Displaying drugs 5476 - 5500 of 11638 in total
Ditazole
Ditazole is a non-steroidal anti-inflammatory drug (NSAID). Ditazole's analgesic and antipyretic effects are similar to phenylbutazone. Additionally, ditazole is a platelet aggregation inhibitor marketed in Spain and Portugal with trade name Ageroplas.
Experimental
Withdrawn
Matched Description: … Ditazole is a non-steroidal anti-inflammatory drug (NSAID). ... Additionally, ditazole is a platelet aggregation inhibitor marketed in Spain and Portugal with trade …
Methaqualone
Methaqualone is a sedative-hypnotic drug that is similar in effect to barbiturates, a general central nervous system depressant. The sedative-hypnotic activity was first noted by Indian researchers in the 1950s and in 1962 methaqualone itself was patented in the US by Wallace and Tiernan. Its use peaked in the early...
Illicit
Withdrawn
Matched Description: … Methaqualone is a sedative-hypnotic drug that is similar in effect to barbiturates, a general central ... It has also been used illegally as a recreational drug, commonly known as Quaaludes, Sopors, Ludes or ... Its use peaked in the early 1970s as a hypnotic, sedative, and muscle relaxant commonly used for insomnia …
AER001
AER001, an IL4/13 receptor antagonist for severe asthma and eczema currently in Phase 2 studies.
Investigational
Apoptone
Investigational
Skin-derived ABCB5-positive Mesenchymal Stem cells
Skin-derived ABCB5-positive Mesenchymal Stem cells are under investigation in clinical trial NCT04971161 (Allogeneic Abcb5-positive Dermal Mesenchymal Stromal Cells for Treatment of CVU (Phase Iib)).
Investigational
Acepromazine
Acepromazine is one of the phenothiazine derivative psychotropic drugs, used little in humans, however frequently in animals as a sedative and antiemetic.
Experimental
Vet approved
Matched Description: … phenothiazine derivative psychotropic drugs, used little in humans, however frequently in animals as a …
Sotrastaurin
Sotrastaurin has been used in trials studying the basic science and treatment of Uveal Melanoma, Richter Syndrome, Prolymphocytic Leukemia, Recurrent Mantle Cell Lymphoma, and Recurrent Small Lymphocytic Lymphoma, among others.
Investigational
Amidephrine
Experimental
Tolrestat
Tolrestat (INN) (AY-27773) is an aldose reductase inhibitor which was approved for the control of certain diabetic complications. While it was approved for marketed in several countries, it failed a Phase III trial in the U.S. due to toxicity and never received FDA approval. It was sold under the tradename...
Withdrawn
Matched Description: … While it was approved for marketed in several countries, it failed a Phase III trial in the U.S. due …
Archexin
Investigational
Enclomiphene
Investigational
Tengonermin
Tengonermin, also known as NGR-hTNF, is a vascular-targeting drug. It is a recombinant protein and peptide-targeted agent consisting of the human Tumour Necrosis Factor-α (TNF-α) conjugated with the CNGRCG peptide. This drug works by modifying the tumor microenvironment and increasing intratumoral chemotherapy penetration and T-cell infiltration. NGR-hTNF specifically targets angiogenic...
Investigational
Matched Description: … Tengonermin, also known as NGR-hTNF, is a vascular-targeting drug. ... [A233265] It is a recombinant protein and peptide-targeted agent consisting of the human Tumour Necrosis ... [A233270] A study also demonstrated that binding of the NGR-motif to CD13 determined both the homing …
Roquinimex
Roquinimex is a derivative of quinoline that presents immunostimulant properties. Its effects are suggested to increase the activity of NK cells and macrophage cytotoxicity. Additionally, roquinimex is known to inhibit angiogenesis and to decrease the synthesis of TNF alpha.
Investigational
Matched Description: … Roquinimex is a derivative of quinoline that presents immunostimulant properties. …
Arsenous acid
Experimental
Investigational
Abscisic Acid
Investigational
Methane
Experimental
Aminopentamide
Experimental
Vet approved
ANX-510
ANX-510 (CoFactor) is a folate-based biomodulator drug being developed to enhance the activity and reduce associated toxicity of the widely used cancer chemotherapy, 5-fluorouracil (5-FU). CoFactor use with 5-FU is being evaluated in clinical trials in first line treatment of metastatic colorectal cancer.
Investigational
Matched Description: … ANX-510 (CoFactor) is a folate-based biomodulator drug being developed to enhance the activity and reduce …
Ado-P-Ch2-P-Ps-Ado
Experimental
Gibberellin A4
Experimental
Buloxibutid
Investigational
Aminopromazine
Experimental
Vet approved
Amcipatricin
Amcipatricin has been used in trials studying the treatment of Cryptococcosis or Aspergillosis Infections. Amcipatricin (as amcipatricin diascorbate; SPK-843) is a water-soluble partricin derivative patented by SPA Societa Prodotti Antibiotici S.p.A. and developed by Aparts and Kaken for the potential treatment of systemic fungal infections. In preclinical models, SPK-843 shows...
Investigational
Matched Description: … Amcipatricin (as amcipatricin diascorbate; SPK-843) is a water-soluble partricin derivative patented ... SPK-843 doses of higher than 1.0 mg/kg of body weight exhibit no renal toxicities and a tendency toward …
Nomacopan
Nomacopan is under investigation in clinical trial NCT03427060 (Coversin in PNH in Patients With Resistance to Eculizumab Due to Complement C5 Polymorphisms).
Investigational
Displaying drugs 5476 - 5500 of 11638 in total