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Displaying drugs 551 - 575 of 2624 in total
Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Synonyms: … Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate
Matched Description: … types of enzyme replacement therapy for the treatment of Pompe disease include [alglucosidase alfa] and ... cipaglucosidase alfa be granted marketing authorization for the treatment of Pompe disease,[L45275] and ... Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Experimental
Matched Synonyms: … Dihydronicotinamide-adenine dinucleotide phosphate ... Reduced nicotinamide adenine dinucleotide phosphate
Matched Iupac: … )oxy](hydroxy)phosphoryl}oxy)methyl]-4-hydroxyoxolan-3-yl]oxy}phosphonic acid ... [({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Enzymes and Coenzymes …
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop...
Approved
Investigational
Matched Synonyms: … Etacrinic acid ... Etacrynic acid ... Acide étacrynique …
Matched Name: … Etacrynic acid
Matched Iupac: … 2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid
Matched Description: … A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of ... Henle, but also in the proximal and distal tubules. ... This pharmacological action results in excretion of these ions, increased urinary output, and reduction …
Matched Categories: … Non Potassium Sparing Diuretics ... Sodium Potassium Chloride Symporter Inhibitors ... Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids
Matched Products: … Ethacrynic Acid ... Ethacrynic acid
Experimental
Matched Name: … Alpha-Benzyl-Aminobenzyl-Phosphonic Acid
Matched Iupac: … [(R)-(benzylamino)(phenyl)methyl]phosphonic acid
Bisphosphocin Nu-3 is under investigation in clinical trial NCT02737722 (Topically Applied Bisphosphocin Nu-3 on Infected Diabetic Ulcers of Subjects With Type I or II Diabetes Mellitus).
Investigational
Matched Synonyms: … 3'-thymidylic acid, monobutyl ester, 5'-(butyl hydrogen phosphate) …
Matched Iupac: … -1-yl)oxolan-2-yl]methoxy})phosphinic acid ... butoxy({[(2R,3S,5R)-3-{[butoxy(hydroxy)phosphoryl]oxy}-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin …
Mycophenolic acid is a potent immunosuppressant agent that inhibits de novo purine biosynthesis. It was derived from Penicillium stoloniferum, and has also shown antibacterial, antifungal and antiviral properties. . Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus)...
Approved
Investigational
Matched Synonyms: … Acido micofenolico ... Mycophenolic acid ... Micofenolico acido
Matched Name: … Mycophenolic acid
Matched Iupac: … (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
Matched Description: … [A249180] However, mycophenolic acid treatment is more expensive and requires therapeutic drug monitoring ... and antiviral properties. ... to optimize efficacy and minimize toxicity. …
Matched Categories: … Mycophenolic Acid and Prodrugs ... Antineoplastic and Immunomodulating Agents ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids
Matched Products: … Mycophenolic Acid ... Apo-mycophenolic Acid ... Mar-mycophenolic Acid
Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and...
Approved
Investigational
Matched Description: … [L45859] Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and antagonism ... of alpha-adrenergic and 5-HT2A receptors. ... treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and
Matched Categories: … Aripiprazole and prodrugs …
Matched Products: … Abilify Maintena 400 mg powder and solvent for prolonged-release suspension for injection ... ABILIFY MAINTENA POWDER AND SOLVENT FOR PROLONGED RELEASE SUSPENSION FOR INJECTION 400 MG …
An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Approved
Investigational
Matched Synonyms: … 6-Aminocaproic acid ... Aminocaproic acid ... 6-aminohexanoic acid
Matched Name: … Aminocaproic acid
Matched Iupac: … 6-aminohexanoic acid
Matched Mixtures name: … NAVI Black and C-Clinic ... Relief and Nature Toothpast E Jasmine Mint …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids
Matched Products: … Aminocaproic Acid ... Aminocaproic acid
Vespula squamosa venom protein is an extract of Vespula squamosa venom. Vespula squamosa venom protein is used in allergenic testing.
Approved
Matched Name: … Vespula squamosa venom protein …
Matched Description: … Vespula squamosa venom protein is an extract of Vespula squamosa venom. ... Vespula squamosa venom protein is used in allergenic testing. …
Matched Mixtures name: … Yellow Jacket Hymenoptera Venom Venomil Diagnostic ... Yellow Jacket Hymenoptera Venom Venomil Maintenance ... Mixed Vespid Hymenoptera Venom Venomil Maintenance …
Matched Categories: … Bee and Wasp Venom ... Standardized Insect Venom Allergenic Extract …
The phosphoric acid ester of serine.
Experimental
Matched Synonyms: … Serine phosphate
Matched Iupac: … (2S)-2-amino-3-(phosphonooxy)propanoic acid
Matched Description: … The phosphoric acid ester of serine. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Phosphoamino Acids
Experimental
Matched Synonyms: … Aracytidine 5'-phosphate ... Cytosine arabinose-5'-phosphate ... 1-beta-D-Arabinofuranosylcytosine 5'-phosphate
Matched Iupac: … acid ... {[(2R,3S,4S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic
Muparfostat (PI-88) is a mixture of highly sulfated, monophosphorylated mannose oligosaccharides, derived from the extracellular phosphomannan of the yeast Pichia (Hansenula) holstii, with potential antiangiogenic activity.
