Displaying drugs 526 - 550 of 14095 in total
Bordetella pertussis pertactin antigen (formaldehyde inactivated)
Approved
Matched Mixtures name: … Repevax Injektionssuspension in einer Fertigspritze …
Haemagglutinin-strain A(H3N2)
Approved
Matched Mixtures name: … Afluria Tetra Injektionssuspension in einer Fertigspritze …
Tolazamide
A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Approved
Investigational
Matched Description: … A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide. …
Matched Categories: … Drugs Used in Diabetes ... combinations of sulfonamides …
Matched Categories: … Drugs Used in Diabetes ... combinations of sulfonamides …
Mechlorethamine
A vesicant and necrotizing irritant destructive to mucous membranes, mechlorethamine is an alkylating drug. It was formerly used as a war gas. The hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. It causes severe gastrointestinal and bone marrow damage.
The FDA granted marketing approval for the orphan...
Approved
Investigational
Matched Synonyms: … bis(2-chloroethyl)methylamine ... methylbis(2-chloroethyl)amine ... N-methyl-bis(2-chloroethyl)amine …
Matched Iupac: … bis(2-chloroethyl)(methyl)amine …
Matched Description: … Each tube of Valchlor contains 0.016% of mechlorethamine which is equivalent to 0.02% mechlorethamine ... The hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. ... stage IA and IB mycosis fungoides-type cutaneous T-cell lymphoma (CTCL) in patients who have received …
Matched Categories: … Weapons of Mass Destruction ... Compounds used in a research, industrial, or household setting …
Matched Iupac: … bis(2-chloroethyl)(methyl)amine …
Matched Description: … Each tube of Valchlor contains 0.016% of mechlorethamine which is equivalent to 0.02% mechlorethamine ... The hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. ... stage IA and IB mycosis fungoides-type cutaneous T-cell lymphoma (CTCL) in patients who have received …
Matched Categories: … Weapons of Mass Destruction ... Compounds used in a research, industrial, or household setting …
Clavulanic acid
Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with Amoxicillin or Ticarcillin to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infections. Clavulanic acid is derived from the organism Streptomyces clavuligerus. When it is combined with amoxicillin, clavulanic acid is...
Approved
Vet approved
Matched Synonyms: … (Z)-(2R,5R)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid …
Matched Iupac: … (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Dioxybenzone
Dioxybenzone, or benzophenone-8, is an organic compound derived from DB01878 that is used as a sunscreen agent. It absorbed UV-B and UV-AII rays. Dioxybenzone is an approved sunscreen ingredient in concentrations up to 3% .
Approved
Matched Iupac: … 2-(2-hydroxybenzoyl)-5-methoxyphenol …
Matched Description: … Dioxybenzone is an approved sunscreen ingredient in concentrations up to 3% [L2525]. …
Matched Description: … Dioxybenzone is an approved sunscreen ingredient in concentrations up to 3% [L2525]. …
Tazobactam
Tazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. It is combined with Piperacillin and Ceftolozane for the treatment of a variety of bacterial infections.
Piperacillin-tazobactam was initially approved by the FDA in 1994, and ceftolozane-tazobactam was approved...
Approved
Matched Iupac: … 5R)-3-methyl-4,4,7-trioxo-3-[(1H-1,2,3-triazol-1-yl)methyl]-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2- …
Matched Description: … mortality in hospitalized patients. ... Tazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other ... It is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections …
Matched Salts cas: … 89785-84-2 …
Matched Mixtures name: … Zosyn in Galaxy Containers ... Zosyn in Galaxy Containers ... Zosyn in Galaxy Containers …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … mortality in hospitalized patients. ... Tazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other ... It is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections …
Matched Salts cas: … 89785-84-2 …
Matched Mixtures name: … Zosyn in Galaxy Containers ... Zosyn in Galaxy Containers ... Zosyn in Galaxy Containers …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Levocarnitine
Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Approved
Investigational
Matched Synonyms: … 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner salt …
Matched Description: … It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias ... Constituent of striated muscle and liver. …
Matched Products: … TEFECTUS 2 G/10 ML ORAL ÇÖZELTİ, 10 ADET ... T-KARNIT 2 G/10 ML ORAL ÇÖZELTI IÇEREN FLAKON, 10 ADET ... METACARTIN 2 G/10 ML ORAL ÇÖZELTI IÇEREN FLAKON ,10 FLAKON …
Matched Description: … It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias ... Constituent of striated muscle and liver. …
Matched Products: … TEFECTUS 2 G/10 ML ORAL ÇÖZELTİ, 10 ADET ... T-KARNIT 2 G/10 ML ORAL ÇÖZELTI IÇEREN FLAKON, 10 ADET ... METACARTIN 2 G/10 ML ORAL ÇÖZELTI IÇEREN FLAKON ,10 FLAKON …
Tropisetron
Tropisetron is an indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting.
