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Displaying drugs 551 - 575 of 1092 in total

Betahistine

Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Description: … It has a significant impact on both the physical and social functioning of affected individuals. ... Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing ... [A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated …
Matched Products: … Betahist Forte Tablets 16mg ... VASOSERC FORT 16 MG TABLET, 60 ADET ... ROTASTIN FORT 16 MG TABLET, 60 ADET …

Dihydrocodeine

Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough. It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more effective antitussive agent to help reduce the spread of...
Approved
Illicit
Matched International brands: … DF-118 Forte …
Matched Description: … analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and ... It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more …
Matched Mixtures name: … dihydrocodeine bitartrate and aspirin and caffeine DC ... Acetaminophen, Caffeine and Dihydrocodeine Bitartrate ... Dihydrocodeine Bitartrate, Acetaminophen and Caffeine …
Matched Categories: … dihydrocodeine and paracetamol ... dihydrocodeine and acetylsalicylic acid …

Sufentanil

Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. It is administered by the intravenous, epidural and sublingual routes. Also known as Dsuvia, the sublingual form is used for the management of acute pain in adults that...
Approved
Investigational
Matched International brands: … Sufenta Forte …
Matched Description: … It is administered by the intravenous, epidural and sublingual routes. ... Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and ... analgesic in certified medically supervised healthcare settings, including hospitals, surgical centers, and …
Matched Categories: … Fentanyl and fentanyl analogues …

Sennosides

Sennosides (also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label] and empty the large intestine before surgery. The medication is taken by mouth or via the rectum[FDA Label]. It typically begins working in minutes when given by rectum and within twelve hours when given...
Experimental
Matched Description: … also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label][L771] and ... It typically begins working in minutes when given by rectum and within twelve hours when given by mouth …
Matched Mixtures name: … Senna and Docusate Sodium ... Senna and Docusate Sodium ... Sennosides and Docusate Sodium …
Matched Salts name: … Sennosides A and B …
Matched Categories: … Drugs for Constipation ... Alimentary Tract and Metabolism ... Herbs and Natural Products …
Matched Products: … Lax-Aid for Children ... Only For STIMULANT LAXATIVE ... SENOKOT FORT 15 MG TABLET, 30 ADET …

Iltamiocel

Investigational
Matched Synonyms: … THE EXPANSION IS CONSISTENT WITH ROUTINE CELL CULTURE PRACTICES FOR ADHERENT CELLS. …

Gemcitabine

Gemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers. Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose. As a prodrug, gemcitabine is transformed...
Approved
Matched Description: … for various cancers. ... It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy ... Gemcitabine is a nucleoside analog and a chemotherapeutic agent. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … GEMZAR 1gm POWDER FOR SOLUTION FOR INFUSION ... GEMZAR 200mg Powder for Solution for Infusion ... DBL Gemcitabine Powder for Solution for Injection 1g …

Levodropropizine

Levodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine).
Investigational
Matched Description: … Levodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and …
Matched Categories: … Cough and Cold Preparations …
Matched Products: … LEVOZOPIN FORT 60MG/5ML ŞURUP, 75 ML ... LEVOPRONT FORT 60 MG/5 ML ŞURUP, 75 ML ... LEVOSOL FORT 60 MG / 5 ML ŞURUP, 75 ML …

Ceftaroline fosamil

Ceftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and skin structure infections. Community-acquired bacterial pneumonia.
Approved
Investigational
Matched Description: … caused by designated susceptible bacteria: Acute bacterial skin and skin structure infections. ... Ceftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Zinforo 600mg Powder for Concentrate for Solution for Infusion ... Zinforo Powder for Concentrate for Solution for Infusion 600mg/vial …

Daratumumab

Daratumumab is an immunoglobulin G1 kappa monoclonal antibody developed by Janssen and Genmab. It was first described in the literature in 2010 as a monoclonal antibody that targets CD38+ multiple myeloma cells; the first of its kind. Daratumumab was granted FDA approval on 16 November 2015. It is approved for...
Approved
Matched Description: … [L13290] It is approved for the treatment of multiple myeloma as monotherapy or combination therapy and ... Daratumumab is an immunoglobulin G1 kappa monoclonal antibody developed by Janssen and Genmab. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … DARZALEX CONCENTRATE FOR SOLUTION FOR INFUSION 400MG/20ML ... DARZALEX CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/5ML ... Darzalex 20mg/mL Concentrate for Solution for Infusion …

