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Displaying drugs 526 - 550 of 2345 in total
Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine. It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's Specramast LC (lactating cow formula) product. It is resistant to hydrolysis by beta-lactamase, and has activity...
Vet approved
Matched Synonyms: … Ceftiofur crystalline free acid
Matched Iupac: … acetamido]-3-[(furan-2-carbonylsulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Description: … It is resistant to hydrolysis by beta-lactamase, and has activity against both Gram-positive and Gram-negative ... Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary ... It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's …
Experimental
Matched Synonyms: … 4-amino-3-phenylbutyric acid
Matched Iupac: … 4-amino-3-phenylbutanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids ... Hypnotics and Sedatives …
Agatolimod is under investigation in clinical trial NCT00471471 (Vaccine Therapy in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery).
Investigational
Matched Synonyms: … PF-3512676 free acid
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Florilglutamic acid F-18 is under investigation in clinical trial NCT02370563 (PET Imaging of Intracranial Cancers With 18F-FSPG).
Investigational
Matched Synonyms: … [F18] Florilglutamic Acid
Matched Name: … Florilglutamic acid F-18 …
Matched Iupac: … (2S,4S)-2-amino-4-[3-(¹⁸F)fluoropropyl]pentanedioic acid
Matched Description: … Florilglutamic acid F-18 is under investigation in clinical trial NCT02370563 (PET Imaging of Intracranial …
Foslinanib is under investigation in clinical trial NCT03600233 (Study of CVM-1118 for Patients With Advanced Neuroendocrine Tumors).
Investigational
Matched Synonyms: … Trx-818 free acid
Matched Iupac: … {[2-(3-fluorophenyl)-6-methoxy-4-oxo-1,4-dihydroquinolin-5-yl]oxy}phosphonic acid
Imidazole-4-carboxylic acid is under investigation in clinical trial NCT00583895 (Safety and Efficacy Study of Imcooh Cream in Patients Suffering From Moderate Atopic Dermatitis).
Investigational
Matched Synonyms: … 4-Imidazolecarboxylic acid
Matched Name: … Imidazole-4-carboxylic acid
Matched Iupac: … 1H-imidazole-4-carboxylic acid
Matched Description: … Imidazole-4-carboxylic acid is under investigation in clinical trial NCT00583895 (Safety and Efficacy …
Nedosiran is an RNA interference targeting hepatic lactate dehydrogenase, the enzyme responsible for the conversion of glyoxylate to oxalate. Oxalate, particularly calcium oxalate, precipitation is the main cause of kidney stones formation; therefore, blocking the production of oxalate can help alleviate renal symptoms. Nedosiran was approved by the FDA on...
Approved
Investigational
Matched Synonyms: … DCR-PHXC free acid
Matched Description: … older and adults with primary hyperoxaluria type 1 (PH1) and relatively preserved kidney function. ... sup>, 2023, under the brand name RIVFLOZA to lower urinary oxalate levels in children 9 years of age and ... This approval is based on the favorable results from the pivotal phase 2 PHYOXTM2 and interim …
Experimental
Matched Synonyms: … Methyl ester nonanoic acid ... Pelargonic acid methyl ester …
Lonidamine (LND) is a drug that interferes with energy metabolism of cancer cells, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK). In such way LND could impair energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and by some cytotoxic drugs.
Investigational
Matched Synonyms: … diclondazolic acid ... 1-(2,4-dichlorbenzyl)-indazole-3-carboxylic acid
Matched Iupac: … 1-[(2,4-dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid
Matched Description: … energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Investigational
Matched Synonyms: … Isonicotinic acid (2-(carboxymethoxy)benzylidene)hydrazide ... Isonicotinic acid (o-(carboxymethoxy)benzylidene)hydrazide …
Matched Iupac: … 2-{2-[(E)-{[(pyridin-4-yl)formamido]imino}methyl]phenoxy}acetic acid
Matched Categories: … Acids, Heterocyclic ... Isonicotinic Acids
Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from arginine. L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine.