Tropisetron appears to be well tolerated with the most frequently reported adverse effect being headache. Extrapyramidal...
Approved
Investigational
Matched Description: … at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting ... As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin …
Matched Salts cas: … 833482-77-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 833482-77-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Pitolisant
Pitolisant is a selective antagonist or inverse agonist of the histamine H3 receptor used to treat type 1 or 2 narcolepsy. Narcolepsy is a chronic neurological disorder that affects 1 in 2,000 individuals and is characterized by excessive daytime sleepiness, abnormal REM sleep manifestations, sleep paralysis and hypnagogic hallucinations. About...
Approved
Investigational
Matched Description: … 1 or 2 narcolepsy. ... the signalling of other neurotransmitters in the brain. ... In a European clinical trial of adult patients with narcolepsy, there was a reduction in the Epworth …
Sacituzumab govitecan
Metastatic triple-negative breast cancer (mTNBC) is an aggressive form of breast cancer with limited treatment options involving cytotoxic chemotherapy agents. Targeted chemotherapy through the application of antibody-conjugated agents (ADCs) is a recent advance in cancer treatment. One such ADC is sacituzumab govitecan, which combines a humanized anti-trophoblast cell-surface antigen 2...
Approved
Investigational
Matched Description: … advance in cancer treatment. ... (TROP-2) antibody with the topoisomerase I inhibitor SN-38. ... such ADC is sacituzumab govitecan, which combines a humanized anti-trophoblast cell-surface antigen 2 …
Matched Categories: … Trop-2-Directed Monoclonal Antibodies …
Matched Categories: … Trop-2-Directed Monoclonal Antibodies …
Cilazapril
Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. It belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. It is branded as Inhibace in Canada and...
Approved
Matched Iupac: … (1S,9S)-9-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-10-oxo-octahydro-1H-pyridazino[1,2-a][1,2]diazepine …
Matched Description: … None of these varieties are available in the United States. ... It is branded as Inhibace in Canada and other countries, Vascace and Dynorm in a number of European countries ... Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. …
Matched Salts cas: … 92077-78-6 …
Matched Description: … None of these varieties are available in the United States. ... It is branded as Inhibace in Canada and other countries, Vascace and Dynorm in a number of European countries ... Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. …
Matched Salts cas: … 92077-78-6 …
Thallous chloride Tl-201
Approved
Sulfathiazole
Sulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide.
Except for those formulated for vaginal use, the FDA withdrew its approval for the use of...
Approved
Vet approved
Withdrawn
Matched Synonyms: … 2-Sulfonamidothiazole ... 2-Sulfanilamidothiazol ... 2-Sulfanilamidothiazole …
Matched Iupac: … 4-amino-N-(1,3-thiazol-2-yl)benzene-1-sulfonamide …
Matched Description: … It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide. ... Except for those formulated for vaginal use, the FDA withdrew its approval for the use of all drug products …
Matched Categories: … combinations of sulfonamides …
Matched Iupac: … 4-amino-N-(1,3-thiazol-2-yl)benzene-1-sulfonamide …
Matched Description: … It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide. ... Except for those formulated for vaginal use, the FDA withdrew its approval for the use of all drug products …
Matched Categories: … combinations of sulfonamides …
Remestemcel-L
Remestemcel-L is a third-party, off-the-shelf suspension of ex-vivo cultured adult human mesenchymal stem cells intended for intravenous infusion. The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen (HLA)–unmatched healthy adult donors and have the ability to differentiate into different tissue cells. It was...