(3-Formyl-but-3-Enyl)-Phosphonic Acid

Experimental
Matched Name: … (3-Formyl-but-3-Enyl)-Phosphonic Acid …

5-Formyl-2'-deoxy-cytidine-5'-monophosphate

Experimental
Matched Name: … 5-Formyl-2'-deoxy-cytidine-5'-monophosphate …
Matched Iupac: … {[(2R,3S,5R)-5-(4-amino-5-formyl-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic …

Vedolizumab

Vedolizumab is a recombinant humanized IgG1 monoclonal antibody directed against the human lymphocyte α4β7 integrin, a key mediator of gastrointestinal inflammation implicated in diseases like ulcerative colitis or Crohn's disease. α4β7 integrin facilitates the interaction between lymphocytes and gut endothelial cells through the α4β7 integrin-MAdCAM1 interaction, leading to the mobilization...
Approved
Matched Description: … for the maintenance therapy of moderately to severely active Ulcerative Colitis and Crohn’s Disease in ... April and September 2023, respectively. ... six weeks and then every 8 weeks thereafter. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Entyvio 300mg Powder for Concentrate for Solution for Infusion ... ENTYVIO POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 300MG/VIAL …

Bendamustine

Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine...
Approved
Investigational
Matched Description: … a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and ... Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks ... It is active against both active and quiescent cells, although the exact mechanism of action is unknown …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … BEMUNAT POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 25 MG/VIAL USP ... BEMUNAT POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100 MG/VIAL USP ... RIBOMUSTIN 25MG/VIAL POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION …

Bevacizumab

There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells.[A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a therapeutic target for anti-cancer...
Approved
Investigational
Matched Description: … [A193272,A193275] It is a humanized monoclonal IgG antibody, and inhibits angiogenesis by binding and ... the survival and proliferation of cancer cells. ... regimens which are specific to the type, severity, and stage of cancer. …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ZIRABEV CONCENTRATE FOR SOLUTION FOR INFUSION 100 MG/4 ML ... ZIRABEV CONCENTRATE FOR SOLUTION FOR INFUSION 400 MG/16 ML ... MVASI CONCENTRATE FOR SOLUTION FOR INFUSION 25 MG/ML …

Pertuzumab

Pertuzumab is a recombinant humanized monoclonal antibody that targets the extracellular dimerization domain (subdomain II) of the human epidermal growth factor receptor 2 protein (HER2). It consists of two heavy chains and two lights chains that have 448 and 214 residues respectively. It was first approved by the FDA in...
Approved
Matched Description: … It was first approved by the FDA in 2012 for use with [docetaxel] and another HER2-targeted monoclonal ... It consists of two heavy chains and two lights chains that have 448 and 214 residues respectively. ... Its indicated conditions have since expanded to include use as both a neoadjuvant therapy and an adjuvant …
Matched Categories: … Amino Acids, Peptides, and Proteins ... pertuzumab and trastuzumab ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … Perjeta 420 mg concentrate for solution for infusion ... PERJETA CONCENTRATE FOR SOLUTION FOR INFUSION 420MG/14ML ... PHESGO SOLUTION FOR SUBCUTANEOUS INJECTION 600 MG/600 MG / 10 ML …

Mepolizumab

Eosinophils are involved in inflammatory immune responses, and prolonged hypereosinophilia (typically defined as absolute eosinophil levels of 1500/mm3 or more) is associated with a spectrum of diseases, including severe asthma, eosinophilic granulomatosis with polyangiitis (EGPA), and hypereosinophilic syndrome (HES). The pathogenesis of eosinophilia is complex, but IL-5 is recognized as...
Approved
Investigational
Matched Description: … Mepolizumab was first approved by the FDA on November 4, 2015, as an add-on therapy for severe asthma ... Activated eosinophils further stimulate an inflammatory response and also induce tissue lesions and promote ... and marketed under the brand name Nucala by GlaxoSmithKline. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs for Obstructive Airway Diseases …
Matched Products: … NUCALA POWDER FOR SOLUTION FOR INJECTION 100mg ... Nucala 100mg Powder for Solution for Injection ... NUCALA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML …

Azacitidine

Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. One of them is the induction of cytotoxicity. As an analogue of cytidine, it...
Approved
Investigational
Matched Description: … As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and ... inhibiting protein and DNA synthesis. ... [A1407] Due to its anti-neoplastic activity and its ability to inhibit methylation in replicating DNA …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Azacitidine For ... Vidaza powder for suspension for injection 100mg/vial ... AZADINE POWDER FOR SUSPENSION FOR INJECTION 100MG/VIAL …