Investigational
Matched Synonyms: … Mannopentaose phosphate sulfate ... Sulfated mannopentaose phosphate ... -D-MANNAN, (1->3)-, 6-(DIHYDROGEN PHOSPHATE) TRIS(HYDROGEN SULFATE) …
Matched Iupac: … methyl]oxan-3-yl]oxy}oxan-4-yl]oxy}-6-[(phosphonooxy)methyl]-4,5-bis(sulfooxy)oxan-3-yl)oxidanesulfonic acid
Approved
Nutraceutical
Matched Synonyms: … Menadiol phosphate ... Menadiol bis(dihydrogen phosphate) …
Matched Iupac: … {[3-methyl-4-(phosphonooxy)naphthalen-1-yl]oxy}phosphonic acid
Experimental
Matched Synonyms: … D-Ribose 5-phosphate ... aldehydo-D-ribose 5-phosphate
Matched Name: … Ribose-5-phosphate
Matched Iupac: … {[(2R,3R,4R)-2,3,4-trihydroxy-5-oxopentyl]oxy}phosphonic acid
Matched Categories: … Sugar Phosphates
A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … Acidum citricum ... Anhydrous citric acid ... Citric acid,anhydrous …
Matched Name: … Citric acid
Matched Iupac: … 2-hydroxypropane-1,2,3-tricarboxylic acid
Matched Description: … It is an acid compound found in citrus fruits. ... The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability ... Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved …
Matched Mixtures name: … Potassium Citrate and Citric Acid ... Potassium Citrate and Citric Acid ... Potassium Citrate and Citric Acid
Matched Salts name: … Citric acid monohydrate …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Acyclic ... Acid Preparations ... citric acid ... Carboxylic Acids
Matched Products: … Citric Acid ... Citric Acid Wipes …
Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … .)-(118-145)-PEPTIDE (1-28) WITH HUMAN SOMATOTROPIN (GROWTH HORMONE, GH) (29-219) AND TWO TANDEM COPIES …
Matched Description: … adolescence and regulating metabolic function in adulthood. ... of somatrogon and allows its once-weekly dosing. ... by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Anterior Pituitary Lobe Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists …
Carbamoylcholine, also known as carbachol, is a muscarinic agonist discovered in 1932. Carbamoylcholine was initially used as a treatment for migraines, induction of diuresis, and other parasympathetic effects. Carbamoylcholine was granted FDA approval on 28 September 1972.
Approved
Matched Synonyms: … Choline carbamate
Matched Iupac: … 2-(trimethylazaniumyl)ethyl carbamate
Matched Description: … Carbamoylcholine was initially used as a treatment for migraines,[A226365] induction of diuresis,[A226370] and
Matched Categories: … Antiglaucoma Preparations and Miotics …
An aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis.
Experimental
Matched Synonyms: … Glyceraldehyde-3-phosphate ... D-Glyceraldehyde 3-phosphate
Matched Name: … D-glyceraldehyde 3-phosphate
Matched Iupac: … [(2R)-2-hydroxy-3-oxopropoxy]phosphonic acid
Matched Description: … An aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis. …
Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. ... Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. ... It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms …
Matched Mixtures name: … Isotonix Advanced B-complex Vitamins With Potassium and Magnesium ... Vena-Bal DHA ... Chela Potassium Plus …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Products: … Riboflavin 5 Phosphate Cap 50mg …
A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
Approved
Investigational
Matched Synonyms: … Estramustine 17-(dihydrogen phosphate) …
Matched Name: … Estramustine phosphate
Matched Iupac: … acid ... carbamoyl]oxy}-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]oxy}phosphonic
Matched Description: … A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also …
Investigational
Matched Synonyms: … Triciribine phosphate ... Pentaazaacenaphthylene-5' phosphate ester ... -D-RIBOFURANOSYL-1,4,5,6,8-PENTAAZAACENAPHTHYLENE 5'-(DIHYDROGEN PHOSPHATE) …
Matched Name: … Triciribine phosphate
Matched Iupac: … acid ... pentaazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,5,8,10-pentaen-2-yl}-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Fosbretabulin has been investigated for the treatment of Anaplastic Thyroid Cancer.
Investigational
Matched Synonyms: … Combretastatin A4 phosphate ... Combretastatin A-4 phosphate ... 2-METHOXY-5-((Z)-2-(3,4,5-TRIMETHOXYPHENYL)VINYL)PHENYL DIHYDROGEN PHOSPHATE
Matched Iupac: … {2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy}phosphonic acid
Investigational
Matched Synonyms: … Tmz-poh carbamate ... (s)-perillyl alcohol temozolomide carbamate ... Carbamic acid, n-((3,4-dihydro-3-methyl-4-oxoimidazo(5,1-d)-1,2,3,5-tetrazin-8-yl)carbonyl)-, ((4s)-4 …
Matched Iupac: … -2-yl)cyclohex-1-en-1-yl]methyl N-{3-methyl-4-oxo-3H,4H-imidazo[4,3-d][1,2,3,5]tetrazine-8-carbonyl}carbamate
Iocetamic acid is a diagnostic aid (radiopaque medium)
Approved
Matched Synonyms: … Iocetamic acid ... Acido iocetamico ... Acidum iocetamicum …
Matched Name: … Iocetamic acid
Matched Iupac: … 3-[N-(3-amino-2,4,6-triiodophenyl)acetamido]-2-methylpropanoic acid
Matched Description: … Iocetamic acid is a diagnostic aid (radiopaque medium) …
Matched Categories: … iocetamic acid
Experimental
Matched Synonyms: … 2'-Deoxy-5'-O-[(R)-hydroxy(phosphonoamino)phosphoryl]uridine …
Matched Iupac: … )amino]phosphonic acid ... [({[(2R,3S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl
Displaying drugs 551 - 575 of 2624 in total