Approved
Investigational
Matched Description: … It was approved for use in Canada in May 2012 as Prochymal for the management of refractory acute Graft ... In clinical studies, patients treated with remestemcel-L demonstrated an improvement in their aGvHD and ... in a risk for poor outcomes and creating a significant clinical challenge [A31818]. …
Bromocriptine
Bromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity. It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia. Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as well as the treatment of acromegaly. Bromocriptine has been...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-bromo-α-ergokryptin ... 2-bromo-α-ergocryptine ... 2-Bromo-alpha-ergocryptine …
Matched Iupac: … [7.3.0.0^{2,6}]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14 ... (4R,7R)-10-bromo-N-[(1S,2S,4R,7S)-2-hydroxy-7-(2-methylpropyl)-5,8-dioxo-4-(propan-2-yl)-3-oxa-6,9-diazatricyclo …
Matched Description: … In 1995, the FDA withdrew the approval of bromocriptine mesylate for the prevention of physiological ... somatotropin (growth hormone) secretion in some patients with acromegaly. ... Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as …
Matched Categories: … Adrenergic alpha-2 Receptor Agonists …
Matched Iupac: … [7.3.0.0^{2,6}]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14 ... (4R,7R)-10-bromo-N-[(1S,2S,4R,7S)-2-hydroxy-7-(2-methylpropyl)-5,8-dioxo-4-(propan-2-yl)-3-oxa-6,9-diazatricyclo …
Matched Description: … In 1995, the FDA withdrew the approval of bromocriptine mesylate for the prevention of physiological ... somatotropin (growth hormone) secretion in some patients with acromegaly. ... Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as …
Matched Categories: … Adrenergic alpha-2 Receptor Agonists …
Bezafibrate
Antilipemic agent that lowers cholesterol and triglycerides. It decreases low density lipoproteins and increases high density lipoproteins.
Approved
Investigational
Matched Synonyms: … 2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid …
Matched Iupac: … 2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-2-methylpropanoic acid …
Matched Iupac: … 2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-2-methylpropanoic acid …
Chlorzoxazone
A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
Approved
Matched Synonyms: … 5-chloro-2-benzoxazolol ... 5-chloro-2-benzoxazolone ... 5-chloro-2-benzoxazolinone …
Matched Iupac: … 5-chloro-2,3-dihydro-1,3-benzoxazol-2-one …
Matched Description: … and subcortical areas of the brain. ... It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 5-chloro-2,3-dihydro-1,3-benzoxazol-2-one …
Matched Description: … and subcortical areas of the brain. ... It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Glutethimide
Glutethimide is a hypnotic and sedative. Its use has been largely superseded by other drugs.
Approved
Illicit
Matched Synonyms: … 2-Ethyl-2-phenylglutarimide …
Rilonacept
Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein linked to the Fc portion of immunoglobulin G1. Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome...
Approved
Investigational
Matched Description: … Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as ... Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein ... syndromes, including familial cold auto-inflammatory syndrome (FCAS) and Muckle-Wells Syndrome (MWS), in …
Thiopental
A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure. It does not...
Approved
Vet approved
Matched Synonyms: … 2-Thio-5-ethyl-5-sec-pentylbarbituric acid ... 5-Ethyl-5-(1-methyl-butyl)-2-thioxo-dihydro-pyrimidine-4,6-dione …
Matched Iupac: … 5-ethyl-5-(pentan-2-yl)-2-sulfanylidene-1,3-diazinane-4,6-dione …
Matched Description: … It has been used in neurosurgical patients to reduce increased intracranial pressure. ... of complete anesthesia of short duration. ... It is also used for hypnosis and for the control of convulsive states. …
Matched Categories: … combinations of barbiturates …
Matched Iupac: … 5-ethyl-5-(pentan-2-yl)-2-sulfanylidene-1,3-diazinane-4,6-dione …
Matched Description: … It has been used in neurosurgical patients to reduce increased intracranial pressure. ... of complete anesthesia of short duration. ... It is also used for hypnosis and for the control of convulsive states. …
Matched Categories: … combinations of barbiturates …
Drotaverine
Drotaverine is an antispasmodic drug that works by inhibiting phosphodiesterase-4 (PDE4). It is a benzylisoquinoline derivative that is structurally related to papaverine, although it displays more potent antispasmodic activities than papaverine. Drotaverine has been used in the symptomatic treatment of various spastic conditions, such as gastrointestinal diseases, biliary dyskinesia, and...