Approved
Nutraceutical
Matched Synonyms: … (S)-2,5-Diaminopentanoic acid ... (S)-2,5-diaminovaleric acid ... (S)-α,δ-diaminovaleric acid
Matched Iupac: … (2S)-2,5-diaminopentanoic acid
Matched Description: … Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from ... L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine …
Matched Mixtures name: … PRIMENE 10% AMINO ACID INTRAVENOUS INFUSION …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino ... Bile and Liver Therapy …
The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
Approved
Investigational
Matched Synonyms: … Probenecid acid ... 4-((Dipropylamino)sulfonyl)benzoic acid ... p-(Dipropylsulfamoyl)benzoic acid
Matched Iupac: … 4-(dipropylsulfamoyl)benzoic acid
Matched Description: … It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. ... Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal …
Matched Mixtures name: … Probenecid and Colchicine ... Probenecid and Colchicine ... Probenecid and Colchicine …
Matched Categories: … Preparations Increasing Uric Acid Excretion ... Preparations With No Effect on Uric Acid Metabolism ... colchicine and probenecid ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Experimental
Matched Synonyms: … 2-Amino-6-hydroxycaproic acid ... alpha-Amino-epsilon-hydroxycaproic acid
Matched Iupac: … (2S)-2-amino-6-hydroxyhexanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Eprodisate slows the decline of renal function in AA amyloidosis.
Investigational
Matched Synonyms: … 1,3-propanedisulfonic acid ... Propane-1,3-disulfonic acid
Matched Iupac: … propane-1,3-disulfonic acid
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Monoctanoin is used to dissolve cholesterol gallstones.
Experimental
Matched Synonyms: … Caprylic acid α-monoglyceride ... Octanoic acid 1-monoglyceride …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids
Experimental
Matched Synonyms: … Glutamic acid alpha-amide ... L-Glutamic acid alpha-amide …
Matched Iupac: … (4S)-4-amino-4-carbamoylbutanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino ... Amino Acids, Neutral …
Experimental
Matched Synonyms: … (3R)-3-methyl-L-glutamic acid ... (2S,3R)-2-azanyl-3-methyl-pentanedioic acid
Matched Name: … 3-Methylglutamic acid
Matched Iupac: … (2S,3R)-2-amino-3-methylpentanedioic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic ... Excitatory Amino Acids
Investigational
Matched Synonyms: … 4-(2-Hydroxyethyl)-1-piperazineethane sulfonic acid ... 4-(2-Hydroxyethyl)-1-piperazineethane sulphonic acid
Matched Iupac: … 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethane-1-sulfonic acid
Matched Categories: … Alkanesulfonic Acids ... Sulfur Acids ... Sulfonic Acids
Dimethyl fumarate is an agent indicated for the treatment of relapsing forms of multiple sclerosis.[A253942,L43752] The mechanism of action of dimethyl fumarate in multiple sclerosis is not well understood. It is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor...
Approved
Investigational
Matched Synonyms: … Fumaric acid, dimethyl ester ... (E)-But-2-enedioic acid dimethyl ester ... trans-Butenedioic acid dimethyl ester …
Matched Description: … agent for multiple sclerosis approved by the FDA, following [fingolimod] and [teriflunomide]. ... [L43752] Dimethyl fumarate is marketed under the brand name Tecfidera, and it was the third oral disease-modifying …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids
Investigational
Matched Synonyms: … Hypothiocyanite and lactoferrin …
TPMPA ((1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid) is a selective antagonist of GABAC receptors (also known as GABA-ρ or GABAA-ρ receptors). GABAC receptors are found primarily in the retina, although they may be present in other tissues, including the hippocampus, spinal cord, superior colliculus, pituitary and the gut.[A245308,A245313] TPMPA is used as a pharmacological...
Experimental
Matched Synonyms: … (1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid ... P-Methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)phosphinic acid ... Phosphinic acid, P-methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)- …
Matched Iupac: … methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid
Matched Description: … TPMPA ((1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid) is a selective antagonist of GABA ... be present in other tissues, including the hippocampus, spinal cord, superior colliculus, pituitary and
EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2).
Investigational
Matched Synonyms: … Autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the HBG1 and HBG2 ... ) at the HBG1 and HBG2 promoters ... autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/Cas12a ribonucleoprotein (RNP …
Matched Description: … cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2). ... EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor …
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Synonyms: … 2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid ... 4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid ... 4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid
Matched Iupac: … 4-chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid
Matched Description: … It is an anthranilic acid derivative. ... Furosemide has a fast onset and short duration of action and has been used safely and effectively in ... both pediatric and adult patients. …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... furosemide and potassium ... furosemide and potassium-sparing agents ... High-Ceiling Diuretics and Potassium-Sparing Agents …
Experimental
Matched Products: … Lacto Pack D29 Cream Care …
Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (also known as deep partial-thickness burns). It was developed as an alternative to autografting...
Approved
Matched Synonyms: … Viable and metabolically active allogeneic human NIKS keratinocytes and human dermal fibroblasts cellularized ... allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat …
Matched Name: … Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen …
Matched Description: … active and viable cells, provide a variety of human growth factors and cytokines as well as extracellular ... Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an ... developed as an alternative to autografting - the process by which a patient's own skin is harvested and
Displaying drugs 526 - 550 of 2345 in total