Erenumab

Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines. Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the first and only...
Approved
Investigational
Matched Description: … Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the ... Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and ... first and only FDA approved treatment specifically developed to prevent migraine by blocking the CGRP …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … AIMOVIG (140 MG/ML SOLUTION FOR INJECTION) ... AIMOVIG (70 MG/ML SOLUTION FOR INJECTION) ... AIMOVIG SOLUTION FOR INJECTION IN PRE-FILLED PEN 70MG/ML …

APTO-253

Investigational
Matched Synonyms: … Lt-253(former code) ... Lor-253(former code) …

Irinotecan

Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Description: … Irinotecan is a topoisomerase inhibitor used for chemotherapy. ... Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking ... This leads to the arrest of the cell cycle in the S-G2 phase and cancer cell death.[A263376] …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … IRITEC CONCENTRATE FOR SOLUTION FOR INFUSION 40mg/2ml ... IRITEC CONCENTRATE FOR SOLUTION FOR INFUSION 100mg/5ml ... Inotecam 20mg/ml Concentrate for Solution for Infusion …

Aflibercept

Aflibercept is a recombinant protein composed of the binding domains of two human vascular endothelial growth factor (VEGF) receptors, VEGFR1 and VEGFR2, fused with the Fc region of human immunoglobulin gamma 1 (IgG1). Structurally, Aflibercept is a dimeric glycoprotein with a protein molecular weight of 96.9 kilo Daltons (kDa). It...
Approved
Matched Description: … the treatment of retinopathy of prematurity in preterm infants in February 2023 and for the treatment ... and February 2013, respectively. ... the treatment of metastatic colorectal cancer, and it was approved by the FDA and EMA in August 2012 …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Zaltrap 25mg/ml Concentrate for Solution for Infusion ... ZALTRAP CONCENTRATE FOR SOLUTION FOR INFUSION 25 MG/ML ... EYLEA SOLUTION FOR INJECTION IN VIAL 2MG …

Atezolizumab

Atezolizumab is a humanized monoclonal antibody used to prevent the interaction of PD-L1 and PD-1, removing inhibition of immune responses seen in some cancers.[A18493,L7489] This medication is reserved for patients whose tumors express PD-L1, cannot receive platinum-based chemotherapy, or whose tumors do not respond to platinum-based chemotherapy. Atezolizumab was granted...
Approved
Investigational
Matched Description: … Atezolizumab is a humanized monoclonal antibody used to prevent the interaction of PD-L1 and PD-1, removing ... [L7489] In November 2022, the manufacturer (Genentech) voluntarily withdrew the use of atezolizumab for ... [A18493,L7489] This medication is reserved for patients whose tumors express PD-L1, cannot receive platinum-based …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … TECENTRIQ CONCENTRATE FOR SOLUTION FOR INFUSION 840MG/14ML ... Tecentriq 60mg/ml Concentrate for Solution for Infusion ... TECENTRIQ CONCENTRATE FOR SOLUTION FOR INFUSION 1200 MG/ 20 ML …

Burosumab

Burosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic rickets . The U.S. Food and Drug Administration approved Crysvita (burosumab) in April 2018. This is the first drug approved...
Approved
Investigational
Matched Description: … (XLH), which is a rare, inherited form of rickets. ... It causes impaired bone growth and development in children and adolescents and issues with bone mineralization ... This is the first drug approved to treat adults and children ages 1 year and older with X-linked hypophosphatemia …
Matched Categories: … Drugs for Treatment of Bone Diseases ... Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … CRYSVITA 10 MG SOLUTION FOR INJECTION ... CRYSVITA 20 MG SOLUTION FOR INJECTION ... CRYSVITA 30 MG SOLUTION FOR INJECTION …

Fludarabine

Fludarabine is a chemotherapeutic agent used in the treatment of hematological malignancies. It is commonly marketed under the brand name Fludara.
Approved
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … FLUDARABINE PHOSPHATE POWDER FOR SOLUTION FOR INJECTION/ INFUSION USP ... Fludarabine Kabi 50mg Lyophilized Powder for Solution for Injection or Infusion ... Fludarabine Sandoz 50 mg/2ml concentrate for solution for injection or infusion …

Alglucosidase alfa

Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell...
Approved
Matched Description: … It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients. ... Alglucosidase alfa degrades glycogen by catalyzing the hydrolysis of a-1,4- and a-1,6- glycosidic linkages ... residue mature polypeptide chain, and a total mass of approximately 109,000 daltons, including carbohydrates …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Products: … Myozyme Powder for Solution for Injection ... (Alglucosidase alfa) 50mg Powder for Solution for Infusion …
Displaying drugs 551 - 575 of 1092 in total