Approved
Investigational
Matched Description: … [A7036] It also has been investigated in dysmenorrhea, abortion, [A231609] and augmentation of labour ... [A231614] More recently, drotaverine gained attention in the treatment of benign prostatic hyperplasia ... Drotaverine has been used in the symptomatic treatment of various spastic conditions, such as gastrointestinal …
Matched Salts cas: … 985-12-6 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 985-12-6 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Cyanocobalamin Co-60
Cyanocobalamin Co-60 is an analog of Vitamin B12 labeled with Co60. Cyanocobalamin Co-60 was used for the diagnosis of pernicious anemia, but now it is withdrawn from the market in the US for unknown reasons.
Approved
Withdrawn
Matched Iupac: … )-18-(2-{[(2R)-2-{[(2R,3S,4R,5S)-5-(5,6-dimethyl-1H-1,3-benzodiazol-1-yl)-4-hydroxy-2-(hydroxymethyl) ... (60Co)cobalt(3+) (2R,3S,4S,6Z,8S,9S,11Z,14S,16Z,18R,19R)-4,9,14-tris(2-carbamoylethyl)-3,8,19-tris(carbamoylmethyl …
Matched Description: … market in the US for unknown reasons. ... Cyanocobalamin Co-60 is an analog of Vitamin B12 labeled with Co60. ... Cyanocobalamin Co-60 was used for the diagnosis of pernicious anemia, but now it is withdrawn from the …
Matched Description: … market in the US for unknown reasons. ... Cyanocobalamin Co-60 is an analog of Vitamin B12 labeled with Co60. ... Cyanocobalamin Co-60 was used for the diagnosis of pernicious anemia, but now it is withdrawn from the …
Mifamurtide
Mifamurtide is an immunomodulator with antitumor activity via activation of macrophages and monocytes. Also called L-MTP-PE, mifamurtide may be a liposomal form of of the active ingredient MTP-PE, which is a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP). MDP is a motif present in all gram-positive and...
Approved
Experimental
Matched Iupac: … sodium (2R)-1-({2-[(2S)-2-[(4R)-4-carbamoyl-4-[(2S)-2-[(2R)-2-{[(2R,3R,4R,5R)-2-acetamido-4,5,6-trihydroxy ... yl]oxy}propanamido]propanamido]butanamido]propanamido]ethyl phosphono}oxy)-3-(hexadecanoyloxy)propan-2- …
Matched Description: … In a large, randomized, open-label, multicenter, phase III trial, the treatment of mifamurtide in conjunction ... Osteosarcoma is the most common primary malignant bone tumor that usually arises in the metaphyses of ... In the US, it is currently under investigation that holds orphan drug status for the treatment of osteosarcoma …
Matched Description: … In a large, randomized, open-label, multicenter, phase III trial, the treatment of mifamurtide in conjunction ... Osteosarcoma is the most common primary malignant bone tumor that usually arises in the metaphyses of ... In the US, it is currently under investigation that holds orphan drug status for the treatment of osteosarcoma …
Elbasvir
Elbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, an infectious liver disease caused by infection with hepatitis C virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in...
Approved
Matched Iupac: … methyl N-[(2S)-1-[(2S)-2-{5-[(9S)-14-{2-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl]pyrrolidin ... -2-yl]-1H-imidazol-5-yl}-9-phenyl-8-oxa-10-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-1(17),2(7) ... ,3,5,11(16),12,14-heptaen-5-yl]-1H-imidazol-2-yl}pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate …
Matched Description: … to validate elbasvir as a potential therapy against SARS-CoV-2. ... Approved in January 2016 by the FDA, Zepatier is indicated for the treatment of HCV genotypes 1 and 4 ... SARS-CoV-2, the human coronavirus responsible for the COVID-19 pandemic. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antivirals for treatment of HCV infections …
Matched Description: … to validate elbasvir as a potential therapy against SARS-CoV-2. ... Approved in January 2016 by the FDA, Zepatier is indicated for the treatment of HCV genotypes 1 and 4 ... SARS-CoV-2, the human coronavirus responsible for the COVID-19 pandemic. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antivirals for treatment of HCV infections …
Displaying drugs 526 - 550 of 14095 in total