Peptides and Proteins …
Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. It was the first FDA-approved treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and older with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl...
Approved
Investigational
Matched Synonyms: … Cerliponase alfa
Matched Name: … Cerliponase alfa
Matched Description: … treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and ... Cerliponase alfa was approved in April, 2017 (as Brineura). ... Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... cerliponase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
RO6874281 is under investigation in clinical trial NCT03193190 (A Study of Multiple Immunotherapy-based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-pancreatic Cancer)).
Investigational
Matched Name: … Simlukafusp alfa
Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin G Fc domain by way of a G4S linker. It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With Steroid Refractory Chronic Graft Versus Host Disease).
Investigational
Matched Synonyms: … Efavaleukin alfa
Matched Name: … Efavaleukin alfa
Matched Description: … It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With ... Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin …
Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy).
Investigational
Matched Synonyms: … Taldefgrobep alfa ... Talditercept alfa ... Immunoglobulin g1 (human fc fragment) fusion protein with peptide (synthetic 17-amino acid linker) fusion …
Matched Name: … Talditercept alfa
Matched Description: … Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy) ... Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the …
Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2 human interleukin 22 (IL-22) molecules linked to an immunoglobulin constant region (IgG2-Fc).[A225706, L27661] It is being developed by Evive Biotech (previously known as Generon BioMed Inc).
Investigational
Matched Name: … Eflepedocokin alfa
Matched Description: … Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Bucelipase alfa is under investigation in clinical trial NCT00743483 (Efficacy of Bucelipase Alfa (BSSL) in Patients With Cystic Fibrosis and Pancreatic Insufficiency).
Investigational
Matched Name: … Bucelipase alfa
Matched Description: … ) in Patients With Cystic Fibrosis and Pancreatic Insufficiency). ... Bucelipase alfa is under investigation in clinical trial NCT00743483 (Efficacy of Bucelipase Alfa (BSSL …
Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as Sanfilippo syndrome B.
Investigational
Matched Synonyms: … Tralesinidase alfa
Matched Name: … Tralesinidase alfa
Matched Description: … Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Intercellular Signaling Peptides and Proteins …
Investigational
Matched Name: … Alidornase alfa
Investigational
Matched Name: … Nemvaleukin alfa
Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic hybrid Fc fragment. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Synonyms: … Eftansomatropin alfa
Matched Name: … Eftansomatropin alfa
Matched Description: … Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Lusacomfar Alfa is a recombinant complement factor H
Investigational
Matched Name: … Lusacomfar Alfa
Matched Description: … Lusacomfar Alfa is a recombinant complement factor H …
Zelpultide alfa is a recombinant human surfactant protein D.
Investigational
Matched Synonyms: … PROTEIN D), NON-COVALENT QUADRUPLE TRIMER, PRODUCED IN HUMAN MYELOGENOUS LEUKEMIA K562 CELLS, GLYCOFORME ALFA
Matched Name: … Zelpultide alfa
Matched Description: … Zelpultide alfa is a recombinant human surfactant protein D. …
Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration.[L48852,A262167] As endogenous G-CSF mediates the differentiation of hematopoietic stem cells into granulocytes and eventually neutrophils, the administration of recombinant G-CSF like efbemalenograstim...
Approved
Matched Name: … Efbemalenograstim alfa
Matched Description: … the production of neutrophils and thus reducing the severity and duration of neutropenia. ... GC-627-05 in the US and Europe respectively. ... A262167] As endogenous G-CSF mediates the differentiation of hematopoietic stem cells into granulocytes and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... efbemalenograstim alfa
Natural interferon alpha or Multiferon is obtained from the leukocyte fraction of human blood following induction with Sendai virus. Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography. Interferon alpha proteins are mainly involved in innate immune response against viral infection. They come in 13...
Investigational
Matched Synonyms: … Interferon alfa
Matched Name: … Interferon alfa
Matched Description: … Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography ... Of these, IFN-α2 and IFN-α14 are glycosylated. ... Multiferon consists of the 6 major subtypes are IFN-α1, IFN-α2, IFN-α8, IFN-α10, IFN-α14 and IFN-α21. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive.
Approved
Vet approved
Matched Synonyms: … Edetic acid ... Acido edetico ... Acide edetique …
Matched Name: … Edetic acid
Matched Iupac: … 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetic acid
Matched Description: … It is used in pharmaceutical manufacturing and as a food additive. …
Matched Categories: … Diet, Food, and Nutrition ... Acids, Acyclic ... Carboxylic Acids
Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).
Investigational
Matched Synonyms: … Antagonist of the endosomal Toll-like receptors (TLRs) 7, 8, and 9 …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Tienilic acid, or ticrynafen, is a diuretic drug with uric acid-lowering action which was marketed for the treatment of hypertension. It was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and hepatitis. (Manier et al., 1982)
Withdrawn
Matched Synonyms: … Tienilic acid ... Thienylic acid ... Acide tiénilique …
Matched Name: … Tienilic acid
Matched Iupac: … 2-[2,3-dichloro-4-(thiophene-2-carbonyl)phenoxy]acetic acid
Matched Description: … It was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and ... Tienilic acid, or ticrynafen, is a diuretic drug with uric acid-lowering action which was marketed for …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Hydroxy Acids ... tienilic acid ... Aryloxyacetic Acid Derivatives …
Stearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty acids that comes from many animal and vegetable fats and oils. It is a waxy solid.
Approved
Experimental
Matched Synonyms: … Acide stéarique ... Stearic acid ... Octadecoic acid
Matched Name: … Stearic acid
Matched Iupac: … octadecanoic acid
Matched Description: … acids that comes from many animal and vegetable fats and oils. ... Stearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty …
Matched Categories: … Fatty Acids ... Stearic Acids
Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. Being unstable in the pure form, hypochlorite is most commonly used for bleaching, disinfectation, and water treatment purposes in its salt form, sodium hypochlorite. Hypochlorite is often used as a chemical reagent for chlorination and oxidation...
Approved
Matched Description: … Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. ... Hypochlorite is often used as a chemical reagent for chlorination and oxidation reactions. ... Being unstable in the pure form, hypochlorite is most commonly used for bleaching, disinfectation, and
Matched Categories: … Antiseptics and Disinfectants ... Acids ... Acids, Noncarboxylic …
Matched Products: … SUPERCLEAN Micro Acid Hypochlorite Disinfectant …
Displaying drugs 526 - 550 of 2472 in total